• Title/Summary/Keyword: Center of Mass

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Component Analysis and Anti-Proliferative Effects of Ethanol Extracts of Fruits, Leaves, and Stems from Elaeagnus umbellata in HepG2 Cells (보리수나무 열매, 잎 및 줄기 에탄올 추출물의 함유성분 분석과 간암 세포 증식억제 효과)

  • Kim, Min-Ju;Lim, Jong-Soon;Yang, Seun-Ah
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.6
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    • pp.828-834
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    • 2016
  • The aim of this study was to evaluate the physicochemical properties and antioxidant and anti-proliferative activities of different plant parts of Elaeagnus umbellata Thunb. extracted with ethanol (EtOH). EtOH extract of stems presenting the highest content of polyphenols showed the strongest 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity ($EC_{50}=54.04{\mu}g/mL$). The total content of free amino acids decreased in the order of leaves (6,179.12 mg/100 g)> stems (1,211.69 mg/100 g)> fruits EtOH extract (378.88 mg/100 g), and asparagine (1,907.57 mg/100 g), ${\gamma}-aminobutyric$ acid (300.17 mg/100 g), and proline (233.48 mg/100 g) were the major free amino acid in leaves, stems, and fruits, respectively. Five phenolic compounds in each extract were measured by using liquid chromatography- tandem mass spectrometry, and gallic acid (98.95 mg/100 g) and (+)-catechin (1,575.99 mg/100 g) were present as major components in leaves and stems, respectively. EtOH extract of leaves showed the highest anti-proliferative activity against HepG2 cells as measured by 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazoliumbromide and lactate dehydrogenase assay but had no effects on Chang liver cells.

Volatile Flavor Components in Various Varieties of Pear (Pyrus pyrifolia N.) (배의 품종별 휘발성 향기성분)

  • Lee, Hae-Jung;Park, Eun-Ryong;Kim, Sun-Min;Kim, Ki-Yeol;Lee, Myung-Yul;Kim, Kyong-Su
    • Korean Journal of Food Science and Technology
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    • v.30 no.5
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    • pp.1006-1011
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    • 1998
  • Volatile flavor components in three varieties (shingo(niitaka), mansamgil (okusankichi) and chuwhang pears) of Pear (Pyrus pyrifolia N.) were extracted for 24 hours with pentane-diethylether (1 : 1, v/v) using the LLEP (liquid-liquid extraction & perforation). Neutral fraction was separated from the extract and then analyzed by GC-FID and GC/MS equipped with a fused silica capillary column (Carbowax 20M, HP). Individual components were identified by mass spectrometry and their retention indices. The totals of 52, 47 and 22 volatiles were identified in shingo, mansamgil and chuwhang pears, respectively. Ethyl acetate, propyl acetate, hexanal, 1-hexanol, ethyl butanoate, ethyl-3-hydroxy butanoate, ethyl-2-hydroxy propanoate were the main components in each samples, though there were several differeces in composition of volatile compounds. Total contents of volatile components isolated in shingo, mansamgil and chuwhang pears were 6.972, 2.776 and 2.653 mg/kg of pears.

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Concurrence of Apocrine Carcinoma, Mammary Gland Tumors and Bladder Transitional Cell Carcinoma in a Dog (개에서 땀샘 암종, 유선종양 및 방광 이행상피암종의 동시 발생)

  • Jung, Youn-Chol;Woo, Gye-Hyeong;Yun, Young-Min;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.33 no.1
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    • pp.74-79
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    • 2016
  • A 7-year-old female Pointer dog with multiple masses in the axilla, mammary gland, and bladder was submitted to the Pathology Department of the College of Veterinary Medicine in the Jeju National University. Grossly, mass between right axilla and 1st mammary gland, $15{\times}10cm$ in size, was well delineated and firm, slightly soft center, oval shape. And masses in right 1st, 3rd and 5th mammary gland were well delineated and sulphur yellow in color on the cut-surface. Numerous round to oval shaped masses, 0.3 to 2 cm in diameter were existed in the lung. Urinary bladder mucosa had rough and thick and round to oval papillary masses, 0.1 to 2 cm in diameter, on surface. Microscopically, masses in right axilla, 1st mammary gland, lung and axillary lymph node were composed of poorly differentiated tubules originated from apocrine gland. Lining neoplastic epithelium showed high mitotic figures, typical apical secretory blebs, and PAS-positive diastase-resistant cytoplasmic granules. Masses in 3rd and 5th mammary gland were confirmed as mammary complex adenoma and simple adenoma respectively. The masses in the urinary bladder were covered with stratified transitional epithelium with marked cellular atypia and high mitotic figures. Some neoplastic cells showed focal invasion into substantia propria of bladder. Immunohistochemaically, neoplastic transitional epithelium demonstrated positive reactions for cytokeratin 7, AE1/AE3, and MNF116. Based on the gross, histopathologic and immunohistochemical characteristics, this dog was diagnosed as apocrine carcinoma, mammary gland tumor including simple adenoma and complex adenoma and bladder transitional cell carcinoma. And distant metastases of apocrine carcinoma in right axilla were observed in axillary lymph node and lungs. This is the first report for concurrent occurrence of apocrine carcinoma, mammary gland tumor, and transitional cell carcinoma in a same dog.

Rapid Analytical Method of Volatile- and Semivolatile Organic Compounds in Water and their Monitoring in Water Treatment Plants (물 시료 중 휘발성 및 반휘발성 유기물질들의 빠른 분석법 및 정수처리 단계별 모니터링)

  • Shin, Ho-Sang;Ahn, Hye-Sil
    • Analytical Science and Technology
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    • v.17 no.3
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    • pp.240-250
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    • 2004
  • A gas chromatography-mass spectrometric (GC-MS) assay method was developed for the rapid and sensitive determination of volatile- and semivolatile organic compounds in water. Two hundreds mL of water sample was extracted in a 250 mL separatory funnel with 1 ml of pentane at pH 6.5. Fluorobenzene and 1,2-dichlorobenzene-d4 as internal standards were added to water sample and the solution was mechanically shaken for 5 min and analyzed by GC-MS (selected ion monitoring) without more any concentration or purification steps. The peaks had good chromatographic properties and the extraction of these compounds from water also gave relatively high recoveries with small variations. The range of detection limits of the assay was 0.5-10 ng/L. Turnaround time for up to about 40 samples was one day. This method is simple, convenient, and can be learned easily by relatively inexperienced personnel. This method was used to analyze 15 volatile- and semivolatile organic compounds in water of a Lake, and raw and treated water from three Water Treatment Plants in Korea. As the analytical results, benzene, toluene, xylene, isopropylbenzene, 1,3,5-trimethylbenzene, 1,2,4-trimethylbenzene, naphthalene and 2,4,6-trichlorophenol were detected at concentrations of up to 0.4, 1.9, 1.3, 0.2, 1.8, 13.0, 1.7 and $1.1{\mu}g/L$, respectively. But chlorobenzene, trichloroethylene, tetrachloroethylene, ethylbenzene, n-butylbenzene and dibromochloropropane levels during that period were not significant. The removal effect of the compounds in three Water Treatment Plants was calculated. The compounds studied were generally removed during conventional water treatment, especially during the active carbon filtration.

Long-Term Durability Estimation of Cementless Concrete Based on Alkali Activated Slag (알칼리 활성 슬래그 기반 무시멘트 콘크리트의 장기 내구성 평가)

  • Lee, Hyun-Jin;Lee, Seok-Jin;Bae, Su-Ho;Kwon, Soon-Oh;Lee, Kwang-Myong;Jung, Sang-Hwa
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.4 no.2
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    • pp.149-156
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    • 2016
  • It has been well known that concrete structures exposed to chloride and sulfate attack environments lead to significant deterioration in their durability due to chloride ion and sulfate ion attack. The purpose of this experimental research is to evaluate the long-term durability against chloride ion and sulfate attack of the alkali activated cementless concrete replacing the cement with ground granulated blast furnace slag. For this purpose, the cementless concrete specimens were made for water-binder ratios of 40%, 45%, and 50%, respectively and then this specimens were cured in the water of $20{\pm}3^{\circ}C$ and immersed in fresh water, 10% sodium sulfate solution for 28, 91, 182, and 365 days, respectively. To evaluate the long-term durability to chloride ion and sulfate attack for the cementless concrete specimens, the diffusion coefficient for chloride ion and compressive strength ratio, mass change ratio, and length change ratio were measured according to the NT BUILD 492 and JSTM C 7401, respectively. It was observed from the test results that the resistance against chloride ion and sulfate attack of the cemetntless concrete were comparatively largely increased than those of OPC concrete irrespective of water-binder ratio.

Density-based Topology Design Optimization of Piezoelectric Crystal Resonators (압전 수정진동자의 밀도법 기반 위상 최적설계)

  • Ha, Youn Doh;Byun, Taeuk;Cho, Seonho
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.27 no.2
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    • pp.63-70
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    • 2014
  • Design sensitivity analysis and topology design optimization for a piezoelectric crystal resonator are developed. The piezoelectric crystal resonator is deformed mechanically when subjected to electric charge on the electrodes, or vice versa. The Mindlin plate theory with higher-order interpolations along thickness direction is employed for analyzing the thickness-shear vibrations of the crystal resonator. Thin electrode plates are masked on the top and bottom layers of the crystal plate in order to enforce to vibrate it or detect electric signals. Although the electrode is very thin, its weight and shape could change the performance of the resonators. Thus, the design variables are the bulk material densities corresponding to the mass of masking electrode plates. An optimization problem is formulated to find the optimal topology of electrodes, maximizing the thickness-shear contribution of strain energy at the desired motion and restricting the allowable volume and area of masking plates. The necessary design gradients for the thickness-shear frequency(eigenvalue) and the corresponding mode shape(eigenvector) are computed very efficiently and accurately using the analytical design sensitivity analysis method using the eigenvector expansion concept. Through some demonstrative numerical examples, the design sensitivity analysis method is verified to be very efficient and accurate by comparing with the finite difference method. It is also observed that the optimal electrode design yields an improved mode shape and thickness-shear energy.

Effects of Plant Growth Regulators for Hard Wood and Cutting Time for Soft Wood on Rooting of Korean Native Spiraea spp. (숙지의 생장조절제 처리 및 녹지의 삽목시기가 한국 자생 조팝나무류의 발근에 미치는 영향)

  • Lee, Jeong Ho;Song, Cheon Young;Woo, Hyo Jin;Kwon, Oh Woung
    • FLOWER RESEARCH JOURNAL
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    • v.19 no.2
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    • pp.103-109
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    • 2011
  • This study was conducted to develop mass production method by proper cutting time, and the concentrations of plant growth regulators of Spiraea spp. Plants of hard wood was cut on March 3th, the rooting rate in S. salicifolia and S. cantoniensis was 11.3% comparatively higher than that about 5% in S. trichocarpa, S. miyabei, S. japonica, S. thunbergii and S. fritschiana. The rooting of control was 6.0%, however the $125{\sim}1,000mg{\cdot}L^{-1}$ IBA or NAA for 3 hour soaking was above 15.0% in the S. salicifolia. Therefore soaking in $125mg{\cdot}L^{-1}$ of IBA or NAA solution was recommended before cutting. The proper cutting time for soft wood from May 7 to September 17 in S. trichocarpa, S. cantoniensis, S. prunifolia, and S. thunbergii was September 17 when the soft stem was changed hard and the temperate was proper for rooting, high and low, $25{\pm}3^{\circ}C$ and $18{\pm}3^{\circ}C$. The rooting of September 17 was above 70% in S. salicifolia and S. fritschiana. However, the rooting from middle of May to early August was low below 20% in all the genus of Spiraea.

Analysis of Bone Mineral Density Status in Korean Mother : In the Center of One Obstetric Hospital (국내 산모의 골밀도 현황 분석 : 일개 산부인과 전문병원중심으로)

  • Kim, Young-Ran;Kim, Hye-Jin;Choi, So-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.4
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    • pp.320-328
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    • 2019
  • This study was conducted to provide basic data for prevention of osteoporosis by examining the factors affecting bone mineral density in pregnant mothers. This investigation was a descriptive research study that analyzed a total of 137 medical records. Differences in T-score between general and obstetric characteristics were assessed by independent t-tests and one way ANOVA followed by Scheffe's post-hoc test. The mean age of the subjects was 32.4 years and the mean T-score was 0.34. The BMI measured at 4 weeks after delivery was significantly higher in the underweight group than in the normal group and the overweight group (F=11.935, p<.001). The BMD was significantly higher in subjects with sufficient vitamin D than in subjects with insufficient vitamin D, in subjects with insufficient vitamin D than in subjects with deficiency vitamin D (F=4.906, P=0.009). BMD was significantly higher in cases without experience of abortion than those with more than one experience of abortion (t=4.264, p<.001), and the normal delivery was significantly higher than that of cesarean section (t= 2.019, p=.046). Based on the results of this study, it is necessary to actively prevent the factors affecting BMD during pregnancy and delivery. The findings presented herein can be used as basic data for the management of osteoporosis.

A Study on Quality Improvement and Verification of Recycled Coarse Aggregate for Concrete Using an Impact Crusher with Radial Rotation (방사형 회전이 추가된 임팩트 크러셔를 이용한 콘크리트용 순환굵은골재 품질향상 및 검증 연구)

  • Jeon, Duk-Woo;Kim, Yong-Seong;Jeon, Chan-Soo;Choi, Won-Young;Cho, Won-Ig
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.10 no.2
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    • pp.133-142
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    • 2022
  • The purpose of this study is to develop an impact crusher with a radial rotating plate installed at the bottom, which is a shock absorber that can produce high-quality recycled coarse aggregate for concrete and to verify the effect of improving the quality performance of recycled coarse aggregate and its applicability through concrete tests. As a result, it showed improved quality in all items such as absolute dry density, absorption rate, abrasion resistance, Particle shape judgment rate, amount lost in the 0.08 mm sieve passing test, alkali aggregate reaction, clay mass, stability, and impurity content, and it was found to meet the criteria of recycled aggregate quality standards. In addition, the air volume and slump of concrete to which recycled coarse aggregate is applied meet all domestic standards. According to the test results of the compressive strength characteristics by age of concrete according to the mixing ratio of the recycled coarse aggregate, it was confirmed that the mixing ratio of the recycled coarse aggregate was applicable up to 60 %.

Research on Korean Language Textbooks to Activate Media Literacy for the Era of Cultural Convergence (문화융합시대의 미디어 리터러시 활성화를 위한 국어교재 연구)

  • Lim, Ji-Won
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.7
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    • pp.389-395
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    • 2020
  • This discussion is a study that proposes to introduce a strategy to positively interpret the narrative meaning in media language based on a generalized cognitive environment in order to activate correct media literacy in the era of cultural convergence. have. In particular, by using advertising content that has the most reinforced creativity related to cultural interpretation, it was induced to grasp the informational manifestation of that era and to reproduce meaning interpretation with relevance. In addition, it attempted to utilize an argumentative writing strategy in the process of reproducing Korean language learners' writing, which was capable of cognitive interpretation. The intention of the public service advertisement content developer always expects a positive effect in the social and cultural aspect, and the learner dreams of reflection and a correct future through the effect. The research on activating media literacy in the era of cultural convergence, which I intended, has not yet been much discussed. We hope that the proposed discussion of this study will be actively utilized in mass media language education of the contents of textbooks for Korean language learners, and we are sorry for the part that does not contain quantitative analysis contents, and we expect the results in subsequent thesis.