• 제목/요약/키워드: Causes of Decline

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인지기능 감퇴가 있는 노인의 이중 과제 보행과 인지기능과의 상관성에 대한 체계적 문헌 고찰 (The Correlation between Gait and Cognitive Function in Dual-task Walking of the Elderly with Cognitive Impairment: A Systematic Literature Review)

  • 신재연;김예진;김지수;민수빈;박재니;배재한;서희은;신희선;유영은;임주영;장지수;조영우;이한숙
    • 대한물리의학회지
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    • 제17권1호
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    • pp.93-108
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    • 2022
  • PURPOSE: This review sought to confirm the correlation between dual-task gait and cognitive function in cognitively impaired and healthy older adults. METHOD: We used four databases (DBs), Pubmed, Cochrane library, Kmbase, and Koreamed. Searches were carried out according to the PICOS method, P (participants) were the elderly (above 65 years) with cognitive decline, I (intervention) was walking with dual tasks, C (control group) comprised the elderly without cognitive decline, O (outcome) was the correlation between gait and cognitive function and S (study) was the cross-sectional study. For the methodological quality assessment of each study, we used the Quality Assessment Tool for Observation Cohort and Cross-Sectional Studies provided by the National Institutes of Health (NIH). RESULTS: A total of 10 articles were included in this systematic review. For the components of gait, we used pace, rhythm, and variability and we observed that mild cognitive impairment mostly causes low gait performance while performing dual tasks. Among the 10 articles, 9 articles studied pace, of which 7 showed significant results. However, 2 were not significant. Also, 1 article that studied rhythm and 3 articles that studied variability showed significant results. The methodological quality of the 10 studies was fair. CONCLUSION: Gait pace was found to have a high correlation between memory, which is a cognitive ability, and overall cognitive function. It was observed that older adults with mild cognitive impairment have reduced gait pace in single-task walking, and further decrease in dual-task gait pace shows the correlation between memory and gait pace during walking.

갱년기 여성을 위한 앱 기반의 인지기능훈련 프로그램 개발 (Development of mobile-application based cognitive training for Menopausal Women with Cognitive Complaints)

  • 김지현
    • 한국산학기술학회논문지
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    • 제21권5호
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    • pp.150-166
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    • 2020
  • 본 연구는 인지예비능 이론에 입각하여 인지기능감퇴를 호소하는 갱년기 여성들을 위해 인지기능훈련 프로그램을 개발하고자 하였다. Jung의 웹기반 교수-학습 체제 설계의 절차적 모형에 근거하여 분석, 설계 및 개발 단계를 거쳐 개발하였다. 인지기능훈련 프로그램은 8주간의 프로그램으로 모바일 애플리케이션을 활용한 인지훈련과 동영상 교육이며 총 24회기로 매 회기는 20~30분이 소요되며 3회/주 하도록 구성되었다. 인지기능훈련은 갱년기 여성들에 있어서 가장 취약한 인지영역으로 확인된 기억력, 주의집중력, 언어기능과 통합적 집행기능을 위한 시나리오기반 문제해결 등으로 내용을 구성하였다. 각 주차별 교육내용은 갱년기의 정의, 원인 및 증상, 갱년기와 뇌기능 등 총 8가지 주제로 개발되었다. 프로그램 시범운영을 위해 인지기능감퇴를 호소하는 10명의 갱년기 여성을 대상으로 인지기능훈련 프로그램을 적용하여 훈련 전과 훈련 8주후 인지기능의 효과를 측정한 결과 전반적 인지기능이 증가되었고 통계적으로 유의하였다(t=-3.04, p=.014). 모바일 앱 기반 인지기능훈련 프로그램은 기억력 향상뿐만 아니라 잠재적 치매 유병율을 감소시키는 효과도 기대할 수 있을 것이라 기대된다.

마을의 비보연못 특성 및 관리 - 강진 달마지 마을을 사례로 - (Characteristics and Management of Complementary Pond of Village - in Case of Dalmaji Village in Gangjin-gun -)

  • 박재철;한상엽;김도균
    • 농촌계획
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    • 제21권4호
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    • pp.157-165
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    • 2015
  • The purpose of this study is on identifying charactreistics and management direction of complementary pond of Dalmaji village in Gangjin. Accordingly, this village was indicated as Experience and Resort village by Korean government. This study describes the construction background and characteristics and identifies species diversity and characteristics through field survey. For this, literature and field survey was performed. In field survey, vegetational survey was performed in Aug. of 2015. D(Dominant degree) and S(Sociability degree) was measured by Brown-Blanquet's method. The answer was searched from Myungsanron(明山論), a textbook of Fengsui(風水) in Joseon dynasty. Of these causes, it was considered that the representative one is a protection of fire and infectious disease because the Wolgak mountain is a fire mountain(火山) as a stone mountain in Fengsui. The results demonstrate decline of aquatic ecosystem because of neglect management. The total number of species was 24. Of the species, Zelkova serrata is a natural vegetation of this complementary forest. This is nominated as Lagerstroemia indica and Camellia japonica community. Species composition demonstrate the characteristics of Korean southern region as mixed forest of evergreen trees and deciduous ones which are indigenous plants. It was considered Juniperus chinensis KaizukaVariega in central round island was planted in Japanese colonial period and it have to be removed. It was considered that name of moon pond and moon island etc. projects the mind of village ancestors which are going to reach an ideal condition of moon. And management of quantity and depth of pond water was critical for restoration of disappearing lotus from related literature. Periodic management was needed for ecological structure and function improvement because of ecological disturbance by the invasive plants like Humulus japonicus.

Academic Procrastination As A Challenge For Students' Mental Health In The Context Of Distance Learning And The Virtual World During The Covid-19 Pandemic

  • Stoliarchuk, Olesia;Khrypko, Svitlana;Olga, Dobrodum;Ishchuk, Olena;Kokhanova, Olena;Sorokina, Olena;Salata, Karina
    • International Journal of Computer Science & Network Security
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    • 제22권3호
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    • pp.276-284
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    • 2022
  • The research aims to study the dynamics of academic procrastination and its impact on the mental health of students during the transition to distance learning during the COVID-19 pandemic. At the beginning of the COVID-19 pandemic, it was identified a declining tendency of overall rates of academic procrastination and at the same time increase in the number of carriers of mid and high levels of academic procrastination. The decline in the general rates of academic procrastination at the beginning of 2021 testifies to the adaptation processes experienced by students to the conditions of distance learning. It was documented that students' academic procrastination is accompanied by a steady negative emotional tension. During the transition to distance learning, the intensity of students' learning activity has increased, which altogether causes stress as one of the main reasons for the academic procrastination among future psychologists. The study identified a risk of academic procrastination manifestation among students for their mental health, which provides a basis for developing and testing a program to prevent the phenomenon of academic procrastination among degree-seeking students.

Ingestion of Gouda Cheese Ameliorates the Chronic Unpredictable Mild Stress in Mice

  • Yun, Bohyun;Yoo, Ja Yeon;Park, Mi Ri;Ryu, Sangdon;Lee, Woong Ji;Choi, Hye Jin;Kang, Min Kyoung;Kim, Younghoon;Oh, Sangnam
    • 한국축산식품학회지
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    • 제40권1호
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    • pp.145-153
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    • 2020
  • Depression is a kind of mood disorder characterized by decline in motivation, interest, attention, mental activity, and appetite. Although depression is caused by a variety of causes, including genetic, endocrine and environmental stress, mild depression has been reported to improve with diet. Therefore, various type of food sources including functional and nutritional supplement are required to treat the depressive patients. Cheese contains bioactive peptides that have beneficial effects on host health. In particular, Jersey milk has been reported to contain higher solids than does Holstein milk. This study investigated the effects of Gouda cheese from Jersey and Holstein milk on chronic, unpredictable, mildly stressed (CUMS) mice. Here, spontaneous alterations in cheese-fed stressed mice were noted to be effectively recovered with statistical significance regardless cow species. Interestingly, for the analysis of fecal microbiota, Bacteroidetes were noted to increase with a reduction in Firmicutes at the phylum level with Jersey cheese. Taken together, we suggest that cheese intake provided a beneficial effect on stressed mice in recovering recognition ability. In particular, changes in internal microbiota were observed, suggesting that the bioactive ingredients in cheese act as improvement agents with respect to mood and brain function.

RADIATION DAMAGE IN THE HUMAN BODY ACUTE RADIATION SYNDROME AND MULTIPLE ORGAN FAILURE

  • AKASHI, MAKOTO;TAMURA, TAIJI;TOMINAGA, TAKAKO;ABE, KENICHI;HACHIYA, MISAO;NAKAYAMA, FUMIAKI
    • Nuclear Engineering and Technology
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    • 제38권3호
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    • pp.231-238
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    • 2006
  • Whole-body exposure to high-dose radiation causes injury involving multiple organs that depends on their sensitivity to radiation. This acute radiation syndrome (ARS) is caused by a brief exposure of a major part of the body to radiation at a relatively high dose rate. ARS is characterized by an initial prodromal stage, a latent symptom-free period, a critical or manifestation phase that usually takes one of four forms (three forms): hematologic, gastrointestinal, or cardiovascular and neurological (neurovascular), depending upon the exposure dose, and a recovery phase or death. One of the most important factors in treating victims exposed to radiation is the estimation of the exposure dose. When high-dose exposure is considered, initial dose estimation must be performed in order to make strategy decisions for treatment as soon as possible. Dose estimation can be based on onset and severity of prodromal symptoms, decline in absolute lymphocyte count post exposure, and chromosomal analysis of peripheral blood lymphocytes. Moreover, dose assessment on the basis of calculation from reconstruction of the radiation event may be required. Experience of a criticality accident occurring in 1999 at Tokai-mura, Japan, showed that ARS led to multiple organ failure (MOF). This article will review ARS and discuss the possible mechanisms of MOF developing from ARS.

댐호화된 하천의 조류 과다 발생원인과 해소 방안 - 낙동강 물금 지역의 수질 분석 데이터를 중심으로 - (Causes and Overcoming of the Algae Excess in a Dam Water - Based on the Data of Water Quality Analysis of Mulgum Area -)

  • 양시천;하첨첨;강태호
    • 한국환경복원기술학회지
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    • 제20권4호
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    • pp.1-13
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    • 2017
  • The purpose of this study is to analyze a term of decade of water quality data of the Mulgum intake station on the Nakdong river(dam) to find the cause of algal blooms and to set an alternative to prevent artificial lake water pollution. Our study shows that water quality changes have regular periodic regularity and there was a certain correlation between specific analytical items. According to the analysis results of each factor, the decline in precipitation was not the main reason for algal blooms. TP concentration had a slight effect on Chl-a concentration but was not a limiting nutrient of a bloom. TN concentration had a strong correlation with Chl-a and strongly negative correlation with temperature, but was not a bloom's limiting nutrient, and was only a dependent variable. As the temperature was negatively correlated with the Chl-a concentration, it is found that the aspect of the ecological influence of the temperature was the most important factor of the phytoplankton concentration change. The N/P ratio lies under a power function with a high degree of reliability by the TP concentration, and the phenomenon appeared to be the same as the results of two other comparative areas. This result confirms that TN is dependent on TP and the biota in the lake that TN is a dependent variable whose concentration is determined by TP it. In conclusion, the increase in lake bloom is the result of a food chain change, and it is necessary to control the ecosystem by the food chain in the lake in order to reduce the lake's bloom. In particular, it is important to keep the benthic ecosystem as wide as possible in the aerobic state.

소아 성장장애와 내분비에 대한 한의학적 고찰 (Study of Growth Disturbance and Endocrine, in the view of Oriental Medicine)

  • 전찬일
    • 대한한방소아과학회지
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    • 제15권1호
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    • pp.105-115
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    • 2001
  • The relation of endocrine in the western medicine and zangfu-organ functions in Korean medicine, related to growth disturbance, was studied and derived the following results. 1. The hormone most related to growth disturbance is, directly secreted from the anterior pituitary or is stimulated and secreted in the target grands, growth hormone, thyroid, adrenocortical hormone, gonadial hormone and is insulin secreted from $\beta$ cell of langerhans' slands of pancreas. 2. the pituitary has the most close relation with the kidney in the five zang-organ. Because the kidney is innate origin(先天之本) and promotes qi and blood(生化氣血), stores the essence of life(藏精), dominates the bones(主骨) and promotes the marrow(生骨髓). Especially it is connected with brain(通於腦). 3. In the children growth, the endocrine action in the pituitary has the most close relation with the kidney, As in the reports of the brain and spinal cord, bone, store essence of life, sexual maturation and decline(kidney-qi, sexual functions of both sexes(天癸)) etc, and cause of cretinism, dwarf in the main subject. 4. Somatomedin is the most important factor of the growth factors, IGF in another word. The unification of IGF and secretion is controlled firstly according to growth hormone, however is very closely related to the nutrition status in the non-hormonic causes. Also, it is affected very much by the insulin. 5. Insulin is one of the important hormone related to the growth and is secreted from the pancreas. Pancreas belongs to the functional system of spleen in oriental medicine, thus the growth disturbance, occurred due to error in insulin secretion and nutrition(in another words, the lack of postnatal essential substance from food-stuff(水穀精氣)), is closely related to the spleen. 6. From the results driven above, the hormone action of endocrine and problem in secretion, related to the growth disturbance, must be focused on the differentiation of symptoms and signs of the kidney and the spleen in oriental medicine.

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Sensing Technology for Rapid Detection of Phosphorus in Water: A Review

  • Islam, Sumaiya;Reza, Md Nasim;Jeong, Jin-Tae;Lee, Kyeong-Hwan
    • Journal of Biosystems Engineering
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    • 제41권2호
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    • pp.138-144
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    • 2016
  • Purpose: Phosphorus is an essential element for water quality control. Excessive amounts of phosphorus causes algal bloom in water, which leads to eutrophication and a decline in water quality. It is necessary to maintain the optimum amount of phosphorus present. During the last decades, various studies have been conducted to determine phosphorus content in water. In this study, we present a comprehensive overview of colorimetric, electrochemical, fluorescence, microfluidic, and remote sensing technologies for the measurement of phosphorus in water, along with their working principles and limitations. Results: The colorimetric techniques determine the concentration of phosphorus through the use of color-generating reagents. This is specific to a single chemical species and inexpensive to use. The electrochemical techniques operate by using a reaction of the analyte of interest to generate an electrical signal that is proportional to the sample analyte concentration. They show a good linear output, good repeatability, and a high detection capacity. The fluorescence technique is a kind of spectroscopic analysis method. The particles in the sample are excited by irradiation at a specific wavelength, emitting radiation of a different wavelength. It is possible to use this for quantitative and qualitative analysis of the target analyte. The microfluidic techniques incorporate several features to control chemical reactions in a micro device of low sample volume and reagent consumption. They are cheap and rapid methods for the detection of phosphorus in water. The remote sensing technique analyzes the sample for the target analyte using an optical technique, but without direct contact. It can cover a wider area than the other techniques mentioned in this review. Conclusion: It is concluded that the sensing technologies reviewed in this study are promising for rapid detection of phosphorus in water. The measurement range and sensitivity of the sensors have been greatly improved recently.

Cognitive Dysfunction and Hippocampal Damage Induced by Hypoxic-Ischemic Brain Injury and Prolonged Febrile Convulsions in Immature Rats

  • Byeon, Jung Hye;Kim, Gun-Ha;Kim, Joo Yeon;Sun, Woong;Kim, Hyun;Eun, Baik-Lin
    • Journal of Korean Neurosurgical Society
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    • 제58권1호
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    • pp.22-29
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    • 2015
  • Objective : Perinatal hypoxic-ischemic encephalopathy (HIE) and prolonged febrile seizures (pFS) are common neurologic problems that occur during childhood. However, there is insufficient evidence from experimental studies to conclude that pFS directly induces hippocampal injury. We studied cognitive function and histological changes in a rat model and investigated which among pFS, HIE, or a dual pathologic effect is most detrimental to the health of children. Methods : A rat model of HIE at postnatal day (PD) 7 and a pFS model at PD10 were used. Behavioral and cognitive functions were investigated by means of weekly open field tests from postnatal week (PW) 3 to PW7, and by daily testing with the Morris water maze test at PW8. Pathological changes in the hippocampus were observed in the control, pFS, HIE, and HIE+pFS groups at PW9. Results : The HIE priming group showed a seizure-prone state. The Morris water maze test revealed a decline in cognitive function in the HIE and HIE+pFS groups compared with the pFS and control groups. Additionally, the HIE and HIE+pFS groups showed significant hippocampal neuronal damage, astrogliosis, and volume loss, after maturation. The pFS alone induced minimal hippocampal neuronal damage without astrogliosis or volume loss. Conclusion : Our findings suggest that pFS alone causes no considerable memory or behavioral impairment, or cellular change. In contrast, HIE results in lasting memory impairment and neuronal damage, gliosis, and tissue loss. These findings may contribute to the understanding of the developing brain concerning conditions caused by HIE or pFS.