• 통합자연과학논문집
• /
• 제7권2호
• /
• pp.92-102
• /
• 2014

The crystal structure of the title compounds with both coumarin and sulfonamide moieties were examined. These two groups have very special for their pharmaceutical and medicinal properties have been determined from single crystal X-ray diffraction data. In the title compound crystallizes in the monoclinic space group C2/c with unit cell dimension a = 28.633(3) ${\AA}$, b= 9.3215(7) ${\AA}$ and c= 24.590(2) ${\AA}$ [alpha & gamma=$90^{\circ}$ beta= $115.976(3)^{\circ}$]. In the structure The S1 atom shows a distorted tetrahedral geometry, with O1-S1-O2 [119.74 $(2)^{\circ}$] and N1-S1-C5 [$105.57(1)^{\circ}$] angles deviating from ideal tetrahedral values are attributed to the Thrope-Ingold effect. The sum of bond angles around N1 ($316.2(1)^{\circ}$) indicates that N1 is in sp2 hybridization. The Pyridine ring adopts boat conformation and pyran rings adopt a sofa conformation. The carboxylate group of atoms were disordered over two positions with site occupancy factors 0.598 (9):0.402 (9). Crystal structure and packing is stabilized by $C-H{\ldots}O$ intra and inter molecular hydrogen bond interactions.

• 대한화학회지
• /
• 제37권3호
• /
• pp.302-308
• /
• 1993

Calcium-palmitate의 단분자막을 압전수정결정 위에 Langmuir-Blodgett(LB) 기법으로 적층시켜 수정판의 진동수 변화로부터 LB막의 적층수를 평가할 수 있었다. 바탕용액에 Ca$^{2+}C$ 이온을 포함하는 palmitic acid(PA) 단분자막으로부터 이전 및 적층된 LB막 물질을 적외선 분광분석을 한 결과 1704 cm$^{-1}C$에서 갈라진 흡수띠가 나타나는 것으로 보아 calcium palmitate가 형성되었음을 알 수 있었다. 1580cm$^{-1}C$과 1540cm$^{-1}C$의 두 흡수띠는 각각 calcium carboxylate기의 비대칭 신축진동과 carboxylate가 수화되어 대칭강하된 것으로 확인되었다$^1$. 이사실은 X-선 회절분석에 의해서도 확인되었다. 23$^{\circ}C$ 물 속에서 LB막의 팽윤거동을 LB막이 적층된 수정진동판의 진동수 변화로부터 관측되었다. Calcium palitate LB막은 충분히 팽윤이 되었으나 hexadecanol LB막은 거의 팽윤이 되지 않았다. Calcium palmitate LB막 팽창량은 무게비로 건조 LB막의 47${\%}$였으며 calcium palmitate 단위 분자당 7개의 물분자가 결합되었다. Calcium palmitate 건조 LB막의 화학적 구조는 [CH$_3$(CH$_2$)$_{14}$COO]$_2$Ca${\cdot}$XH$_2$O이고 수화수는 1 H$_2$O였다.

• 대한화학회지
• /
• 제47권5호
• /
• pp.439-446
• /
• 2003

Au와 Ag 콜로이드 단일막 표면위에 흡착된 4-biphenylcarboxylic acid(BPCA)의 유도체인 4''-cyano-BPCA(c-BPCA), 4''-mercapto-BPCA(m-BPCA), 그리고 4''-amino-BPCA(a-BPCA)가 어떠한 배향을 하는지 알아보기 위해 표면증강라만(SER)분광법을 이용하여 연구하였다. 체계적인 분석을 위해 benzoic acid, biphenyl, 그리고 BPCA의 분자 배향에 대한 정보를 기본으로 위 분자들에 대한 흡착정보를 유추해내었다. 배향에 대한 정보를 위해 벤젠고리 모드, C-H 신축진동모드, carboxylate 음이온의 신축진동모드, 그리고 각각의 주요 작용기에 해당되는 모드들의 거동변화를 살펴보았으며 이로부터 m-BPCA는 thiol 그룹이 금속에 흡착되고 biphenyl 그룹이 기울어 서 있는 형태를 취하고 있고 나머지 분자들은 금속표면에 편평한 형태로 흡착됨을 알아내었다.

• Journal of the Korean Wood Science and Technology
• /
• 제48권2호
• /
• pp.231-244
• /
• 2020

As a way of finding value-added materials from waste medium density fiberboard (MDF), this study characterized cellulose nanocrystals (CNCs) isolated by ammonium persulfate (APS) oxidation using recycled MDF fibers. Chemical composition of the recycled MDF fibers was done to quantify α-cellulose, hemicellulose, lignin, nitrogen, ash and extractives. The APS oxidation was performed at 60 ℃ for 16 h, followed by ultrasonication, which resulted in a CNC yield of 11%. Transmission electron microscope images showed that rod-like CNCs had an average length and diameter of 167±47 nm and 8.24±2.28 nm, respectively, which gave an aspect ratio of about 20. The conductometric titration of aqueous CNCs suspension resulted in a carboxyl content of 0.24 mmol/g and the degree of oxidation was 0.04. Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy clearly showed the presence of carboxyl group on the CNCs prepared by the APS oxidation. The change of pH of the aqueous CNC suspension from 4 to 7 converted the carboxyl group to sodium carboxylate group. These results showed that the APS oxidation was facile and CNCs had a one-step preparation method, and thus suggested an optimization of the oxidation condition in future.

• 약학회지
• /
• 제34권2호
• /
• pp.69-79
• /
• 1990

The aim of this experiment is to observe the toxicity of cypermethrin[S, R- -cyano-3-phenoxybenzyl-(1R, 1s, cis, trans)-2,2-dimethyl-3-(2,2-dichlorovinyl) cyclopropane carboxylate]and to investigate the synergistic effect of piperonyl butoxide on the cypermethrin toxicity. In cypermethrin (CYP) treated group, the biochemical parameters such as ALT, LDH, glucose in serum were remarkably elevated. The content of cytochrome P-450 and activity of NADPH-cytochrome c reductase in renal microsomal fraction were increased but those in hepatic microsomal fraction were not significantly increased. The activity of aniline hydroxylase and ATPase in liver were decreased. In the case of CYP plus piperonyl butoxide (PB) treated group, AST, ALT, LDH and glucose were more increased. Cytochrome P-450 and NADPH-cytochrome c reductase in liver and kidney were supressed and aniline hydroxylase and ATPase in liver were more decreased. Especially, in the case of CYP plus PB 100 mg/kg treated group, hepatic TBA value was increased but activity of glucose-6-phosphatase was remarkably depressed.

• 대한환경공학회지
• /
• 제35권10호
• /
• pp.687-693
• /
• 2013

다양한 난개발과 해안도로, 방파제 등의 인공 구조물 설치로 인한 해안 침식과 해안선 파괴 등으로 해안사구가 크게 훼손되고 있다. 이에 본 연구에서는 해안사구에서 서식하고 있는 토착식물의 근권으로부터 식물 성장 촉진 능력이 있으면서 동시에 염분에 강한 내성을 가지는 근권세균의 library를 구축하였고, 이들 균주를 대상으로 식물 성장 촉진 능력을 평가하였다. 또한, 내염성 식물을 대상으로 사구 토양에서의 성장률에 근권세균이 미치는 영향을 평가한 후, 훼손된 사구의 복원에 가장 유용한 미생물을 선별하고 분리된 근권세균이 식물 성장에 미치는 영향을 평가하였다. 실험은 선정된 균주와 갯기름나물과 줄무늬갈대를 해안사구에 식재한 후 성장에 미치는 영향을 평가하였다. 그 결과, MH1RS1는 (IAA) production, siderophores, 1-aminocyclopropane-1-carboxylate deaminase (ACC deaminase) 그리고 염분내성을 가지고 있다. 갯기름나물의 경우는 줄기의 길이와 뿌리의 무게는 크게 향상되었다. 특히, 줄기의 생체와 뿌리 무게는 control과 비교했을 때 25% 성장이 향상되었다. 줄무늬 갈대는 Bacillus aerius MH1RS1 에 의해 초장은 18%와 뿌리의 생체 중은 20%로 크게 향상 되었다.

• 한국자기공명학회논문지
• /
• 제21권4호
• /
• pp.135-138
• /
• 2017

Titanium phenoxide and titanium carboxylate derivatives were prepared by ligand exchange of titanium tetraisopropoxide with the corresponding phenol and carboxylic acids. The substitution reactions were analyzed by NMR focused in the liberation of isopropylalcohol. The chemical shift of secondary proton of isopropyl group shifted to upfield after liberation; from 4.47 ppm at titanium-bound to 4.1~4.3 ppm at free alcohol state in $CDCl_3$. The substitution reaction of titanium tetraisopropoxide with carboxylic acid was applied to form dye-Ti complex for dye-sensitized solar cell.

• 통합자연과학논문집
• /
• 제8권4호
• /
• pp.250-257
• /
• 2015

The crystal structure of the potential active 3-(4-ethylphenyl)-3H-chromeno[4,3-c]isoxazole-3a(4H)-carbonitrile ($C_{19}H_{16}N_2O_2$) has been determined from single crystal X-ray diffraction data. In the title compound crystallizes in the monoclinic space group $P2_1/c$ with unit cell dimension a=6.6869 (8) ${\AA}$, b=15.8326 (19) ${\AA}$ and c= 15.237 (2) ${\AA}$ [${\alpha}=90^{\circ}$, ${\beta}=100.663^{\circ}$ and ${\gamma}=90^{\circ}$]. In the structure chromene, isoxazole and carboxylate are almost coplanar each other. All geometrical parameters revelled that chromene ring of pyran ring adopt sofa conformation. The crystal packing is stabilized by intermolecular C-H...N and C-H...O hydrogen bond interaction.

• 한국지하수토양환경학회:학술대회논문집
• /
• 한국지하수토양환경학회 2001년도 총회 및 춘계학술발표회
• /
• pp.45-48
• /
• 2001

The packed column experiments were conducted with a field soil, collected directly from the aquifer located at Bonchon industrial complex in K-city in order to characterize SOM reaction with ozone and to delineate the transformation of water soluble SOM after ozonation. As reaction time increased, water soluble organic matter increased, and this organic matter was in the range of 500∼1000 dalton. pH of extractants decreased with the increase of ozonation time. This Is because aromtic compounds in SOM were oxidized and carboxylic acid groups were formed. From the FT-IR spectra, the content of carboxylate increased as ozone injection time increased and hydroxyl group, which represents phenolic and alcoholic hydroxyl groups decreased. This is because oxidative ring fission formed carboxyl acid groups. This result provides a good agreement with pH decrease.

• 약학회지
• /
• 제34권2호
• /
• pp.80-87
• /
• 1990

3-Substituted 5-aminoisoxazole-4-carboxylates were prepared by the reaction of corresponding bormoaldoximes with cyanoacetate. The 3-trifluoromethylisoxazole derivatives were acylated to amides with various aminopyridine derivatives to afford diamides. The ester group was hydrolyzed and decarboxylated easily to give 3-trifluoromethyl-5-aminoisoxazole. The aminoisoxazole was also converted to amides. 5-Amino-3-trifluoromethylisoxazole-5-one-4-carboxylate was prepared by the reaction of trifluoroacetoaldoximoyl bromide and malonate. 5-Amino-3-methylisoxazole-5-one-4-acetate was prepared by the reaction of hydroxylamine and acetylmalonate. The synthesized compounds were tested for antiinflammatory activities.