• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.6 s.360
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• pp.31-39
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• 2007

In this paper, a system for real-time or periodic measurement and analysis of RF parameters such as forward transmit power and pilot power in CDMA base station systems is proposed. Such RF characteristic parameter measurement can be prevented from system fault and used to achieve optimal service quality and maximum investment return through cell coverage expansion, subscriber capacity increase and so on. For forward power measurement, the local oscillator frequency for the detector is varied so that the transmit power for all channels can be measured. The channel power measurement can be used to analyze the variation in transmit power for changes in voice traffic. By comparing to forward $E_c/I_o$, the pilot channel power can be deducted, which can be used to determine uy degradation in transmit section modules such as the high dover amplifier. Since an accurate analysis of carefully measured data using the CDMA level detector must be made, the system is designed so that measurement errors due to changes in crest factor with modulation method can be overcome.

• The Journal of Advanced Prosthodontics
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• v.5 no.1
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• pp.44-50
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• 2013

PURPOSE. The aim of this study was to evaluate the effects of repeated porcelain firing process on the corrosion rates of the dental alloys. MATERIALS AND METHODS. Cr-Co, Cr-Ni and Pd-Ag alloys were used for this study. Each metal supported porcelain consisted of 30 specimens of 10 for 7, 9 and 11 firing each. Disc-shaped specimens 10 mm diameter and 3 mm thickness were formed by melting alloys with a propane-oxygen flame and casted with a centrifuge casting machine and then with the porcelain veneer fired onto the metal alloys. Corrosion tests were performed in quintuplicate for each alloy (after repeated porcelain firing) in Fusayama artificial saliva solution (pH = 5) in a low thermal-expansion borosilicate glass cell. Tamhane and Sheffe test was used to compare corrosion differences in the results after repeated firings and among 7, 9 and 11 firing for each alloy. The probability level for statistical significance was set at ${\alpha}$=0.05. RESULTS. The corrosion resistance was higher (30 mV), in case of 7 times firing (Commercial). On the other hand, it was lower in case of 11 times firing (5 mV) (P<.05). Conclusion. Repeated firings decreased corrosion resistance of Pd-Ag, Cr-Co and Cr-Ni alloys. The Pd-Ag alloy exhibited little corrosion in in vitro tests. The Cr-Ni alloy exhibited higher corrosion resistance than Cr-Co alloys in in vitro tests.

• Journal of Embryo Transfer
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• v.28 no.4
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• pp.361-371
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• 2013

The present study assessed the effect of FSH and LH on oocyte meiotic, cytoplasmic maturation and on the expression level and polyadenylation status of several maternal genes. Cumulus-oocyte complexes were cultured in the presence of FSH, LH, or the combination of FSH and LH. Significant cumulus expansion and nuclear maturation was observed upon exposure to FSH alone and to the combination of FSH and LH. The combination of FSH and LH during entire IVM increased the mRNA level of four maternal genes, C-mos, Cyclin B1, Gdf9 and Bmp15, at 28 h. Supplemented with FSH or LH significantly enhanced the polyadenylation of Gdf9 and Bmp15; and altered the expression level of Gdf9 and Bmp15. Following parthenogenesis, the exposure of oocytes to combination of FSH and LH during IVM significantly increased cleavage rate, blastocyst formation rate and total cell number, and decreased apoptosis. In addition, FSH and LH down-regulated the autophagy gene Atg6 and upregulated the apoptosis gene Bcl-xL at the mRNA level in blastocysts. These data suggest that the FSH and LH enhance meiotic and cytoplasmic maturation, possibly through the regulation of maternal gene expression and polyadenylation. Overall, we show here that FSH and LH inhibit apoptosis and autophagy and improve parthenogenetic embryo competence and development.

• Economic and Environmental Geology
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• v.49 no.1
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• pp.23-30
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• 2016

Powder samples of natural lawsonite (Ca-lawsonite, $CaAl_2Si_2O_7(OH)_2{\cdot}H_2O$) was studied structurally up to 8 GPa at room temperature using monochromatic synchrotron X-ray powder diffraction and a diamond anvil cell (DAC) with a methanol : ethanol : water (16 : 3 : 1 by volume) mixture solution as a penetrating pressure transmitting medium (PTM). Upon pressure increase, lawsonite does not show any apparent pressure induced expansion (PIE) or phase transition. Pressure-volume data were fitted to a second-order Birch-Murnaghan equation of state using a fixed pressure derivative of 4 leading to a bulk modulus ($B_0$) of 146(6) GPa. This compression is further characterized to be isotropic with calculated linear compressibilities of ${\beta}^a=0.0022GPa^{-1}$, ${\beta}^b=0.0024GPa^{-1}$, and ${\beta}^c=0.0020GPa^{-1}$.

• Journal of fish pathology
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• v.21 no.2
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• pp.81-91
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• 2008

Vibrio harveyi, one of the major causal agent of vibriosis, affects a diverse range of marine vertebrates and invertebrates over a wide geographical area. The aims of this study were to investigate the characteristics of extracellular products (ECPs) from an isolate of the pathogenic non‐luminous V. harveyi and the luminous V. harveyi. And ECPs of V. harveyi were examined the pathogenicity to the black rockfish, Sebastes schlegeli, and histopathological traits of internal organs injected by ECPs. Four strains of V. harveyi cultures produced ECPs showing various enzymatic activites (caseinase, gelatinase, phospholipase, lipase, haemolysin). The ECPs showed strong cytotoxicity on macrophages of black rockfish, Sebastes schlegeli and olive flounder, Paralichthys olivaceus. Especially, the virulence of ECPs from the isolate of V. harveyi FR 2 was higher in the intraperitoneally injected black rockfish. Also, the ECPs of V. harveyi FR 2 caused the expansion of sinusoids in the liver, the activation of ellipsoid in the spleen and the sloughing of the epidermal cell in the intestine. It was suggested that the ECPs from V. harveyi play an important role in the pathogenicity process of the V. harveyi.

• Korean Journal of Food Science and Technology
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• v.34 no.4
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• pp.597-603
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• 2002

The analysis of traditional process for a Korean puffed rice snack (Yukwa) is needed to develop an advanced process for Yukwa-making. Steeping and punching (Koarichigi) processes, consume time and labor in Yukwa-making, were analyzed on this study. Steeping of waxy rice at $15^{\circ}C$ for 3 days was required to equilibrate moisture absorption in waxy rice kernel. However, steeping for more than 6 days was required soft texture and small air cell distribution of Yukwa. Protein content at pericarp on endosperm of waxy rice kernel was decreased and starch granule was damaged during steeping. RVA paste viscosity was the highest at 6 day steeping after than decreased. Expansion ratio of Yukwa was increased with the increase in steeping time. Air bubbles in dough after punching were uniformly distributed and kneading energy input was decreased with the increase in steeping time. Soft texture, unique texture of Yukwa could be controlled by controlling steeping time and kneading energy input during punching process.

• Journal of the Korean Institute of Gas
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• v.25 no.2
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• pp.28-33
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• 2021

With the recent growing interest in eco-friendly cars, as interest in eco-friendly cars increases, interest and purchase of hydrogen fuel cell vehicles that do not emit pollutants are increasing. Recently, the government is supporting the expansion of hydrogen charging station and localization of core parts according to the government's hydrogen energy dissemination policy. In this study, the flow characteristics of the hydrogen flow control valve were investigated. As the differential pressure increases, the mass flow rate and flow coefficient tend to be different from the volume flow rate. And it was confirmed that it affects the hydrogen temperature due to the nozzle effect in the bottleneck section, and the change in density affects the mass flow rate.

• Journal of the Korean Institute of Gas
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• v.25 no.5
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• pp.19-29
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• 2021

Due to the climate changing, the world's countries are tightening regulations on CO2 and air pollutants emission to solve them. In addition, eco friendly vehicles is increasing to replace automobiles in internal combustion engine. Recently, the government is supporting the expansion of hydrogen refueling infrastructure and localization of core equipment in refueling facilities according to the hydrogen economy road map. In this study, design of the Excess flow limiting device in FCEV cylinder valve using by finite element analysis and performed performance tests on prototype. Major test results as hydrostatic strength, continued operation, operation, pressure impulse, leakage showed that the excess flow limiting device meets the performance requirements according to ISO 12619-2 and ISO 12619-11.

• BMB Reports
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• v.56 no.3
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• pp.178-183
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• 2023

Huntington's disease (HD) is a neurodegenerative disorder, of which pathogenesis is caused by a polyglutamine expansion in the amino-terminus of huntingtin gene that resulted in the aggregation of mutant HTT proteins. HD is characterized by progressive motor dysfunction, cognitive impairment and neuropsychiatric disturbances. Histone deacetylase 6 (HDAC6), a microtubule-associated deacetylase, has been shown to induce transport- and release-defect phenotypes in HD models, whilst treatment with HDAC6 inhibitors ameliorates the phenotypic effects of HD by increasing the levels of α-tubulin acetylation, as well as decreasing the accumulation of mutant huntingtin (mHTT) aggregates, suggesting HDAC6 inhibitor as a HD therapeutics. In this study, we employed in vitro neural stem cell (NSC) model and in vivo YAC128 transgenic (TG) mouse model of HD to test the effect of a novel HDAC6 selective inhibitor, CKD-504, developed by Chong Kun Dang (CKD Pharmaceutical Corp., Korea). We found that treatment of CKD-504 increased tubulin acetylation, microtubule stabilization, axonal transport, and the decrease of mutant huntingtin protein in vitro. From in vivo study, we observed CKD-504 improved the pathology of Huntington's disease: alleviated behavioral deficits, increased axonal transport and number of neurons, restored synaptic function in corticostriatal (CS) circuit, reduced mHTT accumulation, inflammation and tau hyperphosphorylation in YAC128 TG mouse model. These novel results highlight CKD-504 as a potential therapeutic strategy in HD.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.33-43
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• 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made significant impacts on global public health, including the development of several skin diseases that have arisen primarily as a result of the pandemic. Owing to the widespread expansion of coronavirus disease 19 (COVID-19), the development of effective treatments for these skin diseases is drawing attention as an important social issue. For many centuries, ginseng and its major active ingredients, ginsenosides and saponins, have been widely regarded as herbal medicines. Further, the anti-viral action of ginseng suggests its potential effectiveness as a therapeutic agent against COVID-19. Thus, the aim of this review was to examine the association of skin lesions with COVID-19 and the effect of ginseng as a therapeutic agent to treat skin diseases induced by COVID-19 infection. We classified COVID-19-related skin disorders into three categories: caused by inflammatory, immune, and complex (both inflammatory and immune) responses and evaluated the evidence for ginseng as a treatment for each category. This review offers comprehensive evidence on the improvement of skin disorders induced by SARS-CoV-2 infection using ginseng and its active constituents.