• Nutrition Research and Practice
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• v.11 no.5
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• pp.419-429
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• 2017

BACKGROUND/OBJECTIVES: The relationship between folate and colorectal neoplasia remains controversial. We examined the association between serum folate concentrations and colorectal adenomas in a case-control study of Korean adults and conducted a meta-analysis. SUBJECTS/METHODS: Our case-control study included 113 pairs of case and control who underwent colonoscopy and provided blood samples. We used multivariable conditional logistic regression models to obtain the odds ratios and 95% confidence interval (CIs). For meta-analysis, we identified the relevant studies by searching the PubMed database up to February 2017, included our case-control study and combined the study-specific relative risks (RRs) using a random-effects model. RESULTS: In this case-control study, we included 58 men and 55 women with colorectal adenomas and sex and fasting status matched the controls. We did not find any significant association between the serum folate levels and colorectal adenomas in either men or women. For meta-analysis, a total of eleven studies were included in our analysis and classified into two groups; polyp clearance group (PC) for the studies that included participants who underwent endoscopies and had their polyps removed at baseline; and no polyp clearance group (NPC) for the studies that included participants whose histories of endoscopies were unknown or who underwent their first endoscopies. Four PC (1,311 cases and 1,672 non-cases) and eight NPC studies (3,501 cases and 11,347 non-cases) were included. The combined RRs (95% CIs) comparing the bottom with the top categories of circulating folate levels were 1.07 (0.97-1.18) for the NPC group but 1.45 (1.16-1.74) for the PC group. CONCLUSIONS: Low circulating folate levels were associated with new adenoma formation.

• Journal of Environmental Impact Assessment
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• v.9 no.3
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• pp.203-214
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• 2000

Health risk assessment is applied to streamlining LCA(Life Cycle Assessment) using Monte carlo simulation for probabilistic/stochastic exposure and risk distribution analysis caused by data variability and uncertainty. A case study was carried out to find benefits of this application. BTC(Benzene, Trichloroethylene, Carbon tetrachloride mixture alias) personal exposure cases were assumed as production worker(in workplace), manager(in office) and business man(outdoor). These cases were different from occupational retention time and exposure concentration for BTC consumption pattern. The result of cancer risk in these 3 scenario cases were estimated as $1.72E-4{\pm}1.2E+0$(production worker; case A), $9.62E-5{\pm}1.44E-5$(manger; case B), $6.90E-5{\pm}1.16E+0$(business man; case C), respectively. Portions of over acceptable risk 1.00E-4(assumed standard) were 99.85%, 38.89% and 0.61%, respectively. Estimated BTC risk was log-normal pattern, but some of distributions did not have any formal patterns. Except first impact factor(BTC emission quantity), sensitivity analysis showed that main effective factor was retention time in their occupational exposure sites. This case study is a good example to cover that LCA with probabilistic risk analysis tool can supply various significant information such as statistical distribution including personal/environmental exposure level, daily time activity pattern and individual susceptibility. Further research is needed for investigating real data of these input variables and personal exposure concentration and application of this study methodology.

• Journal of KIISE:Computer Systems and Theory
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• v.27 no.5
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• pp.506-517
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• 2000

In distributed real-time system, a task activated by the completion of its preceding task can be modeled as a periodic task with activation jitter. An activation jitter of a task is defined asthe difference between the worst case and the best case response time of its preceding task. Becausethe existing approaches assume that the best case response time is much smaller than the actual one,the activation jitter and the worst case response time of lower priority tasks are overestimated. Thispaper proposes a new analysis technique to calculate the best case response time more precisely andto reduce the activation jitter bounds. The proposed technique obtains the best case response time byconsidering the relative phase between tasks. The precise analysis of the activation jitters can reducethe worst case response time of other tasks and increase the schedulability. The simulation resultsshow that the proposed analysis technique improves the accuracy of the best case and the worst caseresponse time up to 40% and 6%, respectively.

• Journal of the Korean Society of Industry Convergence
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• v.2 no.2
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• pp.35-39
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• 1999

Results of two-part wedge analysis and centrifuge test executed by Zornberg et al. were compared for geotextile-reinforced slope stability. For two-part wedge analysis results of two cases, a frictional case considering internal friction of soil as interwedge friction and a nonfrictional case not considering, were also compared and evaluated. The analysis was based on limit equilibrium and two-part wedge was divided into slices as many as the number of geotextiles to obtain a maximum tension distribution mobilized in reinforcements. A significant observation was that the distribution was a triangular shape with maximum tension of geotextile at a transit point of interwedge. The number of geotextiles and failure surface of frictional case were reasonable and more comparable to results of the centrifuge tests than those of nonfrictional case. Therefore it can be said that two-part wedge analysis is recommendable for design analysis of reinforced slopes if an interwedge angle is regarded to be an angle of internal friction in soil.

• Current Research on Agriculture and Life Sciences
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• v.26
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• pp.17-22
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• 2008

This research put most emphasis on setting the guidelines for improvement through character analysis of landscape ecology to cope with ecological malfunction of the woodland surrounded in cultivated areas. The results are as follows. 1) As a result of character analysis of the woodland in cultivated area in point of landscape ecology in five case sites, the size of case site 3 is the largest as $3,000m^2$ and it is shown that a colony of pine trees which is valuable in terms of ecological, scientific, historic and cultural senses. 2) As a result of analysis on expansibility of woodland in cultivated area, case site 1 is 0.25, the lowest, flexibility is 4, the highest. In order to improve ecological function in woodland, it is regarded that maintaining curve form rather than straight one. 3) As a result of analysis of morphological diversity, case site 5 shows 1.3, the highest. However, the condition of vegetation and emergence frequency of species indicates low value degree. 4) Based on the result of analysis of landscape ecological character like above, the number of guidelines for the woodland in cultivated area is three and vegetation is four.

• Genomics & Informatics
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• v.20 no.3
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• pp.28.1-28.7
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• 2022

We described a clinical, laboratory, and genetic presentation of a pathogenic variant of the CYP1B1 gene through a report of a case of primary congenital glaucoma and a trio analysis of this candidate variant in the family with the Sanger sequencing method and eventually completed our study with the secondary/incidental findings. This study reports a rare case of primary congenital glaucoma, an 8-year-old female child with a negative family history of glaucoma and uncontrolled intraocular pressure. This case's whole-exome sequencing data analysis presents a homozygous pathogenic single nucleotide variant in the CYP1B1 gene (NM_000104:exon3:c.G1103A:p.R368H). At the same time, this pathogenic variant was obtained as a heterozygous state in her unaffected father but not her mother. The diagnosis was made based on molecular findings of whole-exome sequencing data analysis. Therefore, the clinical reports and bioinformatics findings supported the relation between the candidate pathogenic variant and the disease. However, it should not be forgotten that primary congenital glaucoma is not peculiar to the CYP1B1 gene. Since the chance of developing autosomal recessive disorders with low allele frequency and unrelated parents is extraordinary in offspring. However, further data analysis of whole-exome sequencing and Sanger sequencing method were applied to obtain the type of mutation and how it was carried to the offspring.

• Knowledge Management Research
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• v.21 no.3
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• pp.215-228
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• 2020

This study introduces the case of a company that newly jumped into the competitive cosmetics market with a brand concept developed through big data analysis. Skin Reverse Lab, which possesses anti-aging material technology, launched a new brand in the skincare cosmetics market. Using a big data analysis program called Luminoso, SNS data was analyzed in four areas, which were consumer attitudes toward overall cosmetics, skincare products, competitors, and consumers' experiences of product use. The age groups and competitors were analyzed through the emotional analysis technique including context, which is the strength of Luminoso, and insights on consumers were derived through the related word analysis and word cloud techniques. Based on the analysis results, Logically Skin have won various awards in famous magazines and apps, and have been recognized as products that meet global trend standards. Besides, it has entered six countries including the United States and Hong Kong. The Logically Skin case is a case in which a new company entered the market with a new brand by deriving consumer insights only from external data, and it is significant as a case of applying AI-based sentiment analysis.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.05a
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• pp.196-199
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• 2009

The most important thing is to analyze the Fast Cook Off problem of the solid motor case exposed to direct flame is a heat transfer analysis. Heat causes degradation and ignition of the propellant. To archive an acceptable reaction level in Fast Cook Off, the rocket motor case generally must fail structurally prior to propellant ignition. We investigate the responses of the solid motor case exposed to Fast Cook Off by using finite element method for the thermal analysis.

• Land and Housing Review
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• v.10 no.1
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• pp.25-32
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• 2019

In this study, the case analysis data on underground temperature are presented. In addition, numerical analysis of the ventilation load reduction plan was derived according to the residence schedule change for the building with cool tube. The research scope and method are as follows. The overall system principle was examined through reviewing the theory of the Cool tube system. Case study and analysis were conducted. Numerical simulation was used to examine the change in energy usage. Also, the change of load energy in case of varying amount of ventilation was derived based on actual building room schedule. When the Cool tube system was applied to the residential buildings, the cooling load was reduced from 3,331 kW to 193 kW, which showed a reduction effect of about 90%.The heating load was reduced from 42,276kW to 32,575kW by 23%.Also, result shows that the cooling load decreased by 24% and the heating load decreased by 66% when the number of ventilation according to the occupancy schedule was applied.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.25 no.3
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• pp.390-398
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• 2001

Welding process generates distortion and residual stress in the weldment due to rapid heating and cooling. Welding distortion and residual stress in the welded structure result in many troubles such as dimensional inaccuracies in assembling and safety problem during service. The accurate prediction of welding residual stress is thus very important to improve the quality of weldment and find the way to reduce itself. This paper suggests new analysis method to predict welding residual stress by considering solid phase transformation during welding process. Using the method, analysis is performed for medium and low carbon steel. The analysis result for medium carbon steel reveals that case considering phase transformation has compressive residual stress in contrast with the case neglecting phase transformation because of martensite formation. However, for the case of low carbon steel, residual stress shows little difference between the case considering phase transformation and the other case, because it has small transformation strain and recovers rapidly stress after phase transformation.