• ETRI Journal
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• v.44 no.6
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• pp.966-976
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• 2022

Optical wireless communication, or free space optics, is a promising solution for backhauls in sixth-generation mobile systems. However, the susceptibility of optical links to weather conditions has led to FSO links being furnished with radio frequency (RF) backups. These Hybrid FSO/RF systems provide enhanced link availability but lead to RF resource wastage. Cognitive radio technology, in contrast, is well known for its optimal use of RF resources and may be combined with an FSO link to create a Cognitive Hybrid FSO/RF system. This work uses such a system to analyze a configuration for a mobile backhaul in sixth-generation mobile systems. This configuration can seamlessly coexist with established large scale RF cellular networks. The performance of this configuration is analyzed with respect to outage probability and average bit error by considering the impact of optical channel turbulence, misalignment loss, RF interference, and noise. Mathematical closed-form expressions are verified by simulations.

• IMMUNE NETWORK
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• v.20 no.3
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• pp.22.1-22.21
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• 2020

In the progression of atherosclerosis, macrophages are the key immune cells for foam cell formation. During hyperlipidemic condition, phagocytic cells such as monocytes and macrophages uptake oxidized low-density lipoproteins (oxLDLs) accumulated in subintimal space, and lipid droplets are accumulated in their cytosols. In this review, we discussed the characteristics and phenotypic changes of macrophages in atherosclerosis and the effect of cytosolic lipid accumulation on macrophage phenotype. Due to macrophage plasticity, the inflammatory phenotypes triggered by oxLDL can be re-programmed by cytosolic lipid accumulation, showing downregulation of NF-κB activation followed by activation of anti-inflammatory genes, leading to tissue repair and homeostasis. We also discuss about various in vivo and in vitro models for atherosclerosis research and next generation sequencing technologies for foam cell gene expression profiling. Analysis of the phenotypic changes of macrophages during the progression of atherosclerosis with adequate approach may lead to exact understandings of the cellular mechanisms and hint therapeutic targets for the treatment of atherosclerosis.

• Journal of Communications and Networks
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• v.7 no.2
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• pp.157-170
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• 2005

The combination of multiple antennas and multi-carrier code division multiple-access (MC-CDMA) is a strong candidate for the downlink of the next generation mobile communications. The study of such systems in scenarios that model real-life trans-missions is an additional step towards an optimized achievement. We consider a realistic MIMO channel with two or four transmit antennas and up to two receive antennas, and channel state information (CSI) mismatches. Depending on the mobile terminal (MT) class, its number of antennas or complexity allowed, different data-rates are proposed with turbo-coding and asymptotic spectral efficiencies from 1 to 4.5 bit/s/Hz, using three algorithms developed within the European IST-MATRICE project. These algorithms can be classified according to the degree of CSI at base-station (BS): i) Transmit space-frequency prefiltering based on constrained zero-forcing algorithm with complete CSI at BS; ii) transmit beamforming based on spatial correlation matrix estimation from partial CSI at BS; iii) orthogonal space-time block coding based on Alamouti scheme without CSI at BS. All presented schemes require a reasonable complexity at MT, and are compatible with a single-antenna receiver. A choice between these algorithms is proposed in order to significantly improve the performance of MC-CDMA and to cover the different environments considered for the next generation cellular systems. For beyond-3G, we propose prefiltering for indoor and pedestrian microcell environments, beamforming for suburban macrocells including high-speed train, and space-time coding for urban conditions with moderate to high speeds.

• Molecules and Cells
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• v.20 no.1
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• pp.1-16
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• 2005

The peptidyl transferase center (PTC) is located in a protein free environment, thus confirming that the ribosome is a ribozyme. This arched void has dimensions suitable for accommodating the 3'ends of the A-and the P-site tRNAs, and is situated within a universal sizable symmetry-related region that connects all ribosomal functional centers involved in amino-acid polymerization. The linkage between the elaborate PTC architecture and the A-site tRNA position revealed that the A-to P-site passage of the tRNA 3'end is performed by a rotatory motion, which leads to stereochemistry suitable for peptide bond formation and for substrate mediated catalysis, thus suggesting that the PTC evolved by genefusion. Adjacent to the PTC is the entrance of the protein exit tunnel, shown to play active roles in sequence-specific gating of nascent chains and in responding to cellular signals. This tunnel also provides a site that may be exploited for local co-translational folding and seems to assist in nascent chain trafficking into the hydrophobic space formed by the first bacterial chaperone, the trigger factor. Many antibiotics target ribosomes. Although the ribosome is highly conserved, subtle sequence and/or conformational variations enable drug selectivity, thus facilitating clinical usage. Comparisons of high-resolution structures of complexes of antibiotics bound to ribosomes from eubacteria resembling pathogens, to an archaeon that shares properties with eukaryotes and to its mutant that allows antibiotics binding, demonstrated the unambiguous difference between mere binding and therapeutical effectiveness. The observed variability in antibiotics inhibitory modes, accompanied by the elucidation of the structural basis to antibiotics mechanism justifies expectations for structural based improved properties of existing compounds as well as for the development of novel drugs.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.36S no.12
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• pp.10-19
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• 1999

Cellular Automata Neural Systems(CANS) are neural networks based on biological development and evolution. Each neuron of CANS has local connection and acts as a form of pulse according to the dynamics of the chaotic neuron. CANS are generated from initial cells according to the CA rule. In the previous study, to obtain the useful ability of CANS, we make the pattern of initial cells evolve. However, it is impossible to represent all solution space, so we propose an evolving method of CA rule to overcome this defect in this paper. DNA coding has the redundancy and overlapping of gene and is apt for the representation of the rule. In this paper, we show the general expression of CA rule and propose translation method from DNA code to CA rule. The effectiveness of the proposed scheme was verified by applying it to the navigation problem of autonomous mobile robot.

• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.3
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• pp.293-302
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• 2016

In this paper we analyze the CA formed by combining the uniform 102 CA $\mathbb{C}_u$ and the m-cell 90/150 hybrid CA $\mathbb{C}_h$ whose characteristic polynomial is $(x+1)^m$. We analyze cycle structures of complemented group CA derived from $\mathbb{C}_u$ and propose a condition of complemented CA dividing the entire state space into smaller cycles of equal lengths. And we analyze the cycle structure of complemented group CA $\mathbb{C}^{\prime}$ derived from the CA $\mathbb{C}$ formed by combining $\mathbb{C}_u$ and $\mathbb{C}_h$ with complement vector F such that $(T+I)^{q-1}F{\neq}0$ where $(x+1)^q$ is the minimal polynomial of $\mathbb{C}$.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.18 no.9
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• pp.1030-1038
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• 2007

This paper presents the measurement results of strength of electromagnetic wave for GSM-900/GSM-1800 band which is used in Europe. The Giryong village and Sosan field are selected as candidate regions according to the measurement results in Gijang-gun, Busan. The vertical polarizations is about 12 dBm higher than horizontal polarization at two candidate places, and it is measured 25 dBm lower than urban. The maximum value of measured strength of vertical polarizations in the cellular/GSM-900 bands are -65 dBm at Giryong village and -69 dBm at Sosan field, respectively. The maximum value of measured results of PCS/GSM-1800 bands are -90.5 dBm at Giryong village and -85 dBm at Sosan field, respectively, We confirm that the receiving strength of electromagnetic wave are very weak below -65 dBm at two candidate places and the signals of GSM frequency bands not affect to conversional system, then it is considered as a suitable place for GSM mobile field test.

• Journal of Periodontal and Implant Science
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• v.49 no.4
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• pp.258-267
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• 2019

Purpose: Increased bone regeneration has been achieved through the use of stem cells in combination with graft material. However, the survival of transplanted stem cells remains a major concern. The purpose of this study was to evaluate the viability of transplanted mesenchymal stem cells (MSCs) at an early time point (24 hours) based on the type and form of the scaffold used, including type I collagen membrane and synthetic bone. Methods: The stem cells were obtained from the periosteum of the otherwise healthy dental patients. Four symmetrical circular defects measuring 6 mm in diameter were made in New Zealand white rabbits using a trephine drill. The defects were grafted with 1) synthetic bone (${\beta}$-tricalcium phosphate/hydroxyapatite [${\beta}-TCP/HA$]) and $1{\times}10^5MSCs$, 2) collagen membrane and $1{\times}10^5MSCs$, 3) ${\beta}-TCP/HA+collagen$ membrane and $1{\times}10^5MSCs$, or 4) ${\beta}-TCP/HA$, a chipped collagen membrane and $1{\times}10^5MSCs$. Cellular viability and the cell migration rate were analyzed. Results: Cells were easily separated from the collagen membrane, but not from synthetic bone. The number of stem cells attached to synthetic bone in groups 1, 3, and 4 seemed to be similar. Cellular viability in group 2 was significantly higher than in the other groups (P<0.05). The cell migration rate was highest in group 2, but this difference was not statistically significant (P>0.05). Conclusions: This study showed that stem cells can be applied when a membrane is used as a scaffold under no or minimal pressure. When space maintenance is needed, stem cells can be loaded onto synthetic bone with a chipped membrane to enhance the survival rate.

• Journal of Korean Society of Transportation
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• v.22 no.4 s.75
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• pp.147-158
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• 2004

A class of SWP(Stochastic Wane Propagation) models microscopically mimics individual vehicles' stochastic behavior and traffic jam propagation with simplified car-following models based on CA(Cellular Automata) theory and macroscopically captures dynamic traffic flow relationships based on statistical physics. SWP model, a program-oriented model using both discrete time-space and integer data structure, can simulate a huge road network with high-speed computing time. However, the model has shortcomings to both the capturing of low speed within a jam microscopically and that of the density and back propagation speed of traffic congestion macroscopically because of the generation of spontaneous jam through unrealistic collision avoidance. In this paper, two additional rules are integrated into the NaSch model. The one is SMR(Stopping Maneuver Rule) to mimic vehicles' stopping process more realistically in the tail of traffic jams. the other is LAR(Low Acceleration Rule) for the explanation of low speed characteristics within traffic jams. Therefore, the CA car-following model with the two rules prevents the lockup condition within a heavily traffic density capturing both the stopping maneuver behavior in the tail of traffic jam and the low acceleration behavior within jam microscopically, and generates more various macroscopic traffic flow mechanism than NaSch model's with the explanation of propagation speed and density of traffic jam.

• Spatial Information Research
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• v.22 no.2
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• pp.53-62
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• 2014

The floor field model is the micro pedestrian model based on a cellular automata for modeling pedestrian movement in the interior space using the static and dynamic floor field. It regards a form of pedestrian as square but the actual pedestrian's shape and size are similar to ellipsoid or rectangle. Because of this, we are difficult to give a rotation effect to pedestrians and there is a limit to reflect an impact of clogging and jamming. Also, this model is not able to reflect an impact of a posture and visibility effectively in the pedestrian movement. In this study, we suggest the improved pedestrian model incorporating the actual shape and size of pedestrian. The pedestrian's shape is defined not square but rectangle which is close to the actual body size of Korean. Also, we define the model which is able to represent the impact of clogging and jamming between pedestrians by adding the pedestrian's posture. We develop the simulator for testing the suggested model and study the difference between two models by comparing a number of effects. As a result, we could confirm solving the problem with dynamic value in the existed model and reflecting the panic effect in evacuation situation.