• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.82-85
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• 2007

The Chinese medicinal plant Artemisia annua is the source of the antimalarial compound artemisinin. By the way, Artemisin annula was known have endoperoxide ring structure is included and has anti-malarial effect. Malaria and Toxoplasma gondii (T. gondii) is belong to Apicomplexa genera. So, confirmed whether we go compound 1,5-bis(4-methoxyphenyl)-6,7-dioxa-bicyclo[3.2.2]nonane that have endoperoxide ring structure and there is anti-toxoplasmosis effect. The efficacy of 1,5-bis(4-methoxyphenyl)-6,7-dioxa-bicyclo[3.2.2] nonane alone was examined in vitro and in a murine model of acute toxoplasmosis. In vitro studies were peformed with HeLa cell cultures, with quantification of Toxoplasma growth by a cell proliferation assay. Selectivity of 1,5-bis(4-methoxyphenyl)-6,7-dioxa-bicyclo[3.2.2]nonane was 4.9 in vitro cell proliferation assay, this is higher than sulfadiazine (selectivity was 1.63). For in vivo studies, mice were acutely infected intraperitoneally with 10$^5$ tachyzoites of the virulent RH strain and then treated perorally for 4 days from 6 hours postinfection. Efficacy was assessed by sequential determination of parasite burdens in peritoneal cavity. in vitro, 1,5-bis(4-methoxyphenyl)-6,7-dioxa-bicyclo[3.2.2]nonane inhibited Toxoplasma growth at a concentration of 150mg/kg of body weight per day, the inhibition ratio was estimated to be 85.72%.

• Journal of Korean society of Dental Hygiene
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• v.2 no.1
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• pp.43-61
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• 2002

The purpose of this study was focus on development of educational objectives by using oral health education in the elementary school from now on. Based on the results of analysis compared with a model of educational objectives and contents by reflecting the programs for analysis were the oral health education programs of the Ministry of health and social Affairs in Korea, and the programs of two states in u.s. in order to construct goals and contents of oral health education in school. The results in this study can be arranged as follows: First, an analysis on the educational objectives of dental health education program resulted that, from a viewpoint of Bloom's taxonomy of educational objectives, in case of domestic, most learning objectives expressed in the handbook of Ministry of Health and social Welfare were given too much emphasis to the cognitive domain of 37 an items in all. Affective domain were appeared the lack of balance of the development domain. Second, the result of analysis for the programs of two states of America, the cognitive domain were the most abundant of 48 an items in all, and were not significantly different to those of Korea in the form of objectives domain or statement. However a big different was shown that they organized the same objectives domain as a pattern of repeating and deepening at every grade. Third, in this study, 10 educational objectives of dental health education were established, based on the result of analyzing those existing educational programs as central figure. Those are oral cavity, brushing, nutrition of teeth, fluoride, flossing, teeth injury, dental decay, periodontal disease, malocclusion, routine dental visits. And general objectives and specific objectives of each learning area were stated and arranged grade by grade.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.44 no.12
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• pp.1062-1070
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• 2016

The heat transfer and flow characteristics of gas turbine blade tip were investigated in this paper by using the conjugate heat transfer analysis. The rotor inlet boundary condition profile which was taken from the first stage nozzle outlet was used to analyse. The profile contained the velocity and temperature information. This study presents the influence of tip clearance about aerodynamic loss, heat transfer coefficient and film cooling effectiveness with the squealer tip designed blade model which tip clearance variation range from 1% to 2.5% of span. Results showed that the aerodynamic loss and the heat transfer coefficient were increased when the tip clearance was increased. Especially when the tip clearance was 2% of the span, the average heat transfer coefficient on the tip region was increased obviously. The film cooling effectiveness of tip region was increasing with decreasing of the tip clearance. There was high film cooling effectiveness at cavity and near tip hole region.

• Journal of Nutrition and Health
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• v.7 no.4
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• pp.6-11
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• 1974

1. The status of nutrition hasn't been found a great difference between the model village and the compared one, so there should be a great need of the improvement of the traditional food life which is chiefty consisted of some cereal grains and vegetables, in a Larger sense, the mixing diet would diminish the burden of stomach and help us to get high nutrition with a bit of quantify. 2. The health of the oral cavity has a close relation with that of whole body. In order to keep a good dental health, there fore, we should study and try to get more calcium in another food group except in the vegetarian diet. The pregnant women must especially have much recognition to the necessity for getting a lot of calcium. 3. It is desirable to clean our teeth three times every day after having meals for every three minutes. The habit which is called 'three three three campaign' should clearly be kept for all of us.

• The korean journal of orthodontics
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• v.47 no.5
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• pp.313-322
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• 2017

Objective: Miniscrew-assisted rapid palatal expansion (MARPE) is a means for expanding the basal bone without surgical intervention in young adults. Here, we assessed the differences in dental, alveolar, and skeletal measurements taken before (T0), immediately after (T1), and 1 year after (T2) MARPE. Methods: Twenty-four patients (mean age, 21.6 years) who had undergone MARPE and cone-beam computed tomography at T0, T1, and T2 were included. Changes in the following parameters were compared using paired t-tests: intercusp, interapex, alveolar, nasal floor, and nasal cavity widths; inclination of the first molar (M1) and its alveolus; and thickness and height of the alveolar bone. A linear mixed-effects model was used to determine variables that affected periodontal changes in the M1. Results: MARPE produced significant increases in most measurements during T0-T2, despite relapse of some measurements during T1-T2. The alveolar thickness decreased on the buccal side, but increased on the palatal side. The alveolar crest level at the first premolar moved apically. Changes in the thickness and height of the alveolar bone were affected by the corresponding initial values. Conclusions: MARPE can be used as an effective tool for correcting maxillomandibular transverse discrepancy, showing stable outcomes 1 year after expansion.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.14 no.6
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• pp.638-647
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• 2003

Triangular patches have been studied, both theoretically and experimentally. We feund that provided radiation characteristics similar to those of rectangular patches, but with smaller size. In this paper, we designed an equilateral triangular microstrip patch antenna using cavity model analysis. Then, in order to improve narrow bandwidth, we add capacitive gap and air gap. Capacitive gap is located with square shape beside feeding point on the patch, and air gap is inserted between substrate dielectric and ground plane to adjust probe inductance. The analysis of characteristics and effects of each component was performed by commercial simulation tool, Ensemble 5.0. Throughout the simulation and experiment, we found the possibility of bandwidth enhancement in triangular microstrip antenna.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.8
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• pp.21-29
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• 2002

In the present study, a passive control method, using a porous wall and cavity system, is applied to the shock wave/boundary layer interactions in transonic moist air flow. The two-dimensional, unsteady, compressible, Navier-Stokes equations, which are fully coupled with a droplet growth equation, are solved by the third-order MUSCL type TVD finite difference scheme. Baldwin-Lomax model is employed to close the governing equations. In order to investigate the effectiveness of the present control method, the total pressure loss of the flow and the time-dependent behaviour of shock motions are analyzed in detail. The computed results show that the present passive control method considerably reduces the total pressure losses due to the shock wave/boundary layer interaction in transonic moist air flow and suppresses the unsteady shock wave motions over the airfoil as well. It is also found that the location of the porous ventilation significantly affects the control effectiveness.

• Proceedings of KOSOMES biannual meeting
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• 2005.11a
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• pp.159-163
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• 2005

This experimental study was performed to investigate internal flow and unsteady flow characteristics using a model for actual shape of a plate heat exchanger and visualization of flow through the particle image velocimetry. Seven Reynolds numbers were selected by calculation with the height of grooved channel and sectional mean velocity of inlet flow in the experiment, and instantaneous velocity distributions and flow characteristics were experimently investigated. The triangular grooved channel had a compound flow consisting of the flow in lower channel and the groove flow receiving shear stress by the channel flow in the experiment. The sheared mixing layer, in the boundary between the triangular groove and the channel, affected main flow to raise turbulent in the channel.

• Journal of the Optical Society of Korea
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• v.19 no.1
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• pp.69-73
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• 2015

The mesothelium is an essential lining for maintaining the normal homeostasis of the closed body cavity and a central component of pathophysiologic processes. The mesothelium has been known as the end target for asbestos which induces asbestos-related lung diseases. Malignant mesothelioma (MM) is a rare and fatal neoplasm predominantly due to asbestos exposure. Adaptation of an advanced and reliable technology is necessary for early detection of MM because it is difficult to diagnose this disease in its early stages. Optical coherence tomography (OCT) provides cross-sectional images of micro-tissue structures with a resolution of $2-10{\mu}m$ that can image the mesothelium with a thickness of ${\sim}100{\mu}m$ and, therefore, enable investigation of early development of MM. The mesothelium is typically located at the pleura and tunica vaginalis of the scrotum. In this study, we developed animal window models in the above two anatomical sites to visualize mesothelial layers within the mesothelium. OCT images at the two locations were also acquired.

• Imaging Science in Dentistry
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• v.42 no.1
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• pp.19-24
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• 2012

Purpose : Field of view and voxel resolution of cone beam computed tomography (CBCT) might affect the diagnostic capability. This study was performed to compare between the standard and HiRes zoom modes in the diagnosis of external root resorption (ERR) using CBCT. Materials and Methods : Sixty three small cavities (0.25 mm depth and 0.5 mm diameter) were simulated on the buccal, lingual, and proximal surfaces at three different levels of 16 roots of teeth. After covering the root with nail varnish, the roots were inserted in the sockets and the model was placed in a water-containing lacuna. CBCT scans were taken in both standard and HiRes zoom modes using NewTom VG (QR srl Company, Verona, Italy). Then, an observer assessed the images to determine the presence or absence of the cavities. This process was repeated by increasing the size and depth of cavities to 0.5 mm depth and 1 mm diameter. Data were analyzed by McNemar test. The sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratio in evaluation of the simulated cavities were calculated. Results : There was a significant difference between the two imaging modes in diagnosing the shallow cavities (p=0.02).The sensitivity of the standard zoom in detecting the shallow cavities was lower than that of the HiRes zoom. The likelihood ratio of the HiRes zoom was higher in the diagnosis of both cavity types. Conclusion : This study suggested that a smaller voxel size in the HiRes zoom mode of CBCT is preferred for diagnosis of ERR.