• 대한의용생체공학회:의공학회지
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• 제21권4호
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• pp.373-384
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• 2000

본 연구의 목적은 체적 변형률 (volumetric strain)에 의한 스폰지 뼈의 밀도를 예측하는 것이다. 스폰지 뼈의 내부에서 유체의 흐름을 고려하기 위하여 각각의 normal strain의 합을 체적 변형률로 정의하였다. 체적 변형률의 경계조건에 대한 민감한 반응은 스폰지 뼈의 밀도를 예측하도록 하였다. 이러한 이론적 배경을 유한요소법 (finite element method)에 적용시켜 대퇴골 (femur)과 척구 (spine)의 스폰지 뼈에서의 밀도를 예측하였다. 예측된 뼈의 밀도는 실험적 데이터와 매우 유사하였다. (Wolff 1892, Keller et al. 1989, Codyet al. 1992). 뼈의 밀도의 함수인 뼈의 탄성계수와 강도 또한 실험적 결과와 매우 유사하였다. (Keller et al. 1989, Carter and Hayes 1977). 본 연구에서 정립된 알고리즘은 스폰지 뼈의 밀도를 예측하는데 있어서 수렴성과 민감성이 우수하였다. 따라서 본 연구의 컴퓨터 알고리즘은 스폰지 뼈의 밀도예측에 있어서 매우 유용한 방법이 될 것이다.

• 대한두개안면성형외과학회지
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• 제23권3호
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• pp.103-110
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• 2022

Background: The primary objectives of mandibular surgery are to achieve optimal occlusion, low sensory disturbance, and adequate fixation with early movement. In-depth knowledge of the mandibular structure is required to achieve these goals. This study used computed tomography (CT) to evaluate the mandibular cortical thickness and cancellous space according to age and sex. Methods: We enrolled 230 consecutive patients, aged 20 to 50 years, who underwent CT scanning. The cortex and cancellous space centered around the inferior alveolar nerve (IAN) canal were measured at two specific locations: the lingula and second molar region. Statistical analysis of differences according to increasing age and sex was performed. Results: The t-test revealed that the cancellous space and cortical thickness differed significantly with respect to the threshold of 35 years of age. Both cortical thickness and cancellous space in the molar region were negatively correlated with age. Meanwhile, both cortical thickness and cancellous space in the lingula region showed a positive correlation with age. With respect to sex, significant differences in the cancellous space at the molar region and the cortical thickness at the lingula were observed. However, no further statistically significant differences were observed in other variables with respect to sex. The sum of each measurement on the mandibular body reflected the safe distance from the surface of the outer cortex to the IAN canal. The safe distances also showed statistically significant differences between those above and below 35 years of age. Conclusion: Knowledge of the anatomical structure of the mandible and of changes in bone structure is crucial to ensure optimal surgical outcomes and avoid damage to the IAN. CT examination is useful to identify changes in the bone structure, and these should be taken into account in the planning of surgery for older patients.

• Imaging Science in Dentistry
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• 제30권1호
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• pp.16-22
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• 2000

Purpose : To evaluate the bone densities measured on copper-equivalent image of cross sectional view of mandibular edentulous premolar area obtained by multifuctional panoramic x-ray machine, PM 2002 CC with transversal slicing system. Materials and Methods: Panoramic cross sectional views with 8 mm focal layer of aluminum step and blocks, of hydroxyapatite (RA) step, 6 HA blocks and copper step wedge having 0.03 mm thickness of each step, and of 3 bone blocks cutted by 8 mm thickness mesiodistally and a dry mandible with copper step wedge were taken by using transversal slicing system in PM 2002 Cc. All reference-equivalent images were made and analyzed by NIH image program. Results: The average copper-equivalent value of cancellous bone of bone blocks on the panoramic cross sectional view was 0.026 ± 0.020 mm Cu. The calculated average bone density was 0.38g/cm². There was no significant difference (P>0.1) between the bone densities on intraoral digital view and on the panoramic digital cross sectional view. Conclusion: The copper-equivalent image of panoramic digital cross sectional view obtained by PM 2002 CC with very thin copper step wedge was supposed to be useful to measure the bone density of cancellous bone of mandible at the premolar edentulous area.

• 생명과학회지
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• 제20권8호
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• pp.1207-1213
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• 2010

본 연구의 목적은 랫드의 두개결손부 모델에서 돼지 해면질골을 지지체로 사용했을 때의 효과를 평가해보고자 하였다. 임계결손부의 형성은 30마리의 수컷 Sprague-Dawley 랫드에서 실시하였으며 동물들은 임계결손군(CD group, n=10), 베타 삼인산칼슘군(BT group, n=10) 및 돼지 해면질골군(PCB group, n=10)으로 나누었다. 각각의 결손부위는 피브린 글루와 혼합시킨 베타 삼인산칼슘 또는 돼지 해면질골로 채워졌으며 CD군은 결손부위에 이식재를 이식하지 않았다. 모든 랫드들은 골이식 수술 8주 후에 희생되었으며 희생 후 육안검사, 단순 방사선촬영, micro-CT 촬영 및 조직검사를 통해 골형성 정도를 평가하였다. 결과에서 골결손부의 치유는 CD군에서 가장 낮았으며 PCB군에서는 유의성 있는 새로운 골형성을 확인할 수 있었다. 또한 방사선촬영 결과, 조직학적 평가 및 micro CT 촬영 결과에서 골이식 시 돼지 해면질골이 베타 삼인산칼슘보다 새로운 골형성에 있어 더욱 효과적임을 관찰할 수 있었다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제22권1호
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• pp.86-91
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• 2000

Autogenous bone graft is the useful technique for management of various bone defect in oral and maxillofacial surgery. The most common site for bone graft harvest is the anterior iliac crest. There is usually considerable cancellous bone graft available and it can be obtained with minimal morbidity. However, complications noted in iliac crest grafts include prolonged postoperative pain, hematoma and fracture, gluteal muscle weakness. Occasionally, when large amounts of bone graft are needed and previous harvest procedure had used, iliac bone harvest may be not adequate. Like the iliac crest, the greater trochanter has abundant cancellous bone and is readily accessible with acceptable morbidity. The purpose of this study was to assess the availability of cancellous bone graft from the greater trochanter, compare the quantity with that available from the anterior iliac crest, investigate anatomical hazards, and make recommendations for consistent harvest.

• Advances in biomechanics and applications
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• 제1권1호
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• pp.67-76
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• 2014

Bone properties are one of the key components when constructing models that can simulate the mechanical behavior of a mandible. Due to the complexity of the structure, the tooth, ligaments, different bones etc., some simplifications are often considered and bone properties are one of them. The objective of this study is to understand if a simplification of the problem is possible and assess its influence on mandible behavior. A cadaveric toothless mandible was used to build three computational models from CT scan information: a full cortical bone model; a cortical and cancellous bone model, and a model where the Young's modulus was obtained as function of the pixel value in a CT scan. Twelve muscle forces were applied on the mandible. Results showed that although all the models presented the same type of global behavior and proximity in some locations, the influence of cancellous bone can be seen in strain distribution. The different Young's modulus defined by the CT scan gray scale influenced the maximum and minimum strains. For modeling general behavior, a full cortical bone model can be effective. However, when cancellous bone is included, maximum values in thin regions increase the strain distribution. Results revealed that when properties are assigned to the gray scale some peaks could occur which did not represent the real situation.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제34권6호
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• pp.391-397
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• 2012

Purpose: The purpose of this study was to evaluate the effectiveness of the platelet-rich fibrin (PRF) used in combination with the porcine cancellous bone as a scaffold, in promoting bone regeneration in the bone defects ofthe rabbit calvaria. Methods: Ten rabbits were used in the study. Three round-shaped defects (diameter 8.0 mm) were created in the rabbit calvaria and were filled with nothing (control group), porcine cancellousbone (Experimental Group 1, porcine bone) and PRF-mixed porcine cancellous bone (Experimental Group 2). TS-GBB is a xenogenic bone-substitute product comprised of a high heat-treated mineralized porcine cancellous bone. Animals were sacrificed at 6 weeks and 12 weeks for the histological and radiographic evaluations. Results: In the micro computed tomography and histological results, the experimental groups 1 and 2 showed more bone formation, remodeling, and calcification than the control group. The new bone formation ratio showed theGroup 2 to be larger than Group 1 at6 and 12 weeks. However, there was no significant difference between the experimental groups 1 and 2 in the new bone formation area, at the 6 and 12 weeks (P>0.05). Conclusion: The PRF-mixed group showed more bone formation than the porcine cancellousbonegroup (TS-GBB), butthere was a no significant difference. The PRF may not lead to enhanced bone healing when grafted with the porcine cancellous bone.

• 한국음향학회:학술대회논문집
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• 한국음향학회 2004년도 추계학술발표대회논문집 제23권 2호
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• pp.183-186
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• 2004

Biot's theory and a modified Biot-Attenborough (MBA) model are applied to predict the dependences of acoustic characteristics on frequency and porosity in cancellous bone. The phase velocity and the attenuation coefficient predicted by both theories are compared with previous in vitro experimental measurements in terms of the mixed, the fast, and the slow waves. Biot's theory successfully predicts the dependences of phase velocity on frequency and porosity in cancellous bone, whereas a significant discrepancy is observed between predicted and measured attenuation coefficients. The MBA model is consistent with reported measurements for both dependences of phase velocity and attenuation coefficient on frequency and porosity. Based on the theoretical predictions from the MBA model, it is suggested that the attenuation coefficient of the mixed wave is dominated by the fast wave in the low-porosity region while it is dominated by the slow wave in the high-porosity region. This provides a qualitative explanation for the nonlinear relationship of attenuation of the mixed wave with porosity in cancellous bone.

• The Journal of the Acoustical Society of Korea
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• 제29권2E호
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• pp.64-72
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• 2010

Osteoporosis is a skeletal disease characterized by two factors: reduced bone mass and microstructure disruption of bone tissue. These symptoms increase bone fragility and can contribute to eventual fracture. In recent years, quantitative ultrasound (QUS) technologies have played a growing role in the diagnosis of osteoporosis. Most of the commercial bone sonometers measure speed of sound and/or broadband ultrasound attenuation at peripheral skeletal sites. However, QUS parameters are purely empirical measures that have not yet been firmly linked to physical parameters, such as bone strength or porosity, and the underlying physics for their variations in cancellous bone is not well understood yet. This paper reviews the QUS technologies for the diagnosis of osteoporosis and also addresses several theoretical models, such as the Biot model, the scattering model, the stratified model, and the modified Biot-Attenborough model, for ultrasonic wave propagation in bone.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제12권2호
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• pp.88-94
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• 1990

Because of it's accessibility and the quantity of bone available, the ilium is a common donor site for autogenous cancellous, cortical, and corticocancellous grafts to the facial skeleton. Especially, the anterior iliac crest has been the traditional source of pelvic bone for autogenous bone grafting in the maxillofacial skeleton. Recently the need for large amounts of bone in some reconstructive procedures of the facial skeleton has led to the evaluation of posterior ilium. The posterior approach to the ilium is superior to the anterior approach when large quantities of cancellous bone are required for facial reconstruction. The posterior approach has the advantages of more available bone, fewer complications, less postoperative pain, less disturbance in ambulation, and a possible reduction in the length of hospitalization. As the posterior approach affords an almost unlimited amount of bone for autogenous grafting in the maxillofacial region, we feel its use is indicated when very large amounts of bone are required.