• Smart Media Journal
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• v.7 no.4
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• pp.90-98
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• 2018

A Multilinear LDA Method of Tensor Representation for ECG Signal Based Individual Identification Electrocardiogram signals, included in the cardiac electrical activity, are often analyzed and used for various purposes such as heart rate measurement, heartbeat rhythm test, heart abnormality diagnosis, emotion recognition and biometrics. The objective of this paper is to perform individual identification operation based on Multilinear Linear Discriminant Analysis (MLDA) with the tensor feature. The MLDA can solve dimensional aspects of classification problems in high-dimensional tensor, and correlated subspaces can be used to distinguish between different classes. In order to evaluate the performance, we used MPhysionet's MIT-BIH database. The experimental results on this database showed that the individual identification by MLDA outperformed that by PCA and LDA.

• Healthcare Informatics Research
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• v.24 no.4
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• pp.276-282
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• 2018

Objectives: Due to the uncontrolled increase of the mobile health applications and their scarce use by elderly for reason of absence credibility of measurements by lack scientific support, the aim of this study was to evaluate the differences between the biophysical measurements based on standard instrument against a mobile application using controlled experiments with elderly to propose an effective validation model of the developed apps. Methods: The subjects of the study (50 people) were elderly people who wanted to check their weight and cardiac status. For this purpose, two mobile applications were used to measure energy expenditure based on physical activity (Activ) and heart rate (SMCa) during controlled walking at specific speeds. Minute-by-minute measurements were recorded to evaluate the average error and the accuracy of the data acquired through confidence intervals by means of statistical analysis of the data. Results: The experimental results obtained by the Activ/SMCa apps showed a consistent statistical similarity with those obtained by specialized equipment with confidence intervals of 95%. All the subjects were advised and trained on the use of the applications, and the initial registration of data to characterize them served to significantly affect the perceived ease of use. Conclusions: This is the first model to validate a health-app with elderly people allowed to demonstrate the anthropometric and body movement differences of subjects with equal body mass index (BMI) but younger. Future studies should consider not only BMI data but also other variables, such as age and usability perception factors.

• The Korean Journal of Emergency Medical Services
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• v.25 no.3
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• pp.179-188
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• 2021

Purpose: This study aimed to identify effective cardiopulmonary resuscitation methods by comparing the fatigue of rescuers according to various positions in cardiopulmonary resuscitation situations conducted on beds in hospitals. Methods: An experimental study of students in the department of emergency medical service in H University, G Metropolitan City was conducted in four positions for applying chest pressure on mannequins on beds. Results: As a result of measuring the muscle fatigue of four muscle attachments according to the four positions conducted on the bed, the average was 3.4%, the P was significant at 0.001, and the fatigue difference was confirmed to occur depending on the attachment. An analysis of pressure depth by pose revealed that P1, P2, P3, and P4 have a depth of 58.3, 55.1, 56.4, and 56.3 mm, respectively, with P4 having the deepest depth. Conclusion: Among the various postures of the rescuer during cardiopulmonary resuscitation performed on the bed in the hospital, P1 is thought to be the most tiring, although its associated CPR quality is good.

• Journal of The Korea Institute of Healthcare Architecture
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• v.30 no.2
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• pp.23-34
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• 2024

Purpose: The Hybrid care environment, combining interventional procedures and surgeries in one space, is crucial for managing complex diseases, responding to emergencies, and reducing recovery times and pain. This study provides foundational data for creating architectural guidelines for a Hybrid Operating Unit in a general hospital's surgical department, focusing on cardiovascular care. Methods: The study analyzed the spatial and configuration types of the Vascular Angiography Unit and the Cardiac Operating Unit, which are the basic components of the Hybrid Operating Unit, through a literature review. Based on the initial research findings, interviews with experts were conducted. Results: In the Hybrid Operating Process, the study proposed spatial configuration alternatives that consider the positioning of medical staff and the types and arrangement changes of equipment, including Angiography, Heart-lung machines, and other surgical tools and instruments. Implications: The integration of the two units leads to increased diversity and demand for medical staff, equipment, and supplies during surgical and interventional procedures. Therefore, strategic spatial configurations and equipment placement are necessary to effectively respond to these needs.

• The Korean Journal of Nuclear Medicine
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• v.14 no.2
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• pp.19-27
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• 1980

Although primary application of radioisotope scanning technics to the liver has been of use in the detection of the intra-hepatic space occupying lesion from the normal functioning liver parenchyme, there has been on increasing awareness of its use in evalution of Liver function. In this study, the diseases of the liver were classified into group A,B,C and D by the liver scanning findings, conventional liver function tests and clinical findings. Following were the results: 1. The colloidal radiogold liver scan appeared normal in the group A, also the albumin in serum, alkaline phosphatase activity and prothrombin time were within normal levels in this group. 2. In the group B, there were acute hepatitis 24(48%), chronic hepatitis 5(10%), toxic hepatitis 3(6%), subacute hepatic necrosis 3(6%), typhoid liver 4(8%), hepatic tuberculosis 2(4%), diabetes mellitus 3(6%) and others 3(6%). In this group, SGOT and SGPT were increased predominantly as compared with group A, and the liver scan showed small amount of mottling of activity and faintly visualized spleen. 3. In the group C, there were postnecrotic liver cirrhosis 30(60%), Laennec cirrhosis 10(20%), cardiac cirrhosis 1(2%), cholangiocarcinoma 1(2%), chronic active hepatitis 6(12%), hepatic milliary tuberculosis 1(2%) and gall bladder cancer 1(2%). In this group, the albumin in serum and prothrombin time were lowered significantly and the liver scan showed severe mottling of activity with extra-hepatic uptake in the spleen and bone marrow along the vertebral column. 4. In the group D, there were primary hepatoma 26(52%), hepatoma with liver cirrhosis 7(14%), metastatic liver cancer 5(10%), liver abscess 10(20%), multiple liver cyst 1(2%) and cystic duct adenoma 1(2%), In this group, the alkaline phosphatase activity was elevated with single or multiple intrahepatic space occupying lesion in the radiogold colloid liver scan.

• The Journal of Internal Korean Medicine
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• v.32 no.3
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• pp.345-360
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• 2011

Objectives : This study was examined to investigate the effects of Cheonmagudeng-um gagam (CGG) extract on spontaneous hypertension. Methods : For the study of CGG, we divided rats into three groups. The normal group was Wister Kyoto rats (WKY). The control group was spontaneously hypertensive rats (SHR). The treatment group was SHR which were administered CGG extract (SHR-CGG). SHR-CGG were orally administered CGG extract that was diluted in distilled water at the various concentrations for 4 weeks (234.5 mg/kg) and SHR were orally administered the same dosage of plain distilled water as SHR-CGG. Then we measured anti-oxygen effects, ACE inhibitory activity, weight of heart and kidney, blood pressure, heart rate, plasma aldosterone, electrolyte, creatinine, uric acid, BUN, and observed the cortex of the cardiac muscle, kidney, and adrenal gland. Results : CGG increased DPPH scavenging activity and SOD similar activity depending on the concentration. CGG significantly decreased ROS, TNF-${\alpha}$, IL-6, IL-$1{\beta}$, heart weight, blood pressure, heart rate, aldosterone, and BUN in SHR. CGG increased ACE inhibition activity depending on the concentration. CGG inhibited the heart, kidney and adrenal gland tissue injury that is caused by hypertension. Conclusions : These results suggest that CGG is effective in treatment and prevention of hypertension.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.10
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• pp.506-514
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• 2018

This study was conducted to investigate the relationship between hand grip strength and cardiopulmonary fitness in patients with myocardial infarction. In this retrospective study, 67 patients who experienced myocardial infarction for 10 months were analyzed. Hand grip strength was measured using a handheld dynamometer. Dynapenia was diagnosed based on a dominant hand grip strength of less than 30 kg for males and 20 kg for females. A cardiopulmonary exercise test was performed using a treadmill. Physical activity status was also evaluated. Cardiorespiratory fitness parameters were analyzed using a t-test and a Mann-Whitney test. VO2max, METmax, and exercise time significantly decreased in the dynapenia group compared with the non-dynapenia group. Correlation analysis revealed that dominant handgrip strength was significantly related to cardiorespiratory fitness parameters. Moreover, VO2max, METmax, and exercise time were significantly increased in patients with vigorous activity compared with the sedentary group. These findings indicate that handgrip strength could potentially be used as a marker of cardiorespiratory functions. Accordingly, patients with myocardial infarction should be evaluated for grip strength and physical activity, and we can encourage patients to participate actively in cardiac rehabilitation.

• Journal of Life Science
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• v.17 no.8 s.88
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• pp.1075-1081
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• 2007

We investigated whether 1) capsaicin ingestion (100 mg) enhances autonomic nervous system (ANS) activities associated with thermogenic sympathetic activity as energy metabolic modulator, 2) UCP1 and ${\beta}_{3}$-AR variants of each subjects influence with ANS activity. Eight healthy males (24.7 ${\pm}$ 1.8 yr) volunteered for this study. The cardiac autonomic nervous activities evaluated by means of heart rate variability of power spectral analysis and energy metabolism were continuously measured during 5-min rest for total 90-min resting condition with placebo or capsaicin oral administration chosen at random. The results indicated that there were no significant differences in heart rate during rest between both trials. Autonomic nervous activity increased in capsaicin tablet trial, but the difference did not reach the statistical significance. Capsaicin, however, induced significantly lower respiratory gas exchange ratio at Test3 (CAP: 0.80 ${\pm}$ 0.02 vs. 0.85 ${\pm}$ 0.02), means ${\pm}$ SE, p<0.05). In conclusion, it may be suggested the capsaicin consumption as a valuable supplement for the treatment of individual with hyperlipidemia and/or obesity by improving lipolysis. Further studies will also be considered genetic variants such as UCP1 and/or ${\beta}_{3}$-AR associated with obesity.

• Korean Journal of Plant Resources
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• v.24 no.1
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• pp.40-47
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• 2011

Sphagnum palustre is a semi aquatic moss. S. palustre has been used as Korean traditional medicine to treat cardiac pain and stroke. This study was carried out to analyze phytochemical constituents of S. palustre and investigate the biological activity for the promotion of human health. At first, we isolated seven compounds from the ethanolic extract of this plant, and their structures were characterized by spectroscopic methods. Their structures were characterized to be Coumarin(1), Caffeic acid(2), Quercetin(3), Astragalin(4), Luteolin(5), Chlorogenic acid(6), Rutin(7) were for the first time reported from this source. The ethanol extract from S. palustre which was tested for its anticancer activity against three human tumor cell line by in vitro assay.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.4
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• pp.480-486
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• 2012

To evaluate of biological activity of Chambirum ($Amaranthus$ $lividus$) $in$ $vitro$ and $in$ $vivo$, we investigated the free radical scavenging activity of its extracts $in$ $vitro$ and the effect of lyophilized powder on the serum lipid profile of rats fed cholesterol. ABTS, DPPH, and NO radical scavenging activities were tested from water and 80% ethanol extracts of Chambirum, and biological activities of the ethanol extracts were significantly higher than the water extracts. The total lipid and total cholesterol content of serum, atherogenic index (AI), and cardiac risk factor (CRF) were decreased significantly for the groups fed with a 5% and 10% supplement of Chambirum powder (HCA1 and HCA2) in comparison with the group fed cholesterol (HC). Triglyceride content decreased drastically in the HCA2 group, while its content was not decreased in the other group. HDL-cholesterol content was elevated in the HCA1 and HCA2 groups, but was not significantly different to the supplemented amount of Chambirum powder. GPT and ${\gamma}$-GTP activities were decreased significantly in the groups fed with Chambirum powder compared to the HC group. And the content of the lipid peroxide level was the same trend. Therefore, these results give evidence that Chambirum might be useful in the control of induced disorders by dietary cholesterol and/or lipids.