• The Journal of Internal Korean Medicine
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• v.19 no.1
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• pp.134-143
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• 1998

Background : The purpose of this study was to investigate the prodromal of cerebral infarction in attacked patients and to prove the traditional hypothesis that some symptoms were to be prodromes of cerebral infarction in the oriental medicine. Methods : The questionnaire which was based on symptoms of traditional hypothesis was distributed cerebral infarction patients who were confirmed by Brain CT or MRI.. Results : Fifty-six patients(93.3%) felt some symptoms within three years before onset. Most common prodromal symptoms was dizziness(50%), failure of memory(45%), numbness of arm(45%). Conclusion : This results suggest that the prodromal symptoms before cerebral infarction can be regarded as predicting sign. and we think that these research may contributed to preventing stroke and relapse.

• Korean Journal of Acupuncture
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• v.25 no.1
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• pp.197-211
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• 2008

Objectives : We studied on anti-allergic effects of Arctii Fructus Herbal Acupuncture(AFHA) and Arctii Fructus Herbal Acupuncture Solution(AF). Methods : In vivo, Animals were herbal-acupunctured AFHA at both ST36 three times for 5 days. Then, we investigated compound 48/80-induced active systemic anaphylaxis(ASA) using ICR mice and anti-DNP IgE-induced passive cutaneous anaphylaxis(PCA) using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase, IL-4 and TNF-a release from RBL-2H3 cells after treatment of AF of various concentrations. Results : In vivo, AFHA pretreatments at both ST36 inhibited compound 48/80-induced ASA. PCA was inhibited by AFHA pretreatments at both ST36. In vitro, AF treatments were not affect on cell viability and inhibited b-hexosaminidase, IL-4 and TNF-a release. Conclusions : These results suggest that AFHA and AF may be beneficial in the inhibition of allergic inflammatory response.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.22 no.11
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• pp.1049-1056
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• 2012

The forced vibration response characteristics of a cracked pipe conveying fluid with a concentrated mass are investigated in this paper. Based on the Euler-Bernoulli beam theory, the equation of motion is derived by using Hamilton's principle. The effects of concentrated mass and fluid velocity on the forced vibration characteristics of a cracked pipe conveying fluid are studied. The deflection response is the mid-span deflection of a cracked pipe conveying fluid. As fluid velocity and crack depth are increased, the resonance frequency of the system is decreased. This study will contribute to the decision of optimum fluid velocity and crack detection for the valve-pipe systems.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2009.04a
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• pp.238-238
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• 2009

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.10a
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• pp.631-633
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• 2018

국내 하수처리장의 수질기준이 강화되고 하수처리량이 지속적으로 증가하면서 하수처리장이 수용할 수 있는 처리용량의 한계와 이에 따른 관리 비용이 급격하게 증가하고 있다. 이러한 문제들을 개선하기 위한 다양한 방법들이 시도되고 있으나, 열악한 하수 환경과 높은 처리 비용 등으로 인하여 많은 어려움을 겪고 있는 것이 현실이다. 본 논문에서는 하수처리장으로 유입되는 하수를 오염도에 따라 하수량을 제어함으로서 하수처리장으로 유입되는 부하를 경감하여 하수 처리 비용을 줄이고, 환경 오염을 최소화 할 수 있는 친환경 하천 생태계 보존을 위한 IoT 기반 하수정보화 플랫폼을 제안하고자 한다.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.11
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• pp.1587-1591
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• 2015

For a higher definition discharge cell, the method of high speed addressing is necessary. In order to modify the surface charges, the liquefied $TiO_2$ or MgO powder is added on MgO layer in front glass and on the phosphor in rear glass in micro barrier discharge. Both the electro-optical properties and the discharge time lag characteristics are measured from 4 inch. test panel, such as the discharge voltage, current, luminance, luminous efficacy and discharge time lag. As the results, the statistic time lag is improved by about 40 %.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.1222-1223
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• 2007

This paper suggests a 6-pulse-shift converter with PWM current-source inverter based on buck-boost configuration to improve the efficiency and to reduce the switching frequency of inverter for photovoltaic generation system, the device can be operated as interface system between solar module system and power system grid without energy storage cell. the circuit has six current-source buck-boost converter which operate chopper part has one full bridge inverter which make a decision the polarity of AC output. Therefore, the proposed PWM power inverter has advantages such as the reduction of witching loss and realization of unity power factor operation. the theoretical backgrounds are discussed and the input-output characteristics for the implemented prototype inverter using TMS320F2812 are verified experimentally in this paper.

• Journal of IKEEE
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• v.23 no.3
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• pp.899-903
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• 2019

In networked control systems, time-varying delay of the transmitting signal is inevitable. If the transmission delay is longer than the fixed sampling time, the system will be unstable. To solve this problem, this paper proposes the method to predict the delay using logic-based fuzzy neural networks, and the predicted time delay will be used as a sampling time in the networked control systems. To verify the effectiveness of the proposed method, the delay data collected from the real system are used to train and test the logic-based fuzzy neural networks.

• Journal of Acupuncture Research
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• v.20 no.6
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• pp.128-139
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• 2003

Juglans sinensis Dode has been reported to have antioxidant activity. However, the effect of Juglans sinensis Dode aquacupuncture(JS) on reactive oxygen species(ROS)-induced alterations in membrane transport function in renal tubular cells. This study was performed to evaluate the effect of JS on the organic hydroperoxide t-butylhydroperoxide(tBHP)-induced inhibition of $Na^+$-dependent phosphate($Na^+$-Pi) uptake in opossum kidney (OK) cells, an established renal proximal epithelial cell line. tBHP inhibited $Na^+$-Pi uptake in a time-dependent manner. The inhibitory effect of tBHP was prevented by JS over concentration range of 0.05-1mg/100ml in a dose-dependent manner. Kinetic studies showed that tBHP caused an decrease in Vmax for $Na^+$-Pi uptake without any a significant change in Km. $Na^+$-dependent phosphonoformic acid binding, a irreversible inhibitor of renal $Na^+$-Pi uptake, was decreased by tBHP treatment. The reduction in Vmax and phosphonoformic acid binding by tBHP was prevented by JS. tBHP induced lipid peroxidation and its effect was completely inhibited by JS and antioxidant N,N'-diphenyl-p-phenylenediamine. These data suggest that the oxidant inhibits phosphate uptake by a reduction in the number of active carrier across the membrane. JS may prevent oxidant-induced inhibition of membrane transport function by a mechanism similar to antioxidants in renal epithelial cells. Although the precise constituents remain to be explored, JS may be employed as a useful candidate herb for drug development to prevent and treat oxidant-mediated renal failure.

• Journal of Acupuncture Research
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• v.21 no.2
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• pp.41-55
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• 2004

Objective : To investigate the possible molecular mechanism (s) of melittin as a candidate of anti-cancer drug, we examined the effects of the compound on the growth of human lung carcinoma cell line A549. Methods : Growth inhibitory study, flow cytometry analysis, SDS-polyacrylamide gel electrophoresis and Western blot analysis, RT-PCR and in vitro caspases activity assay were performed. Results : Melittin treatment declined the cell viability of A549 cells in a concentration-dependent manner, which was associated with induction of apoptotic cell death. Melittin treatment down-regulated the levels of Bcl-XS/L mRNA and protein expression of A549 cells, an anti-apoptotic gene, however, the those of Bax, a pro-apoptotic gene, were up-regulated. Melittin induced the proteolytic cleavage and activation of caspase-3 and caspase-9 protease in a dose-dependent manner without alteration of inhibitor of apoptosis proteins family and Akt expression. Western blot analysis and RT-PCR data revealed that the levels of tumor suppressor p53 and cyclin-dependent kinase inhibitor p21 were also remained unchanged. Conclusions : Taken together, these findings suggest that melittin-induced inhibition of human lung cancer cell growth is associated with the induction of apoptotic cell death via regulation of several major growth regulatory gene products, and melittin may have therapeutic potential in human lung cancer.