• 제목/요약/키워드: Cellular association

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세포교정영양요법(OCNT)을 이용한 암피로증후군, 전이암 환자 사례 연구 (A Case Study of a Patient with Cancer Fatigue Syndrome and Cancer Metastases who Received Ortho-Cellular Nutrition Therapy (OCNT))

  • 최연
    • 셀메드
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    • 제12권5호
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    • pp.4.1-4.3
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    • 2022
  • Objective: A Case Study of a Patient with Cancer Fatigue Syndrome and Cancer Metastases who Received Ortho-Cellular Nutrition Therapy (OCNT) Methods: The patient is a Korean woman aged 61 years. 13 years ago, she was diagnosed with stage 1 breast cancer and underwent surgery, chemotherapy, and radiation therapy. owever, 13 years later, the disease spread to the lungs and brain. Results: Following nutritional therapy, cancer fatigue syndrome improved. Conclusion: Nutritional therapy can be beneficial for cancer fatigue syndrome, a condition that remains undiagnosed and untreated.

세포교정영양요법(OCNT)을 이용한 중족골 골절 환자 사례 연구 (A Case Study on the Metatarsal Fractures Patients Using Ortho-Cellular Nutrition Therapy (OCNT))

  • 강선희
    • 셀메드
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    • 제13권12호
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    • pp.43.1-43.8
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    • 2023
  • Objective: A case report of pain relief and fracture recovery by ortho-cellular nutrition therapy in a patient with 2nd, 3rd, and 4th metatarsal fractures (closed). Methods: A Korean woman in her 50s was diagnosed with 2nd, 3rd, and 4th metatarsal fractures (closed) with severe initial pain and fractures. Surgery was recommended but could not be performed immediately due to her situations at work. Results: With OCNT performed immediately after the fracture, the pain completely disappeared, and even during subsequent recovery, recovery was faster than in other fracture cases. Conclusion: OCNT may help patients with similar problems relieve symptoms and recover.

세포교정영양요법(OCNT)을 이용한 골다공증 환자 사례 연구 (A Case Study on an Osteoporosis Patient Using Ortho-Cellular Nutrition Therapy (OCNT))

  • 차명진
    • 셀메드
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    • 제13권12호
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    • pp.47.1-47.8
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    • 2023
  • Objective: A case report on the improvement of symptoms in an osteoporosis patient using ortho-cellular nutrition therapy Methods: Currently a 70 years old Korean woman was diagnosed with osteoporosis in her late 50s around 2010 and continued to receive injection treatments once every three months. Her T-score did not improve, and fractures continued to occur in the ankles, wrists, shoulders, ribs, etc., even from light impacts. Results: The patient underwent an osteoporosis test in February 2019, which resulted in an average T-score of -2.5 or less, equivalent to being diagnosed with osteoporosis. OCNT has been performed since May 2019 (late 60s), and in the test received in April 2020, the T-score value improved to over -2.5 and was determined normal at the hospital. Since then, OCNT continued without any further injection treatments. Unlike before, even when she fell hard, she only suffered bruises without fractures, and no additional fractures have occurred. Conclusion: OCNT may help patients with similar problems relieve symptoms and recover.

셀룰러 망에서 프로파일 기반 위치관리를 위한 위치영역 리스트 생성 (Location Area List Generation for Profile Based Location Management in Cellular Networks)

  • 조현준
    • 컴퓨터교육학회논문지
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    • 제8권6호
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    • pp.123-132
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    • 2005
  • 이동망의 위치관리에서 위치갱신 비용 최소화를 위한 많은 연구 결과들이 있다. 위치갱신 비용의 최소화를 위해서는 각 사용자들의 이동 패턴을 고려해야만 한다. 본 논문은 과거의 사용자 이동에 대한 이력으로부터 각 사용자에 대한 위치영역 리스트 생성과 이를 위한 3 단계 페이징 방안을 제안한다. 사용자의 이동은 공간적으로 뿐만 아니라 시간적으로도 규칙적인 패턴이 존재한다. 따라서 제안된 위치영역 리스트 생성방안은 이상의 2가지 측면에서 사용자의 방문빈도를 이용하여 규칙성을 발견하고, 이에 대한 위치영역리스트를 생성한다. 제안된 방안의 성능분석 위해서 제안된 방안에 대하여 사용자 이동 패턴을 고려한 모의실험을 수행하였다. 모의실험 결과 제안된 방안이 위치관리 비용 측면에서 장점이 있음이 확인되었다.

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Increased Association of ${\alpha}$-synuclein to Perturbed Cellular Membranes

  • Kim, Yoon-Suk;Lee, Seung-Jae
    • 대한의생명과학회지
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    • 제17권2호
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    • pp.167-171
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    • 2011
  • [ ${\alpha}$ ]synuclein (${\alpha}$-syn) is implicated in the pathogenesis of Parkinson's disease (PD) and other related diseases. We have previously reported that ${\alpha}$-syn binds to the cell membranes in a transient and reversible manner. However, little is known about the physiologic function and/or consequence of this association. Here, we examined whether chemically induced perturbations to the cellular membranes enhance the binding of ${\alpha}$-syn, based on hypothesis that ${\alpha}$-syn may play a role in maintenance of membrane integrity or repair. We induced membrane perturbations or alterations in ${\alpha}$-syn-overexpressing human neuroblastoma cells (SH-SY5Y) by treating the cells with hydrogen peroxide ($H_2O_2$) or oleic acid. In addition, membranes fractionated from these cells were perturbed by treating them with proteinase K or chloroform. Dynamic interaction of ${\alpha}$-syn to the membranes was analyzed by the chemical cross-linking assay that we developed in the previous study. We found that membrane interaction of ${\alpha}$-syn was increased upon treatment with membrane-perturbing reagents in a dose and time dependent manner. These results suggest that perturbations in the cellular membranes cause increased binding of ${\alpha}$-syn, and this may have significant implication in the physiological function of ${\alpha}$-syn in cells.

Dynamic Cell Reconfiguration Framework for Energy Conservation in Cellular Wireless Networks

  • Son, Kyuho;Guruprasad, Ranjini;Nagaraj, Santosh;Sarkar, Mahasweta;Dey, Sujit
    • Journal of Communications and Networks
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    • 제18권4호
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    • pp.567-579
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    • 2016
  • Several energy saving techniques in cellular wireless networks such as active base station (BS) selection, transmit power budget adaptation and user association have been studied independently or only part of these aspects have been considered together in literature. In this paper, we jointly tackle these three problems and propose an integrated framework, called dynamic cell reconfiguration (DCR). It manages three techniques operating on different time scales for ultimate energy conservation while guaranteeing the quality of service (QoS) level of users. Extensive simulations under various configurations, including the real dataset of BS topology and utilization, demonstrate that the proposed DCR can achieve the performance close to an optimal exhaustive search. Compared to the conventional static scheme where all BSs are always turned on with their maximum transmit powers, DCR can significantly reduce energy consumption, e.g., more than 30% and 50% savings in uniform and non-uniform traffic distribution, respectively.

Identification of SNPs in Cellular Retinol Binding Protein 1 and Cellular Retinol Binding Protein 3 Genes and Their Associations with Laying Performance Traits in Erlang Mountainous Chicken

  • Wang, Yan;Xiao, Li-Hua;Zhao, Xiao-Ling;Liu, Yi-Ping;Zhu, Qing
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권8호
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    • pp.1075-1081
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    • 2014
  • CRBP1 (cellular retinol binding protein 1) and CRBP3 (cellular retinol binding protein 3), are important components of the retinoid signaling pathway and take part in vitamin A absorption, transport and metabolism. Based on the role of vitamin A in chicken laying performance, we investigated the polymorphism of CRBP1 and CRBP3 genes in 349 chickens using single strand conformation polymorphism and DNA sequencing methods. Only one polymorphism was identified in the third intron of CRBP1, two polymorphisms were detected in CRBP3; they were located in the second intron and the third intron respectively. The association studies between these three SNPs and laying performance traits were performed in Erlang mountainous chicken. Notably, the SNP g.14604G>T of CRBP1 was shown to be significantly associated with body weight at first egg (BWFE), age at first egg (AFE), weight at first egg (WFE) and total number of eggs with 300 age (EN). The CRBP3 polymorphism g.934C>G was associated with AFE, and the g.1324A>G was associated with AFE and BWFE, but none of these polymorphisms were associated with egg quality traits. Haplotype combinations constructed on these two SNPs of CRBP3 gene were associated with BWFE and AFE. In particular, diplotype H2H2 had positive effect on AFE, BWFE, EN, and average egg-laying interval. We herein describe for the first time basic research on the polymorphism of chicken CRBP1 and CRBP3 genes that is predictive of genetic potential for laying performance in chicken.

치성낭종 상피세포의 증식, 분화 및 세포능동사망현상에 관한 면역조직화학적 연구 (AN IMMUNOHISTOCHEMICAL STUDY ON PROLIFERATION, DIFFERENTIATION, AND APOPTOSIS IN THE EPITHELIAL CELLS OF THE ODONTOGENIC CYSTS)

  • 정성훈;박영욱;주재용;이석근
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제26권5호
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    • pp.470-480
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    • 2000
  • The epithelium of odontogenic cyst seems to be in a specific status of cellular proliferation and cytodifferentiation. With the identification of various genes, which play essential roles in the specific stages of cellular proliferation and differentiation, the cellular conditions of odontogenic cyst epithelium need to be reevaluated. This study aimed to estimate the degree of proliferating, differentiating and apoptotic activities of odontogenic cyst epithelium using antisera of PCNA, Ki-67, MPM-2, transglutaminase C, heat shock protein 70 and $ApopTag$^{(R)}$. method in 19 cases of odontogenic cysts. Cellular changes of the cyst epithelium were measured by intensity of each immunohistochemical staining. Results were as follows: 1. The proliferating activity of the cyst epithelium was slightly lower than that of normal oral mucosal epithelium, with the use of primary antibodies against PCNA, Ki-67, and MPM-2. And the proliferating activity of the epithelium in OKC group was even higher than that of the epithelium in non-OKC group. 2. The odontogenic cysts showed weakly positive reaction with transglutaminase C, but strongly positive reaction with HSP 70. 3. Occasionally, only a few apoptotic cell was observed in the superficial keratin layer of OKC. 4. The hyperplastic cyst epithelium infiltrated with mild inflammatory cells showed diffusely positive reaction with different proliferating factors. From the above results, we presumed that the endogenous proliferating and differentiating activity of the cyst epithelium was slightly lower than that of normal oral mucosal epithelium, and also supposed that the cyst epithelium could be reactivated for the further proliferation by the exogenous factors, such as inflammatory reaction and any chemicophysical irritations.

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