• Title/Summary/Keyword: Cell size and density

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A Study on Anti-oxidative Effect of Electroacupuncture at Kokchi($LI_{11}$) in Rats (곡지(곡지)에 시술(施術)한 저주파 전침자극(電鍼刺戟)의 항산화(抗酸化) 효과(效果)에 대(對)한 실험적(實驗的) 연구(硏究)량)

  • Park, Choon-Eul;Kim, Young-Il;Yim, Yun-Kyoung
    • Journal of Acupuncture Research
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    • v.24 no.3
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    • pp.81-97
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    • 2007
  • Objectives: The purpose of this study is to investigate the anti-oxidative effect of electroacupuncture at Kokchi($LI_{11}$) in rats. Methods: A study administer AAPH to the abdominal cavity of rats and stimulate Kokchi($LI_{11}$) of the rat that lead to oxidative stress by electropuncture. And the study survey serum albumin, total bilirubin, LDL-cholesterol, LDH, Glucose, GOT, GPT and measure SOD activity, GSH concentration, catalase activity, NO concentration, MDA concentration. Results: 1. At the analysis of blood chemistry Albumin and Glucose significantly increase at $LI_{11}$-NR group, $LI_{11}$-EA group than at control group and holder group. LDL cholesterol, GOT, GPT decrease meaningfully. 2. As results of measurement at liver, SOD, Catalase represnet significantly increase at $LI_{11}$-NR group and $LI_{11}$-EA group than at control group and holder group. 3. Glutathione has some increases at the $LI_{11}$-NR group and $LI_{11}$-EA group than at the control group and the holder group. 4. As a result of measurement of NO and MDA's content, the content of NO decrease at the $LI_{11}$-NR group than at the control group. That reduces more meaningfully at the $LI_{11}$-EA group than at the control group. MDA has a significant decrease at the $LI_{11}$-NR group and the $LI_{11}$-EA group. 5. At the histological analysis, the study confirm that the density of intracellular cytoplasm in the liver tissue decreases at the control group as compared with the Normal group and the size of cell increases. Conclusions : These results suppose that electroacupuncture at $LI_{11}$ has an anti-oxidant effect in human.

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Studies on the Physical and Mechanical Properties of Imported and Domestic Corks (수입(輸入)코르크와 국산(國産)코르크의 물리(物理)·기계적(機械的) 성질(性質)에 관(關)한 연구(硏究))

  • Kim, Byung-Ro
    • Journal of the Korean Wood Science and Technology
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    • v.21 no.4
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    • pp.45-54
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    • 1993
  • This study examines the differences in structures, physical and mechanical properties between domestic(Quercus variabilis Blume) and foreign(Quercus suber L.) corks. The results obtained are as follows: 1. The cork tissue consists of cork cells, lenticels, sclereids and dark-brown zone. There was a significant difference in ratio of cork cells between foreign cork(93 %) and domestic cork(87 %). The ring width and width of late cork of the foreign cork were wider than those of domestic cork. But the percentage of late cork of domestic cork was richer than that of foreign cork. The size of cork cell of foreign cork was larger by about two times than that of domestic cork. 2. The density was slightly higher in domestic cork(0.22 g/$cm^3$) than in foreign cork(0.19 g/$cm^3$). During first 24 hours, the amount of water absorption of the foreign cork was greater than that of domestic cork. However, after 24 hours, the tendency was reversed. The level of EMC was higher in domestic cork than in foreign cork. Total shrinkage in the radial and tangential directions was larger in domestic cork than tn foreign cork. In the longitudinal direction, the tendency was reversed. There was no difference in total swelling in three woody directions between the two corks. 3. The modulus of elasticity in compression in the logitudinal and tangential direction was higher in domestic cork than in foreign cork, but the tendency was reversed in the radial direction. Both corks showed 95% of recovery rate after 24 hours when they were compressed by 0.5. There were no differences in tension strength and Brinell,s hardness bet ween domestic and foreign corks.

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4-Chloro-2-Isopropyl-5-Methylphenol Exhibits Antimicrobial and Adjuvant Activity against Methicillin-Resistant Staphylococcus aureus

  • Kim, Byung Chan;Kim, Hyerim;Lee, Hye Soo;Kim, Su Hyun;Cho, Do-Hyun;Jung, Hee Ju;Bhatia, Shashi Kant;Yune, Philip S.;Joo, Hwang-Soo;Kim, Jae-Seok;Kim, Wooseong;Yang, Yung-Hun
    • Journal of Microbiology and Biotechnology
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    • v.32 no.6
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    • pp.730-739
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    • 2022
  • Methicillin-resistant Staphylococcus aureus (MRSA) causes severe infections and poses a global healthcare challenge. The utilization of novel molecules which confer synergistical effects to existing MRSA-directed antibiotics is one of the well-accepted strategies in lieu of de novo development of new antibiotics. Thymol is a key component of the essential oil of plants in the Thymus and Origanum genera. Despite the absence of antimicrobial potency, thymol is known to inhibit MRSA biofilm formation. However, the anti-MRSA activity of thymol analogs is not well characterized. Here, we assessed the antimicrobial activity of several thymol derivatives and found that 4-chloro-2-isopropyl-5-methylphenol (chlorothymol) has antimicrobial activity against MRSA and in addition it also prevents biofilm formation. Chlorothymol inhibited staphyloxanthin production, slowed MRSA motility, and altered bacterial cell density and size. This compound also showed a synergistic antimicrobial activity with oxacillin against highly resistant S. aureus clinical isolates and biofilms associated with these isolates. Our results demonstrate that chlorinated thymol derivatives should be considered as a new lead compound in anti-MRSA therapeutics.

Evaluation on Effects of Composting and Pelleting on Nutritional Composition of Broiler Litter and Feasibility of Use of a Small-scale Pelletizer (호기발효와 펠렛 처리가 육계분의 사료영양적 성분에 미치는 영향 및 소형 펠렛기의 육계분 성형 가능성 평가)

  • 곽완섭
    • Journal of Animal Environmental Science
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    • v.8 no.3
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    • pp.191-198
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    • 2002
  • This study was conducted to determine changes in internal temperature and chemical composition during the composting of broiler litter(BL) and to evaluate the feasibility of use of a small-scale pelletizer for the pelleting of composted BL. BL was composted for 4 weeks in an wooden cell with a size of 1 m length $\times$ 1 m width $\times$ 1.2 m height. Internal temperature reached to peak(68$^{\circ}C$) at the fourth day and thereafter gradually reduced. Among chemical components in BL, composting reduced organic matter content and increased dry matter and indigestible protein(ADF-CP) contents. When BL was pelleted using an economical small-scale pelletizer, the proper die diameter was 8~18 mm and the proper moisture content of composted BL was 20~25%. Beyond these proper conditions, addition of heat and pressure or pellet aids may be necessary. Pelleting of BL resulted in nearly threefold increase of bulk density, significant moisture evaporation, and little change in chemical components except for increased indigestible protein. In conclusion, BL may be converted into a feed with low to medium nutrition by the composting and pelleting process.

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Morphological study on effect of radiation in developing mouse brain after fetal exposure (태아시기의 방사선 노출에 의한 마우스 뇌 발달에 미치는 영향에 관한 형태학적 연구)

  • Lee, Jong-hwan;Oh, Heon;Kim, Se-ra;Lee, Hae-june;Kim, Tae-hwan;Lee, Yun-sil;Kim, Sung-ho
    • Korean Journal of Veterinary Research
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    • v.41 no.3
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    • pp.395-400
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    • 2001
  • The present study analyze the morphological aspects of the cerebrum of mice with prenatal exposure to high and low dose (0.5, 1, 2 Gy) of $\gamma$-radiation on gestation day 12 or 16. The animal were allowed to give birth and the offspring were sacrificed at postnatal days 28 for gross and microscopic examination of cerebrum. Their body weight, brain weight, brain length, brain width, cortical thickness and area of cingulum bundle were examined. The histological and planimetric analysis were performed observing coronal sections. The gross malfomation (microcephaly) and abnormality of cortical architecture were prominent after exposure to 2 Gy on day 12 of gestation. significant dose-related reductions in body weight, brain weight, brain size were found in all irradiated groups. A significant change was found in thickness of the cerebral cortex and area of the cingulum bundle in the groups exposed to 0.5 Gy or more. There was no difference a lamina patter of six layers in cerebral cortex between the control and irradiated groups, but cell packing density increased significantly in the group exposed to 1 Gy or more. These results suggested that dose as low as 0.5 Gy could cause a morphologically reduce change in developing mouse cerebrum and exposure on day 12 of gestation to $\gamma$-irradiation is a particularly sensitive phase in causing malformation and abnormality of central nerve system.

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Ferroelectric-gate Field Effect Transistor Based Nonvolatile Memory Devices Using Silicon Nanowire Conducting Channel

  • Van, Ngoc Huynh;Lee, Jae-Hyun;Sohn, Jung-Inn;Cha, Seung-Nam;Hwang, Dong-Mok;Kim, Jong-Min;Kang, Dae-Joon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.427-427
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    • 2012
  • Ferroelectric-gate field effect transistor based memory using a nanowire as a conducting channel offers exceptional advantages over conventional memory devices, like small cell size, low-voltage operation, low power consumption, fast programming/erase speed and non-volatility. We successfully fabricated ferroelectric nonvolatile memory devices using both n-type and p-type Si nanowires coated with organic ferroelectric poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] via a low temperature fabrication process. The devices performance was carefully characterized in terms of their electrical transport, retention time and endurance test. Our p-type Si NW ferroelectric memory devices exhibit excellent memory characteristics with a large modulation in channel conductance between ON and OFF states exceeding $10^5$; long retention time of over $5{\times}10^4$ sec and high endurance of over 105 programming cycles while maintaining ON/OFF ratio higher $10^3$. This result offers a viable way to fabricate a high performance high-density nonvolatile memory device using a low temperature fabrication processing technique, which makes it suitable for flexible electronics.

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Anti-hyperlipidemic activity of Rhynchosia nulubilis seeds pickled with brown rice vinegar in mice fed a high-fat diet

  • Park, Ki-Moon;Lee, Seung Ho
    • Nutrition Research and Practice
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    • v.7 no.6
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    • pp.453-459
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    • 2013
  • The abnormal content of blood lipids often results in metabolic diseases, such as hyperlipidemia and obesity. Many agents, including natural sources from traditional food, have been developed to regulate the blood lipid contents. In this study, we examined the anti-hyperlipidemic activity of Rhynchosia nulubilis seeds pickled with brown rice vinegar (RNSpBRV), a Korean traditional pickled soybean food. Since RNSpBRV is made of R. nulubilis seeds (RNS) soaked in brown rice vinegar (BRV), we compared the anti-adipogenic activity between RNS, BRV and solid fraction of RNSpBRV (SF-RNSpBRV), liquid fraction of RNSpBRV (LF-RNSpBRV). For this, the inhibitory effect of lipid accumulation in 3T3-L1 adipocyte was checked by adding methanol extracts of mixed RNS and BRV, LF-RNSpBRV, and SF-RNSpBRV. The addition of each methanol extract up to 1 mg/ml showed no cytotoxicity on 3T3-L1 adipocyte, and approximately 20% of the lipid droplet formation was suppressed with the methanol extract of BRL or SF-RNSpBRV. The highest suppression (42.1%) was achieved with LF-RNSpBRV. In addition, mice fed a high fat diet (HFD) supplemented with 5% RNSpBRV powder led to increased high density lipoprotein (HDL) cholesterol and lower blood glucose, triglyceride, and total cholesterol compared to mice fed with a HFD diet only. Interestingly, the size of the epididymis cells gradually decreased in HFD + 1% RNSpBRV and HFD + 5% RNSpBRV-fed mice if compared those of HFD-fed mice. Taken together, these results provide evidence that RNSpBRV has a regulatory role in lipid metabolism that is related to hyperlipidemia.

A study onthe modeling of broadband access network for national information infrastructure and numerical analysis of its economics (초고속 액세스 망의 모델화 및 경제성에 대한 검토)

  • 정해원;박기식;노장래;조성준
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.22 no.12
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    • pp.2806-2818
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    • 1997
  • It is generallyaccepted that broadband access technologies will play an important role in the National Information Infrastructure. However, the provision of direct fibers to residential and small business customers has always been considered a challenge. To accelerage the provision of Broadband Access Facilities, alternatibe paths could be identified and actaivated in parallel. In this paepr, we present an overview of the alternative access technologies focusing on xDSL, FTTx, HFC, HFR, and suggest the modeling of the access netetwork systems which is using of the technologies. Also to investigate the economics of each access systems, we derve the numerical equations which is summed up the al parameter including the labor cost of the model system. The proposed equation has a variable which is the cell size (or subsciber clusters) and calculate the real cost values which is normalized by the copper cable unit cost. From the numerical resutls, we conclude that the economic access method to provide these broadband capabilities is depended on the subscriber penetration, the patterns of subscriber distribution density and existing communication infrastructures. It can be expected that our analytical model and equations provides an elegant solution to choose the optimal broadband access technologies to residential and small business customers.

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A Design of LDPC Decoder for IEEE 802.11n Wireless LAN (IEEE 802.11n 무선 랜 표준용 LDPC 복호기 설계)

  • Jung, Sang-Hyeok;Shin, Kyung-Wook
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.47 no.5
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    • pp.31-40
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    • 2010
  • This paper describes a LDPC decoder for IEEE 802.11n wireless LAN standard. The designed processor supports parity check matrix for block length of 1,944 and code rate of 1/2 in IEEE 802.11n standard. To reduce hardware complexity, the min-sum algorithm and layered decoding architecture are adopted. A novel memory reduction technique suitable for min-sum algorithm was devised, and our design reduces memory size to 25% of conventional method. The LDPC decoder processor synthesized with a $0.35-{\mu}m$ CMOS cell library has 200,400 gates and memory of 19,400 bits, and the estimated throughput is about 135 Mbps at 80 MHz@2.5v. The designed processor is verified by FPGA implementation and BER evaluation to validate the usefulness as a LDPC decoder.

Microspore-derived Embryo Formation and Morphological Changes during the Isolated Microspore Culture of Radish (Raphanus sativus L.)

  • Han, NaRae;Kim, Sung Un;Park, Han Young;Na, Haeyoung
    • Horticultural Science & Technology
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    • v.32 no.3
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    • pp.382-389
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    • 2014
  • Raphanus sativus L. cv. Taebaek, a efficiently microspore-derived embryo (MDE)-forming cultivar, and 'Chungwoon', a non-MDE-forming cultivar were selected as donor plants for isolated microspore culture. Radish flower bud of 2.0 (small, S), 4.0 (medium, M), and 6.0 (large, L) ${\pm}$ 0.5 mm in length were isolated to determine the temporal relationship between flower bud size and MED yield. Anatomical observations revealed no difference in the structure of the flower buds between the two cultivars. In both cultivars, the stigmas were much longer than the floral leaf in M-sized flower buds. The MDE yields for 'Taebaek' per petri dish were 6.6 and 1.3 for M- and L-sized of flower buds, respectively, but MDE formation was not induced in the S flower buds. On the other hand, 'Chungwoon' failed to form MDEs in all flower buds. The microspore density of 'Taebaek' was 1.3 times more than that of 'Chungwoon' for M sized flower buds. Of the M-sized buds from 'Taebaek' and 'Chungwoon', 92.1 and 81.6%, respectively, were in the late uninucleate microspore stage, which is characterized by the highest frequency of MDE formation. Anatomical observations of MDE formation revealed that the microspores were able to divide to form a primordium from which cell division took place continuously in the 'Teabeak' cultivar. However, the microspores of 'Chungwoon' failed to progress beyond the primodium stage, resulting in lack of MDE formation. By contrast, after the formation of the primordium, various developmental stages of embyos from microspore were observed in the 'Taebaek' cultivar. These results can be used to determine MDE forming potentials of radish cultivars.