• Biomolecules & Therapeutics
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• 제21권4호
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• pp.251-257
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• 2013

Inflammatory skin diseases such as atopic dermatitis (AD) and rosacea were complicated by barrier abrogation and deficiency in innate immunity. The first defender of epidermal innate immune response is the antimicrobial peptides (AMPs) that exhibit a broad-spectrum antimicrobial activity against multiple pathogens, including Gram-positive and Gram-negative bacteria, viruses, and fungi. The deficiency of these AMPs in the skin of AD fails to protect our body against virulent pathogen infections. In contrast to AD where there is a suppression of AMPs, rosacea is characterized by overexpression of cathelicidin antimicrobial peptide (CAMP), the products of which result in chronic epidermal inflammation. In this regard, AMP generation that is controlled by a key ceramide metabolite S1P-dependent mechanism could be considered as alternate therapeutic approaches to treat these skin disorders, i.e., Increased S1P levels strongly stimulated the CAMP expression which elevated the antimicrobial activity against multiple pathogens resulting the improved AD patient skin.

• 한국식품영양학회지
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• 제14권1호
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• pp.77-81
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• 2001

Inulinase의 생합성 조절 기작을 규명하여 이들의 대량생산을 위한 자료로 활용하고자 Bacillus sphae-ricus 188-1이 생성하는 inulinase의 생합성 조절에 관하여 조사하였다. Inulinase의 생합성은 0.5% inulin을 함유한 생합성 조절용액에서 8시간에 효율적으로 유도되었고 0.5% fructose의 첨가는 inulin에 의한 inulinase의 생합성 유도를 억제시켰으며 fructose를 늦게 첨가할수록 inulinase 생합성 유도가 낮아졌다. CAMP의 첨가는 catabolite repression을 감소시키지 못하였다.

• 한국동물학회지
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• 제37권4호
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• pp.565-572
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• 1994

연두금파리의 유충-번데기-성충의 발생에 따른 cyclic AMP(CAMP)와 ecdysteroids의 농도 및 cyclic AMP-dependent protein kinase(PKA)의 활성도를 High Performance Liquid Chromatography(HPLC)와 Liquid Scintillation Counter(LSC)를 이용하여 측정하고 상관 기능 변화를 조사하였다. CAMP의 농도와 PKA의 활성도는 종령유충 및 성충에서 낮은 갓(0.29 UM/g, 5.52~5.59 unit/mg)을 나타내었고 번데기 0일(0.49 UM/g. 92.22 unit/mg)과 7일(0.50UM/g, 24.45 unit/mg)에서 최고치를 보였으며 번데기 4일에서 최저수준(0.13 $\mu$M/g3.23 unit/mg)을 나타내었다. Ecdysone 농도는 번데기 2일에 최고치(37 84 USlg)를 4일에 최저치(18.46 Ugyg)를 보인 후, 5일에 24.37 1519로 상승하였으며 성충에서는 낮은 값을 나타내었다 그러나 20-hydroxvecdysone 농도는 번데기 4일(23.66 UgyS)과 번데기 6일(14.90 Ugyg)에 최고치를 이루었고, 7일에서 최저치(1.21 USi9)를 나타내었다.

• 한국수학교육학회지시리즈A:수학교육
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• 제51권3호
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• pp.197-210
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• 2012

In this study, we will develop and implement the teaching program of 'Function', on the subject of "Poster-Making utilizing the Graph Art" in the Math Camp for middle-school students. And we will examine the didactical significance through student's activities and products. The teaching program of 'Function' utilizing the Graph Art can be promoted self-directly the understanding of 'Function' concept and the ability for handling 'Function'. In the process of drawing up the graph art, in particular, this program help students to promote the ability for problem-solving and mathematical thinking, and to communicate mathematically and attain the his own level. Ultimately, this program have a positive influence upon cognitive and affective and areas with regard to mathematics.

• 한국산림과학회지
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• 제96권2호
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• pp.203-207
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• 2007

Restorative effect of forest settings is an emerging issue in the field of forestry. It is also the central question facing those currently engaged in the psychotherapeutic interventions is which treatments work. This study was performed to investigate the efficacy of forest experience on alcoholics' depression. Among 531 participants in forest healing camps, 47 alcoholics who participated all three sessions of the camps were selected for this study. Using pre-test and post-test group design with Beck Depression Inventory (BDI), mean changes in alcoholics' depression by completion of the camp was measured. The result of this study indicated that the 3-session of forest camp played significant role in reducing participants depression levels (i.e., positive changes in depression scores).

• 한국산업융합학회 논문집
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• 제20권2호
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• pp.187-194
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• 2017

This study examined the validity and reliability of the thermal safety design, in order to maintain the heat generated from integrated circuit (IC) chips in the converter, condenser, resistor, and transistor (which are considered as heat sources for thermoelectric devices with a printed circuit board) below target levels during the process of developing a control board and a main power board. The study analyzed the heat generation and dissipation characteristics of the entire printed circuit board (PCB) model to examine its thermal safety.

• 한국정밀공학회지
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• 제13권12호
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• pp.54-62
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• 1996

To get the time response characteristics of the hydrostatic transmission, seaborne winch is modelde by using bond graphs. After modeling of its basic elements, it is represented as power flow, and the determination of variable causality. The state equations are derived by using CAMP. As dynamic stabilites and solutions are investigated by perturbation method and direct integration, winch system is stable. Simulations are performed under the conditions of low speed, high speed, and maximum tension. The pressure and flow rate of the hydrostatic transmission have a big overshoot. But when it is comparaed to the empirical data with simulation results, it is similar to each other. When a lead compensator is applied to improve response characteristics of the hydrostatic transmission, rise time and overshoot of the system are improved.

• 한국환경교육학회:학술대회논문집
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• 한국환경교육학회 2001년도 후반기 정기 학술발표대회 발표논문집 PROCEEDINGS
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• pp.29-32
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• 2001

• 건축사
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• 통권580호
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• pp.22-35
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• 2017

• 한국환경교육학회:학술대회논문집
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• 한국환경교육학회 2004년도 전반기 정기 학술발표대회
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• pp.85-88
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• 2004