• 제목/요약/키워드: Carvacrol

검색결과 48건 처리시간 0.021초

식물성 오일을 깔짚에 처리시 pH, 병원균 및 휘발성 지방산에 미치는 영향에 대한 연구 (Effects of Essential Oils on pH, Pathogen, and Volatile Fatty Acid Content in Poultry Litter)

  • 장우환;최인학
    • 한국환경과학회지
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    • 제32권2호
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    • pp.139-143
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    • 2023
  • The effects of essential oils on pH, pathogens, and volatile fatty acids (VFA) in two poultry litters were investigated through a lab study. Essential oil-added poultry litters were randomly divided to two groups: control (200 g poultry litter) and Treatment (50 g thymol/Briefly, 200 g broiler litter was treated with or without 50 g thymol (Control and T1, respectively; 1 groups) and 200 g duck litter was treated with or without 50 g carvacrol (Control and T2, respectively; 2 group). Adding thymol to broiler litter increased the pH, reduced pathogens, and did not affect VFA. Interestingly, adding carvacrol slightly reduced the pH of duck litter, but had no significant effect on reducing pathogens and VFA. This difference is probably because the essential oil used and the properties of the two litters are different. In addition, pH was thought to control the odor generated from the litter, but this has not been proven. Further field studies should focus on clarifying this point.

Thymol과 Carvacrol 유도체들의 합성과 식물병원균에 대한 항균활성 (In vitro and in vivo antifunal activaties of derivatives of thymol( I ) and carvacrol(II) againt phytopathogenic fungi)

  • 최원식;정찬진;장도연;차경민;엄대용;김태준;정봉진
    • 농약과학회지
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    • 제10권4호
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    • pp.237-248
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    • 2006
  • 항균활성을 나타내는 thyme oil의 주성분인 thymol(I)과 carvacrol(II)을 출발물질로 하여 ester, sulfonyl ester, carbamate, ether와 phosphoyl ester 계열 유도체 41종을 합성하였다. IR, GC/MS 와 $^1H$-NMR spectrum을 이용하여 합성된 화합물들을 확인하였다. 이들 유도체들을 10종의 식물 병원균에 대하여 항균활성 실험을 실시한 결과 몇가지 화합물이 우수한 항균활성을 나타내었다. 이들 화합물에 대한 in vivo실험은 오이, 토마토와 벼 작물에서 실시하였다. 그 결과, 2-isopropyl-5-methylphenyl acetate(I-1a)가 오이 잿빛곰팡이 병균(Botrytis cinerea)과 벼도열병균(Pyrcularia oryzae)에 높은 항균활성을 나타내었으며, methyl(2-isopropyl-5-methylphenoxy)acetate(I-6d)는 벼 잎집무늬마름병균(Rhizoctonia solani)에서 ethyl4-(2-methyl5-isopropylphenoxy)-crotonate(I-7d)는 토마토역병균(Phytophthora infestans)에서 우수한 항균활성을 나타내었다.

세이보리(S. hortensis)의 정유성분과 대사체 분석에 대하여 (Essential Oil Ingredient and Metabolites Analyses in Savory (Satureja hortensis))

  • 신경순;조태동
    • 한국환경과학회지
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    • 제31권3호
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    • pp.255-263
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    • 2022
  • The relationship between environmental growth conditions of savory(Satureja hortensis) and Zn and vitamin B3 has been previously reported. Based on these results, HPLC and GC-MS were used to investigate the levels of phenolic compounds and perform metabolite analysis, respectively, in plants collected from different areas. Differences were observed in the levels of polyphenols and flavonoids depending on sampled areas and natural conditions. Next, HPLC and metabolite analyses confirmed the presence of bioactive substances. The results also showed that the longer the storage time, the higher was the content of carvacrol and of rosmarinic acid. Finally, the difference in the active ingredients was minimal when plants were cultivated under growth conditions similar to those in the place of origin.

국내 자생 백리향의 추출용매에 따른 페놀함량 (Phenol Contents of Solvent Extraction in Several Domestic Thymus Quinquecostatus Celak)

  • 백정애;백이화;장매희
    • 생물환경조절학회지
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    • 제18권4호
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    • pp.468-474
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    • 2009
  • 지역별 백리향 지상부 잎의 phenols 성분의 효과적인 추출을 알아보기 위해 추출용매를 달리하여 추출하고, GC-MS로 분석한 결과thymol과 carvacrol을 포함한 phenol함량이 methanol 추출 시 울릉도, 제주 중간산지, 경기도, 제주도 고산지, 강원도 종이 각각 92.21, 84.92, 77.43, 74.16, 73.51%로 추출되었으며, ethanol 추출 시 전체 추출 성분 중 강원도, 제주도 중간산종, 경기도, 울릉도, 제주고산종이 각각 93.64, 93.62, 90.74, 89.52, 72.65% 순으로 나타났다. Hexane을 용매로 추출하였을 때에는 강원도와 울릉도 서식의 백리향은 거의 100, 95.71%의 phenol만 추출되었다.

Carvacrol improves blood lipid and glucose in rats with type 2 diabetes mellitus by regulating short-chain fatty acids and the GPR41/43 pathway

  • Yan Sun;Hai Qu;Xiaohong Niu;Ting Li;Lijuan Wang;Hairui Peng
    • The Korean Journal of Physiology and Pharmacology
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    • 제28권1호
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    • pp.1-10
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    • 2024
  • Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia and dyslipidemia. Carvacrol (CAR) has demonstrated the potential to mitigate dyslipidemia. This study aims to investigate whether CAR can modulate blood glucose and lipid levels in a T2DM rat model by regulating short-chain fatty acids (SCFAs) and the GPR41/43 pathway. The T2DM rat model was induced by a high-fat diet combined with low-dose streptozocin injection and treated with oral CAR and/or mixed antibiotics. Fasting blood glucose, oral glucose tolerance, and insulin tolerance tests were assessed. Serum lipid parameters, hepatic and renal function indicators, tissue morphology, and SCFAs were measured. In vitro, high glucose (HG)-induced IEC-6 cells were treated with CAR, and optimal CAR concentration was determined. HG-induced IEC-6 cells were treated with SCFAs or/and GPR41/43 agonists. CAR significantly reduced blood lipid and glucose levels, improved tissue damage, and increased SCFA levels in feces and GPR41/43 expression in colonic tissues of T2DM rats. CAR also attenuated HG-induced apoptosis of IEC-6 cells and enhanced GPR41/43 expression. Overall, these findings suggest that CAR alleviates blood lipid and glucose abnormalities in T2DM rats by modulating SCFAs and the GPR41/43 pathway.

열탁착식 가스크로마토질량분석기에 의한 국내 산지별 백리향의 휘발성향기성분 (Volatile Aroma Compounds of Several Domestic Thymus quinquecostatus by Thermal Desorption Gas Chromatograph Mass Spectrometer)

  • 장매희;이광우;백정애
    • 생물환경조절학회지
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    • 제20권1호
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    • pp.14-20
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    • 2011
  • 지역별로 자생하고 있는 백리향 지상부의 휘발성 향기 성분 및 방부성 물질인 phenols의 성분을 조사하기 위해 제주도 고산종, 제주도 중간산종, 경기도, 울릉도, 강원도 서식종을 TD-GC-MSD로 분석한 결과 제주도 중간산종에서 상대적으로 높은 62종의 물질이 조사되었으며 함량도 $7365.22{\mu}g/m^3$으로 높은 농도를 나타냈다. 또한 백리향의 휘발성 향기성분 중 제주도 중간산종이 다른 조사지역보다 상대적으로 thymol과 carvacrol의 phenol성 물질이 다른 휘발성분에 비해 35.92%로 높은 결과를 보였다.

Optimization of Algerian Thymus fontanesii Boiss. & Reut Essential Oil Extraction by Electromagnetic Induction Heating

  • Ali, Lamia Sid;Brada, Moussa;Fauconnier, Marie-Laure;Kenne, Tierry
    • Natural Product Sciences
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    • 제24권1호
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    • pp.71-78
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    • 2018
  • The present study deals with the determination of optimal values of operating parameters such as the temperature of heating, the mass of the plant material and the volume of water leading to the best yield of electromagnetic induction (EMI) heating extraction of Algerian Thymus fontanesii essential oil. After an appropriate choice of the three critical variables, eight experiments leaded to a mathematical model as a first-degree polynomial presenting the response function (yield) in the relation to the operating parameters. From the retained model, we were able to calculate the average response, the different effects and their interactions. The maximum of essential oil recovery percentage relative to the initial mass of plant material was 1.69%, and was obtained at ($140^{\circ}C$, 250 g and 4.5 L). The chemical composition of the Algerian T. fontanesii essential oil under the obtained optimal conditions ($140^{\circ}C$, 250 g and 4.5 L), determined by GC/MS and GC/FID, reveled of the presence of major components such as: carvacrol ($70.6{\pm}0.1%$), followed by p-cymene ($8.2{\pm}0.2%$).

Addition of Capsicum oleoresin, Carvacrol, Cinnamaldehyde and their mixtures to the broiler diet II: Effects on meat quality

  • Ipcak, Hasan Huseyin;Alcicek, Ahmet
    • Journal of Animal Science and Technology
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    • 제60권4호
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    • pp.9.1-9.11
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    • 2018
  • Background: In recent years, with the prohibition of antibiotics used as growth stimulants in the nutrition of farm animals, researchers have searched for alternative natural and reliable products in order to be able to sustain the developments experienced during the use of antibiotics and to overcome the possible inconveniences. In this context, studies on evaluation of essential oils in poultry nutrition have been reported to improve the utilization of feed, stimulate the release of digestive enzymes, increase absorption in the stomach and intestines, antimicrobial and anti-parasitic effects and thus, can be an alternative to antibiotics and improve meat quality as well. Indeed, this study has been carried out to explore the effects of the addition of 150 mg/kg capsicum oleoresin (CAP), carvacrol (CAR), cinnamaldehyde (CIN) or their mixture (CAP+CAR+CIN) into the broilers' ration over sensory, physical and chemical properties in breast meat and leg meat. Methods: Experiments were conducted over 400 male and female broiler chicks (Ross-308) in 5 groups (1 control group and 4 treatment groups), each composed of 80 chicks. The control group was fed without feed additives while the second, third, fourth and the fifth groups were fed with 150 mg CAP/kg feed, 150 mg CAR/kg feed, 150 mg CIN/kg feed, and 150 mg CAP+CAR+CIN/kg feed, respectively. Results: Addition of CAP, CAR, CIN or CAP+CAR+CIN had effects on the sensory (of taste, tenderness, juiciness and overall acceptability); physical properties (of $L^*$ value and toughness), the chemical properties (of DM, CF, CP, linoleic, EPA, behenic, MUFA, PUFA and ${\Sigma}n-6$ of the leg meat), the physical characteristics (of toughness and firmness), and the chemical properties (of CF, CP, linoleic, ecosenic, EPA, lignoseric, MUFA and ${\Sigma}n-3$) of the breast meat in comparison to control group. Furthermore, while the treatments had positive impacts on thawing loss, cooking loss and water holding capacity in both breast and leg meat; no effect was observed on pH value and lipid oxidation on day 1, day 4 and day 8. Conclusion: The results strongly suggested that the addition of CAP, CAR, CIN or CAP+CAR+CIN to the rations of the broiler chicks changed the sensory, physical and chemical properties of breast and leg meat. It was also observed that these compounds were more effective when they were added to the ratio as a mixture rather than adding them individually.

피마자유와 양명아주 추출물을 원료로 하는 유기농업자재 유효성분의 열 안정성 평가 (Thermal Stability of Representative Bioactive Compounds in Biopesticide Derived from Castor Oil or Wormseed Extract under Controlled Temperature)

  • 최근형;정동규;진초롱;노진호;박병준;문병철;김진효
    • 한국환경농학회지
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    • 제36권1호
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    • pp.17-21
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    • 2017
  • BACKGROUND: Castor oil and wormseed extract are important active ingredients for biopesticide, and ricinoleic acid in castor oil and three monoterpenes (ascaridole, carvacrol and p-cymene) in wormseed extract are known bioactive substances. However, their stabilities had not been studied, even though the stability was the core property for estimation of shelf-life of biopesticide. Aimed to investigate the thermal stabilities of the bioactive substances in castor oil and wormseed extracts. METHODS AND RESULTS: The contents of ricinoleic acid and three monoterpenes (ascaridole, carvacrol and p-cymene) were analyzed by gas chromatography (GC). The thermal stabilities of the bioactive substance were measured at $0^{\circ}C$, $23^{\circ}C$, $30^{\circ}C$, $40^{\circ}C$, $45^{\circ}C$ and $54^{\circ}C$ for 84 d. The half-lives of ricinoleic acid in biopesticides was ranged from 28.9 d to 57.8 d at $30^{\circ}C$, and the stability of pure castor oil were located in the range ($t_{1/2}$=46.2d for Indian product and 27.7 d for Korean product) at the same temperature. The half-lives of the total monoterpenes in biopesticides were ranged from 3.9 d to 27.7 d at $30^{\circ}C$. Among the monoterpenes, the stability ascaridole and p-cymene were decreased in acidic condition. All the bioactive substances showed similar stability on the different thermal conditions. CONCLUSION:The half-lives of most bioactive substance from castor oil and wormseed extracts were less than 100 d. To increase the stability of bioactive substance in biopesticide, stabilizing additives like antioxidant and oxygen remover should be considered to extend of the shelf-life.