• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.27 no.3
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• pp.178-183
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• 2014

Recently, various type of nanomaterials such as nanorod, nanowire, nanotube and their core/shell nanostructures have attracted much attention in photocatalyst due to their unique properties. Among them, Type-II core/shell heterostructures have extensively studied because it has exhibited improved electrical and optical properties against their single-component nanostructure. Such structures are expected to offer high absorption efficiency and fast charge transport due to their stepwised energetic combination and large internal surface area. Thus, it has been considered as potential candidates for high efficient photocatalytic activity. In this work, we introduce a novel chemical conversion process to synthesize Type-II ZnO/ZnSe core/shell heterostructures. A plausible conversion mechanism to ZnO/ZnSe core/shell heterostructres was proposed based on SEM, XRD, TEM and XPS analysis. The ZnO/ZnSe heterostructures exhibited excellent photocatalytic activity toward the decomposition of RhB dye compared to the ZnO nanorod arrays due to enhanced light absorption and the type-II cascade band structure.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.7
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• pp.1010-1021
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• 1999

In this paper, error performance of DS/CDMA GMSK system has been analyzed in a radio channel which is characterized by multi-user interference(MUI) and Nakagami fading. The DS/CDMA GMSK system adopts Maximum Ratio Combining(MRC) diversity and co-channel interference (CCI) to enhance system performance. Using the derived error probability equation, the error performance of DS/CDMA GMSK system has been evaluated and shown in figures to discuss as a function of PN code length(N), number of multi-user(K), number of diversity branch(L), and bit energy per noise power ratio ($E_b/N_0$), fading index(m). The results show that there is a substantial enhancement in performance by employing an MRC diversity or a CCI canceller. Additional improvement can be obtained when the MRC diversity and the CCI canceller are adopted in cascade form. Consequently, we expected that proposed system structure is reliable to the voice communication system in Nakagami fading, multi-user interferences and multipath channel.

• Journal of Lipid and Atherosclerosis
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• v.7 no.2
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• pp.122-154
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• 2018

Familial hypercholesterolemia (FH) is typically associated with single gene mutation that is inherited by autosomal dominant manner. Due to high cardiovascular risk, aggressive discovery, diagnosis, and treatment of FH are critical. Although FH is being increasingly spotlighted, we do not have sufficient data on Korean patients with FH. Here, we present the content of symposium of the Education Committee, Korean Society of Lipid and Atherosclerosis held in May 2018: 1) epidemiology, clinical diagnosis, Korean FH data, and regulation in Korea; 2) genes associated with FH, sequencing process in suspicious proband, cascade screening, and difficulty in genetic diagnosis in FH; 3) the importance of lipid-lowering therapy in FH, conventional and novel therapeutics for FH; 4) diagnosis of FH in children and adolescence, screening, and treatment of FH in children and adolescence; 5) history of FH studies in Korea, the structure and current status of FH registry of Korean Society of Lipid and Atherosclerosis; and 6) difficulty in diagnosis of heterozygous and homozygous FH, drug intolerance and achievement of treatment target. Discussion between speakers and panels were also added. We hope that this article is helpful for understanding FH and future studies performed in Korea.

• Journal of Korea Port Economic Association
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• v.27 no.1
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• pp.281-304
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• 2011

In the energy-climate era, pollution emissions from port activities have a significant issue in international shipping and port community. Thus international organization such as IMO and developed countries are seeking to develop various reduction strategies against air pollution. However Korea has recently conducted several studies concerning air pollution in port industry. The main purpose of the paper is to suggest emission reduction strategies for bulk terminal in Port of Incheon, which handles large amount bulk cargoes as a gateway for the metropolitan area. For this aim, the clean air strategies of the world major ports were considered and air pollution reduction strategies were suggested. The main findings of this paper are as follows. First, the emission reduction strategies for container terminal are should be integrated based on technologies changes, operational changes and market-based measures. Second, the emission reduction strategies for bulk terminal can be effective when use innovative measures during loading, unloading and storage process such as telescopic cascade trimming chute, snake sandwich equipment, dry fog system and dome structure. Finally, investigation on actual conditions of air pollution in Korean ports and development of environmental evaluation scheme for persisting monitoring should be conducted.

• Land and Housing Review
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• v.6 no.2
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• pp.89-99
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• 2015

What is a role of the studies on spatial planning of Korean peninsular and its cities in the process of cooperation between and unification of South and North Korea? Where should the basic perspectives be oriented for the process? Can a comprehensive plan of North Korea have practical implications although South-North cooperation does not get into its stride? If it can, which contents should the plan cover? This study aims to contemplate these issues and to suggest a preliminary land development approach of North Korea, which would contribute academic and practical debates on the issues, at this juncture of the cascade of studies on spatial planning in North Korea. It assume South-North relation would evolve from 'reconciliation and cooperation' and 'confederation' into 'unification' of South and North Korea which is based on the official plan of South Korea. We suggest, as the basic perspectives of development approach, cooperation(or co-evolution), future-oriented sustainability, and parallel development of industry and physical infrastructure. The development potential of North Korea is explained by detail fields and sub-regions, which is used to analyse SWOT and to subsequently extract the basic directions(vision and strategies) of North Korea development. These directions are followed by the spatial structure plan to improve North Korea using the potential of the regions. Based on the plan, the development directions of detail fields are suggested.

• Clinical and Experimental Pediatrics
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• v.52 no.6
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• pp.696-700
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• 2009

Purpose : We screened more than 350 compounds with an endoperoxide ring structure in search of an anti-leukemic drug and found that compound 127 (c-127) could induce significant cytotoxicity in HL-60 cells. In this study, we investigated the molecular mechanisms of compound 127-induced antitumor activity on HL-60 cells. Methods : HL-60 cells were cultured in Rosewell Park Memorial Institute 1640 and cell viability was measured by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], a tetrazole assay. Apoptosis was assessed by a DNA fragmentation test. Apoptotic machineries were determined by Western blot analysis. Results : C-127 could induce a cytotoxic effect at 24 h and apoptosis at 6 h, which was demonstrated with MTT assay and DNA fragmentation test, respectively. The apoptotic effect of this drug was caused by the activation of the intracellular caspase-8,3 activation, the cleavage of pro-apoptotic Bid, and the increase of c-Jun expression accompanied with JNK (Jun N-terminal kinases) phosphorylation. On the contrary, it increased the expression of anti-apoptotic Bcl-2 levels, leading to the induction of the induction of anti-apoptotic effect. Taken together, the present study demonstrated that c-127 was a potent inducer of cytotoxicity on HL-60 cells through apoptotic mechanisms, which included the activation of caspase family, the regulation of Bcl-2 family, and the activation of JNK signaling pathway. Conclusion : Our results suggest that c-127 has a strong antitumor activity through the regulation of various apoptotic machineries on HL-60 cells. The compound may be utilized as an effective and potentially therapeutic drug in leukemia.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.3
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• pp.269-281
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• 2014

In this paper, a systematic design of a low phase noise voltage-tuned dielectric resonator oscillator(VTDRO) using loop group delay is proposed. Designed VTDRO is closed-loop type and consists of a cascade connection of a resonator, phase shifter, and amplifier. Firstly, a reference VTDRO is fabricated and its phase noise and electrical frequency tuning range are measured. Both the phase noise and electrical frequency tuning range depend on the loop group delay. Then, a required value of loop group delay for a new VTDRO with a low phase noise can be systematically computed. In addition, its phase noise and electrical frequency tuning range can be theoretically estimated using those obtained from the measurement of the reference VTDRO. When the loop group delay increases, the phase noise decreases and the electrical frequency tuning range also decreases. The former predominantly depends on the resonator structure. Therefore we propose a systematic design procedure of a resonator with high group delay characteristics. The measured loop group delay of the new VTDRO is about 700 nsec. The measured phase noise of the new VTDRO show a state-of-the-art performance of 154.5 dBc/Hz at 100 kHz frequency offset and electrical frequency tuning range of 448 kHz for a voltage change of 0~10V. The oscillation power is about 4.39 dBm.

• Korean Journal of Environmental Agriculture
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• v.35 no.1
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• pp.39-45
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• 2016

BACKGROUND: This study aimed to evaluate the combined effects of three components (NPK) of chemical fertilizers with basal application of compost on soil organisms.METHODS AND RESULTS: The soil was treated with five treatments continuously for 15 years: control, PK, NK, NP and NPK. The application of N increased plant growth or biomass, and enhanced organic matter content in the soils. Levels of microbial phospholipid fatty acids (PLFAs) in the soils did not show marked differences among the soils treated with different treatments. However, the principal component analysis showed the changes in the structure of the microbial community in the soil, depending on treatments added. Nitrogen application caused a decrease of pH and an increase of EC in the soils, and these environmental stresses appeared to offset the promoting effect of increased organic matter content on microbial abundance. The abundance of bacterivorous nematodes was the highest in the soils after treating NPK; however, the abundance of fungivorous nematodes was unaffected. There was no significant correlation between the abundances of microbial groups and their feeders. Organic matter content was significantly correlated with the abundance of nematodes in the soils.CONCLUSION: Our results showed that chemical fertilizers affect the soil food chains through both biotic and abiotic factors, and a trophic cascade in the soils may not occur in response to long-term fertilization.

• KIPS Transactions on Software and Data Engineering
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• v.3 no.9
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• pp.361-368
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• 2014

The LPR(License plate recognition) system has been developed to efficient control for complex traffic environment and currently be used in many places. However, because of light, noise, background changes, environmental changes, damaged plate, it only works limited environment, so it is difficult to use in real-time. This paper presents a heuristic segmentation algorithm for robust to noise and illumination changes and introduce a real-time license plate recognition system using it. In first step, We detect the plate utilized Haar-like feature and Adaboost. This method is possible to rapid detection used integral image and cascade structure. Second step, we determine the type of license plate with adaptive histogram equalization, bilateral filtering for denoise and segment accurate character based on adaptive threshold, pixel projection and associated with the prior knowledge. The last step is character recognition that used histogram of oriented gradients (HOG) and multi-layer perceptron(MLP) for number recognition and support vector machine(SVM) for number and Korean character classifier respectively. The experimental results show license plate detection rate of 94.29%, license plate false alarm rate of 2.94%. In character segmentation method, character hit rate is 97.23% and character false alarm rate is 1.37%. And in character recognition, the average character recognition rate is 98.38%. Total average running time in our proposed method is 140ms. It is possible to be real-time system with efficiency and robustness.

• Korean Journal of Food Science and Technology
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• v.50 no.3
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• pp.349-355
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• 2018

Ginsenoside Rg5, one of the protopanaxadiol ginsenosides of wood-cultivated ginseng, has been implicated in various diseases, such as diabetes, cancer, and hypertension; however, its angiogenic activity and molecular mechanisms have not yet been elucidated. Here, we found that wood-cultivated ginseng extract and ginsenoside Rg5 increase in vitro proliferation, migration, and tube-like structure formation, which are typical phenomena associated with angiogenesis, in cultured human umbilical vein endothelial cells (HUVECs). Moreover, Ginsenoside Rg5 stimulated the phosphorylation of Akt, endothelial nitric oxide (NO) synthase (eNOS), and extracellular-regulated kinase (ERK)1/2, which are well-known signal mediators of the angiogenic pathway. Furthermore, Ginsenoside Rg5 did not accelerate the activation of ICAM-1 and VCAM-1 which are inflammatory response mediators. These results suggest that wood-cultivated ginseng extract and ginsenoside Rg5 stimulated in vitro angiogenesis by activating the Akt/eNOS- and ERK1/2-dependent signal pathways without inducing vascular inflammation.