• 제목/요약/키워드: Chemical Modification

검색결과 1,279건 처리시간 0.026초

임상가를 위한 특집 1 - 티타늄 임플란트의 골융합 증진을 위한 최신 표면처리 기술 (Advanced Surface Modification Techniques for Enhancing Osseointegration of Titanium Implant)

  • 송호준
    • 대한치과의사협회지
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    • 제48권2호
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    • pp.96-105
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    • 2010
  • Titanium implant is used as the most popular dental material for replacement of missing teeth recently. A lot of studies on the surface modification of titanium implant have been carried out for enhancing osseointegration. The surface modification techniques could be classified as follows; topographic modifications which provide roughness and porosity, chemical surface modificationss or deposition of osseoconductive materials, and biochemical modifications to immobilize bone growth factors on titanium surface. In this study, the current and ongoing surface modification techniques and its typical characteristics used in clinics were reviewed. In the future, study and implication about biochemical modifications including patient' s individual characteristics will be important.

액정의 광배향을 위한 폴리이미드의 표면 변형 (Modification of Polyimide Surface for Photo-Alignment in LCD)

  • 신동명;송동미;손병청;강도열
    • 한국응용과학기술학회지
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    • 제15권3호
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    • pp.47-53
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    • 1998
  • The polyimide film surface was modified with KOH aqueous solutions or sulfuric acid. The film thickness was increased by about 10% through the modification of film surface. Hydrolysis of amide bonds and hydration of water induced the increase. The polarity of the film surface increased and identified by contact angle measurement. The depth and roughness of modified was increased. After treatment of surface with water, alkyl and 4-pentyloxyaniline were introduced on the film surface by complex formation between anionic species formed on the imide surface and ammonium ion. The newly introduced alkyl group was identified by FT-IR spectroscopy. Surface polarity reduced dramatically and the roughness was increased after introduction of ammonium salt.

Chemical Modification of Cysteine Residues in Hafnia alvei Aspartase by NEM and DTNB

  • Shim, Joon-Bum;Kim, Jung-Sung;Yoon, Moon-Young
    • BMB Reports
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    • 제30권2호
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    • pp.113-118
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    • 1997
  • Aspartase from Hafnia alvei was inactivated by N-ethylmaleimide (NEM) and 5,5' -Dithiobis-(2-znitrobenzoic acid) (DTNB) following pseudo-first order kinetics. Their apparent reaction orders were 0.83 and 0.50 for NEM and DTNB modifications, respectively, indicating that inactivation was due to a sulfhydryl group in the active site of aspartase and participation of the sulfhydryl group in an essential step in the catalytic reaction. When aspartase was modified by DTNB, the enzyme activity was restored by dithiothreitol treatment, indicating that cysteine residuetsl islarel possibly at or near the active site. The pH-dependence of the inactivation rate by NEM suggested that an amino acid residue having pK value of 8.3 was involved in the inactivation. When aspartase was incubated with NEM and L-aspartate together, L-aspartate markedly protected the enzyme from inactivation by NEM, but the other reagents used did not.

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Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis

  • Park, Hyun-Gyu;Do, Jin-Hwan;Chang, Ho-Nam
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제8권1호
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    • pp.1-8
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    • 2003
  • With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.

화학공장의 변경관리전산시스템(K-MOC) 개발 (Development of Changing Management Software(K-MOC) for Chemical Plant)

  • 권혁면;백종배
    • 한국안전학회지
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    • 제21권1호
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    • pp.72-78
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    • 2006
  • In many chemical plants the change or modification is carried out without proper technical review and hazard analysis, and also without adequate technical staff and procedures for comprehensive monitoring of potential hazards resulting from the change. Such changes sometimes affect to the process safety badly if it is not managed properly. Therefore, in order to prevent major industrial accidents caused by change or modification, and also in order to apply Management of Change procedure easily in the field and minimize economic burden of company caused by plant changes, K-MOC(KOSHA-Management of Change) software has been developed and provided to the chemical industry.

A Facile Process for Surface Modification with Lithium Ion Conducting Material of Li2TiF6 for LiMn2O4 in Lithium Ion Batteries

  • Kim, Min-Kun;Kim, Jin;Yu, Seung-Ho;Mun, Junyoung;Sung, Yung-Eun
    • Journal of Electrochemical Science and Technology
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    • 제10권2호
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    • pp.223-230
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    • 2019
  • A facile method for surface coating with $Li_2TiF_6$ which has a high lithium-ion conductivity, on $LiMn_2O_4$ spinel cathode material for high performance lithium ion batteries. The surface coating is performed by using a co-precipitation method with $Li_2CO_3$ powder and $H_2TiF_6$ solution under room temperature and atmospheric pressure without special equipment. Total coating amount of $Li_2TiF_6$ is carefully controlled from 0 to 10 wt.% based on the active material of $LiMn_2O_4$. They are evaluated by a systematic combination of analyses comprising with XRD, SEM, TEM and ICP. It is found that the surface modification of $Li_2TiF_6$ is very beneficial to high cycle life and excellent rate capability by reducing surface failure and supporting lithium ions transportation on the surface. The best coating condition is found to have a high cycle life of $103mAh\;g^{-1}$ at the 100th cycle and a rate capability of $102.9mAh\;g^{-1}$ under 20 C. The detail electrochemical behaviors are investigated by AC impedance and galvanostatic charge and discharge test.