• IMMUNE NETWORK
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• 제12권2호
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• pp.41-47
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• 2012

Contemporary studies illustrate that peripheral injuries activate glial components of the peripheral and central cellular circuitry. The subsequent release of glial stressors or activating signals contributes to neuropathic pain and neuroinflammation. Recent studies document the importance of glia in the development and persistence of neuropathic pain and neuroinflammation as a connecting link, thereby focusing attention on the glial pathology as the general underlying factor in essentially all age-related neurodegenerative diseases. There is wide agreement that excessive glial activation is a key process in nervous system disorders involving the release of strong pro-inflammatory cytokines, which can trigger worsening of multiple disease states. This review will briefly discuss the recent findings that have shed light on the molecular and cellular mechanisms of glia as a connecting link between neuropathic pain and neuroinflammation.

• 대한지리학회지
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• 제39권3호
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• pp.444-456
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• 2004

최근 GIS 분야에서는 GIS와 동적 프로세스 모델링에 기반한 셀룰라 오토마타(CA)의 결합을 통한 공간모델링 연구가 활발히 진행되고 있다. 그러나 선행 연구에서의 CA 모델링은 해결하고자 하는 문제의 핵심이 되는 규칙을 찾아내는 기능은 제공하지 못하고 있다. 본 연구에서는 GIS와 지식 발견 기법을 이용하여 공간 연관규칙을 추출하는 방법론을 제시하고 실제 사례에 적용하였다. 이러한 방법론의 제시는 CA 모델링의 기능을 더욱 향상시킬 것으로 기대된다. 또한 본 연구에서 사례로 적용한 도시지역 확장 외에 다양한 문제에 대한 활용이 가능할 것으로 판단된다.

• Asian-Australasian Journal of Animal Sciences
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• 제8권6호
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• pp.599-605
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• 1995

The ultrastructures of in vitro-derived bovine blastocysts have been compared with those of blastocysts obtained from a superovulated cow. In vivo blastocysts obtained from the uterus showed well-differentiated features, while in vitro-derived embryos, which were developed from in vitro fertilized ovum, showed insufficient cellular organizations. In vitro-derived embryos contained many undefined cellular organizations in the perivitelline spaces compared with in vivo-derived blastocysts. Other features of in vivo and in vitro blastocysts were characterized by differential development of microvilli projection into blastocoele from the surface of the trophoblast cells. The conceivable reason for the difference between in vivo and in vitro developments of bovine embryos is that it is likely that in vitro culture system adopted in the present experiment may not be sufficient for better embryonic development.

• IMMUNE NETWORK
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• 제12권4호
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• pp.139-147
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• 2012

Although adoptive T cell therapy (ACT) has become a promising immunotherapeutic regime for cancer treatment, its effectiveness has been hindered by several inherent shortcomings regarding safety and efficacy. During the past few decades, several strategies for enhancing the efficacy of ACT have been developed and introduced in clinic. This review will summarize not only the past approaches but also the latest strategies which have been shown to enhance the anticancer activity of ACT.

• Water Engineering Research
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• 제4권4호
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• pp.187-192
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• 2003

The rainfall observation systems have largely been improved in Japan. The Japan Meteorological Agency, prefecture governments, and other administrative bodies have also increased the number of rain gauges thru out the country. The density of observatories is now one per several $\km^2$. Heavy rainfall information systems have been improved. Besides it, the Internet was popularized in the late 1990s, and has been used to transmit data of heavy rainfall. Internet accessible cellular phones have been popular in Japan since 1999. Such phones are expected to be useful in the field of disaster warning announcements, because they can automatically notify users bye-mail of pending disasters. The use of the Internet during natural disasters is groundbreaking in Japan today. However, in order to use disaster information effectively on Internet it is necessary to investigate how to use the information during the rainfall disaster. Therefore in our study we suggest methods on the effective construction and their use of information technology on Internet.

• ETRI Journal
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• 제19권3호
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• pp.303-315
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• 1997

This appendix deals with the Korean air interface standard, TTA-62, for CDMA Mobile Systems, (CMS) [1]-[2]. The standard has been set up by Telecommunications Technology Association (TTA) which is a standardization organization in Korea [3]. This standard is an important specification that should be determined prior to the development of a digital cellular system. The CMS has been developed on the basis of this standard and the papers published in this special issue are the results of the CMS development. This appendix also describes the technical commonality of these papers. It covers the outline of the air interface and protocol specifications. The outline includes its major characteristics, radio protocol architecture, functionalties, and call processing. A comparison is also given between TTA-62 and IS-95[4], a North American digital cellular standard.

• 산업경영시스템학회지
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• 제21권45호
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• pp.145-154
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• 1998

The effects of secondary task on driving performance and subjective workload were investigated during a simulated driving. The driving performance was determined by the appropriateness of break timing. The driving simulator was provided by the Korea Road Traffic Safety Association. The subjective workload was tested by using a multidimensional measure such as NASA-TLX. Road was categorized into two types: narrow alley and wide street. The secondary task included pushing the number on the cellular phone, pushing radio channel, and conversing with a passenger. Seventeen subjects volunteered in the study. The data were analyzed by using SAS. Results showed that using the cellular phone and pushing channel during driving caused 3∼22% decline of driving performance and 42∼59% increase of subjective workload respectively. These results indicated that the secondary task could be potentially dangerous although there was not a significant performance decrease due to the notable increase of mental workload. In the future, if we can use a more sensitive and realistic driving simulator, the effects of secondary task under a dynamic driving situation can be investigated.

• IMMUNE NETWORK
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• 제13권1호
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• pp.1-9
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• 2013

Autophagy is a fundamental cellular process in eukaryotic cells for maintaining homeostasis by degrading cellular proteins and organelles. Recently, the roles of autophagy have been expanded to immune systems, which in turn modulate innate immune responses. More specifically, autophagy acts as a direct effector for protection against pathogens, as well as a modulator of pathogen recognition and downstream signaling in innate immune responses. In addition, autophagy controls autoimmunity and inflammatory disorders by negative regulation of immune signaling. In this review, we focus on recent advances in the role of autophagy in innate immune systems.

• 한국정보통신학회논문지
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• 제12권6호
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• pp.1016-1021
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• 2008

많은 무선기술이 개발되었지만, 그 기술들은 적용사례와 대역폭에서 한계를 가지고 있다. WLAN과 3G 네트워크는 무선통신을 도와주기 위한 플랫폼으로 나왔다. 그러나 서로 다른 네트워크 터미널의 이동성은 여러 리스크를 발생시킨다. 통신 보안과 효과적인 증명이 실행되어야 한다. 이 논문의 주제는 통합된 WLAN/3G 네트워크에 관한 증명방법의 분석에 있다.

• Laboraroty Animal Research
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• 제34권4호
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• pp.203-210
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• 2018

Stress severely disturbs physiological and mental homeostasis which includes adult neurogenesis in hippocampus. Neurogenesis in hippocampus is a key feature to adapt to environmental changes and highly regulated by multiple cellular signaling pathways. The primary cilium is a cellular organelle, which acts as a signaling center during development and neurogenesis in adult mice. However, it is not clear how the primary cilia are involved in the process of restraint (RST) stress response. Using a mouse model, we examined the role of primary cilia in repeated and acute RST stress response. Interestingly, RST stress increased the number of ciliated cells in the adult hippocampal dentate gyrus (DG). In our RST model, cell proliferation in the DG also increased in a time-dependent manner. Moreover, the analysis of ciliated cells in the hippocampal DG with cell type markers indicated that cells that were ciliated in response to acute RST stress are neurons. Taken together, these findings suggest that RST stress response is closely associated with an increase in the number of ciliated neurons and leads to an increase in cell proliferation.