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Explorations of Evidence-based Policymaking (EBPM) for Reconciling Science and Policy: Developing a Conceptual Framework for Improved Understanding of EBPM in Wind Industry Emergence

  • Lee, Kyounglim;Platts, Jim;Minshall, Tim
    • STI Policy Review
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    • v.6 no.2
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    • pp.146-173
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    • 2015
  • This study explores how to reconcile science and policy in the wind energy sector by providing a conceptual framework for better understanding evidence-based policymaking (EBPM). Regarding this framework, the core issue is to discover how knowledge is formed over time, and which factors affect this knowledge formation. Comparative cases of wind industry emergence in Spain and Britain are examined. This analysis shows that knowledge formation initially starts in the scientific arena in parallel with its formation in the practical, and is followed by political knowledge formation near the beginning of commercial projects. Regarding knowledge formation, three more comparisons are made between wind industry emergence in Spain and Britain: the different approaches to R&D projects, the different adoptions of supporting measures, and the different ways of coping with public opposition. The factors affecting the comparisons are mainly perceptions of energy supply, nuclear power, environment and science and technology. Communication and unfamiliarity are likely to affect the comparisons in EBPM.

Computational load reduction by avoiding the recalculation of angular redundancy in computer-generated holograms

  • Jia, Jia;Chen, Jhensi;Chu, Daping
    • ETRI Journal
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    • v.41 no.1
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    • pp.52-60
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    • 2019
  • A fast hologram calculation approach is proposed to reduce computational load by avoiding the recalculation of redundancy information. In the proposed method, the hologram is divided into several sub-holograms that record and reconstruct different views of 3D objects. The sub-hologram is generated from its adjacent calculated sub-holograms by only adding the holograms of difference images between an adjacent pair of views. The repetitive information of two adjacent views is called angular redundancy. Therefore, avoiding the recalculation of this angular redundancy can considerably reduce the computational load. Experimental results confirm that the proposed method can reduce the computational time for the statue head, rabbits, and car to 4.73%, 6.67%, and 10.4%, respectively, for uniform intensity, and to 56.34%, 57.9%, and 66.24%, respectively, for 256 levels intensity, when compared to conventional methods.

Layer-by-layer nitrogenation of microcrystalline silicon for TFT applications

  • Bu, I.;Milne, W.I.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2004.08a
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    • pp.405-407
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    • 2004
  • We have optimized the low temperature growth of microcrystalline silicon at 80$^{\circ}C$. This material has been used to fabricate bottom gate ${\mu}c$-Si:H TFTs by using a layer-by-layer nitrogenation process. By using this process the amorphous incubation layer can be converted into silicon nitride and leads to an increase in field effect mobility of the TFT

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Two newly recorded genera Gongylidioides Oi, 1960 and Mermessus O.P.-Cambridge, 1899 with descriptions of Gongylidioides kaihotsui Saito and Ono, 2001 and Mermessus naniwaensis (Oi, 1960) (Araneae: Linyphiidae) from Korea

  • Kim, Seung Tae;Lee, Sue Yeon;Yoo, Jung-Sun
    • Journal of Species Research
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    • v.5 no.2
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    • pp.201-205
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    • 2016
  • Gongylidioides kaihotsui Saito and Ono, 2001 and Mermessus naniwaensis (Oi, 1960) of Linyphiidae are described from Korea with taxonomic illustrations. The genera Gongylidioides Oi, 1960 and Mermessus O.P.-Cambridge, 1899 are newly recorded genera to Korean spider fauna.

Does surgical procedure type impact postoperative pain and recovery in deep inferior epigastric artery perforator flap breast reconstruction?

  • Azizi, Alexander A.;Mohan, Anita T.;Tomouk, Taj;Brickley, Elizabeth B.;Malata, Charles M.
    • Archives of Plastic Surgery
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    • v.47 no.4
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    • pp.324-332
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    • 2020
  • Background The deep inferior epigastric artery perforator (DIEP) flap is the commonest flap used for breast reconstruction after mastectomy. It is performed as a unilateral (based on one [unipedicled] or two [bipedicled] vascular pedicles) or bilateral procedure following unilateral or bilateral mastectomies. No previous studies have comprehensively analyzed analgesia requirements and hospital stay of these three forms of surgical reconstruction. Methods A 7-year retrospective cohort study (2008-2015) of a single-surgeon's DIEP-patients was conducted. Patient-reported pain scores, patient-controlled morphine requirements and recovery times were compared using non-parametric statistics and multivariable regression. Results The study included 135 participants: unilateral unipedicled (n=84), unilateral bipedicled (n=24) and bilateral unipedicled (n=27). Univariate comparison of the three DIEP types showed a significant difference in 12-hour postoperative morphine requirements (P=0.020); bipedicled unilateral patients used significantly less morphine than unipedicled (unilateral) patients at 12 (P=0.005), 24 (P=0.020), and 48 (P=0.046) hours. Multivariable regression comparing these two groups revealed that both reconstruction type and smoking status were significant predictors for 12-hour postoperative morphine usage (P=0.038 and P=0.049, respectively), but only smoking, remained significant at 24 (P=0.010) and 48 (P=0.010) hours. Bilateral reconstruction patients' mean hospital stay was 2 days longer than either unilateral reconstruction (P<0.001). Conclusions Although all three forms of DIEP flap breast reconstruction had similar postoperative pain measures, a novel finding of our study was that bipedicled DIEP flap harvest might be associated with lower early postoperative morphine requirements. Bilateral and bipedicled procedures in appropriate patients might therefore be undertaken without significantly increased pain/morbidity compared to unilateral unipedicled reconstructions.

Fibrin affects short-term in vitro human mesenchymal stromal cell responses to magneto-active fibre networks

  • Spear, Rose L.;Symeonidou, Antonia;Skepper, Jeremy N.;Brooks, Roger A.;Markaki, Athina E.
    • Biomaterials and Biomechanics in Bioengineering
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    • v.2 no.3
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    • pp.143-157
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    • 2015
  • Successful integration of cementless femoral stems using porous surfaces relies on effective periimplant bone healing to secure the bone-implant interface. The initial stages of the healing process involve protein adsorption, fibrin clot formation and cell osteoconduction onto the implant surface. Modelling this process in vitro, the current work considered the effect of fibrin deposition on the responses of human mesenchymal stromal cells cultured on ferritic fibre networks intended for magneto-mechanical actuation of in-growing bone tissue. The underlying hypothesis for the study was that fibrin deposition would support early stromal cell attachment and physiological functions within the optimal regions for strain transmission to the cells in the fibre networks. Highly porous fibre networks composed of 444 ferritic stainless steel were selected due to their ability to support human osteoblasts and mesenchymal stromal cells without inducing untoward inflammatory responses in vitro. Cell attachment, proliferation, metabolic activity, differentiation and penetration into the ferritic fibre networks were examined for one week. For all fibrin-containing samples, cells were observed on and between the metal fibres, supported by the deposited fibrin, while cells on fibrin-free fibre networks (control surface) attached only onto fibre surfaces and junctions. Initial cell attachment, measured by analysis of deoxyribonucleic acid, increased significantly with increasing fibrinogen concentration within the physiological range. Despite higher cell numbers on fibrin-containing samples, similar metabolic activities to control surfaces were observed, which significantly increased for all samples over the duration of the study. It is concluded that fibrin deposition can support the early attachment of viable mesenchymal stromal cells within the inter-fibre spaces of fibre networks intended for magneto-mechanical strain transduction to in-growing cells.

Carbon nanotubes for Field Emission Displays.

  • Milne, W.I.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2004.08a
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    • pp.919-922
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    • 2004
  • The Field Emission Display is potentially an excellent display with high brightness and low power consumption with wide viewing angle but more work is still needed in order to identify the ideal electron emitter for such displays. This paper will review the work that we have carried out in Cambridge aver the past couple of years on optimisation of Carbon nanotubes for use as the cold cathode emitters that are possible candidates as the electron sources in second generation FEDs.

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Juxtacrine regulation of cellular senescence

  • Narita, Masashi
    • BMB Reports
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    • v.52 no.1
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    • pp.3-4
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    • 2019
  • Cellular senescence is defined as a state of stable cell cycle exit in response to various stimuli, which include both cytotoxic stress and physiological cues. In addition to the core non-proliferative aspect, senescence is associated with diverse functionalities, which contribute to the role of senescence in a wide range of pathological and physiological processes. Such functionality is often mediated by the capability of senescent cells to communicate with their surroundings. Emerging evidence suggests that senescence is not a single entity, but a dynamic and heterogeneous collective phenotype. Understanding the diverse nature of senescence should provide insights into the complexity of tissue homeostasis and its disruption, such as in aging and tumorigenesis.

The Effects of Open Innovation on Firm Performance: A Capacity Approach

  • Ahn, Joon Mo;Mortara, Letizia;Minshall, Tim
    • STI Policy Review
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    • v.4 no.1
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    • pp.74-93
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    • 2013
  • Although open innovation (OI) has been an important research theme for over a decade, its theoretical framework has been relatively under-researched. As OI involves a wide range of innovation activities, a firm's capacities in the use of the various firm resources play a critical role in OI implementation. However, it is unclear how they affect firms' performances for little is known of OI capacities. Based on a theoretical framework derived from the literature, this study looks into the relationships between six OI capacities (inventive, absorptive, transformative, connective, innovative, and desorptive) and financial performance using the Korean Innovation Survey (KIS) 2008 data. The research model was tested using structural equation modelling (SEM) while potential differences in capacities between different firm groups were also investigated. The results indicate that 1) OI capacities are significantly associated with firms' financial performance; 2) capacities are highly correlated with one another; and 3) some capacities are differently configured between different types of firms. Findings suggest that policy makers should pay more attention to helping firms enhance OI capacities and attempt to develop relevant policies in order to complement inadequate capacities.