• Title/Summary/Keyword: Chemical companies

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Creation of System Dynamics in an Uncertain and Complex Market: The Case of Korea's Evolving Biopharmaceutical Industry

  • Lee, Jeong Hyop;Kim, Jaewon;Hyeon, Byung-Hwan
    • Asian Journal of Innovation and Policy
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    • v.8 no.2
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    • pp.180-207
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    • 2019
  • This article explores the historical evolutionary process of the biopharmaceutical industry of Korea, and how intentional and unintentional policy interventions have triggered the creation of the industry's system dynamics and paved the way for the generation of a few global leading products, including biosimilar, as well as next-generation therapeutics of gene and cell. The policies cover the simple technology transfer of API synthesis to overcome the endemic parasitic disease, new substance patent adoption and new drug development consortia, human resource development, various national initiatives influenced by the Human Genome Project, and venture promotion schemes. The scope and implementation tools under these policies have been aligned and refined to transform traditional fine chemical-based pharmaceuticals, to stimulate large companies' participation and to create technology-based venture companies in the biopharma business of Korea.

A Study on the Development of Self-Checklists for Small and Medium-Sized Chemical Industries (중소규모 화학업종을 위한 자율점검표 개발 연구)

  • Woo Sub Shim;Kyeong-Seok Oh
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.5
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    • pp.757-763
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    • 2023
  • Major industrial accidents in which workers die due to fires or explosions while working at chemical substance handling workplaces continue to occur. Among the major industrial accidents that occurred between 2005 and 2021, the accident status by work situation and equipment was analyzed. Through analysis, it was confirmed that storage, reaction, and piping facilities were the main causes of the accident, and a self-checklist for each facility was developed. Verification was conducted through the supply and use groups to evaluate the suitability of the use, duties, and items of the self-checklist. The user group showed higher satisfaction than the supplier group for all three suitability of use, job, and item. In particular, since the inspection items of the self-checklist were organized around the cause of the accident derived through the analysis of actual accident cases, the satisfaction level was high in all groups. It is expected that the self-checklist developed through this study will be useful not only for large companies but also for small and medium-sized chemical industries that lack professional manpower.

Operation Modes Classification of Chemical Processes for History Data-Based Fault Diagnosis Methods (데이터 기반 이상진단법을 위한 화학공정의 조업모드 판별)

  • Lee, Chang Jun;Ko, Jae Wook;Lee, Gibaek
    • Korean Chemical Engineering Research
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    • v.46 no.2
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    • pp.383-388
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    • 2008
  • The safe and efficient operation of the chemical processes has become one of the primary concerns of chemical companies, and a variety of fault diagnosis methods have been developed to diagnose faults when abnormal situations arise. Recently, many research efforts have focused on fault diagnosis methods based on quantitative history data-based methods such as statistical models. However, when the history data-based models trained with the data obtained on an operation mode are applied to another operating condition, the models can make continuous wrong diagnosis, and have limits to be applied to real chemical processes with various operation modes. In order to classify operation modes of chemical processes, this study considers three multivariate models of Euclidean distance, FDA (Fisher's Discriminant Analysis), and PCA (principal component analysis), and integrates them with process dynamics to lead dynamic Euclidean distance, dynamic FDA, and dynamic PCA. A case study of the TE (Tennessee Eastman) process having six operation modes illustrates the conclusion that dynamic PCA model shows the best classification performance.

Investigation Study of Information Improvement in Chemical Accident by Extraordinary Chemical Reaction (이상반응 화학사고 정보제공 개선 연구)

  • Kim, Sungbum;Lim, Myunghee;Park, Joongdon
    • Journal of the Society of Disaster Information
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    • v.11 no.2
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    • pp.219-225
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    • 2015
  • Hydrofluoric acid leakage accident was occurred on Dec. 2012 in Hube Global. That accident has bought many changes of response in national organizations. Chemical companies respond quickly even when small quantities leakage of chemicals and response agencies were put a lot of manpower and equipment in incident response. Incident response to the response activities of the agents is difficult if the accident substance was not identified. Unknown chemicals can be generated by the water for fire-fighting during the emergency response process. In this case, an additional information was needed for response of chemical accident to prevent of great damage. In this study, we investigated the improvement of chemical accident information by extraordinary chemical accident.

The Current Status and Recommendation of Work Environment Management in Small Scale Industry with less than 5 Workers (경인지역 일부 5인미만 사업장 근로자의 작업환경실태와 관리대책)

  • Kim, Dea Sic;Roh, Youngman;Kim, Hyun Wook;Jeong, Chun Hwa;You, Ki ho
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.11 no.3
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    • pp.179-189
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    • 2001
  • This study was performed to identify the current status of work environment management and to provide appropriate recommendations for small scale industry with less than 5 workers from September, 2000 to October, 2000 in Seoul city and Gyoung-gi province. The 211 companies were surveyed by checklist included the elements of management of work environment, hazardous chemicals, MSDS, personal protective equipment, and ventilation system. The proportion of metal products manufacturing and printing industries are 25.6 % and 22.3%, respectively. The daily working hours in printing industry is longer than others. The industries that produce potentially hazardous agents, such as noise, dust, metal, organic solvents, radiation and chemical material are pulp, plating, machinery, and printing, respectively. In above industries, only 2.8 % of those recognised and had MSDS. The proportion of companies providing fire extinguishers, safety showers are found to be 13.3 %, 7.1 %, respectively. Only 24.2 % of companies provided personal protective equipment to the workers. The ventilation system was operated in most of companies. But local exhaust ventilation system is provided to 22.3 % of those, also had not been annually inspected. This study showed that the current status of occupational safety and health was not appropriate for workers in small scale industries. It is suggested that annual physical examination have to be performed, MSDS usage must become widespread, and employer and emplyees in small scale industry should be educated for the treatment and storage of hazardous chemicals to improve the occupational safety and health of the working environment. also, regulatory standard has to be applied to local exhaust ventilation system in small scale industry to improve the working condition.

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Physicochemical, Microbiological and Sensory Properties of Korean Frozen Pork Loins for Export (한국산 수출용 냉동 돈육 등심의 물리화학적, 미생물학적 및 관능적 품질특성)

  • Choi, Y.S.;Kim, J.H.;Park, B.Y.;Lee, J.M.;Kim, I.S.;Kim, B.C.
    • Journal of Animal Science and Technology
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    • v.44 no.3
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    • pp.361-368
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    • 2002
  • The Korean frozen pork loins in vacuum packaged were obtained from three different Korean export companies and investigated for pH, proximate composition, cooking loss, physico-chemical and sensory characteristics. The frozen pork loins were stored at -20$^{\circ}C$ for 40 days. The results were as follows: The protein contents were relatively higher in the samples from the company II and the ash contents were relatively higher in the samples from the company I than those from the other companies. The samples from the company Ⅱ had highest pH and water-holding capacity, and cooking loss and shear force were lowest in the company II. The total plate counts and coliform bacteria for loins from 3 companies were in the range of 3.04${\sim}$3.75 log cfu/$cm^2$ or g and 0.37${\sim}$1.32 log cfu/$cm^2$ or g in average, respectively. The TBARS values were 0.35${\sim}$0.38 mg malonaldehyde/kg sample. There were no significant differences in sensory characteristics for raw and cooked loins from all companies.

A study on the comparative test of chemical and thermal properties of virgin and recycled PET products (버진 및 리사이클 PET 제품의 화학적·열적 특성 비교시험에 관한 연구)

  • Kim, Kyoung Pil;Seo, Kyung Jin;Park, Soo-Yong;Chung, Ildoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.33-39
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    • 2021
  • As the interest and demand in the recycled yarn field has increased rapidly worldwide, domestic companies are also promoting research and development and business on recycled yarn. The chemical and thermal properties of four types of virgin and recycled PET samples from A and B company, which are the leading domestic companies in the recycled polyester yarn business, were confirmed through infrared (FT-IR) spectroscopy and differential scanning calorimetry (DSC). Virgin and recycled PET from two companies were compared. FT-IR spectroscopy revealed the typical spectra of PET for both companies and a different peak at 872 cm-1. DSC confirmed that the melting point and crystallization temperature of recycled PET were lower than those of virgin PET. These results indicate that small amounts of contaminants are an important parameter affecting the thermal properties of recycled PET. In the DSC results after seven repeats of the heating and cooling processes, all four samples showed that a lower melting point, crystallization temperature, and low heat flow intensity increased with increasing number of cycles. The results of melting and crystallization enthalpy also showed similar patterns.

Insulin Releasing Polymers for Treatment of Diabetes

  • Kim, S.W.;T. Okano;L.A. Seminoff;Jeong, Seo-Young
    • Journal of Biomedical Engineering Research
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    • v.7 no.2
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    • pp.113-116
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    • 1986
  • We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies.

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Comparison of Polyphenylene Sulfide Composites Having Different Processing Temperatures and Glass Fibers

  • Jeong, Do Yeon;Yoo, Seung Yong;Jung, Chan-Gyu;Lee, Jaeyong;Kim, Sang Hoon;Lee, Pyeong-Chan;Lee, Hyun Wook;Ha, Jin Uk
    • Elastomers and Composites
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    • v.54 no.4
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    • pp.308-312
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    • 2019
  • Polyphenylene sulfide (PPS) is a well-known super engineering plastic with a high melting temperature (above 290℃). It is generally insoluble under regular conditions. Therefore, it can be used for replacing metallic materials. Many researchers are looking at the possibility of replacing aluminum in the engine compartment of an automobile. However, studies on PPS are not common as compared to conventional engineering plastics because only a few companies produce super engineering plastics. In this research, the material properties of PPS composites containing two different kinds of glass fibers and produced under different processing temperatures were investigated. The tensile strength of the PPS composites increased as the processing temperature increased. Although glass fibers with similar aspect ratios were compounded under the same processing condition, one of them yielded a higher mechanical strength.

Methodology of the Fuel Conversion Project and Analysis of the Offset System of the Greenhouse Gas Emission Trading System (연료 전환 사업의 방법론과 온실가스 배출권거래제 상쇄제도 분석)

  • Kim, Eok yong;Shin, Min chang;Park, Jeong hoon
    • Korean Chemical Engineering Research
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    • v.60 no.4
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    • pp.478-485
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    • 2022
  • The certification performance issued through an external business is sold to companies subject to the emission trading system allocation, and the company subject to the allocation can secure the quota by converting the purchased external business certification performance into offset credits. In this methodology, when fossil fuels that used existing oil boilers (by oil type) were replaced with boilers using propane gas with a relatively low carbon content, the amount of carbon dioxide emission reduction by oil type was recognized. As an initial analysis to make up for the insufficient quota of large corporations, the amount of carbon reduction emissions and emission rights trading was calculated.