• Bulletin of the Korean Chemical Society
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• 제28권4호
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• pp.538-542
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• 2007

Polymeric electrodes for lead ion based on N,N'-bis-thiophen-2-ylmethylene-pyridine-2,6-diamine as an ion carrier were prepared. The membrane electrode (m-3) containing o-NPOE as a plasticizer and 50 mol% additive of ionophore gives an excellent Nernstian response (29.59 mV/decade) and the limit of detection of ?log a (M) = 5.74 to Pb2+ in Pb(NO3)2 solution at room temperature. The prepared electrode provided good sensitivity and outstanding selectivity and response for Pb2+ over a wide variety of other metal ions in pH 7.0 buffer solutions. The good sensitivity and selectivity towards lead ion are attributed to the strong complexation of lead ion to N,N'-bis-thiophen-2-ylmethylene-pyridine-2,6-diamine which has geometrically the proper cavity to coordinate to the ligand.

• 대한소아치과학회지
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• 제23권4호
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• pp.775-787
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• 1996

The purpose of this study was to investigate the postnatal development of pulpal innervation with the tooth development and eruption process in developing rat mandibular molars (postnatal 1, 5, 10, 15, 20, 25, 35day-old and adult rats). Immunohistochemical method was carried out for the detection of nerve fibers, using the antibody against calcitonin gene-related peptide(CGRP). The results were as follows: The feature of CGRP-IR nerve fibers were shown in a bead-like appearance. The time of nerve entering into the dental papilla of tooth follicle began at the occured advanced dentinogenesis. The development of Raschkow plexus began at the formative stage of the roots and was accelerated at the stage of the crown emerged into the oral cavity. The number of nerve fibers entering the odontoblastic layer increased with the tooth eruption and mastication. The development of innervation was shown to be related with the stage of the development of individual teeth rather than the chronological age of the rat.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2002년도 봄 학술발표회 논문집
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• pp.63-70
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• 2002

In tunnel construction, the information on the rock quality and the location of fault or fracture are crucial for economical design of support pattern and for safe construction of the tunnel. The grade of rock is commonly estimated through the observation with the naked eye of recovered cores in drilling or from physical parameters obtained by their laboratory test. Since drilling cost is quite expensive and terrains of planned sites for tunnel construction are rough in many cases, however, only limited information could be provided by core drilling Electrical resistivity and EM surveys may be a clue to get over this difficulty. Thus we have investigated electrical resistivity and EM field data providing regional Information of the rock Quality and delineating fault and fracture over a rough terrain. In this paper, we present some case histories using electrical resistivity and EM survey for the site investigation of tunnel construction. Through electrical resistivity and EM survey, the range and depth of coal seam was clearly estimated, cavities were detected in limestone area, and weak zones such as joint, fault and fracture have been delineated.

• Journal of Multimedia Information System
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• 제6권2호
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• pp.81-86
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• 2019

Deep learning is emerging as one of the best tool in processing data related to medical imaging. In our research work, we have proposed a deep learning based framework CNN (Convolutional Neural Network) for the classification of dysplastic tissue images. The CNN has classified the given images into 4 different classes namely normal tissue, mild dysplastic tissue, moderate dysplastic tissue and severe dysplastic tissue. The dataset under taken for the study consists of 672 tissue images of epithelial squamous layer of oral cavity captured out of the biopsy samples of 52 patients. After applying the data pre-processing and augmentation on the given dataset, 2688 images were created. Further, these 2688 images were classified into 4 categories with the help of expert Oral Pathologist. The classified data was supplied to the convolutional neural network for training and testing of the proposed framework. It has been observed that training data shows 91.65% accuracy whereas the testing data achieves 89.3% accuracy. The results produced by our proposed framework are also tested and validated by comparing the manual results produced by the medical experts working in this area.

• 한국가시화정보학회지
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• 제20권3호
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• pp.128-135
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• 2022

Cavitation occurs inevitably in marine propellers rotating at high speed in the water, which is a major cause of underwater radiated noise. Cavitation-induced noise from propellers rotating at a specific frequency not only reduces the sonar detection capability, but also exposes the ship's location, and it causes very fatal consequences for the survivability of the navy vessels. Therefore cavity inception speed (CIS) is one of the important factors determining the special performance of the ship. In this study, we present a method using computer vision that can detect and quantitatively estimate tip vortex cavitation on a propeller rotating at high speed. Based on the model test results performed in a large cavitation tunnel, the effectiveness of this method was verified.

• 센서학회지
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• 제33권3호
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• pp.158-164
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• 2024

We developed a self-operated paper pump that can maintain a nearly constant flow rate of an aqueous solution along a paper strip channel in paper-based analytical devices (PADs). The quasi-stationary flow rate was controlled by increasing the crosssectional channel area (capillary force) using a fan-shaped absorption pad coupled with a paper strip channel. The flow rate is regulated by varying the fan angle of the circular absorbing pad. Furthermore, the flow rate can be increased by furnishing a hollow cavity at the center of a conventional paper strip channel. The rate was regulated by varying the length of the hollow paper channel in the flow rate range of 5.1-26.4 mm/min. As a preliminary work, a paper-pump-coupled PAD was fabricated, and its CV detection capability was evaluated for the redox reaction of Fe(CN)₆^+4/+3. The combination of a paper pump with a PAD resulted in an ideal CV curve with a higher limiting current and faster response time. These results are interpreted well by the Levich equation, which suggests that the paper pump is a very useful component in paper-based sensors.

• Imaging Science in Dentistry
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• 제54권2호
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• pp.211-220
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• 2024

Non-secretory multiple myeloma (NSMM) is a rare cancer of plasma cells characterized by the absence of detectable monoclonal M protein in the blood or urine. A 57-year-old woman presented with mandibular pain but without intraoral swelling. Imaging studies revealed multiple osteolytic lesions in her mandible and pronounced root resorption of the left mandibular second molar. Biopsy results showed atypical plasmacytoid cells positive for anti-kappa, CD138, MUM1, and CD79a antibodies, but negative for anti-lambda and CD20. These results were indicative of a malignant plasma cell neoplasm. No abnormalities were revealed by free light chain assay or by serum or urine protein electrophoresis, leading to a diagnosis of NSMM. The patient began chemotherapy in conjunction with bisphosphonate therapy and achieved remission following treatment. This case underscores the critical role of dentists in the early detection and prevention of NSMM complications, as the disease can initially present in the oral cavity.

• 지구물리와물리탐사
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• 제9권4호
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• pp.271-278
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• 2006

국내 지반침하의 주요 원인 중의 하나인 석회암 공동에 대한 조사는 단순한 지반침하 원인의 규명 이외에 지반 침하 지역 또는 예상지역의 보강 설계 및 사후 관리에 이르기까지 폭넓은 지반 정보를 제공하는 역할을 수행한다는 측면에서 매우 중요하다고 할 수 있다. 지반침하지역 공동탐지에 유용하게 사용되는 물리탐사기법으로 한 종류의 지반 물성을 이용하는 단위 물리탐사기술보다는 여러 가지 물성의 지하를 조명하는 복합 물리탐사기술에 대한 연구가 필요하다. 본 연구에서는 지반침하조사 시 지하공동 탐지를 위한 복합 물리탐사 시스템 구축의 일환으로 전라남도 무안군 무안읍 용월리에 과거 석회암 공동에 의한 지반침하 경력이 있는 지역을 현장 실험장으로 이용하여 다양한 종류의 물리탐사를 실시하였다. 그 중 전기비저항탐사, 전자탐사 그리고 고정밀 중력탐사 결과로부터 지하 공동의 위치 및 분포를 추정 해석하고, 시추조사 결과와 비교함으로서 단위 물리탐사 기술의 공동탐지 적용성에 대하여 고찰하였다. 시추조사결과, 실험장 지역 기반암내 공동은 대부분 지하수 또는 물로 포화된 점토로 채워져 있어 주위 기반암에 비하여 매우 낮은 전기비저항 및 밀도를 가지며, 넓은 지역에 걸쳐 망구조로 분포하고 있는 것으로 해석된다. 실험장에 적용한 전기비저항, 전자 및 고정밀 중력 탐사 결과, 저비저항대와 음의 중력 이상대 분포 지역이 시추 조사에서 확인된 지하 공동의 분포 위치와 상당 부분 일치함을 보여 이들 각 탐사법들이 지하 공동 분포 파악에 효과적임이 입증되었다. 또한 개별 탐사 기법 해석과 아울러 각종 탐사결과를 종합함으로써 보다 정확한 지하공동의 분포 해석이 가능하였으며, 특히 국내에서의 사용이 미비하였던 고정밀 중력탐사기법이 지하공동 탐지에 매우 유용함을 확인하였다.

• 대한두경부종양학회지
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• 제17권2호
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• pp.162-168
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• 2001

Background: Inverted papilloma(IP) of the nasal cavity and paranasal sinuses is a benign neoplastic condition that can be associated with squamous cell carcinoma (SCC). Several studies have indicated an etiologic role for viruses in the development of inverted papilloma. And it is necessary to find out the significance of a biologic markers such as p53, c-erbB-2 to predict the malignant potential. The purposes of this study are to detect HPV in inverted papilloma of the nasal cavity and paranasal sinus, to examine role of HPV as an etiological agent, to examine the relationship between HPV subtype and malignant transformation of inverted papilloma, and to investigate the relation between expression rate of p53, c-erbB-2 and HPV in recurrent or malignant transformation cases. Material and Methods: Thirty two cases of inverted papilloma(IP) in the nasal cavity and paranasal sinuses were reviewed and classified into 3 groups; simple IP, IP with dysplasia group, IP with squamous cell carcinoma group. Paraffin embedded achival tissue was used in this study. The HPV was detected by in situ hybridzation (ISH) using HPV type 6/11, 16/18, 31/33/35 DNA probes. Expression of p53 and c-erbB-2 was examined by immunohistochemical staining. Results: 1) The HPV was detected in 6(19%) out of 32 cases. 2) The HPV 6/11 was dectected in 4 out of 21 cases of simple IP, HPV 16/18 in 1, HPV 31/33/35 in lout of 8 cases of IP with dysplasia respectively. 3) The positive expression of p53 was 13 cases out of 32 cases; 2 out of 21 cases of simple IP, all of 8 cases of IP with dysplasia and 3 cases of IP with squamous cell carcinoma 4) The positive expression of c-erbB-2 was in 24 out of 32 cases; 16 out of 21 cases of simple IP, 6 out of 8 cases of IP with dysplasia, 2 out of 3 cases of IP with squamous cell ca. 5) The recurrence of IP occurred in lout of 6 cases of positive for HPV, in 4 out of 26 cases negative for HPV. 6) The recurrence of IP occurred only in positive cases for p53. 7) The recurrence of IP occurred in 4(17%) out of 24 cases positive for c-erbB-2, in 1(13%) out of 8 cases negative for c-erbB-2. Conclusion: The p53 expression was associated with Inverted papillomas exhibiting evidence of malignant transformation. Also, there was a correlation between the p53 expression and recurrence.

• 대한소아치과학회지
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• 제37권4호
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• pp.532-536
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• 2010

Hidden caries는 임상 검사상 교합면이 매우 건전하거나 소량의 탈회만이 관찰되지만 방사선 사진 상에서 상당 수준 진행된 상아질 우식이 발견되는 경우를 일컬으며 Covert caries, Occult caries, Fluoride syndrome 등이 동의어로 사용되고 있다. 발생 원인으로는 불소의 영향, 세균의 종류 및 세균 영양분 공급 경로의 차이, 열구 기저면으로부터 시작된 우식증, 맹출 전우식증 등의 주장들이 제기되고 있지만 현재 정확한 원인은 밝혀지고 있지 않다. 본 증례는 임상 및 방사선 사진 검사에서 Hidden caries를 발견한 두 환아들의 치험례로 두 증례 모두에서 깊은 상아질 우식을 보여 각각 치근단 형성술과 간접치수복조술을 시행하였다. 교합면이 비교적 건전해 보이는 특징 뿐만 아니라 Hidden caries의 우식 상아질은 임상적으로 관찰 가능한 우식에서 채취한 우식 상아질에 비해 밝은 색을 띄는 특징이 있어 시진으로 관찰하기 더욱 어려운 것으로 생각된다. 따라서 본 증례와 같이 진행된 우식병소로 인해 임상증상이 발현된 후에야 이를 발견하게 되는 경우가 많으므로 정기적인 방사선 검사와 함께 Diagnodent.. 등과 같은 최신의 우식 진단도구들의 사용으로 우식병소의 조기진단을 위해 노력해야 할 것으로 생각된다.