• 통합자연과학논문집
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• 제5권1호
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• pp.1-5
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• 2012

Quantitative structure-activity relationship (QSAR) methodologies have been applied for many years, to correlate the relationship between physicochemical properties of chemical substances and their biological activities to generate a statistical model for prediction of the activities of new chemical entities. The basic principle behind the QSAR models is that, how structural variation is responsible for the difference in biological activities of the compounds. 3D-QSAR has emerged as a natural extension to the classical Hansch and Free-Wilson approaches, which develops the 3D properties of the ligands to predict their biological activities using various chemometric techniques (PLS, G/PLS, ANN etc). It has served as a valuable predictive tool in the design of pharmaceuticals and agrochemicals. This review seeks to provide different 3D-QSAR approaches involved in drug designing process to develop structure-activity relationships and also discussed the fundamental limitations, as well as those that might be overcome with the improved methodologies.

• 통합자연과학논문집
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• 제5권1호
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• pp.6-12
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• 2012

c-Jun N-terminal kinase-3 (JNK-3) has been identified as a promising target for neuronal apoptosis and has the effective therapeutic for neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and other CNS disorders. Herein, we report the essential structural and chemical parameters for JNK-3 inhibitors utilizing comparative molecular field similarity indices analysis (CoMSIA) using the derivatives of 3,5-disubstituted quinolines. The best predictions were obtained CoMSIA model (q2=0.834, r2=0.987) and the statistical parameters from the generated 3D-QSAR models were indicated that the data are well fitted and have high predictive ability. The resulting contour map from 3D-QSAR models might be helpful to design novel and more potent JNK3 derivatives.

• International Journal of Knowledge Content Development & Technology
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• 제8권4호
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• pp.7-18
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• 2018

Information Literacy (IL) is considered as an important aspect of everybody's life. In today's information society possessing IL skills is more significant than ever as information is available in many forms and formats. Schools are the primary places where these skills are imbibed in students. Organizations like UNESCO, IFLA, ALA, AASL, & ACRL have formulated IL Standards and Guidelines/Models at the international arena. Though the Government of India is making efforts in providing information literacy skills yet there are no set of standards/guidelines devised by any agency/organization at the school level. This paper gives a brief account of IL initiatives and highlights the trends and developments of IL programmes in Indian School Libraries. It recommends the nation to form a national level advisory committee to develop IL framework for Indian school Libraries. Further, it suggests that librarians should work in close collaboration with teachers for better results. A moderate attempt has been made to provide feasible solutions for effective implementation of IL programmes in school libraries.

• Journal of Multimedia Information System
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• 제6권2호
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• pp.87-90
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• 2019

Machine learning techniques have been applied in almost all the domains of human life to aid and enhance the problem solving capabilities of the system. The field of medical science has improved to a greater extent with the advent and application of these techniques. Efficient expert systems using various soft computing techniques like artificial neural network, Fuzzy Logic, Genetic algorithm, Hybrid system, etc. are being developed to equip medical practitioner with better and effective diagnosing capabilities. In this paper, a comparative study to evaluate the predictive performance of subtractive clustering based ANFIS hybrid system (SCANFIS) with Fuzzy C-Means (FCM) based ANFIS system (FCMANFIS) for Alzheimer disease (AD) has been taken. To evaluate the performance of these two systems, three parameters i.e. root mean square error (RMSE), prediction accuracy and precision are implemented. Experimental results demonstrated that the FCMANFIS model produce better results when compared to SCANFIS model in predictive analysis of Alzheimer disease (AD).

• Design & Manufacturing
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• 제14권4호
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• pp.1-10
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• 2020

The seal plays a role in preventing oil leakage when the lip and the rotating shaft come into contact with the fluid and air pressure. Recently, micro dimples or micro pockets are processed and used on the lubrication surfaces of thrust bearings, mechanical bearings, and piston rings. Compared to a smooth surface, micro dimples reduce friction and increase the life of parts. This paper analyzed various kinds of micro dimple shapes on the sealing surface, i.e. circle, rectangle, triangle, and trapezoid. For this purpose, Introduced the design of experiments to work out a micro dimple configuration, unlikely to be damaged from cracks and low in contact stress. As a result, the triangular dimple showed the best results. Optimal factors were dimple size 0.15 mm, dimple depth 0.0383 mm, dimple density 40%, and the maximum equivalent stress was 9.1455 MPa, and the maximum contact pressure was 9.6612 MPa. This paper analyzed the optimal shape of dimples by finite element analysis. As a research project, experiments and comparative analysis of micro dimple shapes are needed.

• Journal of Information Processing Systems
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• 제17권6호
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• pp.1044-1056
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• 2021

Globalization has integrated the world through interaction among countries and people with the help of information and telecommunication technology (ICT). The rapid mode of globalization has put a new life in ICT and economic sector. The key focus of this study is to examine the nexus among the globalization, ICT and economic growth. This study uses autoregressive distributed lag model (ARDL), vector error correction model (VECM) and econometric method spanning from 1990 to 2015. The empirical result highlights that the globalization stimulates economic growth of a country. In addition, both the internet penetration and the mobile phone usage contribute to the economic growth. Lastly, this article contributes important policy lessons on strengthening the economy by utilizing ICT with the rapid globalization.

• 한국응용과학기술학회지
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• 제39권5호
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• pp.652-665
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• 2022

본 연구는 새로운 운동문화가 형성되어 가고 있는 과도기적 상황에서, 운동을 겸하고 있는 대학에 재학 중인 골프 종목 체육특기자 학생 선수들을 대상으로 그들이 대학 생활에서 자신이 실제로 해 보거나 겪어 본 과정을 근거이론 방법을 바탕으로 심층적으로 조명하고자 하였다. 이를 위해 충청도에 있는 A 대학 골프학전공에 재학 중인 10명의 특기자 학생을 연구 참여자로 선택하였으며, 이들과의 심층 면담을 통하여 자료를 수집하였다. 자료 분석 과정은 Strauss와 Corbin(1990)이 밝힌 분석 방법에 따라 개념에 대해 결론을 끌어내고 개념 간의 관계를 밝히기 위해 코딩 패러다임을 구성하였고, 결과는 다음과 같다. 첫째, 개방 코딩에서 117개 개념, 16개 하위범주, 10개 상위범주가 도출되었다. 둘째로 인과적 조건은 "비대면 수업의 대학 생활", 맥락적 요소는 "실기 운동", "수업 참여"로 범주화하였으며 중심현상은 "골프 종목 체육특기자 학생으로서의 대학 생활 의미"로 보았다. 중재 조건은 운동과 학업을 함께하는 과정을 살펴본 결과 "관계 형성", "능력향상"으로 정리되었으며 작용/상호작용전략은 "학문 연구", "부정적인 생각"으로 범주화했으며, 마지막으로 결과는 "지난 대학 생활 되돌아보기", "정체성", "미래 설계"로 구성하였다. 이러한 연구 결과를 바탕으로 파악된 체육특기자(골프) 학생들의 운동과 학업을 병행하는 삶의 과정에 대한 모형을 근거 이론적 패러다임의 방법 절차에 따라 범주화하였으며, 골프 종목 체육특기자들은 운동 생활이 학업 생활에 긍정적인 영향을 받게 됨에 따라, 쉼이 없는 대학 생활을 이어나가고 있었으며, 그리고 운동과 학업을 모두 포함할 수 있는 학생 선수의 역량 향상을 위한 정책적 시사점을 제시하였다.

• 대한치과기공학회지
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• 제28권1호
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• pp.121-142
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• 2006

Collecting materials for study on teaching efficiency and satisfaction of clinical training, it changes. Dental technology's educational procedure to many ways of a prospect. In a circumstance that needed higher level of education, this study is aimed on realizing an importance of clinical training through the various materials that previously carried out and offering basic knowledge to take better clinical training for the students. Study results below 1. This Investigation conducted on 123 of sophomores(70.3%) and 52 of juniors(29.7%) who have been taken clinical training, and men's proportion(51.45%)is a bit higher than girls(48.6%). The 64% of respondents taken largest proportion were 20 to 24 years old. As 67.9% of respondents attended daytime school and 30.3% of them attended nighttime one, their school time shows a little difference. In a question about relation ship, one answered "Harmonious" took largest proportion by 72.6% during training, and about the degree of satisfaction of campus life who answered "normal" were the most with 59.4%. 2. About the reason choosing dental technology as a major, 41.1% taken the most answered "due to the specialized job", "Getting job easily" was second with 26.9%, and third was "recommended from around" with 18.3%. 50.3% of the respondents answered "normal" about the Satisfaction of their major, student marked in grade "B" most with 51.4% 3. In a investigation result about clinical training statues and preference, most(72.6%) choose place less than 10 for clinical training, and 60.6% of them resided own home. About their commuting time from home to training place, 44% was under 30min, 40% took time 30-60min. It shows students prefer shotter distance in terms of choosing training place. 4. Each part manager took large proportion as a clinical trainer with 33.7%, Training curriculum reform and developing method were most answer as a improvement measure after completing training with 30%. 5. The average of total score about clinical training was 3.15 of 5. In the detailed question, 'satisfaction of clinical training' got 3.38 as a highest score, the lowest score was 2.86 that is about satisfaction of clinical training period. The average score about efficiency of study was 2.86 and in detailed question, 'a Role model' got 3.26 as a highest score and participation of student got 3.05 as a lowest score. 6. The result of T-test to see the difference of the satisfaction according to the general character and clinic training condition between teaching efficiency is that the degree of satisfaction of clinical training showed statistical significance only in the degree of satisfaction of campus life(p<0.05), and teaching efficiency has a statistical significance with their age, grade, and satisfaction of campus life (p<0.05). 7. The relation between of teaching efficiency of clinical training and satisfaction of clinical training of dental technologic student has a statistical meaning in significance leveler 0.01. Now, therefore we suggest following based on these result. 1. To elevate satisfaction of clinical training, it agentry needs development of consistent clinical training curriculum. 2. To grasp the satisfaction and requirement, in needs to measure anxiousness and satisfactory degree after completing training 3. To train efficiently and evaluate efficiency over the teaching activities, it needs to develop measuring tools for teaching efficiency in terms of teacher's important rules in a clinical training. 4. Strengthen the relations with the study developing and managing curriculum gathering theoretical knowledge and practice. And make an effort to apply to their students. 5. Let the trainee take a class setting a belief, sense of value, function and obtain behavior by making the students comfort over clinical training as increasing teaching efficiency.

• Journal of Nutrition and Health
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• 제42권8호
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• pp.750-758
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• 2009

건강한 성인 남자 48명을 대상으로 각각 당근즙 섭취군과 ${\beta}$-carotene 섭취군, placebo 약 섭취군으로 나누어 8주동안 실시하였으며, 당근즙은 매일 300 mL을 주었고 정제된 항산화 비타민은 당근즙에 함유된 ${\beta}$-carotene과 같은 양을 주어 항산화 영양 상태에 대한 개선 효과를 비교하고자 하였다. 그 결과, 혈장 비타민 C, 비타민 E 및 ${\beta}$-carotene 함량은 당근즙 및 항산화 비타민 섭취 전보다 유의적으로 높게 나타났고, 그 증가 정도가 비슷하게 나타나 식품으로부터 항산화 영양소를 충분히 섭취하는 것이 흡연자의 산화적 손상과 관련된 질병을 예방하는 좋은 방법이 될 수 있을 것이라 사료된다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2010년도 춘계학술대회
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• pp.463-466
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• 2010

본 논문에서는 CCTV를 기반으로 한 화재 감시 시스템 개발을 위하여 기존 센서를 기반으로 하는 화재 탐지 시스템과 영상을 기반으로 하는 시스템들의 장단점을 분석하고 국가적으로 지원하고 있는 U-City, U-Home, U-Campus 등 확산되는 유비쿼터스 환경에 적합한 화재 감시 시스템 모델과 화재를 판별하기위한 기술을 제안한다. 본 연구를 위해 영상을 촬영할 카메라로는 Microsoft LifeCam VX-1000을 사용하였으며, 영상을 촬영하는 코덱으로는 H.264를 사용하였다. 카메라로부터 촬영된 영상 데이터를 가공하여 서버에 전달하는 클라이언트는 Linux OS를 사용하는 ARM9 S3C2440 보드로 제작하였다. 클라이언트와 서버의 영상 데이터 송/수신은 기본적으로 1:1 방식으로 되어있다. 그리하여 카메라의 데이터를 다중으로 수신하기 위한 멀티캐스트 1:N이 가능하게 명세하여, 화재 감시를 위한 다각적 영상 수신 시스템을 설계하였다. 영상 데이터는 RGB 형식을 YUV로 변환하여 전송하며, 화재를 감지하기위한 모션 추출을 위해 Y값을 이용한다. 화재 판별은 붉은 색상을 감지하고 Y값의 움직임을 계산해 화재시 지속적으로 타오르는 불꽃의 모션을 감지하여 판단하는 판별법을 적용한 시스템을 최종적으로 제안한다.