• KSBB Journal
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• v.4 no.1
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• pp.11-14
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• 1989

A study on the continuous fermentation with cell recycle by a tower fermentor to produce ethanol has been carried out. ethanol fermentation was conducted with flocculating yeast strain, Saccharomyces cerevisiae TS4, to compare the ethanol productivity with conventional continuous process. Employing a 15% glucose feed, a cell density of 50 g/l was obtaind. The ethanol productivity of the cell recycle system was found to be 26.5g EtOH/1-hr, which was nearly 7.5 times higher than the conventional continuous process without cell recycle. A cell recycle ratio of 7 to 8 resulted in the highest ethanol productivity and cell concentration. Thus the cell recycle ratio was found to be a key factor in controlling the production of clarified overflow liquid. An aeration rate above 3.8 $\times$ 10-3 VVM seemed to decrease the ethanol productivity. The continuous fermentation with cell recycle was successfully used in the separation of cells from fermentation broth with enhancement of mixing in the tower fermentor.

• Journal of the Korean Society of Industry Convergence
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• v.7 no.4
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• pp.383-389
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• 2004

This paper is to develop the program for sizing of a counter-flow cooling tower. Air flow, air exit tmperature, fan power are calculated from design coditions of cooling tower by using this program. The basic equations and solutions of the heat transfer and pressure drop of cooling tower are descrived and the algorithm development for design of cooling tower is performed. The variation of fan power of cooling tower in acoording to variation of cell area and fill height is performed by using this program. This result shows that the optimal design for install and running cost of cooling tower can be performed by using this program.

• Journal of the Korea Safety Management & Science
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• v.15 no.3
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• pp.143-150
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• 2013

A cell site lease is a legal agreement by which the owner of a building or a piece of land allows a wireless carrier to use part of it for a cell tower for a period of time in return for money. Wireless carriers spend significant money for cell site leases. This paper tries to find factors affecting cell site leases and management solutions to save lease costs. In other words, this research identifies any factor influencing cell site leases among age, gender, and geographical area in the first problem and determines management priorities using an importance-satisfaction model in the second problem. This paper can provide wireless carriers with effective decision making tools and a basis for negotiation of cell site leases, as they do not have enough bases for negotiation.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.7
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• pp.2953-2958
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• 2015

Although associations between thioredoxin interacting protein (TXNIP) and cancers have been recognized, the effects of TXNIP on non-small cell lung cancer (NSCLC) prognosis remained to be determined in detail. In addition, while hypoxia is a key characteristic of tumor cell growth microenvironment, the effect of hypoxia on TXNIP expression is controversial. In this study, formaldehyde fixed and paraffin embedded (FFPE) samples of 70 NSCLC patients who underwent resection between January 2010 and December 2011 were obtained. Evaluation of TXNIP and hypoxia inducible factor-$1{\alpha}$ ($HIF-1{\alpha}$) protein expression in FFPE samples was made by immunohistochemistry. By Kaplan-Meier method, patients with high TXNIP expression demonstrated a significantly shorter progression free survival (PFS) compared with those with low TXNIP expression (18.0 months, 95%CI: 11.7, 24.3 versus 23.0 months, 95%CI: 17.6, 28.4, P=0.02). High TXNIP expression level was also identified as an independent prognostic factor by Cox regression analysis (adjusted hazard ratio: 2.46; 95%CI: 1.08, 5.56; P=0.03). Furthermore, TXNIP expression was found to be significantly correlated with $HIF-1{\alpha}$ expression (Spearman correlation=0.67, P=0.000). To further confirm correlations, we established a tumor cell hypoxic culture model. Expression of TXNIP was up-regulated in all three NSCLC cell lines (A549, SPC-A1, and H1299) under hypoxic conditions. This study suggests that hypoxia induces increased TXNIP expression in NSCLC and high TXNIP expression could be a poor prognostic marker.

• 한국정보통신설비학회:학술대회논문집
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• 2003.08a
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• pp.143-148
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• 2003

In this paper, we focused on the performance of reverse link in 1.8GHz CDMA 1x system including the Tower-Mount LNA in an urban environment. In order to study the benefit of TMLNA, Hata model is used and the effects of multiple cells are considered. Cell coverage extension ratio is proportional to the increased gain of TMLNA in CDMA cell site. However the cell coverage is not extended even if the noise figure of TMLNA is reduced in an urban area. When typical RSSI is between -70dBm and -80dBm, the increased gain and the reduced NF of TMLNA are not impact to the pole capacity of cell site. Namely, the benefit of TMLNA in an urban area is not the problem of capacity but the proble of sensitivity. The results are also shown that reverse link $E_b/N_o$ is improved by minimum 5dB and BER is lower than $10^{-6}$.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.139-143
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• 2014

Although correlations between platelets and lung cancer has been recognized, effects on non-small cell lung cancer (NSCLC) metastasis remain to be determined in detail. In the present study, wound healing assays revealed a role of platelets in NSCLC cell migration. Thus the mean migration rate of lung adenocarcinoma A549 cells was significantly elevated after co-culture with platelets ($81.7{\pm}0.45%$ vs $41.0{\pm}3.50%$, P<0.01). Expression of GAPDH was examined by reverse transcription-polymerase chain reaction to study the effect of platelets on NSCLC cell proliferation. The result showed that the proliferation of A549 and SPC-A1 cells was not affected. Mouse models were established by transfusing A549 cells and SPC-A1 cells into mice lateral tail veins. We found tumor metastasis nodules in lungs to be increased significantly after co-transfusion with platelets (in A549, $4.33{\pm}0.33$ vs $0.33{\pm}0.33$, P=0.01; in SPC-A1, $2.67{\pm}0.33$ vs $0.00{\pm}0.00$, P=0.01). In addition, consecutive inoperable patients with newly diagnosed NSCLC (TNM stage III or IV) between January 2009 and December 2011 were retrospectively reviewed. Using the Kaplan-Meier method, NSCLC patients with a high platelet counts demonstrated a significantly shorter progression free survival compared with those with a low platelet count (> $200{\times}10^9/L$, 3 months versus ${\leq}200{\times}10^9/L$, 5 months, P=0.001). An elevated platelet count was also identified as an independent prognostic factor by Cox regression analysis for prgression free survival (adjusted hazard ratio: 1.69; 95% CI: 1.16, 2.46; P=0.006). This study suggested that platelets might contribute to the hematogenous metastatic process by promoting cancer cell migration, which eventually affects the prognosis of NSCLC.

• Microbiology and Biotechnology Letters
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• v.20 no.5
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• pp.607-613
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• 1992

A tower fermentor equipped with a modified settler was used for ethanol fermentation using highly flocculating yeast, Saccharomyces uvarum. The settler was constructed of glass column divided into two chambers by a funnel shaped divider. Gas was allowed to escape from lower chamber of the settler through a small tube. This design significantly reduced the turbulence in upper chamber of the settler and made it possible to operate at high dilution rate. Using the tower fermentor, the effects of operating conditions such as initial glucose concentration, dilution rate and cell recycle ratio were studied. The maximum ethanol productivity, 64.0 g/l' h was obtained at a dilution rate 1.1 h -1 and a cell recycle ratio 5 with the corresponding ethanol concentration of 58.8 g/l, and cell mass of 88 g/l.

• Wind and Structures
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• v.34 no.2
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• pp.199-213
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• 2022

The current study investigates the dynamic effects in the tornado-structure response of an aeroelastic self-supported lattice transmission tower model tested under laboratory simulated tornado-like vortices. The aeroelastic model is designed for a geometric scale of 1:65 and tested under scaled down tornadoes in the Wind Engineering, Energy and Environment (WindEEE) Research Institute. The simulated tornadoes have a similar length scale of 1:65 compared to the full-scale. An extensive experimental parametric study is conducted by offsetting the stationary tornado center with respect to the aeroelastic model. Such aeroelastic testing of a transmission tower under laboratory tornadoes is not reported in the literature. A multiaxial load cell is mounted underneath the base plate to measure the base shear forces and overturning moments applied to the model in three perpendicular directions. A three-axis accelerometer is mounted at the level of the second cross-arm to measure response accelerations to evaluate the natural frequencies through a free-vibration test. Radial, tangential, and axial velocity components of the tornado wind field are measured using cobra probes. Sensitivity analyses are conducted to assess the variation of the structural dynamic response associated with the location of the tornado relative to the lattice transmission tower. Three different layouts representing the change in the orientation of the tower model relative to the components of the tornado-induced loads are considered. The structural responses of the aeroelastic model in terms of base shear forces, overturning moments, and lateral accelerations are measured. The results are utilized to understand the dynamic response of self-supported transmission towers to the tornado-induced loads.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.12
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• pp.1395-1401
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• 2014

In an effort to develop and implement an inertial balance with high performance, the response characteristics of a load cell, which are some of the critical parameters for optimal system design, were evaluated using a sample object of approximately 100 g under microgravity conditions. To this end, a 15-m drop-tower was used to produce microgravity conditions, and the response characteristics of the load cell were investigated in terms of the variations in the magnitude of the deceleration of the sample object, noting that the mass of a living animal should be determined in microgravity. An analysis of the ratio of the inertial forces clearly demonstrated that the average velocity of a load cell plate should be higher than 0.5 m/s to meet the design requirements.

• Journal of the Korean Solar Energy Society
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• v.24 no.4
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• pp.27-33
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• 2004

Mechanical load measurements on blade and tower of Vestas 100 kW wind turbine has been reformed in Wollyong test site, Jeju island. The experimental procedure for the measurement of wind turbine loads, such as edgewise(lead-lag) bending moment, flapwise bending moment, and tower base bending moment, has been established. The test facilities consisting of strain-gauges, telemetry and T-Mon system are installed in the wind turbine. Strain gauges are on-site calibrated against load cell prior to monitoring the wind turbine loads. Using the test setup, the loads on the components are being measured and analysed for various external conditions of the wind turbine. A set of results for near rated wind speed has been presented in this paper.