• 대한수의학회지
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• 제47권2호
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• pp.233-239
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• 2007

This study was carried out to evaluate the effects of Dochetang for the treatment of chronic diarrhea in a 4 months-old-female Korean native calf. The calf was presented to the Wow Animal Clinic, Iksan with the history of chronic diarrhea for several weeks. The feces test did not reveal the presence of the parasites or microbes causing diarrhea in calf. The blood test was also negative to the virus that causes of diarrhea in calf. Adminstration of parenteral antibiotics resulted in improvement of the condition temporarily but diarrhea was recurred again after 2-3 weeks. Then the calf was treated with Dochetang administered orally once a day in an empty stomach for 15 days. Feces was significantly reduced in moisture on 7 days after initial treatment. On 9 days after initial treatment, the calf had normal appetite and defecation in physiological conditions. Blood samples were collected before administration and on 1, 2 and 3 weeks after initial administration of Dochetang for hematology and biochemistry. A significantly differences were observed in the white blood cell (WBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), albumin (ALB), glutamic pyrubic transaminase (GPT), inorganic phosphorus (IP) and magnesium (Mg), while no significant differences were seen in the red blood cell (RBC), hemoglobin (Hb), hematocrit (HCT), platelet (PLT), glucose (Glu), total protein (T-pro), glutamic oxaloacetic transaminase (GOT), blood urea nitrogen (BUN) and creatine (CRE). This study suggests that Dochetang administration can be a successful alternative therapeutic agent in instead of antibiotics for the treatment of chronic diarrhea in calves.

• 한국동물위생학회지
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• 제43권3호
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• pp.161-165
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• 2020

In order to effective treats a sick calf, it is necessary to obtain accurate information about the patient's condition. However, the standard references for Korean cattle claves are not well known. Therefore, this study aims to present useful clinical values by analyzing normal blood and diarrhea blood of Hanwoo calf. Recently, with the advent of a portable blood analyzer, it is possible to immediately analyze the patient's condition and severity in the field, not in the laboratory, and to calculate a suitable dosage for supporting fluid therapy. Therefore, in this study, the distribution of red blood cells (RBC) and white blood cells (WBC) were analyzed in normal and diarrhea Hanwoo calves. As a result, Hematocrit (HCT) levels increase significantly between 1 and 20 days in diarrhea positive calves. Changes in leukocyte composition had similar growth patterns in normal and diarrhea calves. As it grew, the proportion of neutrophils decreased and lymphocytes increased. However, the number of WBCs increased from 1 to 10 and 21 to 30 days in diarrhea positive calves, which is closely related to the increase in neutrophils. Therefore, those data can be used for diagnosis and treatment of diarrhea calf.

• Journal of Animal Science and Technology
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• 제63권4호
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• pp.864-871
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• 2021

Infectious calf diarrhea is one of the most significant diseases of neonatal calves. This study is conducted to identify the prevalence of pathogens in calf diarrhea for 2 years. A total of 544 feces samples from Korean native beef calves were obtained to investigate selected seven pathogens causing calf diarrhea: bovine rotavirus, bovine coronavirus, Cryptosporidium parvum, bovine viral diarrhea virus, Eimeria species, Escherichia coli K99, and Salmonella species. The presence of diarrhea, the number and species of detected pathogens, and the calves' ages were analyzed using various statistical methods depending on the case. Of the 544 calves, 340 calves (62.5%) had normal feces and 204 calves (37.5%) had diarrhea. The presence of pathogens was significantly associated with diarrhea (p < 0.01) and fecal scores and the number of detected pathogens showed a significant linear trend (p < 0.001). Of the 7 target pathogens, 6 were detected in samples, but only C. parvum (p = 0.001) and bovine rotavirus (p < 0.001) were found at significantly higher rates in diarrheic calves than in non-diarrheic calves. Only Eimeria spp. showed a significant linear trend between the detection rate of the pathogen and the age groups (p < 0.05).

• Asian-Australasian Journal of Animal Sciences
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• 제24권5호
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• pp.643-649
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• 2011

The objective of this study was to determine the effect of feeding direct-fed microbials (DFM) on the growth performance and prophylaxis of calf diarrhea during the pre-weaning period as an alternative to antibiotics. A multi-species DFM was formulated including three lactic acid bacteria (Lactobacillus salivarius Ls29, Pediococcus acidilactia Pa175, and L. plantarum Lp177), three Bacillus strains (B. subtilis T4, B. polymyxa T1 and SM2), one yeast, Saccharomyces boulardii, and a nonpathogenic E. coli Nissle 1917. Lactic acid bacteria and Bacillus strains were selected based on the antibacterial activity against various animal pathogens, especially pathogenic E. coli using agar diffusion methods in vitro. Test and control groups were fed milk replacer and calf starter supplemented with DFM ($10^9$ cfu each of eight species/d/head, n = 29) or with antibiotics (0.1% neomycin sulfate in milk replacer and Colistin 0.08% and Oxyneo 110/110 0.1% in calf starter, n = 15), respectively. Overall fecal score and the incidence rate of diarrhea were reduced in the DFM group compared to the antibiotics one. About 40% of calves in antibiotic group suffered from diarrhea while in DFM group only 14% showed diarrhea. There was no difference in the average daily gain and feed efficiency of two groups. The hematological levels of calves were all within the normal range with no significant difference. In conclusion, the feeding of multispecies DFM during the pre-weaning period could reduce calf diarrhea and there was no difference in the growth performance between the groups, thus showing the potential as an alternative to antibiotics.

• 한국임상수의학회지
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• 제26권6호
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• pp.578-581
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• 2009

25일령의 한우송아지가 10일 간의 호흡기질환과 출혈성 설사의 병역을 나타내다가 폐사하였다. 이 송아지는 다른 송아지들과 비교해보았을 때 극도로 위축되어 있었다. 꼬리와 회음부의 분변 흔적은 만성설사가 지속되었음을 말해주었다. 부검시 다양한 기관(조직)에서 반상출혈이 관찰되었다. 역전사 중합효소연쇄반응에 의하여 소 바이러스성 설사병 바이러스가 진단되었다. 이 증례는 계통발생분석에서 BVDV-2a 그룹에 속하는데, 이것은 고병원성인 미국 균주890 (U18059)과 유사하다. 본 증례는 BVDV-2가 한국에서 유행하고 있다는 증거를 제공한다. 이를 통해 우리는 BVDV-2의 발생을 재확인하였다.

• 한국엔터테인먼트산업학회논문지
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• 제13권8호
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• pp.335-343
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• 2019

건강한 삶은 인간이 추구하는 행복의 필수불가결한 요소이다. 식생활은 그 기반을 제공하는 것이며 가축의 건강은 사람의 건강에 직접적인 영향을 준다. 가축 질병을 정확하게 예측하고 관리하는 것은 지속가능한 가축의 생산을 보장하고 인간의 건강을 유지하는 데 기여한다. 사람의 경우 만병의 근원이 감기라면, 송아지의 경우 모든 질병의 원인을 제공하는 것은 설사병이다. 따라서 송아지의 설사병을 스마트 센서로 생체 데이터를 추출하고, 수집된 생체 데이터는 전처리 후에 의미 있는 정보로 사용한다. 축사의 환경 정보와 송아지 객체의 생화학·면역·감염원인체의 측정 정보를 온톨로지로 구축한다. 온톨로지는 논리적 추론 절차를 거쳐 송아지의 설사병을 예측할 수 있는 지식 베이스로 구축하였다. 송아지의 질병명, 원인, 발생 시기, 증상에 대해서 지식 기반으로 설사병을 예측한다. 가축의 일부 중에서 송아지를 모델한 지식 기반의 가축 원격 진료 질병 예측은 상위 온톨로지와 예측에 관한 도메인 온톨로지로 표현하여 그 결과로 치료, 예방법을 제시할 수 있다.

• 한국임상수의학회지
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• 제24권4호
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• pp.529-536
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• 2007

The purpose of this study was to elucidate the effect of Oldenlandiae herba and Houttuyniae cordata on calf diarrhea in farms. We examined the antibacterial and antiviral effect of Oldenlandiae herba and Houttuyniae cordata extracts in vitro. And we divided diarrheal calves into three roups in farm; Oldenlandiae herba administration group(10 calves), Oldenlandiae herba and Houttuyniae cordata administration group(10 calves) and control group(7 calves). We estimated the therapeutic effect of the calf diarrhea by using clinical signs, CBC, AST, BUN, creatinine, and measurement of lymphocyte distribution in whole blood. Oldenlandiae herba and Houttuyniae cordata extracts by ethanol(98%) had antibacterial and antiviral effect. In the condition of diarrhea, the fecal condition of Oldenlandiae herba and Houttuyniae cordata group was relieved more than that of others group during experimental period. PCV and fibrinogen concentrations were high in control group. AST and BUN were within normal range in all groups. Administration of Oldenlandiae herba and Houttuyniae cordata was not toxic to the liver and kidney. And Oldenlandiae herba and Houttuyniae cordata extracts also affected the lymphocytes distribution in blood. From these results, we suggested that administration of Oldenlandiae herba and Houttuyniae cordata should be effective on the dairy calf diarrhea in farms.

• 대한수의학회지
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• 제60권3호
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• pp.183-186
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• 2020

This paper describes the development of neurological signs of two prematurely born calves four days after birth. The pathological examination results indicated fibrinopurulent polyserositis, including meningoencephalitis with suppurative bronchopneumonia. Bovine viral diarrhea virus subtype 2a was detected in most of the internal organs, and the bacterial colonies cultured from the samples were identified as Klebsiella (K.) pneumoniae. Molecular analysis via multilocus sequence typing identified a different K. pneumoniae isolate in each calf-type 14 in calf A and type 65 in calf B. This is the first report identifying K. pneumoniae sequence types 14 and 65 in cattle.

• 현장농수산연구지
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• 제10권1호
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• pp.201-205
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• 2008

For the prevention of Hanwoo calf diarrhea, the floor in a cattle shed was flamed using liquefied petroleum gas (LPG) in an attempt to substitute for the chemical disinfection method. Before flaming, litter on the floor was removed and cleaned. Outbreak rate of diarrhea in calves vaccinated with ScourGuard 3K^® was decreased from 70% to 30% and the effect of the flame disinfection lasted for three to four months.

• 한국동물위생학회지
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• 제45권3호
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• pp.201-209
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• 2022

An epidemiological study was conducted to investigate five diarrhea-causing pathogens (coronavirus, rotavirus, E. coli, Cryptosporidium, Giardia) using a rapid diagnostic kit in Hanwoo calves with diarrhea in Chungcheongbuk-do, Korea, from 2018 to 2021. A total of 22,417 fecal samples were collected from calves under 1 year of age; of those, 13,518 (60.3%) were positive for five bovine diarrhea antigens. The antigen positivity rates for rotavirus, coronavirus, E. coli, Giardia, and Cryptosporidium were 34.5%, 11.0%, 8.2%, 4.7%, and 2.0%, respectively. The prevalence of the five pathogens in calves was statistically higher in autumn and winter. The highest prevalence of the pathogens was observed in the under 1 month age group, and the incidence of diarrhea decreased with age. Rotavirus was a major pathogen in calves under 1 month of age, whereas the prevalence of E. coli increased with age. This study provides epidemiological evidence of the prevalence of calf diarrheal pathogens in Chungcheongbuk-do, Korea, which will facilitate early diagnosis and development of measures against calf diarrhea.