• Clinical and Experimental Reproductive Medicine
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• 제45권1호
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• pp.48-51
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• 2018

We report the case of a 46-year-old Chinese male patient who visited our clinic complaining of infertility. Semen analysis revealed azoospermia, and azoospermia factor c region partial deletion (b1/b3) was detected using Y chromosome microdeletion analysis. Testicular sperm extraction was performed after genetic counseling. The bilateral ductus deferens and a portion of the epididymis were absent, whereas the remaining epididymis was expanded. Motile intratesticular spermatozoa were successfully extracted from the seminiferous tubule. On histopathology, nearly complete spermatogenesis was confirmed in almost every seminiferous tubule. To our knowledge, this is the first case report of b1/b3 deletion with a congenital bilateral absence of the vas deferens and almost normal spermatogenesis.

• Clinical and Experimental Reproductive Medicine
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• 제45권1호
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• pp.44-47
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• 2018

Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.

• Clinical Endoscopy
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• 제56권3호
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• pp.353-366
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• 2023

Background/Aims: This study aimed to clarify the efficacy and safety of pancreatic duct lavage cytology combined with a cell-block method (PLC-CB) for possible pancreatic ductal adenocarcinomas (PDACs). Methods: This study included 41 patients with suspected PDACs who underwent PLC-CB mainly because they were unfit for undergoing endoscopic ultrasonography-guided fine needle aspiration. A 6-Fr double lumen catheter was mainly used to perform PLC-CB. Final diagnoses were obtained from the findings of resected specimens or clinical outcomes during surveillance after PLC-CB. Results: Histocytological evaluations using PLC-CB were performed in 87.8% (36/41) of the patients. For 31 of the 36 patients, final diagnoses (invasive PDAC, 12; pancreatic carcinoma in situ, 5; benignancy, 14) were made, and the remaining five patients were excluded due to lack of surveillance periods after PLC-CB. For 31 patients, the sensitivity, specificity, and accuracy of PLC-CB for detecting malignancy were 94.1%, 100%, and 96.8%, respectively. In addition, they were 87.5%, 100%, and 94.1%, respectively, in 17 patients without pancreatic masses detectable using endoscopic ultrasonography. Four patients developed postprocedural pancreatitis, which improved with conservative therapy. Conclusions: PLC-CB has an excellent ability to detect malignancies in patients with possible PDACs, including pancreatic carcinoma in situ.

• Clinical Endoscopy
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• 제56권4호
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• pp.510-520
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• 2023

Background/Aims: We aimed to investigate (1) promising clinical findings for the recognition of focal type autoimmune pancreatitis (FAIP) and (2) the impact of endoscopic ultrasound (EUS)-guided tissue acquisition (EUS-TA) on the diagnosis of FAIP. Methods: Twenty-three patients with FAIP were involved in this study, and 44 patients with resected pancreatic ductal adenocarcinoma (PDAC) were included in the control group. Results: (1) Multivariate analysis revealed that homogeneous delayed enhancement on contrast-enhanced computed tomography was a significant factor indicative of FAIP compared to PDAC (90% vs. 7%, p=0.015). (2) For 13 of 17 FAIP patients (76.5%) who underwent EUS-TA, EUS-TA aided the diagnostic confirmation of AIPs, and only one patient (5.9%) was found to have AIP after surgery. On the other hand, of the six patients who did not undergo EUS-TA, three (50.0%) underwent surgery for pancreatic lesions. Conclusions: Homogeneous delayed enhancement on contrast-enhanced computed tomography was the most useful clinical factor for discriminating FAIPs from PDACs. EUS-TA is mandatory for diagnostic confirmation of FAIP lesions and can contribute to a reduction in the rate of unnecessary surgery for patients with FAIP.

• 한국디지털건축인테리어학회논문집
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• 제4권2호
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• pp.35-43
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• 2004

Transformations of the urban spatial structure, from sub-area redevelopment to newtown development, results great influences upon existing urban condition and spatial configuration. The purpose of the study is to analyse the effect of the urban spatial configuration of Uijongbu city where experienced changes after newly development of city center and new residential area. The west part of the city where is limited in growth by military bases, ego U.S Army basecamp, were planned and established as the other axis of the city center since mid 1980's. After that new residential area which is located in far east of the city were also developed. Space syntax as a methodology has been adopted to conduct quantitative analysis which is able to interpret differences between sub-areas ; old city center, new city center, new residential area. The results of the analysis are follows ; 1) existing structure of the urban fabric, especially old city center, is sustained and intensified, 2) new city center which is west part of the city has failed to achieve organic spatial connection adjacent to old city center, 3) there is less spatial depecdency relationship between city center and new residential area where is identified as another small self-support city within the city.

• 한국경제지리학회지
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• 제22권3호
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• pp.366-379
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• 2019

이 연구의 목적은 최고지가에 대한 비율로 도심의 경계를 설정하는 방법을 검토하고 원도심과 신도심의 특성 및 영향력을 파악하는 것이다. 이를 위해 부산시를 대상으로 2000년과 2015년의 표준지공시지가를 활용하여 도심 경계를 설정하고 원도심과 신도심의 지가 변화를 비교 분석하였다. 주요 연구 결과는 다음과 같다. 첫째, 최고지가에 대한 비율 8%와 10%를 적용해보았을 때 기존 연구의 도심 경계보다 도심의 범위가 넓게 추정되었다. 최고지가에 대한 비율로 도심의 경계를 설정하는 방법은 시간의 흐름 또는 각 도시의 사회적, 경제적 상황에 따라 달라지므로 신중하게 접근하여야 한다. 둘째, 도심의 지가가 주변지역까지 미치는 파급력은 원도심이 강한 것으로 나타났다. 하지만 최고지가지점(PLVI)이 신도심으로 이전되었을 뿐만 아니라 신도심의 지가가 많이 상승한 점으로 미루어 볼 때 앞으로 부산시의 신도심 지역이 더욱 성장할 것으로 예측된다.

• Clinical Endoscopy
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• 제57권5호
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• pp.647-655
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• 2024

Background/Aims: Endoscopic biliary drainage using self-expandable metallic stents (SEMSs) for malignant biliary strictures occasionally induces acute cholecystitis (AC). This study evaluated the efficacy of prophylactic gallbladder stents (GBS) during SEMS placement. Methods: Among 158 patients who underwent SEMS placement for malignant biliary strictures between January 2018 and March 2023, 30 patients who attempted to undergo prophylactic GBS placement before SEMS placement were included. Results: Technical success was achieved in 21 cases (70.0%). The mean diameter of the cystic duct was more significant in the successful cases (6.5 mm vs. 3.7 mm, p<0.05). Adverse events occurred for 7 patients (23.3%: acute pancreatitis in 7; non-obstructive cholangitis in 1; perforation of the cystic duct in 1 with an overlap), all of which improved with conservative treatment. No patients developed AC when the GBS placement was successful, whereas 25 of the 128 patients (19.5%) without a prophylactic GBS developed AC during the median follow-up period of 357 days (p=0.043). In the multivariable analysis, GBS placement was a significant factor in preventing AC (hazard ratio, 0.61; 95% confidence interval, 0.37-0.99; p=0.045). Conclusions: GBS may contribute to the prevention of AC after SEMS placement for malignant biliary strictures.

• 한국실내디자인학회논문집
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• 제40호
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• pp.102-108
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• 2003

Currently, there is no facility standard for a city public health center. The facility standard of rural public health center is referred to architectural plan of city public health center. This study is about architectural plan of the city public health center and have been in 7 public health centers in Daegu investigated. Conclusions can be summarized as follows: 1) The Mother and child hygienic section, area ratio which is presented by the facility standard of rural public health center must be increased in case of city public health center since function-reinforcement of the mother and child hygienic section is required. 2) Business section, the area ratio which is presented by the facility standard of rural public health center must be diminished for city public health center because it has been excessively allocated.

• 한국전자통신학회논문지
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• 제2권3호
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• pp.191-198
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• 2007

u-City에서 도시기능과 관리의 효율화를 위해 기존 정보화 인프라를 혁신시키고 도시 내에 발생하는 모든 업무를 실시간으로 대처하여 주거, 행정, 문화 등 도시의 기능에 맞는 서비스를 제공하고 하기위한 센터가 필요하다. 도시의 통신망, 교통망, 시설물 등으로부터 도시정보를 수신하고 이를 통합적으로 분석하여 도시를 효과적으로 운영, 관리하고 거주민이나 관련 기관에 분석된 도시정보를 실시간으로 제공 해 주는 곳의 시설물 및 형태를 도시통합운영(관제)센터라 한다. 도시통합운영센터에서 서비스는 통합관제 플랫폼을 바탕으로 단위 서비스 간의 통합에서부터 도시를 구성하는 조직 사이의 수직적 통합과 각각의 계층에 놓인 서비스 사이의 수평적 통합으로 구성할 수 있다. 본고에서는 u-City 통합운영센터 플랫폼 및 구축방안에 대하여 알아보고 통합운영센터의 성공 방안에 대해 제언하였다.

• 한국식품위생안전성학회지
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• 제22권4호
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• pp.300-305
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• 2007

본 연구는 취나물, 고춧잎, 열무를 대상으로 건조에 따른 procymidone, diazinon의 잔류량의 경시적 변화를 연구할 목적으로 수행되었다. 실내풍건 방법으로 건조하는 경우, procymidone, diazinon의 잔류량이 증가하지만 수분함량의 감량을 고려하여 보정하면 $10{\sim}83%$ 감소하였고, 열풍건조 방법으로 건조하는 경우도 농약 잔류량은 증가하여도 수분함량의 감량을 고려하여 보정하면 $44{\sim}71%$ 감소하였다. 이 결과에 의하면, 건조에 의하여, 수분 보정한 농약잔류량이 대부분 감소하므로 건조농산물을 판정함에 있어 단순히 신선농산물의 기준에서 수분함량의 감량을 고려하여 기준 적용할 것이 아니라 건조과정 중 농약잔류량에 영향을 미치는 여러 요인을 고려한 추가연구가 필요하다고 판단된다.