• YAKHAK HOEJI
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• v.41 no.4
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• pp.433-438
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• 1997

MT 51005 as a potent inhibitor of phospholipase C(PLC) was purified from the culture broth of a fungal strain No. 51005 isolated from soil. It was identified as a benzaldehyde d erivative, anguillosporal. by the physico-chemical properties and spectroscopic data. Anguillosporal showed the inhibitory activity against purified PLC with an $IC_{50}\;of\;13{\mu}g/ml$. And it also inhibited the formation of inositol phosphates($IP_t$) in platelet-derived growth factor(PDGF)-stimulated $NIH3T3{\gamma}1$ cells with an $IC_{50}\;of\;0.8{\mu}g/ml$.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.7
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• pp.1602-1608
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• 2013

PoC (Push-to-Talk over Cellular) provides one-to-one as well as one-to-many communications with VoIP technology based on SIP over cellular networks. According to above property, PoC is considered as perscrptive technology for public protection for disaster relief networks. For this networks, group communication is the essential function. However, since current standardization process takes into general scenarios account without any consideration for mentioned networks, it have some problems in the point of adaptability. To solve above problem, in this paper, we propose how to reduce the overhead on the PoC server to reduce the transmission delay. Simulation results are shown to evaluate the improved performance.

• Molecules and Cells
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• v.21 no.3
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• pp.315-329
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• 2006

Two, well characterized cationic channels, the ryanodine receptor (RyR) and the canonical transient receptor potential cation channel (TRPC) are briefly reviewed with a particular attention on recent developments related to the interplay between the two channel families.

• Information and Communications Magazine
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• v.30 no.8
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• pp.11-19
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• 2013

본고에서는 M2M/IoT 통신의 실현을 위한 무선 통신망 기술을 알아보고 IoT 통신을 위한 요구사항과 이를 해결하기 위한 연구 동향을 살펴본다. 특히, 많은 수의 IoT 디바이스가 싱크 노드를 이용하여 IP 망에 접속하는 Wireless Sensor network(WSN)에서의 문제와, LTE-A와 같은 cellular 망을 이용하여 접속하는 IoT 서비스로 나누어 논의한다. WSN관점에서는 에너지에 대한 제약이 심한 환경을 고려하여 발생할 수 문제점들을 분류하고 이에 대한 다양한 해결책을 제시하며, Cellular 망에서는 현재의 LTE-A 망에 많은 수의 IoT 디바이스가 연결될 경우 발생할 수 있는 문제점들을 논하고 기존의 통신에 영향을 최소화 하며 IoT 서비스를 공존할 수 있는 연구 동향을 논한다.

• Molecules and Cells
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• v.40 no.5
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• pp.315-321
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• 2017

The inositol polyphosphates are a group of multifunctional signaling metabolites whose synthesis is catalyzed by a family of inositol kinases that are evolutionarily conserved from yeast to humans. Inositol polyphosphate multikinase (IPMK) was first identified as a subunit of the arginine-responsive transcription complex in budding yeast. In addition to its role in the production of inositol tetrakis- and pentakisphosphates ($IP_4$ and $IP_5$), IPMK also exhibits phosphatidylinositol 3-kinase (PI3-kinase) activity. Through its PI3-kinase activity, IPMK activates Akt/PKB and its downstream signaling pathways. IPMK also regulates several protein targets non-catalytically via protein-protein interactions. These non-catalytic targets include cytosolic signaling factors and transcription factors in the nucleus. In this review, we highlight the many known functions of mammalian IPMK in controlling cellular signaling networks and discuss future challenges related to clarifying the unknown roles IPMK plays in physiology and disease.

• Molecules and Cells
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• v.25 no.3
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• pp.417-427
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• 2008

Comparison of maps and QTLs between populations may provide us with a better understanding of molecular maps and the inheritance of traits. We developed and used two reciprocal $BC_1F_1$ populations, IP/DS//IP and IP/DS//DS, for QTL analysis. DS (Dasanbyeo) is a Korean tongil-type cultivar (derived from an indica x japonica cross and similar to indica in its genetic make-up) and IP (Ilpumbyeo) is a Korean japonica cultivar. We constructed two molecular linkage maps corresponding to each backcross population using 196 markers for each map. The length of each chromosome was longer in the IP/DS//IP population than in the IP/DS//DS population, indicating that more recombinants were produced in the IP/DS//IP population. Distorted segregation was observed for 44 and 19 marker loci for the IP/DS//IP and IP/DS//DS populations, respectively; these were mostly skewed in favor of the indica alleles. A total of 36 main effect QTLs (M-QTLs) and 15 digenic epistatic interactions (E-QTLs) were detected for the seven traits investigated. The phenotypic variation explained (PVE) by M-QTLs ranged from 3.4% to 88.2%. Total PVE of the M-QTLs for each trait was significantly higher than that of the E-QTLs. The total number of M-QTLs identified in the IP/DS//IP population was higher than in the IP/DS//DS population. However, the total PVE by the M-QTLs and E-QTLs together for each trait was similar in the two populations, suggesting that the two $BC_1F_1$ populations are equally useful for QTL analysis. Maps and QTLs in the two populations were compared. Eleven new QTLs were identified for SN, SF, GL, and GW in this study, and they will be valuable in marker-assisted selection, particularly for improving grain traits in tongil-type varieties.

• Journal of Digital Contents Society
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• v.11 no.4
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• pp.433-443
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• 2010

In this paper, we provide a comprehensive overview and classification on a wide range of the existing location management schemes which have been reported for wireless cellular networks and Mobile IP-based networks, respectively. In addition, from the various previous literature, we derive common key conceptual techniques, their main design goals and performance considerations on them, which can provide a useful guidance for understanding location management schemes regardless of network types. The aim of this paper is not to propose a new scheme for location management, but to highlight the various key design features involved in the design of the existing location management schemes, and to enhance an insight into the fundamental principles and techniques for designing more efficient and optimized location management scheme in future wireless mobile networks. We expect that regardless of network types, these underlying fundamental principles and conceptual techniques could be also easily tailored for more efficient mobility/QoS support in future mobile computing environments.

• The Journal of the Korea Contents Association
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• v.3 no.2
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• pp.65-72
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• 2003

In this paper, the new scheme using a Combined Cache(CC) that combing the Paging and Routing Cache(PRC) and an alternative handoff method according to the type of data transmission for achieving the efficient realtime communication. The PRC and quasi-soft handoff method reduce the path duplication. But they increase the network traffic load because of the handoff state packet of Mobile Host(MH). Moreover the use the same handoff method without differentiating the type of transmission data. Those problems are solved by operating U with a semi-soft handoff method for realtime data transmission and with a hard handoff method for non-realtime data transmission. As a result or simulation a better performance is obtained because of the reduction of the number of control packet in case that the number of cells are below 20. And the packet arrival time and loss of packet decreased significantly for realtime data transmission.

• Korean Journal of Veterinary Research
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• v.33 no.3
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• pp.407-417
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• 1993

Bupleurum falcatum has been used for treatment of inflammation, jaundice, influenza and hepatitis as a traditional orient folk medicine. This experiment was carried out to evaluate the effect of B falcatum extract on cellular immune responses in vivo and in vitro. Antigen binding cell(ABC) assay, antibody production, Arthus and delayed-type hypersensitivity(DTH) reaction against sheep erythrocytes(SRBC) were very depressed in B falcatum extract treated group in vivo. The growth of Staphylococcus aureus in brain heart infusion(BHI) broth containing B falcatum extract was remarkably inhibited. Otherwise, that of Salmonella typhyimurium was not significantly increased in vitro. When B falcatum extract pretreated mice were intraperitoneally(IP) injected S typhimurium and S aureus, respectively, the number of bacteria in peritoneal exudates were time dependent declination compared with those of control, and the weight of spleen and the number of macrophage migration into peritoneal cavity have no difference from those of untreated control. B falcatum extract gradually increased phagocytic activities of peritoneal macrophage against Candida albicans time and dose dependently, and was not significant production of migration inhibiotory factor(MIF). But migration abilities of normal leucocytes in B falcatum extract pretreated group were decreased dose dependently. When B falcatum extract was IP administered, these data indicate that B falcatum extract increases level of serum coticosterone. Therefore, B falcatum extract was indirectly mediated in immune system by serum coticosterone having relation to immunosuppression. These results lead to the conclusion that B falcatum extract acts as a trigger or regulator of cellular immune responses in immune system.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.12
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• pp.54-62
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• 2007

Mobile IPv6 is the representative standard protocol proposed to offer mobility of mobile hosts, but it has drawbacks such as high handover latency and packet loss during handover. To complement these drawbacks, several protocols have been proposed and they can support faster handover than the Mobile IPv6, but there still exists inevitable packet loss during handover in those protocols. In this paper, we propose a new handover procedure of mobile host who has a dual link for minimizing packet loss rate during micro handover to improve mobility capability of Cellular Ethernet system that supports mobility at layer 2. And we derive the superiority of proposed scheme by comparing in terms of packet loss rate, handover latency and throughput of proposed scheme with those of Hierarchical Mobile IPv6 which is the representative IP-layer micro mobility protocol by simulation.