• Journal of the Optical Society of Korea
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• 제18권3호
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• pp.244-250
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• 2014

Due to the difficulty in measuring very low out-of-band cutoff depths of solar blind UV filters, we propose a cutoff depth adjustable measurement system (CDAM) to test deep cutoff filters with a large dynamic range. The CDAM utilizing the substitution method is elaborately composed of several parts, including narrow-band LED light sources, standard reflective neutral attenuators with known attenuation coefficients, and a photomultiplier (PMT). This paper also presents an attenuator combination method ensuring that the PMT works within its linear response range. In addition, numerical simulation testifies to the method, and experiment shows that the CDAM system can achieve an extension of dynamic range from 0-6 OD to 0-10 OD, which is sufficient for the measurement of out-of-band cutoff depths of solar blind UV filters. Above all, the CDAM system, being easily implemented, of wide dynamic range, and highly precise, could be widely used in the measurement of filter cutoff depth.

• Current Optics and Photonics
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• 제1권1호
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• pp.23-28
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• 2017

The laser has been regarded as the potential illumination source for the next generation of projectors. However, currently the major issues in applying the laser as an illumination source for projectors are beam shaping and laser speckle. We present a compact solution for both issues by using a vibrating diffractive optical element (DOE). The DOE is designed and fabricated, and it successfully transforms the circular Gaussian laser beam to a low speckle contrast uniform rectangular pattern. Under a vibration frequency of 150 Hz and amplitude of $200{\mu}m$, the speckle contrast value is reduced from 67.67% to 13.78%, and the ANSI uniformity is improved from 24.36% to 85.54%. The experimental results demonstrate the feasibility and potential of the proposed scheme, and the proposed method is a feasible approach to the miniaturization of laser projection display illumination systems.

• Journal of Ginseng Research
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• 제43권1호
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• pp.27-37
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• 2019

Background: The structural conversions in ginsenosides induced by steaming or heating or acidic condition could improve red ginseng bioactivities significantly. In this paper, the chemical transformations of red American ginseng from fresh Panax quinquefolium L. under steaming were investigated, and the possible mechanisms were discussed. Methods: A method with reversed-phase high-performance liquid chromatography coupled with linear ion trap mass spectrometry ($HPLC-MS^n$)-equipped electrospray ionization ion source was developed for structural analysis and quantitation of ginsenosides in dried and red American ginseng. Results: In total, 59 ginsenosides of protopanaxadiol, protopanaxatriol, oleanane, and ocotillol types were identified in American ginseng before and after steaming process by matching the molecular weight and/or comparing $MS^n$ fragmentation with that of standards and/or known published compounds, and some of them were determined to be disappeared or newly generated under different steaming time and temperature. The specific fragments of each aglycone-type ginsenosides were determined as well as aglycone hydrated and dehydrated ones. The mechanisms were deduced as hydrolysis, hydration, dehydration, and isomerization of neutral and acidic ginsenosides. Furthermore, the relative peak areas of detected compounds were calculated based on peak areas ratio. Conclusion: The multicomponent assessment of American ginseng was conducted by $HPLC-MS^n$. The result is expected to provide possibility for holistic evaluation of the processing procedures of red American ginseng and a scientific basis for the usage of American ginseng in prescription.

• Journal of Ginseng Research
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• 제46권2호
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• pp.290-295
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• 2022

Background: Dried and red ginseng are well-known types of processed ginseng and are widely used as healthy food. The dried and red ginseng quality may vary with the storage period of raw ginseng. Therefore, herein, the effect of the storage period of fresh ginseng on processed ginseng quality was evaluated through multicomponent quantification with statistical analysis. Methods: A method based on ultrahigh performance liquid chromatography coupled to triple quadrupole mass spectrometry in multiple-reaction monitoring mode (UPLC-MRM-MS) was developed for quantitation of ginsenosides and oligosaccharides in dried and red ginseng. Principal component analysis and partial least squares discriminant analysis were conducted to evaluate the dynamic distributions of ginsenosides and oligosaccharides after different storage periods. Results: Eighteen PPD, PPT and OLE ginsenosides and nine reducing and nonreducing oligosaccharides were identified and quantified. With storage period extension, the ginsenoside content in the processed ginseng increased slightly in the first 2 weeks and decreased gradually in the following 9 weeks. The content of reducing oligosaccharides decreased continuously as storage time extending, while that of the nonreducing oligosaccharides increased. Chemical conversions occurred during storage, based on which potential chemical markers for the storage period evaluation of fresh ginseng were screened. Conclusion: According to ginsenoside and oligosaccharide distributions, it was found that the optimal storage period was 2 weeks and that the storage period of fresh ginseng should not exceed 4 weeks at 0 ℃. This study provides deep insights into the quality control of processed ginseng and comprehensive factors for storage of raw ginseng.

• 대한간호학회지
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• 제51권6호
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• pp.746-757
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• 2021

Purpose: The purpose of this study was to explore the factors influencing the occupational attitudes of nursing students in the probation period. Methods: Nursing students in the probation period from five hospitals completed an anonymous survey. The instruments included the nursing occupational attitude scale, family adaptability, partnership, growth, affection, and resolve index, and perceived social support scale. The study examined the moderation model between family function, perceived social support, and occupational attitudes using PROCESS 3.2. Results: For nursing students, when social support was low, family function had a significant positive impact on occupational attitudes and intentions, and the effect was much higher than that of perceived social support. Conclusion: Family function has a significant positive explanatory effect on attitude and intention (β = .13, p < .001 and β = .12, p < .001); the interaction term between family function and perceived social support are significant (β = .01, p < .001 and β = .01, p < .001). Perceived social support has a significant moderating effect on the relationship between family function and occupational attitudes of nursing students in the probation period. Family function has a significant difference in the occupational attitudes and intentions of nursing students with low perceived social support. Nursing students perceive social support in the probation period has a significant moderation effect in the relationship between their family function and occupational attitudes. Interns with low family function should be given more social support to improve their occupational attitudes.

• Journal of Ginseng Research
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• 제43권4호
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• pp.508-516
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• 2019

Background: Ginsenosides are not only the principal bioactive components but also the important indexes to the quality assessment of Panax ginseng Meyer. Their contents in cultivated ginseng vary with the growth environment and age. The present study aimed at evaluating the significant difference between 36 cultivated ginseng of different cultivation areas and ages based on the simultaneously determined contents of 14 ginsenosides. Methods: A high-performance liquid chromatography (HPLC) coupled with triple quadrupole mass spectrometer (MS) method was developed and used in the multiple reaction-monitoring (MRM) mode (HPLC-MRM/MS) for the quantitative analysis of ginsenosides. Multivariate statistical analysis, such as principal component analysis and partial least squares-discriminant analysis, was applied to discriminate ginseng samples of various cultivation areas and ages and to discover the differentially accumulated ginsenoside markers. Results: The developed HPLC-MRM/MS method was validated to be precise, accurate, stable, sensitive, and repeatable for the simultaneous determination of 14 ginsenosides. It was found that the 3- and 5-yr-old ginseng samples were differentiated distinctly by all means of multivariate statistical analysis, whereas the 4-yr-old samples exhibited similarity to either 3- or 5-yr-old samples in the contents of ginsenosides. Among the 14 detected ginsenosides, Rg1, Rb1, Rb2, Rc, 20(S)-Rf, 20(S)-Rh1, and Rb3 were identified as potential markers for the differentiation of cultivation ages. In addition, the 5-yr-old samples were able to be classified in cultivation area based on the contents of ginsenosides, whereas the 3- and 4-yr-old samples showed little differences in cultivation area. Conclusion: This study demonstrated that the HPLC-MRM/MS method combined with multivariate statistical analysis provides deep insight into the accumulation characteristics of ginsenosides and could be used to differentiate ginseng that are cultivated in different areas and ages.

• Journal of the Optical Society of Korea
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• 제19권1호
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• pp.84-87
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• 2015

For large optical elements which are tested by many sub-apertures, it takes too much time for a sub-aperture stitching algorithm to get the stitching result. To solve this problem, we propose a fast sub-aperture stitching algorithm to quickly compensate for piston, tilt, and defocus errors. Moreover, the new algorithm is easy to understand and program. We use partial derivatives of measurement data to separately solve piston, tilt, and defocus errors. First, we show that the new algorithm has a lower time complexity than the currently used algorithm. Although simulation results indicate that the accuracy of the new algorithm is lower than the current algorithm in all 20 simulations, our experimental results validate the algorithm and show it is sufficiently accurate for general use.

• Journal of the Optical Society of Korea
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• 제20권2호
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• pp.314-320
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• 2016

The glass thermal forming process provides a high volume, low cost approach to producing aspherical reflectors for x-ray optics. Thin glass sheets are shaped into mirror segments by replicating the mold shape at high temperature. Heating parameters in the glass thermal slumping process are crucial to improve surface quality of the formed glass. In this research, the heating process of a thermal slumping glass sheet on a concave parabolic mold was simulated with the finite-element method (FEM) to investigate the effects of heating rate and soaking temperature. Based on the optimized heating conditions, glass samples 0.5 mm thick were formed in a furnace with a steel concave parabolic mold. The figure errors of the formed glass were measured and discussed in detail. It was found that the formed glass was not fully slumped at the edges, and should be trimmed to achieve better surface deviation. The root-mean-square (RMS) deviation and peak-valley (PV) deviation between formed glass and mold along the axial direction were 2.3 μm and 4.7 μm respectively.

• Journal of the Optical Society of Korea
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• 제20권1호
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• pp.101-106
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• 2016

A pupil filter is a useful technique for modifying the light intensity distribution near the focus of an optical system to realize depth of field (DOF) extension and superresolution. In this paper, we proposed a new design of the phase only pupil filter by using Zernike polynomials. The effect of design parameters of the new filters on DOF extension and superresolution are discussed, such as defocus Strehl ratio (S.R.), superresolution factor (G) and relative first side lobe intensity (M). In comparison with the other two types of pupil filters, the proposed filter presents its advantages on controlling both the axial and radial light intensity distribution. Finally, defocused imaging simulations are carried out to further demonstrate the effectiveness and superiority of the proposed pupil filter on DOF extension and superresolution in an optical imaging system.

• Journal of the Optical Society of Korea
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• 제18권4호
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• pp.341-344
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• 2014

This study proposes a modified sub-aperture stitching algorithm, which uses an image sharpening algorithm and particle swarm optimization to improve the stitching accuracy. In sub-aperture stitching interferometers with high positional accuracy, the high-frequency components of measurements are more important than the low-frequency components when compensating for position errors using a sub-aperture stitching algorithm. Thus we use image sharpening algorithms to strengthen the high-frequency components of measurements. When using image sharpening algorithms, sub-aperture stitching algorithms based on the least-squares method easily become trapped at locally optimal solutions. However, particle swarm optimization is less likely to become trapped at a locally optimal solution, thus we utilized this method to develop a more robust algorithm. The results of simulations showed that our algorithm compensated for position errors more effectively than the existing algorithm. An experimental comparison with full aperture-testing results demonstrated the validity of the new algorithm.