• Journal of Industrial Convergence
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• v.21 no.5
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• pp.43-50
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• 2023

The South Korean government announced its plan to pursue membership in the CPTPP in 2022, aiming to establish a stable supply chain within the Asia-Pacific region. The CPTPP, led by Japan, was ratified in 2018 by 11 countries with the goal of eliminating tariffs and establishing new trade rules. According to our analysis, since the implementation of the CPTPP, there has been a trade promotion effect among Japan and member countries, with greater effects observed in countries with higher GDP per capita and closer geographical distance. As long as tariff elimination and reduction proceed as planned, the trade promotion effects are expected to expand gradually. However, the expansion of trade between Japan and CPTPP member countries may also indicate a relative contraction in trade with non-member countries, potentially posing a threat to the stable supply chain in the Korean industry within the Asia-Pacific region. As Japan is Korea's fourth-largest trading partner, it is necessary to carefully consider the impact of CPTPP on Japan's future trade with member countries and engage in discussions regarding Korea's participation and negotiation content based on a thorough examination of the matter.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.23 no.2
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• pp.31-38
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• 2023

Maple syrup urine disease (MSUD) is an autosomal recessive metabolic disorder caused by a deficiency in branched chain α-keto acid dehydrogenase (BCKAD). Between 1997, when Korea's MSUD case was first reported, and 2023, 14 cases were reported in the literature. 29% of the cases experienced developmental delay, and 29% expired. The prevalence of MSUD in Korea was estimated to be 1 in 230,000. Of 21 MSUD patients currently being treated at the Korea Genetics Research Center, 19 were detected through newborn screening program, and 2 were diagnosed by the symptoms. 14 MSUD patients had confirmed genetic mutations; 6 (43%) were BCKDHA and 8 (57%) were BCKDHB. In one case, a large deletion was observed. 4 patients had leucine levels above 2,000 (umo/L), and post-dialysis diet therapy was initiated in the newborn period. No patient required further dialysis as diet therapy and regular monitoring proved highly effective. Most MSUD patients were growing normally; weight and height growth were above the 50th percentile in 76% of the cases while BMI values were higher than normal in 71% of cases. Developmental delays were observed only in 2 cases (10%) and anticonvulsant use in 3 cases (14%). With newborn screening available to all Korean infants, early diagnosis and intervention should allow most patients to remain asymptomatic. However, ongoing surveillance, dietary management and continued patient compliance as well as rapid correction of acute metabolic decompensations remain critical to a favorable long-term prognosis.

• Korean Journal of Food Science and Technology
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• v.48 no.2
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• pp.128-132
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• 2016

In this study, polyethylene glycol (PEG) was used to improve DNA amplification efficiency during whole genome amplification (WGA). Amplification efficiency was determined by adding PEG with different molecular weights to the WGA reaction. The greatest increase in amplification efficiency was obtained with PEG 4,000 used at 1.5% concentration. Foodborne pathogenic DNA was amplified by WGA and quantitatively analyzed by real-time polymerase chain reaction. DNA of Salmonella serotype Typhimurium, Listeria monocytogenes, and Vibrio parahaemolyticus was amplified 7,777.01, 9,981.22, and 1,239.03 fold, respectively, by WGA. On adding PEG in the WGA reaction (i.e., enhanced WGA [eWGA]), 18-40-fold more DNA amplification was achieved. Thus, these analyses showed that foodborne pathogens, which are usually present at very low concentration in foods, can be detected by real-time PCR and WGA.

• Microbiology and Biotechnology Letters
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• v.51 no.3
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• pp.268-279
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• 2023

The pharmaceutical industry in Bangladesh produces a diverse range of antibiotics for human and animal use, however, waste disposal management is inadequate. This results in substantial quantities of antibiotics being discharged into water bodies, which provide suitable environment for the growth of antibiotic-resistant bacteria, capable of spreading resistance genes. This study intended for exploring the bacterial antibiotic resistance profile in adjoining aquatic environmental sources of pharmaceutical manufacturing facilities in Bangladesh. Seven surface water samples were collected from the vicinity of two pharmaceutical industries located in the Savar area and 51 Escherichia coli isolates were identified using both phenotypic and genotypic methods. Antibiotic susceptibility tests revealed the highest percentage of resistance against ampicillin, azithromycin, and nalidixic acid (100%) and the lowest resistance against meropenem (1.96%) out of sixteen different antibiotics tested. 100% of the study E. coli isolates were observed with Multidrug resistance phenotypes, with the Multiple Antibiotic Resistance (MAR) value ranging from 0.6-1.0. Furthermore, 69% of the isolates were Extended Spectrum Beta-Lactamases (ESBL) positive as per the Double Disk Diffusion Synergy Test (DDST). ESBL resistance genes bla_TEM, bla_CTX-M-13, bla_CTX-M-15, and bla_SHV were detected in 70.6% (n = 36), 60.8% (n = 32), 54.9% (n = 28), and 1.96% (n = 1) of the isolates, respectively, by Polymerase Chain Reaction (PCR). Additionally, 15.68% (n = 8) of the isolates were positive for E. coli specific virulence genes in PCR. These findings suggest that pharmaceutical wastewater, if not properly treated, could be a formidable source of antibiotic resistance spread in the surrounding aquatic environment. Therefore, continued surveillance for drug resistance among bacterial populations around drug manufacturing facilities in Bangladesh is necessary, along with proper waste disposal management.

• Management & Information Systems Review
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• v.38 no.1
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• pp.83-101
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• 2019

Blockchain is considered as an innovative technology along with Artificial Intelligence, Big Data, and Internet of Things. However, since the inception of the genesis of blockchain technology, the cryptocurrency Bitcoin, the technology is not utilized widely, not let alone disruptive applications. Most of the blockchain research deals with the cryptocurrency, general descriptions of the technology such as trend, outlook of the technology, explanation of component technology, and so on. There are no killer applications like Facebook or Google, of course. Reflecting on the slow adoption by businesses, we wanted know about the current status of the research on blockchain in Korea. The main purpose of this paper is to help business practitioners to identify the application of blockchain to enhance the competitiveness of their organization. To do that, we first use the framework by Iansiti et al (2017) and categorize the blockchain related articles published in Korea according to the framework. This is to provide a benchmark or cases of other organizations' adoption of blockchain technology. Second, based on the value proposition of blockchain applications, we suggest evolutionary paths for adopting them. Third, from the demand pull perspective of technology adoption for innovation, we propose applicable areas where blockchain applications can be introduced. Fourth, we use the value chain model to find out the appropriate domains of blockchain applications in the corporate value chains. And the five competitive forces models is adopted to find ways of lowering the power of forces by incorporating blockchain technology.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.14 no.3
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• pp.201-207
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• 2021

Deep learning, a type of machine learning, performs learning while changing the weights as it progresses through each learning process. Tensor Flow and Keras provide the results of the end of the learning in graph form. Thus, If an error occurs, the result must be discarded. Consequently, existing technologies provide a function to roll back learning results, but the rollback function is limited to results up to five times. Moreover, they applied the concept of MLOps to track the deep learning process, but no rollback capability is provided. In this paper, we construct a system that manages the intermediate value of the learning process by blockchain to record the intermediate learning process and can rollback in the event of an error. To perform the functions of blockchain, the deep learning process and the rollback of learning results are designed to work by writing Smart Contracts. Performance evaluation shows that, when evaluating the rollback function of the existing deep learning method, the proposed method has a 100% recovery rate, compared to the existing technique, which reduces the recovery rate after 6 times, down to 10% when 50 times. In addition, when using Smart Contract in Ethereum blockchain, it is confirmed that 1.57 million won is continuously consumed per block creation.

• Asia pacific journal of information systems
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• v.24 no.1
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• pp.1-29
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• 2014

To provide a fundamental understanding on the inherent relationship between IT capabilities and sustainable firm heterogeneity, we investigate the dual roles that institutional pressures play, namely, as antecedents of IT capabilities and as moderator of the relationship between IT capabilities and IT innovation success, where IT innovation success plays a mediating role between IT capabilities and firm performance. The structural model was tested, and the results of the PLS analysis provided general support for the proposed hypotheses. IT capabilities had an indirect effect mediated by IT innovation success on firm performance. With IT activities assumed to be embedded in the institutional context, the dual roles of institutional pressures are verified. This study contributes to the literature on IT capabilities by considering both the determining role of institutional pressures on IT capabilities and the institutional context of the chain that connects IT capabilities to firm performance. The results suggest that a firm not only manages various institutional pressures to foster its IT capabilities but also adapts to different contexts with a certain level of institutional pressures to facilitate its IT capabilities and outperform its competitors, which could be sustained through IT innovation success.

• Journal of Information Technology Services
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• v.15 no.1
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• pp.1-18
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• 2016

Recently, in the bio-field success stories of ventures through a biosimilar technology is being excavated. but the growth of ICT industry has been stagnant since reaching a boom in the dissemination of early high-speed internet in 2000s. The purpose of this study is to explore the factors of change of business model and business strategy of ICT ventures and SMEs with the evolution of the digital ecosystem, and to drive the factors to be competitive on the global value chain. The researcher selected an entreprenuership, market-innovation orientation, technology-innovation orientation, and Administration-innovation orientation as internal factors influencing the global competence and healthiness of the ecosystem as external factors. The researcher applied samples of 94 ICT Venture and SMEs to a research model, and adopted 5 hypotheses. The researcher believes that only a few hypotheses were adopted because it takes time for overall innovation orientation of ICT Venture and SMEs to result in the real global competence as the their innovation orientation is still on the level of domestic market. And the researcher also thinks that only healthiness of the ecosystem affected management performances because the companies' performances of the last 3 years were so weak that the correlation between innovation orientation of each company and the performances were not big enough.

• Fisheries and Aquatic Sciences
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• v.16 no.2
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• pp.93-99
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• 2013

In 2009, a systemic megalocytivirus infection associated with high mortality was detected for the first time in cultured starry flounder Platichthys stellatus in Korea. Diseased starry flounder had pale bodies and gill coloring and enlarged spleens. Histopathological examinations revealed basophilic enlarged cells in various organs of diseased starry flounder. Polymerase chain reaction (PCR) was performed on tissue samples using three published primer sets developed for the red sea bream iridovirus. PCR products were detected for all primer sets, except 1-F/1-R, which are registered by the World Organization for Animal Health (OIE). The part of the gene corresponding to the full open reading frame encoding the viral major capsid protein (MCP) was amplified by PCR. PCR products of approximately 1,581 bp were cloned, and the nucleotide sequences were analyzed phylogenetically. The MCP gene of the starry flounder iridovirus, designated SFIV0909, was identical to that of the turbot reddish body iridovirus (AB166788).

• Korea Trade Review
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• v.46 no.1
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• pp.59-81
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• 2021

This paper aims to analyze Korea's trade and investment performance in Spain and the business environment of Spain, and to find efficient strategies for entering into the Spanish market. This study is organized into five chapters. To begin with, it explains an overview of the Spanish economy and the current status of its major industries. Then, it analyzes Korea's trade and investment performance in Spain, the structure of comparative advantage and the trade trends of major import and export items, since 2011 when the Korea-EU FTA went into effect. Lastly, based on the results of this analysis, Korea's strategies for entering into the Spanish market are derived. The strategies derived from the analysis are as follows: (1) entering startups in the Spanish market through CVC cooperation and participation in large tech forums, (2) linking the Spanish interest in K-Culture to consumer goods exports, (3) promoting cooperation in the IT industry in response to the Spanish government's 'Connected Industry 4.0', (4) building a new Korean-Spanish value chain in response to the mobility revolution, (5) advancing jointly into a third country by combining the strengths of both Korea and Spain, (6) cooperating with the Spanish government to establish a sustainable energy policy, (7) promoting jointly with the Spanish government through smart city strategies and project exchanges, and (8) building a European logistics hub in Spain in preparation for post-Brexit.