• Title/Summary/Keyword: Cause of Death

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The King Jeong-Jo's Sasang Constitution, Which wsa Based on the Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je jun Se(弘齋全書), GukSoBoGam(國朝寶鑑) (문헌을 통해 살펴 본 정조의 사상체질)

  • Kim, Dal-Rae;Kim, Sun-Hyung
    • Journal of Sasang Constitutional Medicine
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    • v.21 no.1
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    • pp.44-52
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    • 2009
  • 1. Objectives Jeong-Jo's death has many mistery. So we understand rightly Jeong-Jo's death. we inspect closely medical records of 20 days before death(in The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書), GukSoBoGam(國朝寶鑑). We understand medical treatment before death. It is based on Jeong-Jo's Constitution. So we trace the cause of a Jeong-Jo's death rightly. 2. Methods According to The Annals of the Choson Dynasty(朝鮮王朝實錄), Hong Je Jun Se(弘齋全書) GukSoBoGam(國朝寶鑑). We found out Jeoung-Jo's Sasang constitutional elemet. We point on Jeoung-Jo's nature and emotion, temperament and talent, features and way of speaking, physical appearance, healthy state, ordinary symptom, pathological syndromes and pharmacology. so documentary records was worthy of notice. 3. Results and conclusions 1. Jeong-Jo has prominent cheekbones,flat face. It belong to Tae-eum. 2. Jeong-Jo's physical appearance is mild,around,large. It belong ro Tae-eum. 3. Jeong-Jo's favorite food and herb were belong to Tae-eum interior febrile disease herb. which is Exhale Dispersing Qi 4. So even though Jeoung-Jo is Tae-eum, He had a weak body. It main cause that Smoking, insomnia, heave work, Hwa disease. 5. Jeong-Jo's is Interior febrile disease induced form the liver affected by heat in Tae-eumin

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Prognostic Value of Dual-Energy CT-Based Iodine Quantification versus Conventional CT in Acute Pulmonary Embolism: A Propensity-Match Analysis

  • Dong Jin Im;Jin Hur;Kyunghwa Han;Young Joo Suh;Yoo Jin Hong;Hye-Jeong Lee;Young Jin Kim;Byoung Wook Choi
    • Korean Journal of Radiology
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    • v.21 no.9
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    • pp.1095-1103
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    • 2020
  • Objective: The present study aimed to investigate whether quantitative dual-energy computed tomography (DECT) parameters offer an incremental risk stratification benefit over the CT ventricular diameter ratio in patients with acute pulmonary embolism (PE) by using propensity score analysis. Materials and Methods: This study was conducted on 480 patients with acute PE who underwent CT pulmonary angiography (CTPA) or DECT pulmonary angiography (DE CT-PA). This propensity-matched study population included 240 patients with acute PE each in the CTPA and DECT groups. Altogether, 260 (54.1%) patients were men, and the mean age was 64.9 years (64.9 ± 13.5 years). The primary endpoint was all-cause death within 30 days. The Cox proportional hazards regression model was used to identify associations between CT parameters and outcomes and to identify potential predictors. Concordance (C) statistics were used to compare the prognoses between the two groups. Results: In both CTPA and DECT groups, right to left ventricle diameter ratio ≥ 1 was associated with an increased risk of all-cause death within 30 days (hazard ratio: 3.707, p < 0.001 and 5.573, p < 0.001, respectively). However, C-statistics showed no statistically significant difference between the CTPA and DECT groups for predicting death within 30 days (C-statistics: 0.759 vs. 0.819, p = 0.117). Conclusion: Quantitative measurement of lung perfusion defect volume by DECT had no added benefit over CT ventricular diameter ratio for predicting all-cause death within 30 days.

Analysis on the Actual Conditions of Deaths due to Fires based on Annual Report on the cause of Death Statistics in Korea (사망원인통계연보에 기초한 화재로 인한 사망자발생 실태 분석)

  • Lee, Eui-Pyeong
    • Fire Science and Engineering
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    • v.20 no.1 s.61
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    • pp.98-103
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    • 2006
  • This paper analyzed deaths caused by fires using the Annual Report on the Cause of Death Statistics (based on vital registration) published by the Korea National Statistical Office. The number of fire deaths and the fire death rates of all deaths have started to decrease since the height in 1993. The younger groups have increasingly more fire deaths than the older groups. While children groups(age 10 and under) have decreased in their deaths caused by fires, the older groups (65 and over) tend to increase. Males are more likely to have a risk than females in all age groups. Fire death rates per 100,000 populations by age group suggest very high rates in the older groups. Although there are few changes in death rates caused by fires of all deaths, young children (age 4 and under) and older adults (age 75 and over) have a higher risk than any other age groups.

Analysis of the Factors and Patterns Associated with Death in Aircraft Accidents and Incidents Using Data Mining Techniques (데이터 마이닝 기법을 활용한 항공기 사고 및 준사고로 인한 사망 발생 요인 및 패턴 분석)

  • Kim, Jeong-Hun;Kim, Tae-Un;Yoo, Dong-Hee
    • Journal of Digital Convergence
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    • v.17 no.9
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    • pp.79-88
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    • 2019
  • This study analyzes the influential factors and patterns associated with death from aircraft accidents and incidents using data mining techniques. To this end, we used two datasets for aircraft accidents and incidents, one from the National Transportation Safety Board (NTSB) and the other from the Federal Aviation Administration (FAA). We developed our prediction models using the decision tree classifier to predict death from aircraft accidents or aircraft incidents and thereby derive the main cause factors and patterns that can cause death based on these prediction models. In the NTSB data, deaths occurred frequently when the aircraft was destroyed or people were performing dangerous missions or maneuver. In the FAA data, deaths were mainly caused by pilots who were less skilled or less qualified when their aircraft were partially destroyed. Several death-related patterns were also found for parachute jumping and aircraft ascending and descending phases. Using the derived patterns, we proposed helpful strategies to prevent death from the aircraft accidents or incidents.

Cellular and Molecular Pathways of Ischemic Neuronal Death

  • Won, Seok-Joon;Kim, Doo-Yeon;Gwag, Byoung-Joo
    • BMB Reports
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    • v.35 no.1
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    • pp.67-86
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    • 2002
  • Three routes have been identified triggering neuronal death under physiological and pathological conditions. Excess activation of ionotropic glutamate receptors cause influx and accumulation of $Ca^{2+}$ and $Na^+$ that result in rapid swelling and subsequent neuronal death within a few hours. The second route is caused by oxidative stress due to accumulation of reactive oxygen and nitrogen species. Apoptosis or programmed cell death that often occurs during developmental process has been coined as additional route to pathological neuronal death in the mature nervous system. Evidence is being accumulated that excitotoxicity, oxidative stress, and apoptosis propagate through distinctive and mutually exclusive signal transduction pathway and contribute to neuronal loss following hypoxic-ischemic brain injury. Thus, the therapeutic intervention of hypoxic-ischemic neuronal injury should be aimed to prevent excitotoxicity, oxidative stress, and apoptosis in a concerted way.

An update on immunotherapy with PD-1 and PD-L1 blockade

  • Koh, Sung Ae
    • Journal of Yeungnam Medical Science
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    • v.38 no.4
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    • pp.308-317
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    • 2021
  • Cancer is the leading cause of death and is on the rise worldwide. Until 2010, the development of targeted treatment was mainly focused on the growth mechanisms of cancer. Since then, drugs with mechanisms related to tumor immunity, especially immune checkpoint inhibitors, have proven effective, and most pharmaceutical companies are striving to develop related drugs. Programmed cell death-1 and programmed cell death ligand-1 inhibitors have shown great success in various cancer types. They showed durable and sustainable responses and were approved by the U.S. Food and Drug Administration. However, the response to inhibitors showed low percentages of cancer patients; 15% to 20%. Therefore, combination strategies with immunotherapy and conventional treatments were used to overcome the low response rate. Studies on combination therapy have typically reported improvements in the response rate and efficacy in several cancers, including non-small cell lung cancer, small cell lung cancer, breast cancer, and urogenital cancers. The combination of chemotherapy or targeted agents with immunotherapy is one of the leading pathways for cancer treatment.

An Empirical Review of the Relationship between Schooling and Demand for Children on the Basis of Quantity-Quality Interaction Model (자녀교육과 수요간의 상관관계에 관한 실증적 고찰)

  • Chang-Jin Moon
    • Korea journal of population studies
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    • v.11 no.1
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    • pp.197-203
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    • 1988
  • In order to examine cause-specific mortality in Korea by comparing mortality of Japan, various mortality indicators are calculated using 1995 of ficial statistics of twonations. The mortality measures are cause-specific mortality rate by sex, age, andmarital status, cause-specific age-standardized death rate and potential years of lifelost, and their ratios by sex and nation. Items of major causes of death include allcauses (total deaths),tuberculosis, malignant neoplasm, diabetes mellitushypertensive diseases, heart diseases, cerebrovascular diseases, liver diseasestransport accidents, and suicide. Major characteristics of mortality in Korea are asfollows . (1) Death rates from most causes except suicide are higher in Korea thanJapan and especially death rates from tuberculosis, hypertensive diseases, liverdiseases, and transport accidents are higher for economically active Koreans : (2)Death rates from tuberculosis, liver diseases, transport accidents, and malignantneoplasm are salient for Korean children (3) Sex-differentials in mortality fromliver diseases, tuberculosis , and transport accidents are large for economically activeKoreans, because male mortality is higher than female mortality : (4) Suicide ratesare lower for economically active males, and higher for females aged 10s and 20s inKorea than Japan : (5) Death rates are highest f3r divorced or widowed under 45years of age depending on causes, but death rates from all causes are highest fornever-married of the age 45 and over in Korea : and (6) Sex-differentials inmortality are greatest for widowed in Korea and for divorced in Japan.

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Improve the Administrative Death Investigation System (행정검시제도 개선방안)

  • Kim, Heon-Jin
    • The Journal of the Korea Contents Association
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    • v.12 no.2
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    • pp.276-283
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    • 2012
  • Current Administrative Death investigation system is have many problems. Almost local governor don't exercise about administrative death investigation authority. Thus, prosecutors have to many decisions about judicial death investigation authority. Consequently, these vicious cycle is repeated. There is not clear regulations about scope for judicial death investigation. Discussed in this paper improve the Administrative Death investigation system are as follows : First, the uniform act of death investigation is have to legislated. Second, the scope for death investigation is clearly legalized. Medical examiner is must administrative death investigation according to the law. Also prosecutor can order to judicial autopsy to medic examiner. Third, Administrative Death investigation rules should be clarified. Introduce a Medical Examiner System Korean Administrative Death Investigation system centered on prosecutor and judicature who are not a specialist in pathology or forensic medicine. Lacking in professional understanding cause less accuracy of Administrative Death Investigation. To overcome limitations and problems of our Administrative Death Investigation system is suggested to introduce a Medical Examiner system.

The effect of education on 'how to write the death certificate' for resident trainees of the emergency department (전공의를 대상으로 시행한 사망진단서 작성법 교육의 효과)

  • Kang, Eunjin;Lee, Hyeji;Kim, Sun Hyu
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.529-550
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    • 2018
  • Objective: This study investigated the most common errors on death certificates written by resident trainees of the emergency department and evaluated the effects of education on how to write a death certificate. Methods: A casebook of 31 deaths was prepared based on actual death cases in the emergency room in 2016. Ten residents completed 31 death certificates for the death casebook without any prior notice and then received education on 'How to write the death certificate.' They completed the death certificates again for the same casebook after receiving the education and the number of errors on all death certificates was again determined and divided into major and minor errors. The average number of error types was compared before and after the education. Results: Major errors occurred in 55% of all death certificates, but decreased to 32% after education. Minor errors decreased from 81% before education to 54% after education. The most common major error was 'unacceptable cause of death' (mean${\pm}$standard deviation [SD], $10.2{\pm}8.2$), and the most common minor error was 'absence of time interval' (mean${\pm}$SD, $24.0{\pm}7.7$), followed by 'absence of other significant conditions' (mean${\pm}$SD, $14.6{\pm}6.1$) before education. Conclusion: Education on 'how to write a death certificate' can help reduce errors on death certificates and improve the quality of death certificates.