• 한국포장학회지
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• 제29권3호
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• pp.163-174
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• 2023

Though box compression strength (BCS) is commonly used as a performance criterion for shipping containers, estimating BCS remains a challenge. In this study, artificial neural networks (ANN) are implemented as a new tool, with a focus on building up ANN architectures for BCS estimation. An Artificial Neural Network (ANN) model can be constructed by adjusting four modeling factors: hidden neuron numbers, epochs, number of modeling cycles, and number of data points. The four factors interact with each other to influence model accuracy and can be optimized by minimizing model's Mean Squared Error (MSE). Using both data from the literature and "synthetic" data based on the McKee equation, we find that model estimation accuracy remains limited due to the uncertainty in both the input parameters and the ANN process itself. The population size to build an ANN model has been identified based on different data sets. This study provides a methodology guide for future research exploring the applicability of ANN to address problems and answer questions in the corrugated industry.

• 한국산학기술학회논문지
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• 제18권10호
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• pp.373-381
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• 2017

본 연구는 간호사의 심리적 안녕감에 영향을 주는 요인과 경로를 설명하는 이론적 모형을 구축하고, 검증하기 위해 실시되었다. 본 연구의 대상자는 B광역시와 G도에 소재한 200병상 이상의 4개 종합병원 병원에 근무 중인 간호사이며, 자료수집은 2017년 7월 3일부터 8월 25일까지 시행하였다. 간호사의 직무순환 스트레스의 경로계수를 검증한 결과, 직무순환 스트레스는 도전적 스트레스 평가, 방해적 스트레스 평가, 심리적 안녕감에 통계적으로 유의한 영향을 미치며, 방해적 스트레스 평가는 심리적 안녕감에 부의 영향을 미치는 것으로 나타났다. 간호사의 직무순환 스트레스는 도전적 스트레스 평가, 방해적 스트레스 평가, 심리적 안녕감에 직접 효과가 있었으며, 방해적 스트레스 평가는 심리적 안녕감에 직접 효과가 있는 것으로 나타났다. 또한 간호사의 직무순환 스트레스는 방해적 스트레스 평가를 매개로 심리적 안녕감에 간접효과가 있는 것으로 나타났다. 간호사는 직무순환을 경험하며 도전적인 스트레스와 방해적 스트레스를 갖는다는 것을 확인하였고, 특히 방해적인 스트레스는 간호사의 심리적 안녕을 떨어뜨리기 때문에 간호조직의 노력과 관리가 필요하다. 이에 간호조직은 간호사에게 직무 순환이 도전적 스트레스 요인이 될 수 있도록 긍정적인 조직 환경을 조성하고 체계적인 전략을 세워야 할 것이다.

• Toxicological Research
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• 제18권2호
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• pp.205-213
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• 2002

This study was undertaken to develop a subacute murine model for predicting occurrence of systemic anaphylaxis and to evaluate efficacy of various immunological parameters as the monitoring indices for the occurrence of anaphyalxis. The murine anaphyalxis model was developed through intraperitoneally sensitizing 100 $\mu\textrm{g}$ ovalbumin (OVA) in the presence of 1 mg alum and 300 ng cholera toxin twice a week interval followed by challenging 500 $\mu\textrm{g}$. OVA intravenously. Typical anaphylaxis symptoms were demonstrated at the both BALB/c mice, a strain prone to type-2 response, and C57BL/6 mice. a strain prone to type-1 response. Level of plasma histamine was approximately 50-fold or 30-fold higher in the mice sensitized with OVA than the mice sensitized with alum plus cholera toxin or the saline-treated mice after OVA challenge, respectively. Sensitization and challenge with OVA significantly enhanced plasma leukotriene $B_4$ level but not IgE levels in comparison with the control mice, which indicated the role of leukotriene $B_4$ for progression of anaphyalxis. Furthermore, among mice suffered from anaphylaxis, levels of OVA-specific IgGl were significantly higher in the BALB/c mice than in the C57BL/6 mice, which implied the genetic susceptibility for the induction of systemic anaphylaxis. Conclusively, simultaneous evaluation of histamine, leukotriene $B_4$, and allergen-specific IgG isotype may serve as more efficient monitoring tool for vaccine-related anaphyalxis.

• 동의생리병리학회지
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• 제37권2호
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• pp.25-29
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• 2023

This study was designed to establish an atopic dermatitis (AD) model using MC903 and was conducted to find out the optimal challenge concentration that can cause dermatitis symptoms enough to be experimentally verified while reducing adverse effects such as weight loss. MC903 was treated at concentrations of 2, 3, and 4 nmol/day, and evaluation of skin surface symptoms, water contents, histopathological changes, body weight changes, and spleen/body weight ratio was conducted. In addition, the expression level of thymic stromal lymphopoietin (TSLP) was also observed. In our results, MC903 induced AD skin lesions such as erythema, scab and fissure and lowered skin moisture level significantly. In addition, water holding capacities in the 3 or 4 nmol groups were diminished significantly compared to that in the control group. On the other hand, 4 nmol treatment induced a weight loss of up to 20% compared to control group. Finally, a higher level of TSLP expression was observed in the 3 nmol group than in the 2 nmol group or the 4 nmol group. Taken together, we propose a total 14-day protocol consisting of 3 days of sensitization (2 nmol/day) and 6 days of challenge (3 nmol/day).

• Asia Pacific Journal of Business Review
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• 제2권1호
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• pp.69-85
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• 2017

Electronic commerce (e-commerce) has seen as the potential to improve profitability and productivity in many areas as well as gaining notable attention in many countries. Despite, there has been some uncertainty about the e-commerce impacts for developing countries. The sufficient basic infrastructural deficiency, socio-political, economic and the lack of government public ICT policies have formed the significant barriers to the adoption and e-commerce growth in developing countries. Even though there are many researchers have found the common barriers to e-commerce in the developing nations, all business models targeting those countries are not equally successful. Small companies' persistence failed to challenge the e-commerce barriers in Cambodia because the firms didn't know the correct business model to succeed in this country online market. Therefore, this study will discuss the existing barriers which lead to limit e-commerce growth in Cambodia and the suggested solutions with the suitable business model for the e-commerce business in the country too.

• EDISON SW 활용 경진대회 논문집
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• 제4회(2015년)
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• pp.217-222
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• 2015

In this paper, a study was conducted for the optimization through shear web of shape the Edison program in wind power blade. We measured the displacement and stress distribution through two optimization methods to select the model with the smallest displacement and stress values. Before running the analysis, We try to find the inflection point through the shear web of the model and then analyze by introducing the geometric nonlinearity. The first optimization variables are introduced by the pitch angle and three web shapes. Third model such a honeycomb structure is good way to get an advantage for bending test. According to a method of previous optimization, third model is chosen and then the thickness of the web and blade as a variable is introduced, it is extracted as a result of displacement and the maximum stress per mass.

• EDISON SW 활용 경진대회 논문집
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• 제4회(2015년)
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• pp.500-509
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• 2015

This paper presents the single objective design optimization of plate-fin heat sink equipped with fan cooling system using Genetic Algorithm. The proper heat sink and fan model are selected based on the previous studies. And the thermal resistance of heat sinks and fan efficiency during operation are calculated according to specific design parameters. The objective function is combination of thermal resistance and fan efficiency which have been taken to measure the performance of the heat sink. And Decision making procedure is suggested considering life time of semiconductor and Fan Operating cost. And also Analytical Model used for optimization is validated by Fluent, Ansys 13.0 and this model give a quite reasonable and reliable design.

• 기술혁신학회지
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• 제8권2호
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• pp.832-859
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• 2005

Government-sponsored Research Institutes (GRIs) have made a great contribution to the development of Korea's Science and Technology (S&T). However, recently, GRIs are facing the challenge of many problems, for instance, absence of reasonable strategies, insufficient resources, and so on. Therefore, many GRIs are required for solving these problems by enhancing their strategic management capabilities. For this purpose, this paper suggests a Strategic Management Audit Model for Korean GRIs. The concept of Strategic Management Audit Model has not been widely adopted in Korean GRIs. In this paper, we suggest GRI-specific Strategic Management Model and apply it to Korea Basic Science Institute (KBSI), which is under the Korea Research Council of Fundamental Science and Technology (KRCF). Based on our strategic management audit, we propose several potential strategies for Korean Basic Research Institutes (KBSI). Our model and its implications will also be helpful for other Korean GRIs.

• ETRI Journal
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• 제32권4호
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• pp.634-637
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• 2010

This letter presents a model for a dynamic collaboration (DC) platform among cloud providers (CPs) that prevents adverse business impacts, cloud vendor lock-in and violation of service level agreements with consumers, and also offers collaborative cloud services to consumers. We consider two major challenges. The first challenge is to find an appropriate market model in order to enable the DC platform. The second is to select suitable collaborative partners to provide services. We propose a novel combinatorial auction-based cloud market model that enables a DC platform among CPs. We also propose a new promising multi-objective optimization model to quantitatively evaluate the partners. Simulation experiments were conducted to verify both of the proposed models.

• EDISON SW 활용 경진대회 논문집
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• 제5회(2016년)
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• pp.368-372
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• 2016

In this paper, the physics-based analytical model of transition metal dichalcogenide (TMD)-based double-gate (DG) tunneling field-effect transistors (TFETs) is proposed. The proposed model is derived by using the two-dimensional (2-D) Landauer formula and the Wentzel-Kramers-Brillouin (WKB) approximation. For improving the accuracy, nonlinear and continuous lateral energy band profile is applied to the model. 2-D density of states (DOS) and two-band effective Hamiltonian for TMD materials are also used in order to consider the 2-D nature of TMD-based TFETs. The model is validated by using the tight-binding non-equilibrium Green's function (NEGF)-based quantum transport simulation in the case of monolayer molybdenum disulfide ($MoS_2$)-based TFETs.