• BMB Reports
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• 제43권2호
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• pp.103-109
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• 2010

Modification of proteins by the reversible covalent addition of the small ubiquitin like modifier (SUMO) protein has important consequences affecting target protein stability, sub-cellular localization, and protein-protein interactions. SUMOylation involves a cascade of enzymatic reactions, which resembles the process of ubiquitination. In this study, we characterized the SUMOylation system from an important crop plant, rice, and show that it responds to cold, salt and ABA stress conditions on a protein level via the accumulation of SUMOylated proteins. We also characterized the transcriptional regulation of individual SUMOylation cascade components during stress and development. During stress conditions, majority of the SUMO cascade components are transcriptionally down regulated. SUMO conjugate proteins and SUMO cascade component transcripts accumulated differentially in various tissues during plant development with highest levels in reproductive tissues. Taken together, these data suggest a role for SUMOylation in rice development and stress responses.

• BMB Reports
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• 제51권3호
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• pp.134-142
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• 2018

Organ growth is fundamental to animal development. One of major mechanisms for growth control is mediated by the conserved Hippo signaling pathway initially identified in Drosophila. The core of this pathway in Drosophila consists of a cascade of protein kinases Hippo and Warts that negatively regulate transcriptional coactivator Yorkie (Yki). Activation of Yki promotes cell survival and proliferation to induce organ growth. A key issue in Hippo signaling is to understand how core kinase cascade is activated. Activation of Hippo kinase cascade is regulated in the upstream by at least two transmembrane proteins Crumbs and Fat that act in parallel. These membrane proteins interact with additional factors such as FERM-domain proteins Expanded and Merlin to modulate subcellular localization and function of the Hippo kinase cascade. Hippo signaling is also influenced by cytoskeletal networks and cell tension in epithelia of developing organs. These upstream events in the regulation of Hippo signaling are only partially understood. This review focuses on our current understanding of some upstream processes involved in Hippo signaling in developing Drosophila organs.

• International Journal of Fluid Machinery and Systems
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• 제9권4호
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• pp.362-369
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• 2016

The shock-free inflow criterion applied in the development of two-dimensional cascade for turbomachinery design. The developed cascade analysis with potential flow calculation through a panel method has been used to determine the shock-free inflow condition. The combination between cascade analysis and PSO (particle swarm optimization) algorithm provides an opportunity to develop a diagram of a two-dimensional parameter cascade at various airfoil shapes. Analytical equations have been derived from the diagram that will facilitate the turbomachinery designer in applying the shock-free inflow criterion on their developed cascade. This method has been used to develop the very low head axial hydraulic turbine and provides excellent results of numerical and actual prototype performances.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.1975-1980
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• 2004

The three-dimensional flow in a turbine nozzle guide vane passage causes large secondary loss through the passage and increased heat transfer on the blade surface. In order to reduce or control these secondary flows, a linear cascade with a contoured endwall configuration was used and changes in the three-dimensional flow field were analyzed and discussed. Measurements of secondary flow velocity and total pressure loss within the passage have been performed by means of five-hole probes. The investigation was carried out at fixed exit Reynolds number of $4.0{\times}10^5$. The objective of this study is to document the development of the three-dimensional flow in a turbine nozzle guide vane cascade with modified endwall. The results show that the development of passage vortex and cross flow in the cascade composed of one flat and one contoured endwalls are affected by the flow acceleration which occurs in contoured endwall side. The overall loss is reduced near the flat endwall rather than contoured endwall.

• 한국소음진동공학회논문집
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• 제19권7호
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• pp.719-725
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• 2009

An efficient time-domain numerical method for the analysis of broadband noise generation and propagation due to turbulence-cascade interaction is developed. The core algorithm of the present method is based on the B-periodicity of the acoustic response function of the flat-airfoil cascade to the ingesting gust(B denotes the number of airfoils in the cascade). To confirm this periodicity, gust-cascade interaction problem are solved by using the time-domain method, which shows that the incident gust with the circumferential mode number having the same remainders when divided by the airfoil number excites the same acoustic response of the cascade. Using the proposed fast algorithm with this periodicity, we show that the total computation time for the model broadband problem using the total 525 incident gust modes can be reduced to about 1/4 of that taken in using the previous time-domain program.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2009년도 춘계학술대회 논문집
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• pp.477-482
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• 2009

An efficient time-domain numerical method for the analysis of broadband noise generation and propagation due to turbulence-cascade interaction is developed. The core algorithm of the present method is based on the B-periodicity of the acoustic response function of the flat-airfoil cascade to the ingesting gust (B denotes the number of airfoils in the cascade). To confirm this periodicity, gust-cascade interaction problem are solved by using the time-domain method, which shows that the incident gust with the circumferential mode number having the same remainders when divided by the airfoil number excites the same acoustic response of the cascade. Using the proposed fast algorithm with this periodicity, we show that the total computation time for the model broadband problem using the total 525 incident gust modes can be reduced to about 1/4 of that taken in using the previous time-domain program.

• Journal of Advanced Marine Engineering and Technology
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• 제16권4호
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• pp.78-87
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• 1992

The experimental study and theoretical analysis are made in order to investigate a new refrigeration system, R-22 and R-502 or R-13 cascade compressor with panel type cooler, for tuna long liner. The experimental apparatus consists with the cascade unit, 1.5 HP R-502 compressor in the first stage and 1 HP R-22 compressor in the second stage, and 3 $m^2$ cold storage room with a direct expansion panel type cooler. The main result are as follows: 1. The energy saving and C.O.P. of the R-22 and R-502 or R-22 and R-13 cascade are improved much higher than two stage compressor. 2. For the point of simplicity of design, installation, and running cost, the panel type cooler is much better than traditional hair pin coil type cooler. 3. From the experimental data and analysis, the R-22 and R-502, or R-22 and R-13 cascade compressor with panel type cooler is recommended for a new refrigeration equipment of the tuna long liner.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2016년도 춘계학술발표대회
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• pp.700-703
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• 2016

OpenCV(Open Computer Vision)에서 제공하는 얼굴 검출 알고리즘은 Haar-like feature와 Cascade 방식을 이용하여 얼굴의 패턴을 찾아내 얼굴을 검출한다. 그러나 우연히 얼굴이 아닌 곳이 얼굴과 유사한 패턴일 경우, 얼굴로 인식하는 오류를 범하게 된다. 따라서 본 논문은 MCT(Modified Census Transform)와 신경망을 이용하여 잘못된 얼굴 검출 영역을 감소시키는 알고리즘을 제안한다. MCT는 다양한 조명 조건에서도 강인한 얼굴 영상의 지역적 구조 특징을 추출하기 위하여 사용되고, 신경망 알고리즘은 Haar-Cascade 알고리즘의 얼굴 검출 방법으로 검출된 영역이 실제로 얼굴인지 아닌지를 판단하기 위하여 사용된다. 실험에서 사용된 6개의 데이터들은 인터넷에서 수집한 것으로서, Haar-Cascade 알고리즘의 얼굴 검출 방법으로 얼굴을 검출하였을 때 오검출된 영역이 1개 이상 존재한다. 본 논문에서 제안한 알고리즘으로 실험한 결과, Haar-Cascade 알고리즘의 얼굴 검출 방법에 비하여 오검출된 영역이 감소된 것을 확인할 수 있었다.

• Korean Chemical Engineering Research
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• 제58권3호
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• pp.430-437
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• 2020

본 연구에서는 다단제어(Cascade Control)를 위한 안티 와인드업(Anti-windup) 기술을 개발하였다. 다단제어는 외란을 보다 효과적으로 제어하기 위해 내부에 되먹임(Feedback) 제어루프를 추가한 제어구조이다. 단일루프제어(Single-loop Control)와는 다르게 두 개의 제어루프로 이루어져 내부의 종속제어루프(Secondary Control)가 외부의 주제어루프(Primary Control)에 영향을 미치는 특징을 가지고 있다. 산업현장에서 다단제어에 적용하는 기존의 안티 와인드업 기술은 주로 주제어기(Primary Controller)와 종속제어기(Secondary Controller)에 각각 로컬 역연산법(Back Calculation)을 적용하는 것이다. 하지만 이 방법은 종속제어기의 제어출력이 포화되었을 때 발생하는 주제어기의 적분누적(Integral-windup) 현상을 효과적으로 제거하지 못한다. 이를 해결하기 위해 기존 로컬 안티 와인드업 기술을 확대 적용한 두 가지의 다단제어용 안티 와인드업 기술을 제안한다. 첫 번째는 다단 조건부 적분법(Cascade Conditional Integration)이고 두 번째는 다단 역연산법(Cascade Back Calculation)으로 단일루프제어에 적용되어 왔던 로컬 조건부 적분법과 역연산법을 다단제어로 확대 적용하여 다단제어 시스템에서 PID제어기의 적분누적 현상을 방지하고자하였다. 개발한 다단 조건부 적분법과 다단 역연산법은 간단하고 직관적이면서도 종속제어기의 제어출력의 포화로 인해 발생한 적분누적현상을 효과적으로 방지할 수 있고 공정이나 제어기 형태에 상관없이 우수한 제어성능을 유지할 수 있었다. 향후 실제 공정 적용을 통해 신뢰성을 확보한다면 산업현장의 다단제어기 성능을 개선하는데 크게 기여를 할 수 있을 것이다.

• Journal of Mechanical Science and Technology
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• 제19권12호
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• pp.2303-2311
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• 2005

Super low temperature has many applications nowadays, from the chemical processing, automotives manufacturing, plastic recycling, etc. Considering of its wide application in the present and the future, study of the super-low temperature refrigeration system should be actively carried out. Super low state temperature can be achieved by using multi-stage refrigeration system. This paper present the development and testing of cascade refrigerator system for achieving super-low temperature. On this experiment, two different types of HCFCs refrigerants are utilized, R-22 and R-23 were applied for the high stage and the low-pressure stage respectively. The lowest temperature in the low-pressure evaporator that can be achieved by this cascade refrigeration system is down to $-85^{\circ}C$. This experiment is aimed to study the effect of inlet pressure of the low-pressure stage evaporator and low-pressure stage compressors inlet pressure characteristics to the overall temperature characteristics of cascade refrigeration system.