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Relationship between Handgrip Strength and Cardiopulmonary Fitness in Patients with Myocardial Infarction

심근 경색 환자에서의 손의 근력과 심폐기능의 연관성

  • Kim, JiHee (Department of Rehabilitation Medicine, Wonkwang University School of Medicine)
  • 김지희 (원광대학교 의과대학 재활의학과교실)
  • Received : 2018.07.19
  • Accepted : 2018.10.05
  • Published : 2018.10.31

Abstract

This study was conducted to investigate the relationship between hand grip strength and cardiopulmonary fitness in patients with myocardial infarction. In this retrospective study, 67 patients who experienced myocardial infarction for 10 months were analyzed. Hand grip strength was measured using a handheld dynamometer. Dynapenia was diagnosed based on a dominant hand grip strength of less than 30 kg for males and 20 kg for females. A cardiopulmonary exercise test was performed using a treadmill. Physical activity status was also evaluated. Cardiorespiratory fitness parameters were analyzed using a t-test and a Mann-Whitney test. VO2max, METmax, and exercise time significantly decreased in the dynapenia group compared with the non-dynapenia group. Correlation analysis revealed that dominant handgrip strength was significantly related to cardiorespiratory fitness parameters. Moreover, VO2max, METmax, and exercise time were significantly increased in patients with vigorous activity compared with the sedentary group. These findings indicate that handgrip strength could potentially be used as a marker of cardiorespiratory functions. Accordingly, patients with myocardial infarction should be evaluated for grip strength and physical activity, and we can encourage patients to participate actively in cardiac rehabilitation.

본 이 연구의 목적은 심근 경색증 환자에서 손의 악력과 심폐 기능의 관련성을 알아보는 것이다. 본 후향적 연구에서는 10개월간 심근 경색을 경험한 총 67 명의 자료를 분석하였다. 손의 악력은 휴대용 동력계로 측정되었다. 운동신경감소증(dynapenia)는 우성 손의 악력을 기준으로 남성의 경우 30kg 미만, 여성의 경우 20kg 미만일 경우 진단하였다. 심폐 운동검사는 트레드밀과 수정 된 Bruce 프로토콜에 따라 수행되었다. 신체활동척도로는 국제 신체활동설문을 사용하여 평가 하였다. 67 명의 대상자 중 60 명은 남성, 7 명은 여성이었고 평균 연령은 $56{\pm}9$ 세였다. 운동신경감소증군과 정상인군을 t-test와 Mann-Whitney test를 이용하여 심폐기능검사 결과를 분석하였고, 최대 산소 소모량, 최대 운동시의 신진대사 해당치, 운동시간 등이 운동신경감소증군에서 의미있게 낮았다(p<0.05). 상관관계 분석에서 손의 악력이 심폐능력과 유의한 관련이 있음을 보여 주었다. 최대산소 소모량, 최대 신지대사 해당치, 운동 시간은 고 신체활동 군에서 저 신체 활동군에 비해 유의하게 높았다(p<0.05). 심근 경색 환자에서 손의 악력은 잠재적 심폐 기능의 지표로 사용될 수 있다. 환자들의 손의 악력과 신체활동정도를 측정하여, 적극적으로 심장 재활에 참여하도록 권장할 수 있다.

Keywords

References

  1. A. M. Clark, L. Hartling, B. Vandermeer, F. A. McAlister, "Meta-Analysis: Secondary Prevention Programs for Patients with Coronary Artery Disease", Annals of Internal Medicine, Vol.143, No.9, pp.659-72, 2005. DOI: https://dx.doi.org/10.7326/0003-4819-143-9-200511010-00010
  2. G. J. Balady, P. A. Ades, V. A. Bittner, A. Franklin, N. F. Gordon, R. J. Thomas, G. F. Tomaselli, C. W. Yancy, "Referral, Enrollment, and Delivery of Cardiac Rehabilitation/Secondary Prevention Programs at Clinical Centers and Beyond", Circulation, Vol.124, No.25, pp.2951-60, 2011. DOI: https://dx.doi.org/10.1161/CIR.0b013e31823b21e2
  3. S. L. Grace, K. L. Angevaare, R. D. Reid, P. Oh, S. Anand, M. Gupta, S. Brister, D. E. Stewart, "Effectiveness of inpatient and outpatient strategies in increasing referral and utilization of cardiac rehabilitation: a prospective, multi-site study", Implementation Science, Vol.7, No.1, Article ID 120, 2012. DOI: https://dx.doi.org/10.1186/1748-5908-7-120
  4. R. Poh, H. N. Ng, G. Loo, L. S Ooi, T. J. Yeo, R. Wong, C. H. Lee, "Cardiac Rehabilitation After Percutaneous Coronary Intervention in a Multiethnic Asian Country: Enrollment and Barriers", Archives of Physical Medicine and Rehabilitation, Vol.96, No.9, pp.1733-1738, 2015. DOI: https://dx.doi.org/10.1016/j.apmr.2015.05.020
  5. H. W. Im, S. Baek, S. Jee, J. M. Ahn, M. W. Park, W. S. Kim, "Barriers to Outpatient Hospital-Based Cardiac Rehabilitation in Korean Patients With Acute Coronary Syndrome", Annals of Rehabilitation Medicine, Vol.42, No.1, pp.154-165, 2018. DOI: https://dx.doi.org/10.5535/arm.2018.42.1.154
  6. D. M. Resurreccion, P. Moreno-Peral, M. Gomez- Herranz, M. Rubio-Valera, L. Pastor, J. Miguel, C. de Almeida, E. Motrico, "Factors associated with non-participation in and dropout from cardiac rehabilitation programmes: a systematic review of prospective cohort studies", European Journal of Cardiovascular Nursing, pp.1-10, 2018. DOI: https://dx.doi.org/10.1177/1474515118783157
  7. C. E. Garber, B. Blissmer, M. R. Deschenes, B. A. Franklin, M. J. Lamonte, I. M. Lee, D. C. Nieman, D. P. Swain, "Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults: Guidance for Prescribing Exercise", Medicine & Science in Sports & Exercise, Vol.43, No.7, pp.1334-1359, 2011. DOI: https://dx.doi.org/10.1249/MSS.0b013e318213fefb
  8. E. G. Artero, A. S. Jackson, X. Sui, D. C. Lee, D. P. O'Connor, C. J. Lavie, T. S. Church, S. N. Blair, "Longitudinal Algorithms to Estimate Cardiorespiratory Fitness: Associations With Nonfatal Cardiovascular Disease and Disease-Specific Mortality", Journal of the American College of Cardiology, Vol.63, No.21, pp.2289-96, 2014. DOI: https://dx.doi.org/10.1016/j.jacc.2014.03.008
  9. GF Fletcher, PA Ades, P Kligfield, R Arena, GJ Balady, et al. "Exercise standards for testing and training: a scientific statement from the American Heart Association", Circulation, Vol.128, No.8, pp.873-934, 2013. DOI: https://dx.doi.org/10.1161/CIR.0b013e31829b5b44
  10. H. Valkeinen, S. Aaltonen, U. M. Kujala, "Effects of exercise training on oxygen uptake in coronary heart disease: a systematic review and meta-analysis", Scandinavian Journal of Medicine & Science in Sports, Vol.20, No.4, pp.545-55, 2010. DOI: https://dx.doi.org/10.1111/j.1600-0838.2010.01133.x
  11. S. J. Keteyian, C. A. Brawner, P. D. Savage, J. K. Ehrman, J. S. Schairer, G. Divine, H. Aldred, K. Ophaug, P. A. Ades, "Peak aerobic capacity predicts prognosis in patients with coronary heart disease", American Heart Journal, Vol.156, No.2, pp.292-300, 2008. DOI: https://dx.doi.org/10.1016/j.ahj.2008.03.017
  12. I. H. Rosenberg, "Summary comments", The American Journal of Clinical Nutrition, Vol.50, No.5, pp.1231-1233, 1989. DOI: https://dx.doi.org/10.1093/ajcn/50.5.1231
  13. T. N. Kim, M. S. Park, Y. J. Kim, E. J. Lee, M. K. Kim, J. M. Kim, K. S. Ko, B. D. Rhee, J. C. Won, "Association of Low Muscle Mass and Combined Low Muscle Mass and Visceral Obesity with Low Cardiorespiratory Fitness", PLOS ONE, Vol.9, No.6, Article ID e100118, 2014. DOI: https://dx.doi.org/10.1371/journal.pone.0100118
  14. B. C. Clark, T. M. Manini, "Sarcopenia=/=dynapenia", J Gerontol A Biol Sci Med Sci, Vol.63, No.8, pp.829-34, 2008. https://doi.org/10.1093/gerona/63.8.829
  15. Q. L. Xue, B. A. Beamer, P. H. M. Chaves, J. M. Guralnik, L. P. Fried, "Heterogeneity in Rate of Decline in Grip, Hip, and Knee Strength and the Risk of All- Cause Mortality: The Women's Health and Aging Study II", Journal of American Geriatric Society, Vol.58, No.11, pp.2076-84, 2010. DOI: https://dx.doi.org/10.1111/j.1532-5415.2010.03154.x
  16. C. A. Celis-Morales, D. M. Lyall, J. Anderson, S. Iliondromiti, Y. Fan, U. E. Ntuk, D. F. Mackay, J. P. Pell, N. Sattar, J. M. R. Gil, "The association between physical activity and risk of mortality is modulated by grip strength and cardiorespiratory fitness: evidence from 498 135 UK-Biobank participants", European Heart Journal, Vol.38, No.2, pp.116-122, 2017. DOI: https://dx.doi.org/10.1093/eurheartj/ehw249
  17. M. F. Piepoli, A. W. Hoes, S. Agewall, C. Albus, C. Brotons, A. L. Catapano, M. T. Cooney, U. Corra, B. Cosyns, C. Deaton, I. Graham, M. S. Hall, F. D. R. Hobbs, M. L. Lochen, H. Lollgen, P. Marques-Vidal, J. Perk, E. Prescott, J. Redon, D. J. Richter, N. Sattar, Y. Smulders, M. Tiberi, H. B. van der Worp, I. van Dis, W. M. M. Verschuren, S. Binno, "2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts)Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)", European Heart Journal, Vol.37, No.29, pp.2315-2381, 2016. DOI: https://dx.doi.org/10.1093/eurheartj/ehw106
  18. C. Pitsavos, S. A. Kavouras, D. B. Panagiotakos, S. Arapi, C. A. Anastasiou, S. Zombolos, P. Stravopodis, Y. Mantas, Y. Kogias, A. Antonoulas, C. Stefanadis, "Physical Activity Status and Acute Coronary Syndromes Survival: The GREECS (Greek Study of Acute Coronary Syndromes) Study", Journal of the American College of Cardiology, Vol.51, No.21, pp.2034-2039, 2008. DOI: https://dx.doi.org/10.1016/j.jacc.2008.01.053
  19. R. S. Taylor, B. Unal, J. A. Critchley, S. Capewell, "Mortality reductions in patients receiving exercise-based cardiac rehabilitation: how much can be attributed to cardiovascular risk factor improvements?", Eur J Cardiovasc Prev Rehabil, Vol.13, No.3, pp.369-74, 2006. https://doi.org/10.1097/00149831-200606000-00012
  20. A. J. Cruz-Jentoft, J. P. Baeyens, J. M. Bauer, Y. Boirie, T. Cederholm, F. Landi, F. C. Martin, J. P. Michel, Y. Rolland, S. M. Schneider, E. Topinkova, M. Vandewoude, M. Zamboni, "Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People", Age and Ageing, Vol.39, No.4, pp.412-23, 2010. DOI: https://dx.doi.org/10.1093/ageing/afq034
  21. www.ipaq.ki.se
  22. J. Y. Oh, B. S. Kim, J. H. Kang, Y. Y. Yang, "Validity and Reliability of Korean Version of International Physical Activity Questionnaire (IPAQ) Short Form", The Korean Academy of Family Medicine, Vol.28, No.7, pp.532-541, 2007.
  23. B. A. Franklin, C. J. Lavie, R. W. Squires, R. V. Milani, "Exercise-Based Cardiac Rehabilitation and Improvements in Cardiorespiratory Fitness: Implications Regarding Patient Benefit", Mayo Clinic Proceedings, Vol.88, No.5, pp.431-437, 2013. DOI: https://dx.doi.org/10.1016/j.mayocp.2013.03.009
  24. K. Goel, R. J. Lennon, R. T. Tilbury, R. W. Squires, R. J. Thomas, "Impact of Cardiac Rehabilitation on Mortality and Cardiovascular Events After Percutaneous Coronary Intervention in the Community", Circulation, Vol.123, No.21, pp.2344-952, 2011. DOI: https://dx.doi.org/10.1161/CIRCULATIONAHA.110.983536
  25. L. Vanhees, R. Fagard, L. Thijs, J. Staessen, A. Amery, "Prognostic significance of peak exercise capacity in patients with coronary artery disease", Journal of American College Cardiology, Vol.23 No.2, pp.358-363, 1994. DOI: https://dx.doi.org/10.1016/0735-1097(94)90420-0
  26. A. Mezzani, P. Agostoni, A. Cohen-Solal, U. Corra, A. Jegier, E. Kouidi, S. Mazic, P. Meurin, M. Piepoli, A. Simon, C. Van Laethem, L. Vanhees, "Standards for the use of cardiopulmonary exercise testing for the functional evaluation of cardiac patients: a report from the Exercise Physiology Section of the European Association for Cardiovascular Prevention and Rehabilitation", European Journal of Preventive Cardiology, Vol.16 No.3, pp.249-67, 2009. DOI: https://dx.doi.org/10.1097/HJR.0b013e32832914c8
  27. J. Myer, M. Prakash, V. Froelicher, D. Do, S. Partington, J. E. Atwood, "Exercise Capacity and Mortality among Men Referred for Exercise Testing", The New England Journal of Medicine, Vol.346, No.11, pp.793-801, 2002. DOI: https://dx.doi.org/10.1056/NEJMoa011858
  28. J. P. Clausen, "Effects of Physical Conditioning a Hypothesis Concerning Circulatory Adjustment to Exercise", Scandinavian Journal of Clinical and Laboratory Investigation, Vol.24, No.4, pp.305-13, 1969. DOI: https://dx.doi.org/10.3109/00365516909080167
  29. A. F. Osman, M. R. Mehra, C. J. Lavie, E. Nunez, R. V. Milani, "The incremental prognostic importance of body fat adjusted peak oxygen consumption in chronic heart failure", J Am Coll Cardiol, Vol.36, No.7, pp.2126-2131, 2000. https://doi.org/10.1016/S0735-1097(00)00985-2
  30. M. Cicoira, L. Zanolla, L. Franceschini, A. Rossi, G. Golia, M. Zamboni, P. Tosoni, P. Zardini, "Skeletal muscle mass independently predicts peak oxygen consumption and ventilatory response during exercise in noncachectic patients with chronic heart failure", Journal of the American College of Cardiology, Vol.37 No.8, pp.2280-85, 2001. DOI: https://dx.doi.org/10.1016/s0735-1097(01)01306-7
  31. K. Kamiya, A. Mezzani, K. Hotta, R. Shimizu, D. Kamekawa, C. Noda, M. Yamaoka-Tojo, A. Matsunaga, T. Masuda, "Quadriceps isometric strength as a predictor of exercise capacity in coronary artery disease patients", European Journal of Preventive Cardiology, Vol.21, No.10, pp.1285-1291, 2014. DOI: https://dx.doi.org/10.1177/2047487313492252
  32. K. Kamiya, T. Masuda, S. Tanaka, N. Hamazaki, Y. Matsue, A. Mezzani, R. Matsuzawa, K. Nozaki, E. Maekawa, C. Noda, M. Yamaoka-Tojo, Y. Arai, A. Matsunaga, T. Izumi, J. Ako, "Quadriceps Strength as a Predictor of Mortality in Coronary Artery Disease", The American Journal of Medicine, Vol.128, No.11, pp.1212-1219, 2015. DOI: https://dx.doi.org/10.1016/j.amjmed.2015.06.035
  33. S. Yamamoto, A. Matsunaga, K. Kamiya, K. Miida, Y. Ebina, K. Hotta, R. Shimizu, R. Matsuzawa, Y. Abe, M. Kimura, S. Shimizu, H. Watanabe, C. Noda, M. Yamaoka-Tojo, T. Masuda, T. Izumi, "Walking Speed in Patients With First Acute Myocardial Infarction Who Participated in a Supervised Cardiac Rehabilitation Program After Coronary Intervention", International Heart Journal, Vol.53, No.6, pp.347-52, 2012. DOI: https://dx.doi.org/10.1536/ihj.53.347
  34. K. Izawa, Y. Hirano, S. Yamada, K. Oka, K. Omiya, S. Iijima. "Improvement in Physiological Outcomes and Health-Related Quality of Life Following Cardiac Rehabilitation in Patients With Acute Myocardial Infarction", Circulation Journal, Vol.68, No.4, pp.315-20, 2004. DOI: https://dx.doi.org/10.1253/circj.68.315
  35. K. J. Adams, K. L. Barnard, A. M. Swank, E. Mann, M. R. Kushnick, D. M. Denny, "Combined High-Intensity Strength and Aerobic Training in Diverse Phase II Cardiac Rehabilitation Patients", Journal of Cardiopulmonary Rehabilitation, Vol.19, No.4, pp.209-15, 1999. DOI: https://dx.doi.org/10.1097/00008483-199907000-00001
  36. D. P. Leong, K. K. Teo, S. Rangarajan, P. Lopez-Jaramillo, A. Avezum Jr, A. Orlandini, P. Seron, S. H. Ahmed, A. Rosengren, R. Kelishadi, O. Rahman, S. Swaminathan, R. Iqbal, R. Gupta, S. A. Lear, A. Oguz, K. Yusoff, K. Zatonska, J. Chifamba, E. Igumbor, V. Mohan, R. M. Anjana, H. Gu, W. Li, S. Yusuf, "Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study", The Lancet, Vol.386, No.9990, pp.266-73, 2015. DOI: https://dx.doi.org/10.1016/s0140-6736(14)62000-6
  37. F. Lauretani, C. R. Russo, S. Bandinelli, B. Bartali, C. Cavazzini, A. M. Corsi, T. Rantanen, J. M. Guralnik, L. Ferrucci, "Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia", Journal of Applied Physiology, Vol.95, No.5, pp.1851-1860, 2003. DOI: https://dx.doi.org/10.1152/japplphysiol.00246.2003
  38. A. A. Motivala, U. Tamhane, V. S. Ramanath, F. Saab, D. G. Montgomery, J. Fang, E. Kline-Rogers, N. May, G. Ng, J. Froehlich, H. Gurm, K. A. Eagle, "A prior myocardial infarction: how does it affect management and outcomes in recurrent acute coronary syndromes?", Clinical Cardiology, Vol.31, No.12, pp.590-596, 2008. DOI: https://dx.doi.org/10.1002/clc.20356
  39. JCS Joint Working Group, "Guidelines for rehabilitation in patients with cardiovascular disease(JCS 2012)", Circulation Journal, Vol.78, No.8, pp.2022-2093, 2014. DOI: https://dx.doi.org/10.1253/circj.CJ-66-0094
  40. A. H. Herdy, F. Lopez-Jimenez, C. P. Terzic, M. Milani, R. Stein, T. Carvalho, S. Serra, C. G. Araujo, P. C. Zeballos, C. V. Anchique, G. Burdiat, K. Gonzalez, G. Gonzalez, R. Fernandez, C. Santibanez, J. P. Rodriguez-Escudero, H. Ilarraza-Lomeli, "South American guidelines for cardiovascular disease prevention and rehabilitation", Arquivos Brasileiros de Cardiologia, Vol.103, No.2, Suppl 1, pp.1-31, 2014. DOI: https://dx.doi.org/10.5935/abc.2014S003
  41. A. K. Chomistek, J. E. Manson, M. L. Stefanick, B. Lu, M. Sands-Lincoln, S. B. Going, L. Garcia, M. A. Allison, S. T. Sims, M. J. LaMonte, K. C. Johnson, C. B. Eaton, "Relationship of Sedentary Behavior and Physical Activity to Incident Cardiovascular Disease: Results from the Women's Health Initiative", Journal of the American College of Cardiology, Vol.61, No.23, pp.2246-54, 2013. DOI: https://dx.doi.org/10.1016/j.jacc.2013.03.031
  42. R. D. Reid, L. I. Morrin, A. L. Pipe, W. A. Dafoe, L. A. Higginson, A. T. Wielgosz, P. W. McDonald, R. C. Plotnikoff, K. S. Courneya, N. B. Oldridge, L. J. Beaton, S. Papadakis, M. E. S. D'Angelo, H. E. Tulloch, C. M. Blanchard, "Determinants of physical activity after hospitalization for coronary artery disease: the Tracking Exercise After Cardiac Hospitalization (TEACH) Study", European Journal of Preventive Cardiology, Vol.13, No.4, pp.529-537, 2006. DOI: https://dx.doi.org/10.1097/01.hjr.0000201513.13343.97
  43. K. P. Izawa, S. Yamada, K. Oka, S. Watanabe, K. Omiya, S. Iijima, Y. Hirano, T. Kobayashi, Y. Kasahara, H. Samejima, N. Osada, "Long-Term Exercise Maintenance, Physical Activity, and Health-Related Quality of Life After Cardiac Rehabilitation", American Journal of Physical Medicine & Rehabilitation, Vol.83, No.12, pp.884-892, 2004. DOI: https://dx.doi.org/10.1097/01.phm.0000143404.59050.11
  44. H. D. Sesso, R. S. Paffenbarger, I. M. Lee, "Physical Activity and Coronary Heart Disease in Men: The Harvard Alumni Health Study", Circulation, Vol.102, No.9, pp.975-980, 2000. DOI: https://dx.doi.org/10.1161/01.CIR.102.9.975
  45. I. M. Lee, K. M. Rexrode, N. R. Cook, J. E. Manson, J. E. Buring, "Physical activity and coronary heart disease in women: Is "No Pain, No Gain" Passe?", JAMA, Vol.285, No.11, pp.1447-1454, 2001. DOI: https://dx.doi.org/10.1001/jama.285.11.1447