• Title/Summary/Keyword: Capture efficiency

Search Result 336, Processing Time 0.028 seconds

A Universal Analysis Pipeline for Hybrid Capture-Based Targeted Sequencing Data with Unique Molecular Indexes

  • Kim, Min-Jung;Kim, Si-Cho;Kim, Young-Joon
    • Genomics & Informatics
    • /
    • v.16 no.4
    • /
    • pp.29.1-29.5
    • /
    • 2018
  • Hybrid capture-based targeted sequencing is being used increasingly for genomic variant profiling in tumor patients. Unique molecular index (UMI) technology has recently been developed and helps to increase the accuracy of variant calling by minimizing polymerase chain reaction biases and sequencing errors. However, UMI-adopted targeted sequencing data analysis is slightly different from the methods for other types of omics data, and its pipeline for variant calling is still being optimized in various study groups for their own purposes. Due to this provincial usage of tools, our group built an analysis pipeline for global application to many studies of targeted sequencing generated with different methods. First, we generated hybrid capture-based data using genomic DNA extracted from tumor tissues of colorectal cancer patients. Sequencing libraries were prepared and pooled together, and an 8-plexed capture library was processed to the enrichment step before 150-bp paired-end sequencing with Illumina HiSeq series. For the analysis, we evaluated several published tools. We focused mainly on the compatibility of the input and output of each tool. Finally, our laboratory built an analysis pipeline specialized for UMI-adopted data. Through this pipeline, we were able to estimate even on-target rates and filtered consensus reads for more accurate variant calling. These results suggest the potential of our analysis pipeline in the precise examination of the quality and efficiency of conducted experiments.

Factors affecting feeding activity of grey herons in a reservoir during the breeding season

  • Choi, Yu-Seong;Yoo, Jeong-Chil
    • Journal of Ecology and Environment
    • /
    • v.34 no.4
    • /
    • pp.357-363
    • /
    • 2011
  • To examine factors affecting feeding efficiency of grey herons (Ardea cinerea), the foraging behavior was studied at a reservoir in Asan city, Chungcheongnam-do, South Korea during the breeding seasons (from April to July) of 2006 and 2007. Four factors (age of foraging birds, time of day, breeding stage, and microhabitat type) were analyzed. Adults were more efficient foragers than recently fledged juveniles, and they had a higher success rate than juveniles. About half of the adults caught large prey, whereas most juveniles caught only small prey. Adult grey herons had different feeding efficiency according to the breeding stage. Pecking and capture rates were high during the late period (fledging stage), and biomass intake rates were high during the early (incubating stage) and late periods. However, time of day had no significant effect on foraging activity of adult grey herons. Feeding activities of adult grey herons also showed significant variation among microhabitat types. Pecking and capture rates were higher in the submerged plants area, but capture success rate and biomass intake rate were not different according to microhabitat type.

A passive tracking filter in a capture guidance mode (초기 유도용 수동추적 필터)

  • 엄태윤;안조영;송택렬
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 1989.10a
    • /
    • pp.99-104
    • /
    • 1989
  • A practical filter is suggested for ground-Dasea missile tracking in a capture guidance mode, utilizing angle-only measurements from a passive sensor and its performance is evaluated by a realistic system simulation study. Also suggested is a missile acceleration model that provides inputs to the filter. The suggested filter has a decoupled structure of independent azimuth and elevation channels with efficiency in commutation time and memory requirements.

  • PDF

Investigation of Applying Technical Measures for Improving Energy Efficiency Design Index (EEDI) for KCS and KVLCC2

  • Jun-Yup Park;Jong-Yeon Jung;Yu-Taek Seo
    • Journal of Ocean Engineering and Technology
    • /
    • v.37 no.2
    • /
    • pp.58-67
    • /
    • 2023
  • While extensive research is being conducted to reduce greenhouse gases in industrial fields, the International Maritime Organization (IMO) has implemented regulations to actively reduce CO2 emissions from ships, such as energy efficiency design index (EEDI), energy efficiency existing ship index (EEXI), energy efficiency operational indicator (EEOI), and carbon intensity indicator (CII). These regulations play an important role for the design and operation of ships. However, the calculation of the index and indicator might be complex depending on the types and size of the ship. Here, to calculate the EEDI of two target vessels, first, the ships were set as Deadweight (DWT) 50K container and 300K very large crude-oil carrier (VLCC) considering the type and size of those ships along with the engine types and power. Equations and parameters from the marine pollution treaty (MARPOL) Annex VI, IMO marine environment protection committee (MEPC) resolution were used to estimate the EEDI and their changes. Technical measures were subsequently applied to satisfy the IMO regulations, such as reducing speed, energy saving devices (ESD), and onboard CO2 capture system. Process simulation model using Aspen Plus v10 was developed for the onboard CO2 capture system. The obtained results suggested that the fuel change from Marine diesel oil (MDO) to liquefied natural gas (LNG) was the most effective way to reduce EEDI, considering the limited supply of the alternative clean fuels. Decreasing ship speed was the next effective option to meet the regulation until Phase 4. In case of container, the attained EEDI while converting fuel from Diesel oil (DO) to LNG was reduced by 27.35%. With speed reduction, the EEDI was improved by 21.76% of the EEDI based on DO. Pertaining to VLCC, 27.31% and 22.10% improvements were observed, which were comparable to those for the container. However, for both vessels, additional measure is required to meet Phase 5, demanding the reduction of 70%. Therefore, onboard CO2 capture system was designed for both KCS (Korea Research Institute of Ships & Ocean Engineering (KRISO) container ship) and KVLCC2 (KRISO VLCC) to meet the Phase 5 standard in the process simulation. The absorber column was designed with a diameter of 1.2-3.5 m and height of 11.3 m. The stripper column was 0.6-1.5 m in diameter and 8.8-9.6 m in height. The obtained results suggested that a combination of ESD, speed reduction, and fuel change was effective for reducing the EEDI; and onboard CO2 capture system may be required for Phase 5.

Process Improvement and Evaluation of 0.1 MW-scale Test Bed using Amine Solvent for Post-combustion CO2 Capture (0.1 MW급 연소후 습식아민 CO2 포집 Test Bed 공정개선효과 검증)

  • Park, Jong Min;Cho, Seong Pill;Lim, Ta Young;Lee, Young ill
    • KEPCO Journal on Electric Power and Energy
    • /
    • v.2 no.1
    • /
    • pp.103-108
    • /
    • 2016
  • Carbon Capture and Storage technologies are recognized as key solution to meet greenhouse gas emission standards to avoid climate change. Although MEA (monoethanolamine) is an effective amine solvent in $CO_2$ capture process, the application is limited by high energy consumption, i.e., reduction of 10% of efficiency of coal-fired power plants. Therefore the development of new solvent and improvement of $CO_2$ capture process are positively necessary. In this study, improvement of $CO_2$ capture process was investigated and applied to Test Bed for reducing energy consumption. Previously reported technologies were examined and prospective methods were determined by simulation. Among the prospective methods, four applicable methods were selected for applying to 0.1 MW Test Bed, such as change of packing material in absorption column, installing the Intercooling System to absorption column, installing Rich Amine Heater and remodeling of Amines Heat Exchanger. After the improvement construction of 0.1 MW Test Bed, the effects of each suggested method were evaluated by experimental results.

A Study on the Development of Performance Evaluation Method for the Stormwater Treatment Wetland (비점오염관리를 위한 강우유출수 처리습지의 성능평가방법 개발)

  • Kim, Young Ryun;Kim, Sang Dan;Lee, Suk Mo;Sung, Kijun;Song, Kyo Ook;Son, Min Ho
    • Journal of Korean Society on Water Environment
    • /
    • v.29 no.3
    • /
    • pp.354-364
    • /
    • 2013
  • The performance of the stormwater wetlands can be significantly influenced by antecedent stormwater in storage at the commencement of a stormevent. As inflows are intermittent and stochastic in nature, the evaluation of the treatment efficiency of a stormwater wetland should be considered by runoff capture and water treatment characteristics during interevent periods. In this study, analytical probabilistic model is applied to identity runoff capture rate and treatment efficiency of the stormwater wetland. To achieve this, continuous rainfall data recorded in Busan for 31 years has been analyzed to derive the runoff capture rate, and 1st order kinetic decay constants ($k_V$, 1/d) are calculated from regression analysis to identify pollutants removal during interevent periods. The results show that about 60.9% of annual average runoff is captured through the stormwater wetland. The annual average treatment efficiencies of SS, BOD, COD, TN and TP is about 11.4, 8.9, 9.8, 4.3 and 9.6%, respectively. The analytical model has been compared with the numerical model and it shows that analytical model is valid. Performance evaluation methods developed in this study has the advantages of considering characteristics of rainfall-runoff, facility type and pollutant removal.

Energy Saving and Development of an Industrial Regenerative Oxy-Fuel Combustion Furnace for CO2 Capture (에너지 절약 및 이산화탄소 포집을 위한 축열식 순산소 연소로 개발)

  • Oh, Jeongseog;Noh, Dongsoon;Lee, Daegeun;Hong, Sungkook;Yang, Jebok;Ko, Changbok;Lee, Eunkyung
    • 한국연소학회:학술대회논문집
    • /
    • 2013.06a
    • /
    • pp.121-122
    • /
    • 2013
  • In recent years, the usage of fossil fuels has caused problems of climate change and global warming. Because the combustion of fossil fuels is related to the production of greenhouse gases ($CO_2$, $CH_4$, etc.), new technology in the field of combustion is needed in order to handle the crisis of climate change and the global warming. As one of the efforts to reduce the emission of greenhouse gases, the concept of regenerative oxy-fuel combustion for energy efficiency and carbon capture was suggested, In the current study, the development of an industrial regenerative oxy-fuel combustion furnace was introduced, which has been being performed at Korea Institute of Energy Research (KIER).

  • PDF

Evaluation of Capture Efficiencies of Push-Pull Hood Systems by Cross Draft Directions and Velocities Using Smoke Visualization Technique (기류 가시화기법을 이용한 방해기류 방향과 속도에 따른 푸쉬풀 후드 효율 평가)

  • Song, Se-Wook;Kim, Tae-Hyeung;Ha, Hyun-Chul;Kang, Ho-Gyung
    • Journal of Korean Society of Occupational and Environmental Hygiene
    • /
    • v.15 no.1
    • /
    • pp.36-44
    • /
    • 2005
  • A push pull hood system is frequently applied to control contaminants evaporated from an open surface tank in recent years. Efficiency of push pull hood system is affected by various parameters, such as cross draft, vessel shapes, size of tanks surface, liquid temperature, and so on. Among these, velocity of cross draft might be one of the most influencing factor for determining the ventilation efficiency. To take account of the effect of cross draft velocities over 0.38m/s, a flow adjustment of ${\pm}$20% should be considered into the push and +20% into the pull flow system Although there are many studies about the efficiency evaluation of push pull hood system based on CFDs(Computational Fluid Dynamics) and experiments, there have been no reports regarding the influence of velocities and direction of cross-draft on push-pull hood efficiency. This study was conducted to investigate the influence of cross draft direction and velocities on the capture efficiency of the push-pull ventilation system. Smoke visualization method was used along with mock-up of push-pull hood systems to verify the ventilation efficiency by experiments. When the cross-draft blew from the same origins of the push flows, the efficiency of the system was in it's high value, but it was decreased significantly when the cross-draft came from the opposite side of push flows Moreover, the efficiency of the system dramatically decreased when the cross-draft of open surface tank was faster than 0.4m/s.

A Research on Efficient Skeleton Retargeting Method Suitable for MetaHuman

  • Shijie Sun;Ki-Hong Kim;David-Junesok Lee
    • International Journal of Internet, Broadcasting and Communication
    • /
    • v.16 no.1
    • /
    • pp.47-54
    • /
    • 2024
  • With the rapid development of 3D animation, MetaHuman is widely used in film production, game development and VR production as a virtual human creation platform.In the animation production of virtual humans, motion capture is usually used.Since different motion capture solutions use different skeletons for motion recording, when the skeleton level of recorded animation data is different from that of MetaHuman, the animation data recorded by motion capture cannot be directly used on MetaHuman. This requires Reorient the skeletons of both.This study explores an efficient skeleton reorientation method that can maintain the accuracy of animation data by reducing the number of bone chains.In the experiment, three skeleton structures, Rokoko, Mixamo and Xsens were used for efficient redirection experiments, to compare and analyze the adaptability of different skeleton structures to the MetaHuman skeleton, and to explore which skeleton structure has the highest compatibility with the MetaHuman skeleton.This research provides an efficient skeleton reorientation idea for the production team of 3D animated video content, which can significantly reduce time costs and improve work efficiency.

Shape Design Improvement of the Rotary Cutting Machine to Improve the Dust Capturing Efficiency using CFD (회전톱 재단기의 미세먼지 집진효율 향상을 위한 형상 설계 개선)

  • Kim, G.H.;Rhee, H.N.;Jeon, W.H.
    • 한국전산유체공학회:학술대회논문집
    • /
    • 2011.05a
    • /
    • pp.508-511
    • /
    • 2011
  • Dust released from the rotating timber cutting process causes various kinds of diseases as well as safety issues. Although there were lots of efforts to reduce the amount of dust by installing large-sized dust collectors or by using expensive high-quality cutters, they proved to be not so effective. In this study we want to modify and improve the design of the rotary cutter system to prevent dust from being released to the environment as possible by using computational fluid dynamics (CFD) analysis. We have developed CFD models of the conventional cutter and several design modifications. Through the CFD analysis the characteristics of the air flow was predicted, and then the behavior of dust produced during the cutting process was analyzed for different designs. The most efficient design feature to capture dust inside the cutter as much as possible was chosen based on the CFD analysis results. Finally the prototype of the ratary saw machine was constructed and tested to check the dust capturing efficiency, which result is reasonably consistent with the predicted performance through the CFD analysis.

  • PDF