• 제목/요약/키워드: Cell injection

검색결과 1,324건 처리시간 0.029초

사출법으로 제조된 자동차 내장부품의 표면특성 개선 연구 (Improved Surface Characteristics of Automotive Interior Parts Fabricated by Injection Molding Method)

  • 최동혁;황현태;손동일;김대일
    • 한국표면공학회지
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    • 제52권1호
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    • pp.43-51
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    • 2019
  • The environmental pollution which is global warming and abnormal climate is caused by increasing population and activated economics. To reduce environmental pollution, we have being efforts into reducing $CO_2$ emission and use of energy, resources. Especially, for the sake of light weight and fuel efficiency of automotive industry, many countries have defined the restrict environmental regulation which stipulate high magnitude of reducing $CO_2$ emission. In this study, we have predicted the problem of Mu-cell injection molding through the finite element analysis as a function of temperature controlled by Joule heating or in terms of mold temperature. From the result of finite element analysis, we have determined the optimized process and made the injection mold included electric current heating system with Mu-cell manufacturing. Lastly, we analyzed the surface characteristics of the injection products with mold temperature.

SONOS 구조를 갖는 멀티 비트 소자의 프로그래밍 특성 (Programming Characteristics of the Multi-bit Devices Based on SONOS Structure)

  • 김주연
    • 한국전기전자재료학회논문지
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    • 제16권9호
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    • pp.771-774
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    • 2003
  • In this paper, the programming characteristics of the multi-bit devices based on SONOS structure are investigated. Our devices have been fabricated by 0.35 $\mu\textrm{m}$ complementary metal-oxide-semiconductor (CMOS) process with LOCOS isolation. In order to achieve the multi-bit operation per cell, charges must be locally frapped in the nitride layer above the channel near the source-drain junction. Programming method is selected by Channel Hot Electron (CUE) injection which is available for localized trap in nitride film. To demonstrate CHE injection, substrate current (Isub) and one-shot programming curve are investigated. The multi-bit operation which stores two-bit per cell is investigated. Also, Hot Hole(HH) injection for fast erasing is used. The fabricated SONOS devices have ultra-thinner gate dielectrics and then have lower programming voltage, simpler process and better scalability compared to any other multi-bit storage Flash memory. Our programming characteristics are shown to be the most promising for the multi-bit flash memory.

CAE 성형해석 데이터의 사출금형 설계 활용 방법에 관한 연구 (A study on the injection mold design application method of CAE mold analysis data)

  • 남승돈
    • Design & Manufacturing
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    • 제13권3호
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    • pp.29-34
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    • 2019
  • Cell phone injection is characterized by its small size and thinness. In addition, the product has a short cycle time, requiring a very short production schedule. To produce more accurate products faster, data from experience in producing similar products is required. In this study, two mobile phone models are presented. In this study, the quality problems caused by molding analysis and actual injection molding were analyzed and made into a database. As a result, it was considered that all the defects in the molding analysis do not affect the product in some cases, rather than appear as defects in the actual product. All defects shown in the molding analysis can be made into a database, and based on this data, it will be possible to obtain an effect that can predict more accurately whether it will cause problems after injection.

로드셀과 자이로센서를 융합한 수액 감지 시스템 설계 및 오차 검증 (Design and Error Verification of Intravenous Injection Detection System that Combines Load Cell and Gyro Sensor)

  • 김선칠
    • 한국융합학회논문지
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    • 제12권1호
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    • pp.127-132
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    • 2021
  • 의료기관에서 사용되는 수액 모니터링 시스템은 원격으로 환자에게 투입된 수액량과 투여의 종료시점 정보를 제공하기 위해서 개발되었다. 수액 투입량을 측정하기 위해서는 수액 내부에서 외부로 나가는 정량을 무게로 혹은 유량을 측정센서로 측정할 수 있다. 여기에 적용되는 장치의 기준은 정확성, 경계성이다. 또한 소형으로 환자에게 수액 설치시 사용에 용이해야 한다. 의료기관에서는 측정값의 정확도가 높아야 하며, 경제적으로 저가의 장치를 요구하고 있다. 본 연구에서는 저가의 소형 무게 중심 로드셀 센서를 적용하였으며, 측정값의 정확도를 위해 자이로센서와 융합하여 외부 움직임에 의한 아트펙트를 줄이는 알고리즘을 적용하였다. 그 결과 측정의 오차를 줄일 수 있어 수액 모니터링 측정값의 정확도를 향상시키는 효과를 확인하였다.

Real-Time Force Sensing in the Envelope of Zebrafish Egg during Micropipette Penetration

  • Yun, Seok;Kim, Deok-Ho;Kim, Byung-Kyu;Lee, Sang-Ho;Park, Gwi-Tae
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2003년도 ICCAS
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    • pp.2451-2456
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    • 2003
  • In biological cell manipulation, manual thrust or penetration of an injection pipette into an egg is currently performed by a skilled operator, relying only on visual feedback information. Massive load of various micro injection of either genes, fluid or cells in the postgenomic era calls a more reliable and automatic micro injection system that can test hundreds of genes or cell types at a single experiment. We initiated to study cellular force sensing in zebrafish eggs as the first step for the development of a more controllable micro injection system by any inexperienced operator. Zebrafish eggs at different developmental stages were collected and an integrated biomanipulation system was employed to measure cellular force during penetrating the egg envelope, the chorion. First of all, the biomanipulation system integrated with cellular force sensing instrument is implemented to measure the penetration force of cell membranes and characterize mechanical properties of zebrafish embryo cells. Furthermore, implementation of cellular force sensing system and calibration are presented. Finally, the cellular force sensing of penetrating cell membranes at each developmental stages was experimentally performed. The results demonstrated that the biomanipulation system with force sensing capability can measure cellular force at real-time while the injection operation is undergoing. The magnitude of the measured force was in the range of several hundreds of uN. The precise real-time measurement should provide the first step forwards for the development of an automatic and reliable injection system of various materials into biological cells.

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Allyl Isothiocyanate 유발 피부염에 의한 척수후각세포의 활동성 변동 (Modification in the Responsiveness of Dorsal Horn Cells during Allyl Isothiocyanate-Induced Inflammation in the Cat)

  • 윤영복;김진혁;신홍기;김기순
    • The Korean Journal of Physiology
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    • 제24권2호
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    • pp.305-317
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    • 1990
  • The present study was performed to investigate modification in the electrophysiological characteristics of cat dorsal horn cells during neurogenic inflammation induced by mustard oil. The results obtained were summarized as follows: 1) Following subcutaneous injection of mustard oil the majority of wide dynamic range (WDR) cells (10/15 units) showed enhanced responses (80%) to brush, while the responses to all types of mechanical stiumli were enhanced in 3/15 units. One cell was further activated by pinch and the another was not affected at all after induction of inflammation. 2) The sensitization of WDR cell was resulted from subcutaneous injection of mustard oil either inside or outside of the receptive field (RF), whereas the spontaneous activity increased only after mustard oil was injected inside of the RF. 3) In the animal with inflammation the responses of high threshold (HT) cell to noxious stimulus were not altered, while HT cell responded to such mechanical stimulus as pressure which was usually ineffective in normal animals. 4) After induction of inflammation, low threshold (LT) cell appeared to be converted to WDR cell, showing responses not only to brush but also to pressure and pinch. 5) The mustard oil-induced inflammation enhanced responses of WDR and HT cells to the thermal stimuli and also resulted in a pronounced after-discharge in WDR cells. 6) After subcutaneous injection of lidocaine, the increased background activity of WDR cells due to inflammation was almost completely abolished. 7) A subcutaneous injection of mustard oil inside of the RF invariably desensitized the dorsal horn cells which receive sensory inputs from the inflamed RF. From the results of Present study it was revealed that a neurogenic inflammation induced by mustard oil resulted in an enhancement of responses of cat dorsal horn cells to mechanical and thermal stimuli.

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초박형(0.3t) 도광판 적용을 위한 유압식 고속사출성형의 성형 안정성 연구 (A study on the Molding Stability of Hydro-mechanical High Speed Injection Molding for Thin-Walled(0.3mm) LGP)

  • 김종선;오정길;정철;안희정;황철진;김종덕;윤경환
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2008년도 추계학술대회 논문집
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    • pp.422-425
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    • 2008
  • Recently, electronic products and related parts are required to have thin thickness because of small form factor. To go with the trend, LGP(light guide plate) of LCD BLU(Liquid Crystal Display Back light unit: It is one of kernel parts of LCD) for cell phone has the thickness of 0.3 mm and the battery case of cell phone has 0.25 mm. Accordingly, high speed injection molding is required to make products which have thin thickness. High speed injection molding means that the resin is injected into the cavity at higher than normal speed avoiding short shot. In the case of hydro-mechanical high speed injection machine, it requires the design for hydraulic unit to make high injection speed and the design for control unit to control hydraulic unit. In the present paper, we concentrated on the molding stability of hydro-mechanical high speed injection machine to make an LGP of 0.3 mm thickness.

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박판(0.3mm) 도광판 성형을 위한 유압식 고속사출성형의 성형 안정성 연구 (Molding Stability of Hydro-Mechanical High Speed Injection Molding for Thin-Wall(0.3mm) LGP)

  • 황철진;김종선;오정길;정철;안희정;허영무;김종덕;윤경환
    • 소성∙가공
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    • 제17권8호
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    • pp.657-661
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    • 2008
  • Recently, products of electronic industry and related parts are required to have the thickness thinner and thinner to reduce the part weight. To go with this trend, LGP(light guide plate) of LCD-BLU(Liquid Crystal Display-Back Light Unit: It is one of kernel parts of LCD) for cell phone has the thickness of ${\sim}0.3mm$ and the battery case of cell phone has ${\sim}0.25mm$. Accordingly, high speed injection molding is required to mold products which have thinner parts. To achieve high speed injection and proper control of hydraulic unit, various design was applied to conventional injection unit. In the present paper, we concentrated on the molding stability of hydro-mechanical high speed injection machine to make an LGP of 0.3mm thickness.

In Vivo Spinal Distribution of Cy5.5 Fluorescent Dye after Injection via the Lateral Ventricle and Cisterna Magna in Rat Model

  • Lee, Kee-Hang;Nam, Hyun;Won, Jeong-Seob;Hwang, Ji-Yoon;Jang, Hye Won;Lee, Sun-Ho;Joo, Kyeung Min
    • Journal of Korean Neurosurgical Society
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    • 제61권4호
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    • pp.434-440
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    • 2018
  • Objective : The purpose of this study was to find an optimal delivery route for clinical trials of intrathecal cell therapy for spinal cord injury in preclinical stage. Methods : We compared in vivo distribution of Cy5.5 fluorescent dye in the spinal cord region at various time points utilizing in vivo optical imaging techniques, which was injected into the lateral ventricle (LV) or cisterna magna (CM) of rats. Results : Although CM locates nearer to the spinal cord than the LV, significantly higher signal of Cy5.5 was detected in the thoracic and lumbar spinal cord region at all time points tested when Cy5.5 was injected into the LV. In the LV injection Cy5.5 signal in the thoracic and lumbar spinal cord was observed within 12 hours after injection, which was maintained until 72 hours after injection. In contrast, Cy5.5 signal was concentrated at the injection site in the CM injection at all time points. Conclusion : These data suggested that the LV might be suitable for preclinical injection route of therapeutics targeting the spinal cord to test their treatment efficacy and biosafety for spinal cord diseases in small animal models.

진공 다이캐스팅 공법의 사출조건에 따른 연료전지용 분리판 성형 해석 및 제조 공정 (Fabrication Process and Forming Analysis of Fuel Cell Bipolar Plate by Injection Condition of Vacuum Die Casting)

  • 진철규;장창현;김재성;최재원;강충길
    • 한국주조공학회지
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    • 제31권5호
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    • pp.274-283
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    • 2011
  • The vacuum die casting is a promising candidate of the stamping process for fabrication of fuel cell bipolar plate due to its advantages, such as precision casting, mass production and short production time. This study proposes vacuum die casting process to fabricate bipolar plates in fuel cell. Bipolar plates were fabricated under various injection conditions such as molten metal temperature and injection velocity. Also, according to injection velocity conditions, simulation results of MAGMA soft were compared to the experimental results. In case of melt temperature $650^{\circ}C$, misrun occurred. When the melt temperature was $730^{\circ}C$, mechanical properties were low due to dendrite microstructure. Injection velocity has to set at more than 2.0 m/s to fabricate the sound sample. When melt temperature, injection velocity (Fast shot), and vacuum pressure are $700^{\circ}C$, 2.5 m/s and 30 kPa respectively, sample had good formability and few casting defects. Simulation results are mostly in agreement with experimental results.