• Title/Summary/Keyword: Cardiovascular system

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Compensation of Skin Surface Temperature Variation on the PPG for the U-Healthcare System (U-Healthcare시스템을 위한 PPG의 피부표면의 온도변화보상)

  • Yeom, Ho-Jun
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.11 no.6
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    • pp.319-324
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    • 2011
  • This study aims to investigate statistical variations and relationships of blood pressure (BP), phtotplethysmography (PPG) and cardiovascular parameters on changes in local skin surface temperature (SST) during gradual cooling and heating. Results showed that local SST changes affected the Finometer BP, the PPG waveforms and total peripheral resistance, but not oscillometric BP, heart rate, stroke volume and cardiac output. Therefore, in order to reduce for the errors, temperatures should be controlled or compensated when components of the PPG waveform are used to evaluate cardiovascular status in temperature variation environments.

Acute Heart Failure after Relief of Massive Pericardial Effusion (대량의 심낭삼출액 제거 후 발생한 급성 심부전)

  • Jung Tae-Eun;Lee Dong-Hyup
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.702-705
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    • 2006
  • Severe left ventricular dysfunction after relief of massive pericardial effusion has been rarely reported. Interventricular volume mismatch, acute distention of the cardiac chambers and interplay of autonomic none system are believed to be the possible causes for ventricular dysfunction. Presenting two patients who had marked decrease in global ventricular systolic function after relief of pericardial tamponade by subxyphoid pericardial window, we recommend gradual removal of pericardial fluid under hemodynamic monitoring, especially in patient with postcardiotomy tamponade.

PHACE association with intracranial, oropharyngeal hemangiomas, and an atypical patent ductus arteriosus arising from the tortuous left subclavian artery in a premature infant

  • Kim, Do-Hyun;Choi, Jang-Hwan;Lee, Jung-Ha;Kim, Hee-Sup
    • Clinical and Experimental Pediatrics
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    • v.55 no.1
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    • pp.29-33
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    • 2012
  • PHACE association is a rare neurocutaneous condition in which facial hemangiomas associate with a spectrum of posterior fossa malformations, arterial cerebrovascular anomalies, cardiovascular anomalies, and eye anomalies. We reported a case of PHACE association in a premature infant showing facial, intracranial, and oropharyngeal hemangiomas with evidence of the Dandy-Walker variant and complicated cardiovascular anomalies, including a right-sided aortic arch and an atypical patent ductus arteriosus arising from a tortuous left subclavian artery. To our knowledge, intracranial hemangiomas are rare in PHACE association, and a concomitant oropharyngeal hemangioma has not been previously reported in the PHACE association literature. In infants presenting with large, plaque-like facial hemangiomas, it is important to conduct active cardiovascular and neurological evaluations. Special attention should be given to the laryngoscopic examination to search for additional hemangiomas in the airway.

$DaVinci^{TM}$ S robot-assisted esophagectomy in a 83-year-old patient with esophageal cancer (고령의 식도암 환자에서 다빈치 S 로봇을 이용한 식도 절제술)

  • Haam, Seok-Jin;Park, Seong-Yong;Paik, Hyo-Chae
    • Korean Journal of Bronchoesophagology
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    • v.14 no.2
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    • pp.53-56
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    • 2008
  • The postoperative respiratory complications such as pneumonia and ARDS, are poor prognostic factors after esophagectomy in patients with esophageal cancer. To avoid these complications, there have been attempts to use minimally invasive approach. Recently introduced daVinciTM S surgical system is used in esophagectomy because of its advantages of minimal invasiveness, clear 3-dimensional imaging and precise handling of robotic arms. We report a 83-year-old esophageal cancer patient who underwent daVinciTMS robot-assisted esophagectomy, laparoscopic stomach mobilization followed by cervical esophagogastrostomy.

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Design and Evaluation of Cardiovascular Impedance Simulator Considering Mechanical Limits (기계적 한계를 고려한 심혈관 순환계 임피던스 시뮬레이터 설계 및 평가)

  • Gwak, Kwan-Woong
    • Journal of the Korean Society for Precision Engineering
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    • v.25 no.1
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    • pp.151-159
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    • 2008
  • The parameter-based cardiovascular impedance simulator that is able to overcome the limits of conventional mock circulatory systems is critical for the development and test of biomedical devices including artificial heart. The concept of impedance simulator was validated mathematically in a previous study using high-gain feedback linearization control which, however, may cause serious difficulties and limits for practical implementation. In this study, therefore, practical applicability of the impedance simulator is investigated considering the physical limits such as motor speed and torque. Simple PID controller which do not require complex model of the simulator is used considering the practical implementation. Design guidelines of the impedance simulator are also provided based on the results.

Long-term measurement of physiological cardiovascular parameters using telemetry system in dosgs.

  • Kim, Eun-Joo;Seo, Joung-Wook;Choi, Gyu-Kap;Park, Eun-Kyung;Kim, Ki-Suk;Shin, Won-Ho;Han, Sang-Seop
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.87.1-87.1
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    • 2003
  • With the issuance of the ICH “Guidance for industry S7A Safety Pharmacology Studies For Human Pharmaceuticals” in July 2001 came the preference for the use of unanesthetized animals when evaluation the safety profile of new pharmaceutical agents. Telemetry provides a means of obtaining measurements of physiological functions in conscious animals without the problems associated with classical cardiovascular measuring methods. The Korea Institute of Toxicology (KIT) established the telemetric measurement of cardiovascular parameters, such as Blood pressure, Heart rate, ECG (PR, RR, QRS, QT and QTcB interval) under GLP conditions. (omitted)

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The influence of extremely low frequency magnetic field on cardiovascular response

  • Kim, Jeong-Soo;Jeong, Ji-Hoon;Sung, Ji-Hyun;Bae, Ki-Lyong;Kum, Chan;Kang, Hee-Yun;Sohn, Uy-Dong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.274.1-274.1
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    • 2002
  • There have been some reports showing that cardiovascular response is affected by exposure to extremely low frequency magnetic field (ELF-MF). In this experiment. we intended to observe if ELF-MF affects the basal level of cardiovascular response and effect of drugs acting on sympathetic nervous system. Rats exposed to MF (60 Hz. 20 G) for 1 or 5 days and sham were anesthetized with pentobarbital-Na. Carotid artery and jugular vein were intubated to measure blood pressure (BP) and inject drug respectively. (omitted)

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A Tale of Two Models: Mouse and Zebrafish as Complementary Models for Lymphatic Studies

  • Kim, Jun-Dae;Jin, Suk-Won
    • Molecules and Cells
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    • v.37 no.7
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    • pp.503-510
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    • 2014
  • Lymphatic vessels provide essential roles in maintaining fluid homeostasis and lipid absorption. Dysfunctions of the lymphatic vessels lead to debilitating pathological conditions, collectively known as lymphedema. In addition, lymphatic vessels are a critical moderator for the onset and progression of diverse human diseases including metastatic cancer and obesity. Despite their clinical importance, there is no currently effective pharmacological therapy to regulate functions of lymphatic vessels. Recent efforts to manipulate the Vascular Endothelial Growth Factor-C (VEGFC) pathway, which is arguably the most important signaling pathway regulating lymphatic endothelial cells, to alleviate lymphedema yielded largely mixed results, necessitating identification of new targetable signaling pathways for therapeutic intervention for lymphedema. Zebrafish, a relatively new model system to investigate lymphatic biology, appears to be an ideal model to identify novel therapeutic targets for lymphatic biology. In this review, we will provide an overview of our current understanding of the lymphatic vessels in vertebrates, and discuss zebrafish as a promising in vivo model to study lymphatic vessels.

Potentials of Chenpi on Metabolic Syndrome: A Review

  • Lee, Yoo-na;An, Yu-min;Kim, Jun-seok;Baek, Kyungmin
    • The Journal of Internal Korean Medicine
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    • v.42 no.4
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    • pp.645-671
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    • 2021
  • Objectives: Metabolic Syndrome (MetS) is strongly related with central obesity, hypertriglyceridemia, low high-density lipoprotein-cholesterol (HDL-C), hyperglycemia, and hypertension. This study reviewed the potential of Chenpi in treatment of MetS through amelioration of co-related diseases, such as diabetes mellitus, hyperlipidemia, obesity, hepatic steatosis, and inflammation. Methods: Six electronic databases (Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Traditional Knowledge Portal, Korea Institute of Oriental Medicine (KIOM), Research Information Sharing Service (RISS), PubMed, and Embase) were used to search for in vitro, in vivo, and clinical research that discusses the potential effects of Chenpi (Citrus unshiu Markovich, Citrus reticulata Blanco) on diabetes mellitus, hyperlipidemia, obesity, hepatic steatosis, and inflammation. Results: This review suggests the potential of Chenpi as a candidate for the treatment of metabolic syndrome through improvement of co-related diabetes, hyperlipidemia, obesity, hepatic steatosis, and inflammation. However, comparison of the results of each study was limited by a lack of quantification of the experimental materials.

Influencing Factors of the Metabolic Index and Cardiovascular Risk Factors on Depressive and Non-depressive Groups in the Vulnerable Diabetic Elderly Women (취약계층 당뇨병 여성노인의 대사증후군지표와 심혈관 위험정도가 우울증상 여부에 미치는 요인)

  • Sung, Kiwol
    • Journal of Korean Biological Nursing Science
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    • v.21 no.2
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    • pp.123-132
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    • 2019
  • Purpose: The purpose of this study was to identify influencing factors of metabolic index and cardiovascular risk factors, on depressive and non-depressive groups, in vulnerable diabetic elderly women. Methods: Participants were 137 vulnerable diabetic elderly women, using health centers in D city. Data were collected through interviews September though December 2017. The metabolic index was measured using National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATP III), and cardiovascular risk factors were measured using Framingham Risk Score (FRS). Depressive and non-depressive groups were divided by the score of Geriartric Depress Scale Short Korea Version (GDSSF). Collected data were analyzed using a x2 test, independent t-test, and binary logistic regression, with the SPSS/WIN 25.0 program. Results: Vulnerable diabetic elderly women, did not exercise in the depressive groups, and had higher triglyceride (TG), total cholesterol (TC) and larger waists, than in the non-depressive group. Results show that lack of exercise (OR= 6.30), is the highest risk factor, influencing the depressive symptom in vulnerable diabetic elderly women. Conclusion: These results suggest that to reduce depressive symptom levels among vulnerable diabetic elderly women, nursing interventions are needed to increase exercise and decrease TG, TC, and waist size, particularly in improving exercise of vulnerable diabetic elderly women.