• Title/Summary/Keyword: Camphor

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Chemical Composition and Antibacterial Activity of Essential Oil from Artemisia feddei

  • Cha, Jeong-Dan;Jung, Eun-Kyung;Kil, Bong-Seop;Lee, Kyung-Yeol
    • Journal of Microbiology and Biotechnology
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    • v.17 no.12
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    • pp.2061-2065
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    • 2007
  • The chemical components of the essential oil from Artemisia feddei LEV et VNT. were analyzed using GC-MS. Ninety-nine compounds, accounting for 96.23% of the extracted essential oil, were identified. The main oil compounds were 1,8-cineole (16.86%), chamazulene (9.04%), ${\alpha}$-terpineol (8.18%), ${\alpha}$-phellandrene (5.78%), ${\alpha}$-thujone (5.51%), ${\alpha}$-terpinyl acetate (5.07%), borneol (5.08%), ${\beta}$-caryophyllene (4.71%), camphor (4.04%), and terpinen-4-ol (3.04%). The antimicrobial activity of the essential oil and some of its compounds was tested against 15 different genera of oral bacteria. The essential oil from A. feddei had a considerable inhibitory effect on all the obligate anaerobic bacteria tested (MICs, 0.025 to 0.05 mg/ml; MBCs, 0.025 to 0.1 mg/ml), whereas the major compounds demonstrated different degrees of growth inhibition.

Effects of Drying Conditions on the Antioxidant Activities and Volatile Compounds of Chrysanthemi Flos Flowers

  • Bae, Sung-Mun;Na, Ae-Sil;Seo, Hye-Kyeong;Lee, Seung-Cheol
    • Preventive Nutrition and Food Science
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    • v.14 no.4
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    • pp.329-334
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    • 2009
  • The effects of drying conditions on the antioxidant activities, luteolin, and volatile compounds of Chrysanthemi Flos flowers were evaluated. The flowers were dried with hot-air or far-infrared radiation at 40${^{\circ}C}$, 50${^{\circ}C}$ and 60${^{\circ}C}$, respectively, to reach 22$\pm$1% of moisture content. Each 10 g of the dried flowers were extracted with 100 mL of 95% ethanol. Increasing temperature in hot-air dried (HAD) conditions increased the antioxidant activities of the flower extracts. However, increasing temperature in far-infrared dried (FID) conditions decreased the antioxidant activities of the extracts. Luteolin, one of main flavonoids of Chrysanthemi Flos flowers, was present in the highest content at 60${^{\circ}C}$ FID flowers with a value of 139 $\mu$g/mL. Thirteen volatile compounds including camphor and β-caryophyllene were identified in chromatograms. Higher amount of the volatiles were found at 50${^{\circ}C}$ HAD and 40${^{\circ}C}$ FID. The results indicated that the antioxidant activities and volatile compounds of Chrysanthemi Flos flowers were significantly affected by drying conditions.

Susceptibility of Oral Bacteria to Essential Oil of Artemisia capillaris Thunb.

  • Kim Kyong-Heon;Kim Baek-Cheol;Shin Chol-Gyun;Jeong Seung-Il;Kim Hong-Jun;Ju Young-Sung
    • The Journal of Korean Medicine
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    • v.25 no.4
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    • pp.121-128
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    • 2004
  • Objective : The aim of this work is to investigate the antibacterial activity of the essential oil obtained from Artemisia capillaris (A. capillaris), as the development of microbial resistance to antibiotics make it necessary to constantly look for new and active compounds effective against pathogenic bacteria. Methods : The crushed materials of A. capillaris (1 kg) were subjected to steam distillation for 3 h, using a modified Clevenger type apparatus in order to obtain essential oil. Diethyl ether was the extracting solvent kept at 25°.... The essential oil was analyzed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). The essential oil and the composition were tested for antimicrobial activities against 15 different genera of oral bacteria. Results and Conclusion : The components of the essential oil identified were: β-pinene (9.36%), camphor (3.32%), 1,8­cineole (4.38%), artemisia alcohol (3.32%), β-caryophyllene (11.08%), γ-cadinene (4.23%), and capillene (32.74%). The essential oil of A. capillaris exhibited considerable inhibitory effects against all oral bacteria tested, while their major components demonstrated various degrees of growth inhibition.

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Alternatives to Traditional Mastitis Therapy (전통적 유방염 치료에서 변화)

  • 손봉환
    • Journal of the korean veterinary medical association
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    • v.37 no.1
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    • pp.52-57
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    • 2001
  • 전통적 유방염치료에서 변화는 현대적 우유생산 설비인 덴마크의 연구로부터 나온 결과와 문헌적 고찰을 배경으로 논의된 것이다. 덴마크의 전통적 농장운영제도는 전통적 농부들의 현대화와 1987년에 변화 시킨 정부의 규제법규로 제도화된 것에 의하여 근본적인 형태의 목표로 특성화되어 진다. 모든 질병은 품종, 우사 설비, 사료공급과 경영작전을 통하여 예방되어지는 전통적 농장운영체제에 대한 지침에 의존되어야 하였다. 치료의 농가 선택에 대하여 특별히 관심을 둔 정부규칙은 1. 모든 의학적 예방은 금지된다. 2. 의학적 치료에 뒤 따르는 배출시간은 전통적 농장운영에 비하여 3배가 연장된다. 3. 모든 치료는 수의사에 의하여 수행되어야 한다. 연구는 예방과 치료작전에 초점을 맞춘 전통적 농장운영체제에서 수행한 것이다. 이 과제에서 몇 가지 유방염은 농가자신의 치료로 설명되었으며 그 내용은 다음과 같다. 각 목장에서 유방염은 마싸지 시행과 캠퍼(camphor)또는 페퍼민트오일(pebbermint oil)의 국소응용 그리고 어떤 목장은 동종 요법적 치료(同種 療法的 治療 = Homoeopathic treatment)로 손착유로 하고 농가자신이 치료하였다. 이 결과에서 농부자신의 치료와 수의사 치료가 보여 준 것은 성공 사이에 유의한 차이가 없다. 변화와 전통적 치료에 추가하여 비의학적 치료가 검토되었다. 유방염 건에서 농부 대 수의사 역할은 유방염 문제점이 있는 목장에 근거하면은 똑같다고 검토되었다. 동종 요법적 치료의 문헌연구는 경험을 통하여 수행되어진 것이다. 현 과제는 목장의 치료작전 안에서 종합되고 있는 동종 요법적 치료의 실제적 현상이 설명되고 있다 동종요법은 어떤 건에서 반응이 제안될 수 있는 유방염치료와 관계되는 치료 방법이다. 그러나 덴마크의 경험에서 전통은 유방염 건에서 치료의 선택에 영향이 있을 것이라는 것으로 비교적 제한되어 있다 이 치료에 대한 원리의 배경을 검토하였다.

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Nitrogen Incorporation of Nanostructured Amorphous Carbon Thin Films by Aerosol-Assisted Chemical Vapor Deposition

  • Fadzilah, A.N.;Dayana, K.;Rusop, M.
    • Transactions on Electrical and Electronic Materials
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    • v.14 no.4
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    • pp.165-171
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    • 2013
  • Nanostructured pure a-C and nitrogen doped a-C: N thin films with small particle size of, ~50 nm were obtained by Aerosol-assisted CVD method from the natural precursor camphor oil. Five samples were prepared for the a-C and a-C: N respectively, with the deposition temperatures ranging from $400^{\circ}C$ to $600^{\circ}C$. At high temperature, the AFM clarifies an even smoother image, due to the increase of the energetic carbon ion bombardment at the surface of the thin film. An ohmic contact was acquired from the current-voltage solar simulator characterization. The higher conductivity of a-C: N, of ${\sim}{\times}10^{-2}Scm^{-1}$ is due to the decrease in defects since the spin density gap decrease with the nitrogen addition. Pure a-C exhibit absorption coefficient, ${\alpha}$ of $10^4cm^{-1}$, whereas for a-C:N, ${\alpha}$ is of $10^5cm^{-1}$. The high ${\sigma}$ value of a-C:N is due to the presence of more graphitic component ($sp^2$ carbon bonding) in the carbon films.

Effect of Various Enhancers on Permeation of Scopolamine through Excised Rat Skin (스코폴라민의 흰쥐 피부투과에 대한 투과촉진제들의 영향)

  • Jung, Jae-Young;Kam, Sung-Hoon;Kim, Keon-Nam;Chi, Sang-Cheol;Park, Eun-Seok
    • Journal of Pharmaceutical Investigation
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    • v.33 no.2
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    • pp.141-144
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    • 2003
  • The transdermal therapeutic system (TTS) of scopolamine has various advantages over its oral dosage forms. The ideal scopolamine TTS requires high skin permeation rate in short time after it is applied on the skin. In order to increase the initial skin permeation rate of scopolamine from TTS, various permeation enhancers were employed. Enhancers employed were fatty acids (oleic and linolenic acids), cyclic monoterpenes (menthol, camphor, cineole and limonene) and others (isopropyl myristate, sodium lauryl sulfate and glyceryl monostearate). The concentration of enhancers in the base were fixed to 5% (w/w). While fatty acids had little enhancing effect on the skin permeation of scopolamine, cyclic monoterpenes, isopropyl myristate and sodium lauryl sulfate resulted in $1.5{\sim}2.6-fold$ higher skin permeation rate of the drug compared to the control. However, lag time was not affected by enhancers studied.

Allelopathic Effects of Artemisia lavandulaefolia

  • Kil, B.S.;Han, D.M.;Lee, C.H.;Kim, Y.S.;Yun, K.Y.;Yoo, H.G.
    • The Korean Journal of Ecology
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    • v.23 no.2
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    • pp.149-155
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    • 2000
  • The allelopathic effects of Artemisia lavandulaefolia were studied using several test plants and microbes. Aqueous extracts and volatile compounds of A. lavandulaefolia inhibited seed germination, seedling and root growth of the test species such as Achyranthes japonica. Lactuca sativa, Artemisia princeps var. orientalis. Oenothera odorata, Plantago asiatica. Aster yomena, Elsholtzia ciliata, and Raphanus sativus var. hortensis for. acanthiformis. The root growth of test species was more affected than shoot growth by allelochemicals of A. lavandulaefolia. Essential oil of A. lavandulaefolia had antibacterial and antifungal effects. However, the antimicrobial activity of the essential oil was dependent upon the microbial species and concentrations. Callus growth of Oryza sativa, Brassica campestris subsp. napus var. pekinensis and Achyranthes japonica was sensitive by the essential oil of A. lavandulaefolia. Twenty three chemicals were identified from A. lavandulaefolia essential oil by gas chromatography. Primary allelochemicals among them were 1, 8-cineole, 1-$\alpha$-terpineol, $\alpha$-terpinene. camphor, 2-buten-1-ol and azulene. We concluded that aqueous extract and essential oil of A. lavandulaefolia were responsible for allelopathic effects.

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Phytotoxicity and Volatile Monoterpenes of Leaves from Artemisia capillaris and Artemisia iwayomogi Used as Korean Herbal Injin

  • Yun, Kyeong-Won
    • Journal of Ecology and Environment
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    • v.32 no.1
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    • pp.9-12
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    • 2009
  • Artemisia capillaris and Artemisia iwayomogi are weeds used as medicinal plants in Korea under the name "Injin". I collected leaves of A. capillaris and A. iwayomogi, examined them for phytotoxic effects from volatile substances and determined the composition of monoterpenes in the leaves. The effects of volatile substances from each species on seed germination and radicle elongation in each of the two Artemisia species were assessed. The volatile substances of A. capillaris did not negatively affect the seed germination of A. capillaris, but they did inhibit radicle elongation. Rates of seed germination of A. iwayomogi decreased when the seeds were exposed to high concentration of A. capillaris volatile substances. The inhibition of seed germination and radicle elongation by volatile substances from both Artemisia species was stronger for A. iwayomogi than for A. capillaris. I identified the monoterpenoids from the leaves with a gas chromatograph-mass spectrometer (GC-MS). The main constituents of A. capillaris were acenaphthylene (37.91%), $\beta$-pinene (12.08%), 4-carene (10.61%) and $\gamma$-curcumene (9.92%), while those of A. iwayomogi were germacrene-$\delta$ (32.15%), borneol (21.24%), camphor (20.45%) and trans-caryophyllene (7.75%).

Fluctuation of Solid-Liquid Interface of Faceted Phase and Nonfaceted Phase by Periodic Temperature Variation

  • Oh, Sung-Tag;Kim, Young Do;Song, Young-Jun;Suk, Myung-Jin
    • Korean Journal of Materials Research
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    • v.26 no.11
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    • pp.644-648
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    • 2016
  • In order to examine how the solid-liquid interface responds to temperature variation depending on the materials characteristics, i.e. faceted phase or nonfaceted phase, the moving solid-liquid interface of transparent organic material, as a model substance for metallic materials (pivalic acid, camphene, salol, and camphor-50wt% naphthalene) was observed in-situ. Plots of the interface movement distance against time were obtained. The solid-liquid interface of the nonfaceted phase is atomically rough; it migrates in continuous mode, giving smooth curves of the distance-time plot. This is the case for pivalic acid and camphene. It was expected that the faceted phases would show different types of curves of the distance-time plot because of the atomically smooth solid-liquid interface. However, salol (faceted phase) shows a curve of the distance-time plot as smooth as that of the nonfaceted phases. This indicates that the solid-liquid interface of salol migrates as continuously as that of the nonfaceted phases. This is in contrast with the case of naphthalene, one of the faceted phases, for which the solid-liquid interface migrates in "stop and go" mode, giving a stepwise curve of the distance-time plot.

Composition and Anti-cholinesterase Activity of the Essential Oil Obtained from Korean Elsholtzia ciliata (한국산 향유로부터 얻은 정유의 조성과 콜린에스테라제 억제활성)

  • Song, Byong-Min;Choi, Jae Sue;Park, Hee-Juhn
    • Korean Journal of Pharmacognosy
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    • v.47 no.3
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    • pp.226-231
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    • 2016
  • The present GC-MS analysis elucidated the composition of the essential oil obtained from the herb of Elsholtzia ciliata(Lamiaceae). Overall, the content of monoterpenes was higher than that of sesquiterpenes. Monoterpenes rich in this oil were carvone (peak area, 26.180%), camphor (2.304%), borneol (9.974%), dihydrocarveol (3.296%), ${\alpha}$-citral (=geranial, 4.025%), geranic acid (2.961%), while sesquiterpenes occupying relatively higher percentage were ${\alpha}$-humulene (0.918%), (-)-spathulenol (0.974%), ${\alpha}$-caryophyllene oxide (2.014%), globulol (1.362%), ${\beta}$-caryophyllene oxide (0.750%). The components characterizing this oil were 1-octen-3-ol, acetophenone, and butylated hydroxytoluene. The $IC_{50}$ of this oil on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were $42.37{\mu}g/ml$ and $121.34{\mu}g/ml$, respectively, suggesting that the essential oil of E. ciliata may be active on the memory loss of patients suffering from Alzheimer's disease.