• Title/Summary/Keyword: Cardiovascular circulation

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Studies of Serum and Urine Potassium Changes During, and after Extracorporeal Circulation in open heart Surgery (체외순환 전후 혈중및 소변에서의 potassium 변화에 관한 관찰)

  • Kim, Yun;Cho, Bum-Koo;Hong, Seung-Nok
    • Journal of Chest Surgery
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    • v.11 no.3
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    • pp.296-302
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    • 1978
  • This experiment was carried out to study the change of potassium before, during, and after extracorporeal circulation. Serum potassium and urinary potassium excretion were examined in 7 cases of patient who were taken open heart surgery using extracorporeal circulation. All of 7 cases were administered 10-25mEq of KC1 during extracorporeal circulation. Serum potassium was not changed significantly during, and after operation, but urinary potassium excretion was declined during extracorporeal circulation and tend to rise after extracorporeal circulation. This result showed no remarkable relation of serum potassium and urinary potassium excretion.

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A Multi-scale Simulation Model of Circulation Combining Cardiovascular Hemodynamics with Cardiac Cell Mechanism (심근세포-심혈관계 혈류역학이 결합된 복합적 순환계 모델에 관한 연구)

  • Ko Hyung Jong;Leem Chae Hun;Shim Eun Bo
    • Journal of Institute of Control, Robotics and Systems
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    • v.10 no.12
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    • pp.1164-1171
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    • 2004
  • A new multi-scale simulation model is proposed to analyze heart mechanics. Electrophysiology of a cardiac cell is numerically approximated using the previous model of human ventricular myocyte. The ion transports across cell membrane initiated by action potential induce an excitation-contraction mechanism in the cell via cross bridge dynamics. Negroni and Lascano model (NL model) is employed to calculate the tension of cross bridge which is closely related to the ion dynamics in cytoplasm. To convert the tension on cell level into contraction force of cardiac muscle, we introduce a simple geometric model of ventricle with a thin-walled hemispheric shape. It is assumed that cardiac tissue is composed of a set of cardiac myocytes and its orientation on the hemispheric surface of ventricle remains constant everywhere in the domain. Application of Laplace law to the ventricle model enables us to determine the ventricular pressure that induces blood circulation in a body. A lumped parameter model with 7 compartments is utilized to describe the systemic circulation interacting with the cardiac cell mechanism via NL model and Laplace law. Numerical simulation shows that the ion transports in cell level eventually generate blood hemodynamics on system level via cross bridge dynamics and Laplace law. Computational results using the present multi-scale model are well compared with the existing ones. Especially it is shown that the typical characteristics of heart mechanics, such as pressure volume relation, stroke volume and ejection fraction, can be generated by the present multi-scale cardiovascular model, covering from cardiac cells to circulation system.

Extraction of an Infected Permanent Pacemaker Lead Using Cardiopulmonary Bypass - 2 case reports - (체외 순환을 이용한 감염된 영구 심박동기 도선의 제거 - 2예 보고 -)

  • Oh, Tak-Hyuck;Kim, Gun-Jik;Lee, Jong-Tae
    • Journal of Chest Surgery
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    • v.43 no.1
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    • pp.86-88
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    • 2010
  • Implanting a pacemaker is the most often used intervention for treating bradycardia. The most commonly used pacemaker is the intracardiac pacemaker, yet it can have many complications. An infected pacemaker can spread to systemic infection and the condition of the patient can quickly get worse, so if an infected pacemaker is suspected, then the pacemaker must be removed. Apart from the use of interventional methods such as a loop or a weight, we can take a more aggressive approach by using extracorporeal circulation for removal of the pacemaker. We report here on two cases in which extracorporeal circulation was used to remove the infected pacemakers.