• The Journal of Asian Finance, Economics and Business
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• v.7 no.10
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• pp.803-810
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• 2020

This objective of this study is to enrich the literature by the debt ratio and enterprise performance of Joint stock companies of Vietnam National Coal and Mineral Industries Holding Corporation Limited (Vinacomin). The debt ratio is an important index of capital structure, and it influences and decides the enterprise performance. Therefore, the determination of reasonable debt ratio level is beneficial to the stable operation of Vinacomin's enterprises. Based on the research conclusion about the effect on capital structure of debt ratio from domestic and foreign scholar, collecting data from 2014-2018 of Vinacomin's enterprises as a research sample, the article conducts research on the relationship between debt ratio and business performance of Vinacomin, as measured by return on total Assets. In addition, the study uses free cash flow, company size, growth opportunity, investment opportunities, operating costs to sales ratio as control variables.The study shows the debt ratio of Joint stock companies of Vietnam National Coal and Mineral Industries Holding Corporation Limited has a negative effect on the enterprise performance. Furthermore, the research results of the article are references for Vinacomin' enterprises in the course of production and business activities, determining a reasonable debt ratio, and improving the operational performance of enterprises.

• Journal of Korean Society on Water Environment
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• v.23 no.4
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• pp.504-511
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• 2007

Built-out issue of copper processing appearing recently in the Paldang watershed is a critical problem to deteriorate the basic framework of national water management policy as well as to be simply a copper-related problem. Up to now, Korea government has invested hard and relevant upstream areas have been victimized readily in a variety of field to comply its goal of 'Safe Water Supply'. Because of the reason, the desirable water quality level of the Paldang watershed has been maintained regardless of its dense population. Paldang drinking water management policy is based on residents' understanding which is considered as a 'social capital'. The issue raised in the aspect of water quality management policy should be reviewed on the basis of the 'social capital' concept. One regarding semiconductor industry as a potential industry to export many products in 10 years insists that the industry not be a simple private business but be a prominent part for national competitiveness. There is no doubt about this opinion. However, a nation should support environmental right-to-life of its people prior to any other tasks. In other words, it is really risky to give up people's right due to economic benefits. Therefore, it should not happen to trade 'life', the dignity of man, with national competitiveness which is likely to be preferred in these days. In addition, coherent policy not to destroy 'social capital' promoting Paldang drinking water resource management policy should be maintained.

• Journal of Wetlands Research
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• v.9 no.1
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• pp.47-60
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• 2007

The rapid development of economy in China at the expense of consuming huge amount of energy and resources, water resource in particular, which has resulted in the production and discharge of increasing amount of wastewater to the water environment. In order to effectively control the increasing water pollution trend, the State Council has stipulated that all the cities with population over 500,000 should reach wastewater treatment rate of 60% by 2005, and all the cities should reach the rate of 60% by 2010, of which Capital Beijing and all the province capital cities and important tourism cities should reach 70% then. By the end of 2005, of the 661 cities in China, 393 have built and operated municipal wastewater treatments with a total number of 790 sets, total treatment capacity of $80.91{\times}106m^3/d$ and total treatment rate of > 48%. Other 73 cities have started the construction of municipal wastewater treatment plants, and other 168 cities have started to prepare, planning and design of wastewater treatment plants. Most of municipal wastewater treatment plants in big cities in China operate normally and perform well with good quality of effluent in terms of wastewater treatment train, but the sewage sludge treatment is usually poor with big problems. It has been found that the small scale WWTPs using activated sludge process in the towns are usually operated and maintained abnormally because of lack of fund, skilled operators and energy. It is therefore suggested that the small scale MWWTPs in small cities and towns adopt appropriate technologies, of which the most available ones are multi-stage ponds, constructed wetlands and the combination of them for further purification and reuse of treated wastewater.

• Journal of Digital Convergence
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• v.17 no.3
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• pp.191-204
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• 2019

This study empirically confirmed whether individual characteristics and social capital have distinctive influence on entrepreneurship and entrepreneurship, and whether entrepreneurship consulting has a moderating effect in the context of high interest in entrepreneurship with 223 data. All of the personal characteristics, network, trust, and consulting experience had a significant influence on the entrepreneurial intention, while the external control and reciprocity norms had a significant influence on the entrepreneurial anxiety. The experience of consulting revealed that it has a moderating effect of weakening influence of risk-taking tendency and network on the entrepreneurial will and strengthening the influence of external control on the entrepreneurial anxiety. This research has significance in terms of distinguishing effects of entrepreneurial intention and anxiety and the moderating effect of consulting. In future research, it is expected that verification of entrepreneurial anxiety should be done.

• Tuberculosis and Respiratory Diseases
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• v.65 no.6
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• pp.453-456
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• 2008

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9805-9812
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• 2014

Radixin, a member of the ERM (ezrin-radixin-moesin) family, plays important roles in cell motility, invasion and tumor progression. It is expressed in a variety of normal and neoplastic cells, including many types of epithelial and lymphoid examples. However, its function in glioblastomas remains elusive. Thus, in this study, radixin gene expression was first examined in the glioblastoma cells, then suppressed with a lentivirus-mediated short-hairpin RNA (shRNA) method.We found that there were high levels of radixin expression in glioblastoma U251cells. Radixin shRNA caused down-regulation of radixin gene expression and when radixin-silenced cells were implanted into nude mice, tumor growth was significantly inhibited as compared to blank control cells or nonsense shRNA cells. In addition, microvessel density in the tumors was significantly reduced. Thrombospondin-1 (TSP-1) and E-cadherin were up-regulated in radixin- suppressed glioblastoma U251 cells. In contrast, MMP9 was down-regulated. Taken together, our findings suggest that radixin is involved in GBM cell migration and invasion, and implicate TSP-1, E-cadherin and MMP9 as metastasis-inducing factors.

• Journal of Korean Neurosurgical Society
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• v.48 no.6
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• pp.501-505
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• 2010

Objective : This study was undertaken to compare the diagnostic performances of magnetic resonance imaging (MRI), MR myelography (MRM) and myelography in young soldiers with a herniated lumbar disc (HLD). Methods : Sixty-five male soldiers with HLD comprised the study cohort. A visual analogue scale for low back pain (VAS-LBP), VAS for leg radiating pain (VAS-LP), and Oswestry disability index (ODI) were applied. Lumbar MR, MRM, and myelographic findings were checked and evaluated by four independent radiologists, respectively. Each radiologist was asked to score (1 to 5) the degree of disc protrusion and nerve root compression using modified grading systems devised by the North American Spine Society and Pfirrmann and the physical examination rules for conscription in the Republic of Korea. Correlated coefficients between clinical and radiological factors were calculated. Interpretational reproducibility between MRI and myelography by four bases were calculated and compared. Results : Mean patient age was $20.5{\pm}1.1$. Mean VAS-LBP and VAS-LP were $6.7{\pm}1.6$ and $7.4{\pm}1.7$, respectively. Mean ODI was $48.0{\pm}16.2%$. Mean MRI, MRM, and myelography scores were $3.3{\pm}0.9$, $3.5{\pm}1.0$, and $3.9{\pm}1.1$, respectively. All scores of diagnostic performances were significantly correlated (p < 0.05). However, none of these scores reflected the severity of patients' symptoms. There was no statistical difference of interpretational reproducibility between MRI and myelography. Conclusion : Although MRI and myelography are based on different principles, they produce similar interpretational reproducibility in young soldiers with a HLD. However, these modalities do not reflect the severity of symptoms.

• Journal of the Korean Geographical Society
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• v.31 no.3
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• pp.489-507
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• 1996

The purpose of this study is to examine the increasing number of unregistered manufacturing plants and related problems, and to recommend alternative solutions to the problems. Data are obtained from a field survey of randomly selected small scale manufacturing plants in Seoul and its suburban cities. A total number or respondents are 533, and 416 of them are unregistered plants. The Capital Regional Planning has had a goal during last three decades to lead a balanced regional economic development by restriction manufacturing plants in the Capital Region and by encouraging them in other regions in the nation. It was 1984 when a comprehensive planning was established to achieve this goal. Sets of various regulations, by-laws and codes have been implemented to regulate manu-facturing activities in the Capital Region to achieve the goal. The region is divided into three sub-regions, and a different degree of regulations is applied to each sub-region. Only a certain types of industries are allowed in a particular sub-region. For instance, a plant manufacturing high-technology products could be allowed in the most urbanized sub-region. All manu-facturing plant in the Capital Region which has ares size of larger than 200"\;"$m^2$ is compulsory to register to the local government office. In practice, however, it is not common or sometimes almost impossible to get approval for many applicant manufacturers because of strict regulations. There have been increasing number of plants in the Capital Region during last several decades, despite the strict regulations. Many of those newly established plants are without formal registration at the local administration office. howerver. These are so called 'unregisterd' plants. Surveyed data and many government official data show that many of unregistered plants have been established in recent years. which indicate that current regulations are no longer effective. The number of unregistered plants are increasing tin the Capital Region because of many locational advantages in the region for plants, particularly those in small scale. Unregistered plants are the source of many problems, such as local water pollution or noise pollution in residential areas. There are also many administration problems, bed\cause they are not registered. The central government has attempted to cure the problems of unregistered plants. For example, the government allowed a unregistered plant to remain at present site for three ydars, if it met certain conditions in three years. However, this program was unsuccessful because many of those plants were not able to meet the concitions. Three times the government renewed the term for those which did not meet conditions since 1989, but it was afraid to be without success. There are many evidences that current policies to control manufacturing plants are not effective. The Capital Region must face mounting problems if ploicies are not reformed soon. This study suggests that the policy of the Capital Regional Planning has to be reoriented to provide more favorable policies for manufacturing plants in the Capital Region than current regulations which is aimed to restrict manufacturing activities. It is time to improve many existing problems in the region through reforms and of current regulations to foster unregistered plants. This study also proposes many smaller-area sub-divisions instead of current three large area sub-regions which is too broad to apply single kind of regulation, or codes. Flexible regulations and codes can be applied to such a small-area sub-divivisions based on location and industrial characteristics of the individual sub-divisions. It is necessary to provide decent industrial environment in the Capital Region, which is best equipped to provide many favorable industrial locational factors in the nation, thus this nation can be further prepared to compete in an inter-national market at an era of globalization in manufacturing.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2043-2050
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• 2016

Exploring novel antibiotics is necessary for multidrug-resistant pathogenic bacteria. Because the probiotics in soybean food have antimicrobial activities, we investigated their effects on multidrug-resistant Acinetobacter baumannii. Nineteen multidrug-resistant A. baumannii strains were clinically isolated as an experimental group and 11 multidrug-sensitive strains as controls. The growth rates of all bacteria were determined by using the analysis for xCELLigence Real-Time Cell. The combination of antibiotics showed synergistic effects on the strains in the control group but no effect on the strains in the experimental group. Efflux pump gene adeS was absent in all the strains from the control group, whereas it exists in all the strains from the experimental group. Furthermore, all the strains lost multidrug resistance when an adeS inhibitor was used. One strain of probiotics isolated from soybean food showed high antimicrobial activity for multidrug-resistant A. baumannii. The isolated strain belongs to Bacillus subtilis according to 16S RNA analysis. Furthermore, E. coli showed multidrug resistance when it was transformed with the adeS gene from A. baumannii whereas the resistant bacteria could be inhibited completely by isolated Bacillus subtilis. Thus, probiotics from soybean food provide potential antibiotics against multidrug-resistant pathogenic bacteria.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.1
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• pp.881-889
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• 2021

The purpose of this study is to descriptively reveal the demographic and business profile and personal-entrepreneurial characteristics in Manado, the capital of North Sulawesi, and secondly to associate these profiles and characters to their business progress. A sample size of 21 respondents was drawn - selected from those who warmly welcomed the interviewers for an open-ended structured questionnaire. SPSS 24 has been employed to descriptively reveal the sample distribution according to demographic factors and business entities and to determine the dominant factors affecting the progress of the business by testing the hypothesis on the association of variables under study using specified statistical analytical tools, such as regression analysis, especially stepwise regression formula, between specified dependent variables and independent variables and /or between all variables. The stepwise regression analysis has enabled the researcher to determine which variables are the most important reflecting the personal characteristics theorized as "locus of control": self-efficacy, needs for achievement, personal traits, and barriers to business progress The analysis reveals that the progress of business does have an association and is dependent on the source of capital and education, needs for achievement and locus of control.