• Title/Summary/Keyword: Cape

Search Result 213, Processing Time 0.023 seconds

Residue Y70 of the Nitrilase Cyanide Dihydratase from Bacillus pumilus Is Critical for Formation and Activity of the Spiral Oligomer

  • Park, Jason M.;Ponder, Christian M.;Sewell, B. Trevor;Benedik, Michael J.
    • Journal of Microbiology and Biotechnology
    • /
    • v.26 no.12
    • /
    • pp.2179-2183
    • /
    • 2016
  • Nitrilases pose attractive alternatives to the chemical hydrolysis of nitrile compounds. The activity of bacterial nitrilases towards substrate is intimately tied to the formation of large spiral-shaped oligomers. In the nitrilase CynD (cyanide dihydratase) from Bacillus pumilus, mutations in a predicted oligomeric surface region altered its oligomerization and reduced its activity. One mutant, CynD Y70C, retained uniform oligomer formation however it was inactive, unlike all other inactive mutants throughout that region all of which significantly perturbed oligomer formation. It was hypothesized that Y70 is playing an additional role necessary for CynD activity beyond influencing oligomerization. Here, we performed saturation mutagenesis at residue 70 and demonstrated that only tyrosine or phenylalanine is permissible for CynD activity. Furthermore, we show that other residues at this position are not only inactive, but have altered or disrupted oligomer conformations. These results suggest that Y70's essential role in activity is independent of its role in the formation of the spiral oligomer.

Geo-location White Space Spectrum Databases: Models and Design of South Africa's First Dynamic Spectrum Access Coexistence Manager

  • Mfupe, Luzango;Mekuria, Fisseha;Mzyece, Mjumo
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.8 no.11
    • /
    • pp.3810-3836
    • /
    • 2014
  • Geo-location white space spectrum databases (GL-WSDBs) are currently the preferred technique for enabling spectrum sharing between primary users and secondary users or white space devices (WSDs) in the very-high frequency (VHF) and ultra-high frequency (UHF) bands. This is true because technologies for making low-cost WSDs capable of autonomous sensing and detection of available white space (WS) spectrum are not yet feasible. This paper reviews the necessary enabling technical conditions to allow coexistence of primary and secondary systems in the VHF and UHF spectrum through a GL-WSDB approach. The practical implementation of South Africa's first GL-WSDB was performed. Results of WS channels available from five cities in South Africa calculated from the implemented GL-WSDB was compared with a commercially available GL-WSDB and was found to be 68% similar. Additionally, results from the implemented GL-WSDB were compared with measurements obtained from field spectrum scanning campaigns at two different locations in Cape Town, South Africa, and was found to be 64% similar.

GRBAS and Voice Handicap Index (GRBAS 음성평가와 음성장애지수)

  • Sohn, Jin-Ho
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
    • /
    • v.19 no.2
    • /
    • pp.89-95
    • /
    • 2008
  • Subjective voice evaluation is necessary and important to assess the voice disorders in addition to objective voice evaluation. Subjective voice evaluation is divided into examiner and examinee subjective voice assessment. The examiner assessment represents perceptual judgment to the patient's voice such as GRBAS scale, Buffalo voice profile, consensus auditory perceptual evaluation of voice (CAPE- V) and so on. The examinee assessment consists of indirect method including voice handicap index (VHI), voice outcome survey (VOS), voice symptom scale (VoiSS), voice related quality of life (V-ROQL) and direct method which is called patient's self-subjective voice rating. This review article describes a general rule, advantages and pitfalls about GRBAS scale, VHI and patient's self-subjective voice rating which are presently most representative voice assessment tools.

  • PDF

A Case Study for Deformation of Caisson caused by Friction Shortage (케이슨 하부의 마찰저항 부족에 따른 케이슨 안벽 변위발생 사례연구)

  • Shim, Dong-Hyun;Park, Jun-Ho;Lee, Kyung-Sook
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2008.10a
    • /
    • pp.325-336
    • /
    • 2008
  • Deformation of caisson occurred during the backfilling behind the caisson and some caisson moved toward seaside. A series of site investigation were conducted to figure out various circumstances at site and also used to analyze the cause of deformation. The soil condition of backfilling is also investigated because dredged material was used as a backfill material. The friction angle of backfill is supposed to be lower than the estimated one which was used in design stage. To determine the cause of friction shortage, back analysis for sliding safety were carried out with considering the soil condition of backfilling. A remedial plan, re-rising and relocating a caisson with backfilling good earth after treatment of caisson rubble mound to achieve the safety for sliding was proposed as a best solution based on the back analysis results. Reform concrete structure including service gallery and crane rail was also considered with the remedial work to improve the cape line of caisson.

  • PDF

Fashion Accessories Designed from Recycled Fabric Remnants (소재 재활용에 의한 패션소품 디자인 개발)

  • Kim, Chan-Ju;Ro, Mi-Kyung
    • Journal of the Korean Society of Costume
    • /
    • v.60 no.10
    • /
    • pp.65-79
    • /
    • 2010
  • Each season, many clothing companies dump small pieces of fabrics left over from making samples. Since fabrics do not decompose easily, this results in environmental pollution. This research was done to discover effective ways to reuse these fabric remnants. As most of these remnants were not large enough for making clothes, fashion accessories was chosen as the design object. Four steps of design development process followed: information research & analysis, prototype design & sample making, market testing, final design decision. After market research and trend analysis, four neck decoration wear -- scarf & muffler(SM). collar & cape(CC), vest & top(VT), and necklace(NE) -- were selected as final product types. 45 designs arose, and 120 items with variations in fabric materials and colors were produced as samples. The three main themes (multiple. reversible, cross) were applied throughout all of the design items. Samples were evaluated from the reactions of the consumers through a 10-day sale at a retail store. Based on the sales record and customers' opinions, five designs from each of the product types SM, CC, and VT were picked out as final designs. In conclusion, fashion accessories turned out to be a more appropriate item to reuse fabric remnants from clothing companies than clothes were, because they necessitate small fabric size and the limitation in fabrics could be compensated with creative design ideas.

Dividinism of Collar of Costume in the Cultural Pattern of Post-Modernism (포스트모더니즘 복식 칼라에 나타난 해체주의적 경향)

  • Park, Seon-Yeong;Nam, Yun-Ja
    • Fashion & Textile Research Journal
    • /
    • v.5 no.3
    • /
    • pp.227-234
    • /
    • 2003
  • The purpose of this study is to investigate how the Post-modernism social cultural pattern has been reflected in collar of costume. In the classes social, collar in costume is the expressive medium of ideology and status symbol such as Passium of ancian Ezypt and Byzantin collar which is examined religion belif. The conspicuous function of collar can be examed as the ruff collar, which is the expressive medium of self-confidence, but the whisk collar and the flat collar means decline the authorized conspicous function. In the cultural pattern of Post-modernism, collar in costume presents the coexistence of double-sides value such as androgyny, dividinism and eclecticism. For example, the tailored collar or shirt collar in women's suit with delicate materials express the self-confidence, energy and intelligence, and the round collar or the draped collar in men's suit with rough material express the sensibility and liberty. In the deconstructivity through breaking the basis form of the collar, callar can be transformed in to sleeve, cape or hat on occasion. In conclusion, the function of collar changes by the cultural pattern and expresses the spirit.

Phytochemical Study on Aloe vera

  • Choi, Jae-Sue;Lee, Seung-Ki;Sung, Chung-Ki;Jung, Jee-Hyung
    • Archives of Pharmacal Research
    • /
    • v.19 no.2
    • /
    • pp.163-167
    • /
    • 1996
  • Aloe plants have been used as herbal medicine for centuries and the name aloe means the dried exudate from the cut leaves of Aloe ferox Mill. (Cape aloe, Liliaceae), Aloe ferryi Baker. (Socotrine aloe), A. bainesii Th. Dyer. (Natal aloe) and Aloe vera L. (Curacao aloe) (Namba, 1986). Among them, Aloe vera has not only been one of the most used natural drug well known for its cathartic properties, but also has been widely used as raw materials of cosmetics and health foods (Leung, 1978, Hoffenberg, 1979). Although previous investigations showed that the leaves of A. vera contain a number of anthracene and chromone derivatives such as aloin A, aloin B, 1, 3, 6, 8-tetra-nitro-4,5-dihydroxy-2-hydroxymethyl anthraquinone and 7-hydroxy-aloin, its chemical composition is far from being completely investigated (Hoffenberg, 1979, Rauwald and Voetig, 1982). As a part of our chemical investigations on the constituents of aloe, we report chemical investigation of the freeze dried ground leaves of A. vera which is led to the isolation of five compounds from the ethyl acetate soluble fraction of the methanolic extract.

  • PDF

Roles of Park and Green Space Planning for Establishing Livable Communities in the Environmental Age through Encouraging Linkage of Academic and Practical Approaches

  • Yoritaka Tashiro
    • Journal of the Korean Institute of Landscape Architecture International Edition
    • /
    • no.2
    • /
    • pp.74-80
    • /
    • 2004
  • The significance and means of parks and green space planning have been changed dramatically in this century in Japan. The first priority must be given to define the means and purposes of planning., especially the role of ecological, social and economical management with the increasing trend of environmental concern, and the method to estimate values of park and green space from the point of view of regenerative society development. The role of planning parks and green space is reviewed in the following three aspects; as tools for land use control (master plan), as tools for finding appropriate lands for purchasing land (development plan) and tools for application of individual development technique of green space and landscapes(site plan and design). It is a serious issue that the existence of parks in urban setting which used to be considered as a top priority, is now being challenged in terms of economical, social and environmental benefits. In such processes, the most important issue is to define what makes parks and green spaces attractive and ecological to obtain social support to be developed.

  • PDF

OCI and ROCSAT-1 Development, Operations, and Applications

  • Chen, Paul;Lee, L.S.;Lin, Shin-Fa
    • Korean Journal of Remote Sensing
    • /
    • v.15 no.4
    • /
    • pp.367-375
    • /
    • 1999
  • This paper describes the development, operations, and applications of ROCSAT-l and its Ocean Color Imager (OCI) remote-sensing payload. It is the first satellite program of NSPO. The satellite was successfully launched by Lockheed Martin's Athena on January 26, 1999 from Cape Canaveral, Florida. ROCSAT-l is a Low Earth Orbit (LEO) experimental satellite. Its circular orbit has an altitude of 600km and an inclination angle of 35 degrees. The satellite is designed to carry out scientific research missions, including ocean color imaging, experiments on ionospheric plasma and electrodynamics, and experiments using Ka-band (20∼30GHz) communication payloads. The OCI payload is utilized to observe the ocean color in 7 bands (including one redundant band) of Visible and Near-Infrared (434nm∼889nm) range with the resolution of 800m at nadir and the swath of 702km. It employs high performance telecentric optics, push-broom scanning method using Charge Coupled Devices (CCD) and large-scale integrated circuit chips. The water leaving radiance is estimated from the total inputs to the OCI, including the atmospheric scattering. The post-process estimates the water leaving radiance and generates different end products. The OCI has taken images since February 1999 after completing the early orbit checkout. Analyses have been performed to evaluate the performances of the instrument in orbit and to compare them with the pre-launch test results. This paper also briefly describes the ROCSAT-l mission operations. The spacecraft operating modes and ROCSAT Ground Segment operations are delineated, and the overall initial operations of ROCSAT-l are summarized.

Korea Pathfinder Lunar Orbiter Flight Dynamics Simulation and Rehearsal Results for Its Operational Readiness Checkout

  • Song, Young-Joo;Bae, Jonghee;Hong, SeungBum;Bang, Jun
    • Journal of Astronomy and Space Sciences
    • /
    • v.39 no.4
    • /
    • pp.181-194
    • /
    • 2022
  • Korea Pathfinder Lunar Orbiter (KPLO), also known as Danuri, was successfully launched on 4 Aug. from Cape Canaveral Space Force Station using a Space-X Falcon-9 rocket. Flight dynamics (FD) operational readiness was one of the critical parts to be checked before the flight. To demonstrate FD software's readiness and enhance the operator's contingency response capabilities, KPLO FD specialists planned, organized, and conducted four simulations and two rehearsals before the KPLO launch. For the efficiency and integrity of FD simulation and rehearsal, different sets of blind test data were prepared, including the simulated tracking measurements that incorporated dynamical model errors, maneuver execution errors, and other errors associated with a tracking system. This paper presents the simulation and rehearsal results with lessons learned for the KPLO FD operational readiness checkout. As a result, every functionality of FD operation systems is firmly secured based on the operation procedure with an enhancement of contingency operational response capability. After conducting several simulations and rehearsals, KPLO FD specialists were much more confident in the flight teams' ability to overcome the challenges in a realistic flight and FD software's reliability in flying the KPLO. Moreover, the results of this work will provide numerous insights to the FD experts willing to prepare deep space flight operations.