• Title/Summary/Keyword: Challenge Model

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Recent Trends and Characteristics of International Arbitration in Latin American Countries (라틴아메리카 국제중재의 최근 발전경향과 특징)

  • Jo, Hee-Moon
    • Journal of Arbitration Studies
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    • v.18 no.1
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    • pp.97-119
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    • 2008
  • The reluctance of Latin American countries to practice international arbitration is not a new topic in international law. This reluctance historically based on Calvo Doctrine provoked not only the absence of Latin American countries from the major international commercial arbitration conventions, but obsolete national arbitration legislation. Recently, however, these countries have undertaken major steps showing that the region is no longer reluctant to practice international commercial arbitration. Most Latin American countries have ratified the 1958 Convention on the Recognition and Enforcement of Foreign Arbitral Awards ("New York Convention"), the 1965 Convention on the Settlement of Investment Disputes ("Washington Convention") and the 1975 Inter-American Convention on International Commercial Arbitration ("Panama Convention"). The majority of Latin American countries have also modified and adapted their national legislation on arbitration to the UNCITRAL model law. Even judiciary has been following this pro-arbitration. This article will focus on some of these factors provoking the acceptance of international commercial arbitration in Latin America to trace the common trends and characteristics in an attempt to understand better how international arbitration set on its place firmly. For this purpose we selected five countries, Brazil, Argentina, Chile, Mexico and Venezuela, to analyse legislations and jurisprudence. Latin America is ready to challenge any obstacles to promote arbitration as alternative methods of judicial resolution. There is an ever-increasing number of international arbitration in Latin America. Both practitioners and judiciary have shown desires to promote the resolution of disputes by arbitration and used the legal instruments to ensure that process interpreting and applying legislations for pro-arbitration. Even there remains Calvo Doctrine's culture in Latin America still now, it should be certain this culture will disappear from the conduct of international arbitration.

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Effect of Online Social Network to build virtual Human Capital (온라인 모임이 사회적 자원 형성에 미치는 영향)

  • Yun, Ho-Seong;Park, Jung-Hee;Lee, Ki-Dong
    • Journal of Digital Convergence
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    • v.8 no.1
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    • pp.71-79
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    • 2010
  • Impact of online social network to cyber community has increased much attention recently. The biggest challenge in fostering a social network is to the extent whether it helps to build human capital network or social community. We propose what critical factors influence the formation of online capital network. The study uses three independent factors as motivation, self disclosure, and interactivity and two dependent factors as knowledge sharing and strengthening relationships to create virtual capital connection. Data collected from 256 university students to test the proposed model. The results of the study shows that all hypothesis are supported except one with strengthening relationship. Implications and limitations of this research are discussed.

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Effect of Lipofectin on Antigen-presenting Function and Anti-tumor Activity of Dendritic Cells (수지상세포의 항원제시 능력 및 항암활성에 미치는 Lipofectin의 영향)

  • Noh, Young-Woock;Lim, Jong-Seok
    • IMMUNE NETWORK
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    • v.6 no.2
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    • pp.102-110
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    • 2006
  • Background: Dendritic cells (DC) are professional antigen-presenting cells in the immune system and can induce T cell response against virus infections, microbial pathogens, and tumors. Therefore, immunization using DC loaded with tumor-associated antigens (TAAs) is a powerful method of inducing anti-tumor immunity. For induction of effective anti-tumor immunity, antigens should be efficiently introduced into DC and presented on MHC class I molecules at high levels to activate antigen-specific $CD8^+$ T cells. We have been exploring methods for loading exogenous antigens into APC with high efficiency of Ag presentation. In this study, we tested the effect of the cationic liposome (Lipofectin) for transferring and loading exogenous model antigen (OVA protein) into BM-DC. Methods: Bone marrow-derived DC (EM-DC) were incubated with OVA-Lipofectin complexes and then co-cultured with B3Z cells. B3Z activation, which is expressed as the amount of ${\beta}$-galactosidase induced by TCR stimulation, was determined by an enzymatic assay using ${\beta}$-gal assay system. C57BL/6 mice were immunized with OVA-pulsed DC to monitor the in vivo vaccination effect. After vaccination, mice were inoculated with EG7-OVA tumor cells. Results: BM-DC pulsed with OVA-Lipofectin complexes showed more efficient presentation of OVA-peptide on MHC class I molecules than soluble OVA-pulsed DC. OVA-Lipofectin complexes-pulsed DC pretreated with an inhibitor of MHC class I-mediated antigen presentation, brefeldin A, showed reduced ability in presenting OVA peptide on their surface MHC class I molecules. Finally, immunization of OVA-Lipofectin complexes-pulsed DC protected mice against subsequent tumor challenge. Conclusion: Our data provide evidence that antigen-loading into DC using Lipofectin can promote MHC class I- restricted antigen presentation. Therefore, antigen-loading into DC using Lipofectin can be one of several useful tools for achieving efficient induction of antigen-specific immunity in DC-based immunotherapy.

Implementation of PLM Functional and Architecture between ETO Shipbuilding and ATO Industries (주문형 설계 조선산업과 주문형 조립산업의 특성에 따른 PLM 기능과 구조 설계)

  • Kim, Seung-Hyun;Jeon, Jung-Ik;Lee, Jang-Hyun;Lee, Won-Joon
    • Korean Journal of Computational Design and Engineering
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    • v.15 no.6
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    • pp.425-439
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    • 2010
  • The current challenge with which most shipyards are forced is to reduce the design time and the time-to-delivery because of explosive order of shipbuilding. Collaborative design and product data management have become important to reduce the lead time. Furthermore, enterprise information technologies such as ERP (Enterprise Resource Planning), SCM (Supply Chain management), and APS (Advanced Planning System) requires the collaborative environment. Also, manufacturing environment has been considered as a topic of strategic interest to get shorter product lifecycles in shipyards. Most shipyards have chosen an environment of ETO (Engineering To Order) strategy which designs and produces new products in response to various requirements of customer, rules and regulations. In the ATO (Assemble 10 Order) environment, most component parts have been designed to be procured or produced on the order requirement. The basic distinction between the ETO and ATO is the timing of the design. Thus in the ATO environment, it is more flexible in reducing the lead time to meet the specified requirements of customers. However, the ETO strategy requires new ship design process and ship product structures that are linked with the implementation of PLM. And, the function and architecture of current PLM solution has been designed based upon ATO environment properly. This paper presents the PLM architecture which effectively reflects the characteristics of shipbuilding. 4-layer architecture model is suggested to implement the PLM system. Also, implemented functions of ship PLM is explained in order to make a practical guidance for ship PLM implementation.

The Challenge of the Third Generation Port and Port Competition (제 3 세대 항만의 도래와 항만경쟁)

  • 문성혁
    • Journal of the Korean Institute of Navigation
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    • v.18 no.2
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    • pp.91-109
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    • 1994
  • Technological and organisational changes in transport system have introduced new dimension into port system development and inter-port competition. The quality of service now required by the customer is costly and not easily provided by small shipping companies and small ports. It has been suggested that in the future container shipping may be concentrated by space-sharing arrangements or actual mergers into the hands of a few mega-operators with the investment potential to provide total logistics networks. In order to compete effectively, high load factors will be essential and port concentration inevitable. A fa-voured few ports will become the load centres and other ports will assume a secondary feeder role. In this study, three questions are raised and attempts are made to answer them : (a) what is the new role of ports today ; (b) why should ports be engaged in this new role ; and (c) how can ports play this new role. In short, a modern port should be a service centre and a logistic platform for international trade and transport-a third generation port. Ports, in particular, have to make every effort to be competitive in the cost and quality of services and to make the port a transport and distribution service centre. For most ports, this is not an option but a must ; an essential requirement for survival in this win or lose situation. The best way to win is to maintain a close contact with port users, listen to them, discuss with them, help them and satisfy them. That is port marketing. Starting from the findings of port marketing, it is es-sential to work out appropriate development plans and marketing targets and to improve port competitive-ness. As an alternative method, a port competitiveness model is suggested, which may help port managers to make appropriate improvements.

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An overview of applicability of WEQ, RWEQ, and WEPS models for prediction of wind erosion in lands

  • Seo, Il Whan;Lim, Chul Soon;Yang, Jae Eui;Lee, Sang Pil;Lee, Dong Sung;Jung, Hyun Gyu;Lee, Kyo Suk;Chung, Doug Young
    • Korean Journal of Agricultural Science
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    • v.47 no.2
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    • pp.381-394
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    • 2020
  • Accelerated soil wind erosion still remains to date to cause severe economic and environmental impacts. Revised and updated models to quantitatively evaluate wind induced soil erosion have been made for specific factors in the wind erosion equation (WEQ) framework. Because of increasing quantities of accumulated data, the WEQ, the revised wind erosion equation (RWEQ), the wind erosion prediction system (WEPS), and other soil wind erosion models have been established. These soil wind erosion models provide essential knowledge about where and when wind erosion occurs although naturally, they are less accurate than the field-scale. The WEQ was a good empirical model for comparing the effects of various management practices on potential erosion before the RWEQ and the WEPS showed more realistic estimates of erosion using easily measured local soil and climatic variables as inputs. The significant relationship between the observed and predicted transport capacity and soil loss makes the RWEQ a suitable tool for a large scale prediction of the wind erosion potential. WEPS developed to replace the empirical WEQ can calculate soil loss on a daily basis, provide capability to handle nonuniform areas, and obtain predictions for specific areas of interest. However, the challenge of precisely estimating wind erosion at a specific regional scale still remains to date.

Hierarchical Power Management Architecture and Optimal Local Control Policy for Energy Efficient Networks

  • Wei, Yifei;Wang, Xiaojun;Fialho, Leonardo;Bruschi, Roberto;Ormond, Olga;Collier, Martin
    • Journal of Communications and Networks
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    • v.18 no.4
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    • pp.540-550
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    • 2016
  • Since energy efficiency has become a significant concern for network infrastructure, next-generation network devices are expected to have embedded advanced power management capabilities. However, how to effectively exploit the green capabilities is still a big challenge, especially given the high heterogeneity of devices and their internal architectures. In this paper, we introduce a hierarchical power management architecture (HPMA) which represents physical components whose power can be monitored and controlled at various levels of a device as entities. We use energy aware state (EAS) as the power management setting mode of each device entity. The power policy controller is capable of getting information on how many EASes of the entity are manageable inside a device, and setting a certain EAS configuration for the entity. We propose the optimal local control policy which aims to minimize the router power consumption while meeting the performance constraints. A first-order Markov chain is used to model the statistical features of the network traffic load. The dynamic EAS configuration problem is formulated as a Markov decision process and solved using a dynamic programming algorithm. In addition, we demonstrate a reference implementation of the HPMA and EAS concept in a NetFPGA frequency scaled router which has the ability of toggling among five operating frequency options and/or turning off unused Ethernet ports.

An Extended Modal Warping Approach to Real-Time Simulation of Thin Shells (얇은 쉘의 실시간 시뮬레이션을 위한 모달 와핑 기법의 확장)

  • Choi, Min-Gyu;Woo, Seung-Yong;Ko, Hyeong-Seok
    • Journal of Korea Game Society
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    • v.7 no.2
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    • pp.11-20
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    • 2007
  • This paper proposes a real-time simulation technique for thin shells undergoing large deformation. Shells are thin objects such as leaves and papers that can be abstracted as 2D structures. Development of a satisfactory physical model that runs in real-time but produces visually convincing animation of thin shells has been remaining a challenge in computer graphics. Rather than resorting to shell theory which involves the most complex formulations in continuum mechanics, we adopt the energy functions from the discrete shells proposed by Grinspun et al. For real-time integration of the governing equation, we develop a modal warping technique for shells. This new simulation framework results from making extensions to the original modal warping technique which was developed for the simulation of 3D solids. We report experimental results, which show that the proposed method runs in real-time even for large meshes, and that it can simulate large bending and/or twisting deformations with acceptable realism.

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Induced systemic resistance and plant growth promotion of a phosphate-solubilizing bacterium, Enterobactor intermedium 60-2G (인산가용미생물, Enterobacterium intermedium 60-2G의 식물 생장 촉진 및 전신저항성 유도)

  • Kim, Young-Cheol;Kim, Chul-Hong;Kim, Kil-Young;Cho, Baik-Ho
    • Korean Journal of Soil Science and Fertilizer
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    • v.35 no.4
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    • pp.223-231
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    • 2002
  • A phosphate-solubilizing bacterium, Enterobacter intermedium 60-2G, was examined for plant growth-promotion and induction of systemic resistance using a model system of cucumber and scab disease, caused by Cladosporium cucumerinum. Compared with a nonbacterized control, treatment of cucumber with E. intermedium significantly reduced the severity of scab disease after challenge-inoculation with C. cucumerinum. Treatment of cucumber with E. intermedium also enhanced cucumber growth. The 60-2G strain showed a strong antimicrobial activity against several plant pathogenic fungi including Fusarium soysporum and Magnaporthe grisea. These results suggest the E. intermedium 60-2G is a promising candidate as a biological control agent displaying multiple beneficial properties to promote plant health.

Lutein Modulates Th2 Immune Response in Ovalbumin-Induced Airway Inflammation (Ovalbumin으로 유도한 천식 생쥐모델에서 lutein의 Th2 면역반응 연구)

  • Song, Jun-Young;Lee, Chang-Min;Lee, Min-Ki
    • Journal of Life Science
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    • v.22 no.3
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    • pp.298-305
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    • 2012
  • The general term flavonoids is often used to categorize a family of natural compounds that are highly abundant in all higher plants, and which in recent years have attracted scientific interest as therapeutics. Lutein is a xanthophyll and one of 600 known naturally occurring carotenoids. It is found in green vegetables such as spinach and kale, and has been demonstrated to exert anti-inflammatory activities. However, its anti-allergic effect in the Th1/Th2 immune response is poorly understood. In this study, we attempt to determine whether lutein regulates inflammatory mediators in an ovalbumin (OVA)-induced murine asthma model. To address this, mice were sensitized and challenged with OVA, and then treated with lutein before the last OVA challenge. Administration of lutein significantly suppressed the OVA-induced airway hyper-responsiveness. It also resulted in a significant alleviation of the infiltration of inflammatory cells into the bronchoalveolar lavage. Additionally, lutein attenuated the increased expression of Th2 responses in OVA-challenged mice. These results demonstrate that lutein is a potent inhibitor that reduces Th2 immune responses. Furthermore, they show that the immunopharmacological function is mediated by a pathway that involves and is regulated by Th2 immune response.