• Journal of Ginseng Research
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• 제42권3호
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• pp.389-399
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• 2018

Background: The antioxidant effects of Panax ginseng have been reported in several articles; however, little is known about the antimelanogenesis effect, skin-protective effect, and cellular mechanism of Panax ginseng, especially of P. ginseng calyx. To understand how an ethanol extract of P. ginseng berry calyx (Pg-C-EE) exerts skin-protective effects, we studied its activities in activated melanocytes and reactive oxygen species (ROS)-induced keratinocytes. Methods: To confirm the antimelanogenesis effect of Pg-C-EE, we analyzed melanin synthesis and secretion and messenger RNA and protein expression levels of related genes. Ultraviolet B (UVB) and hydrogen peroxide ($H_2O_2$) were used to induce cell damage by ROS generation. To examine whether this damage is inhibited by Pg-C-EE, we performed cell viability assays and gene expression and transcriptional activation analyses. Results: Pg-C-EE inhibited melanin synthesis and secretion by blocking activator protein 1 regulatory enzymes such as p38, extracellular signal-regulated kinases (ERKs), and cyclic adenosine mono-phosphate response element-binding protein. Pg-C-EE also suppressed ROS generation induced by $H_2O_2$ and UVB. Treatment with Pg-C-EE decreased the expression of matrix metalloproteinases, mitogen-activated protein kinases, and hyaluronidases and increased the cell survival rate. Conclusion: These results suggest that Pg-C-EE may have antimelanogenesis properties and skin-protective properties through regulation of activator protein 1 and cyclic adenosine monophosphate response element-binding protein signaling. Pg-C-EE may be used as a skin-improving agent, with moisture retention and whitening effects.

• 동의신경정신과학회지
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• 제27권2호
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• pp.67-76
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• 2016

Objectives The purpose of this study is to report that a patient with obsessive-compulsive disorder (OCD) significantly responds to Korean medical treatments and psychotherapy.Methods We treated the patient with Korean medical treatments (acupuncture and herbal medication) and Melonis Calyx Vomiting Therapy. We also used psychotherapy including Li-Gyeung-Byun-Qi therapy. The patient was diagnosed by DSM-IV diagnostic criteria for OCD. We used Obsessive-Compulsive Inventory-Revised-Korean (OCI-R-K), Visual Analogue Scale (VAS), Beck’s Depression Inventory (BDI), and Beck’s Anxiety Inventory (BAI) to evaluate the patient.Results OCI-R-K score was decreased from 39 points to 9 points. BDI score was decreased from 14 points to 6 points. BAI score was decreased from 25 points to 13 points.Conclusions This study suggests that Korean medical treatment is an effective way to treat patients who suffer from OCD.

• Mycobiology
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• 제29권2호
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• pp.110-112
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• 2001

A black scab was observed on strawberry(Fragaria ananassa) in plastic film houses around Jinju area during the winter of 2000. The disease started from leaves then moved to calyx and runner. At the beginning, the infected area started with small dark brown spots then gradually expanded. The pathogenic fungus was purely isolated from the diseased leaves, calyx and runner. The fungus was inoculated to test Koch's postulates and proved to be the causal agent of the disease. The isolated fungus grew readily on potato dextrose agar, forming dark green to dark gray colonies. The optimum temperature for mycelial growth was about $25^{\circ}C$. The diameter of growing hyphae was $3.8{\sim}5.6{\mu}m$. Conidia were ellipsoidal, ovoid or subspherical, mostly one-celled but occasionally septate. The size of conidia were $4.1{\sim}11.7{\times}3.8{\sim}5.3$ 1-cell, $9.3{\sim}18.8{\times}4.0{\sim}7.4{\mu}m$ 2-cell and formed in long branched chains on the erected conidiophores which were dark brown and variable in length between $28.8{\sim}236.2{\times}3.0{\sim}6.2{\mu}m$ in size. The fungus was identified as Cladosporium herbarum on the basis of its morphological characteristics. The black scab disease of strawberry caused by C. herbarum has not been reported in Korea previously.

• 한국임상수의학회지
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• 제21권1호
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• pp.66-71
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• 2004

2 Cases of nephrotomy for removal of calculi in dog were referred to veterinary teaching hospital of Konkuk University. In case 1, a 5 year-old, castrated male Yorkshire Terrier dog was referred because of intermittent hematuria, pain in urination for one month. Hematologic and chemical examination showed mild increased BUN and CPK. Radiographic findings revealed radiopaque materials in the urinary bladder, urethra, and left kidney. Retrograde hydropropulsion was performed to move the calculi into the bladder, and cystotomy was done to remove calculi. Nephrotomy was performed to removal of the calculi from the left renal pelvis and calyx. After operation renal function were recovered and preserved. In case 2, a 5 year-old, neutral female Schnauzer dog was referred because of persistant vomiting, anorexia, and celialgia for 20 days. Hematologic and chemical examination showed stress leucogram, moderate azotemia, hypercalcemia, hyperphosphatemia, and increased ALP. Radiographic findings revealed enlargement of the left kidney and radiopaque materials in the both of the kidneys. On excretory urography, left kidney was no pyelogram. On ultrasonography, renal tissue was very thin and distended renal pelvis appeared. Nephrectomy of nonfunctional left kidney and nephrotomy for removal of calculi from the right renal pelvis and calyx were done. One week after operation, renal and hepatic functions were recovered. So, in cases of renal calculi, it is necessary that renal calculi are extracted actively as far as the patient's body condition endurable.

• 한방안이비인후피부과학회지
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• 제28권4호
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• pp.186-195
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• 2015

Objectives : The purpose of this study is to report the efficacy of using oriental medical treatment withMelonis Calyxvomiting therapy for sudden sensorineural hearing loss(SSNHL).Methods : We experienced one case of SSNHL treated with oriental medical treatment(acupuncture, herbal medicine) andMelonis Calyxvomiting therapy(MCVT). MCVT is a traditional treatment, which induces vomiting by eatingMelonis Calyxpowder with water. To evaluate the results of this treatment, we measured the hearing recovery, decrease of tinnitus and vertigo. The degree of hearing improvement was evaluated by Siegel's Criteria. Decrease of tinnitus and vertigo was assessed by Visual Analogue Scale(VAS).Results : The pure tone 5 frequency average improved by 39㏈(marked recovery, from 64㏈ to 25㏈). VAS of tinnitus decreased from 10 to 1, and vertigo decreased from 4 to 0.Conclusions : This study suggests that using MCVT with oriental medical treatment is effective on SSNHL.

• 식물분류학회지
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• 제38권3호
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• pp.251-270
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• 2008

한국산 족도리풀속 식물을 분류학적으로 재검토하여 7종으로 정리하였다. 이 중 한국 특산종은 Asarum glabrata, A. koreanum, A. maculatum, A. patens, A. versicolor 의 5종이었다. 족도리풀속 식물을 구분하는 유용한 형질은 악통과 악편의 형태, 크기 및 색깔이었으며, 잎 표면의 흰색 반점 유무, 잎의 크기, 색깔 및 두께, 모용의 존재, 주두 돌기의 형태 및 크기, 그리고 악편의 두께 등도 유용한 형질임이 확인되었다. 정확한 종동정을 위해 종검색표와 각 분류군의 기재 및 화부구조의 도해를 제시하였다.

• Food Science and Biotechnology
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• 제16권1호
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• pp.123-126
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• 2007

The quality of Yukbo strawberry (Fragaria ananassa Duch.) fruit declines rapidly after harvest. Therefore, we examined the effects of nitric oxide (NO) on its respiration rate, quality, and shelf life. Strawberries were fumigated for 5 hr at 0, 50, 100, 200, or $500\;{\mu}L/L$ NO atmosphers, followed by a hold at $18^{\circ}C$ in air. Treatment with NO delayed the onset of ethylene production ad reduced respiration, which at $18^{\circ}C$ resulted I a maintained quality and prolonged shelf life. The NO-treated strawberries were also firmer and had a lower incidence of disease than the untreated fruit. The effect of NO on fruit quality was dose-dependent. Strawberries that were treated with low and high concentrations of 50 and $500\;{\mu}L/L$ No, respectively, had severe disease incidence and were of poor quality. Treating with NO at a concentration of $200\;{\mu}L/L$ appeared to slow down the ripening and senescence of fruit stored at $18^{\circ}C$. Calyx browning, respiration, and rot development progressed more quickly in strawberries treated with $500\;{\mu}L/L$ NO compared to those treated with $200\;{\mu}L/L$ No.

• 동의신경정신과학회지
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• 제30권2호
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• pp.107-118
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• 2019

Objectives: The objective of this study is to report the effectiveness of Korean medicine therapy on Psychologic tremor patients with MCVT. Methods: Korean medicine therapy including MCVT, herb, acupuncture, and psychotherapy are applied to psychologic tremor patients. Vas and AIMS are used as assessment tools to evaluate the effects of therapy. MCVT is a traditional Korean medicine technique usually for chronic diseases. Similarly, autogenic training by J.H.Schultz and Giungoroen-therapy was conducted as psychotherapy. Results: In case 1, the patient lost all symptoms from vas10 to vas0, while in case 2, symptoms of the patient decreased from vas10 to vas3. Additionally, there was a significant decrease in the AIMS measurement score for both patients. Psychotherapy helped to reduce depression and anxiety. Conclusions: Psychologic tremor can be treated using Korean traditional medicine such as MCVT, Sosiho-tang and psychotherapy.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.26-26
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• 2020

Daphne L. (Thymelaceae) comprises about 95 species distributing worldwide from N Africa, N India, SE Asia to E Asia and the coast of the Mediterranean of Europe. In Korea, five species of this genus have been described. In this study, we included four species (D. genkwa, D. pseudomezereum, D. kiusiana, D. jejudoensis) from Korea, excluding cultivated D. odora. The morphological characters through local surveys and the re-classification of the specimens collected in the Korea National Herbarium (KH) were carried out and distribution maps for each taxon were also prepared. The major characters include habit, trichomes in winter bud, leaf, and twig, phyllotaxis, inflorescence, size of calyx lobe and trichomes in the calyx tube, etc. The distribution map showed that D. genkwa is mainly distributed in the coastal area of Hwanghaenam-do, Pyeongannam-do, Jeollabuk-do and Jeollanam-do, whereas D. pseudomezereum is distributed in the limestone zone of Gangwon-do, Jeollabuk-do, and Gyeongsangbuk-do. Similarly, D. kiusiana is mostly found in Jeollanam-do, Gyeongsangnam-do, and Jeju-do. In addition, D. jejudoensis is known to be distributed in forests of Murueng, Andeok, and Seonheul-ri in Jeju-do, but recently, new habitat is discovered in the island forest areas of Jeollanam-do. However, some of these individuals showed the characteristics of D. kiusiana, thus before come to any conclusion detailed taxonomic review of D. jejudoensis and D. kiusiana is required.

• 원예과학기술지
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• 제33권3호
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• pp.420-428
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• 2015

상업적으로 재배되고 있는 대부분의 포도 꽃은 완전화로서 개개의 꽃들이 모여 화서를 이룬다. 포도 꽃은 5개의 수술, 1개의 암술, 5개의 꽃잎이 융합된 구조인 화관, 그리고 융합된 형태의 꽃받침을 가지며 화방 내 각각의 꽃은 수정하여 과립으로 발달한다. 포도에서는 과립 형성이나 과립비대, 당도의 축적에 대한 연구는 많이 수행된 반면 배우체의 형태 형성, 꽃 기관의 구조, 그리고 꽃 발달과 같은 꽃의 형태적 연구는 거의 이루어지지 않고 있다. 본 연구에서는 '캠벨얼리'와 '탐나라'의 두 품종에서 꽃의 구조와 발달에 따른 특징들을 조사하였다. 포도 꽃의 발달 단계 결정은 애기장대에서 소포자의 형성부터 수 배우체의 발달 시기인 꽃발달 9단계부터 13단계로만 한정하였다. 포도 꽃 발달 9단계에서는 4분포자가 나타났고 꽃 발달 10에서 11단계 동안에는 단세포성 소포자에서부터 중기 2세포성 화분으로 발달하였다. 개화 직전의 꽃 발달 12단계 말에는 성숙한 3세포성화분으로 발달하였다. 꽃 발달 13단계에는 화관이 탈락하고 개화가 일어났다. 꽃 발달 9단계부터 12단계까지 꽃받침 길이는 거의 변하지 않았지만 화관의 길이는 계속 증가했다. 두 포도 품종에서 '꽃받침 길이에 대한 화관 길이의 비율'의 평균은 꽃 발달 9단계에서는 2.0, 꽃 발달 10단계에서는 3.0, 꽃 발달 11단계에서는 4.5, 꽃 발달 12단계에서는 6.5로 나타났으며, '꽃받침 길이에 대한 화관 길이의 비율'을 사용하여 꽃 발달 단계를 판별할 수 있었다. 본 연구 결과로 '캠벨얼리'와 '탐나라'에서 꽃 발달 단계를 정확하게 추정하는 형태적 지표가 개발되었다. 이를 이용하면 두 품종에서 소포자 배양 시기의 판정이나 '탐나라'에서 무핵과 유도를 위한 지베렐린 처리 시기의 판정 등에 유용하게 활용될 수 있을 것이다.