• 한국방사선학회논문지
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• 제15권5호
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• pp.603-612
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• 2021

컴퓨터단층촬영의 관상동맥 칼슘(coronary artery calcium, CAC) 점수에서 Advanced Modeled Iterative Reconstruction (ADMIRE)의 영향을 평가하였다. 89명의 환자를 대상으로 128 slice dual-source CT로 관상동맥 칼슘 영상(348개의 칼슘, 6개 그룹, 총 2088개의 칼슘)을 획득하였다. Filtered back projection(FBP)과 ADMIRE(1-5)로 재구성된 이미지로부터 Volume score, Agatston score를 측정하였다. FBP와 ADMIRE Strength(1-5) 간의 차이는 Kruskal-Wallis 검정을 통해 확인하고, 사후분석은 FBP를 기준으로 Mann-Whitney U 검정을 하였다. Volume score와 Agatston score 모두 FBP와 ADMIRE(1-5)간에 통계적으로 유의한 차이가 있었습니다(P=0.015, P=0.0.38). 추가로 사후분석 한 결과 Volume score는 FBP를 기준으로 ADMIRE 4(Z=-2.359, P=0.018)에서 9.5 %, ADMIRE 5(Z=-3.113, P=0.002)에서 13.2 % 감소하는 것으로 나타났다. Agatston score는 FBP를 기준으로 ADMIRE 4(Z=-2.051, P=0.040)에서 10.4 %, ADMIRE 5(Z=-2.718, P=0.007)에서 14.0 % 감소하는 것으로 나타났다. 높은 ADMIRE strength는 칼슘 면적의 감소로 인하여 Volume score, Agatston score에 영향을 준다. 또한, Maximum HU의 감소로 인한 Density factor 변화는 Agatston score 계산에 영향을 줄 수 있다.

• 한국방사선학회논문지
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• 제17권7호
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• pp.1033-1039
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• 2023

폐 스크리닝 검사로 이용되고 있는 저선량 흉부 CT는 Scan 범위 내에 관상동맥 석회화에 대한 정보도 함께 포함하고 있어 이를 이용한 관상동맥 석회화 판별의 유용성을 알아보고자 한다. 저선량 흉부 CT 검사와 관상동맥 석회화 점수(CACS) 검사를 같은 날 시행 받은 자들을 대상으로 하였다. 관상동맥 석회화 점수 검사 결과를 Coronary artery calcium score categories and risks 분류법을 참고하여 4개 그룹(Low: 1〈CACS〈10, Mild: 10〈CACS〈100, Moderate: 100〈CACS〈400, High: 400〈CACS)으로 각각 30명을 선정한 후 관상동맥 석회화 수치 측정 업무에 종사하고 있는 경력 15년차 이상 5명의 방사선사가 저선량 흉부 CT 영상에서 관상동맥 석회화 유무를 후향적으로 분석하였다. 저선량 흉부 CT 영상에서 5명의 관찰자가 통일되게 판독한 결과가 관상동맥 석회화점수 CT 검사 결과와 일치한 경우는 Low 그룹: 56%, Mild 그룹: 96.6%, Moderate 그룹: 100%, High 그룹: 100%로 나타났다. Low 그룹에서 5명의 관찰자 모두가 석회화를 관찰한 것은 30건 중 17건이었으며, 5명이 모두 판별 불가로 결정한 경우 7건이었다. 무증상 성인을 대상으로 저선량 흉부 CT 검사에서 석회화 점수가 15 이상인 경우에는 관상동맥 석회화를 100% 관찰할 수 있었다. 판별이 가능한 최소 석회화 수치는 1로, 피검자의 체형이 작거나 심장의 움직임이 최소가 되는 시점에서 스캔이 이루어지는 경우 매우 작은 석회화까지도 판별할 수 있다는 것을 알 수 있었다.

• Journal of Nutrition and Health
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• 제31권1호
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• pp.102-107
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• 1998

This study was conducted to investigate the relationship of serum calcium and magnesium levels to depression and anxiety symptoms in 80 homemarker. Fasting blood samples were collected and serum calcium and magnesium concentrations were measured. At the same time, psychological conditions of subjects were estimated by questionnaire. As the result of psychological test, eighty homemarkers were divided into two groups according to psychologicaltest scores. The subjects in one group got high pssycholgoical test scores as high score group (HSG) and the others got low physchological test scores as low score group(LSG). Serum calcium and magnesium concentrations were significantly(p<0.05) lower in HSG than in HSG than in LSG. Many a subject who belonged to HSG appeared to have depression and anxiety symptoms. Drepression and anxiety scores of the subjects with calcium supplementation were significantly (p<0.05) lower than those without calcium supplementation . After calcium supplementation, depressiion and anxiety scores were significantly (p<0.05) decreased in HSG and serum calcium and magnesium concentrations in HSG were significantly increased to normal ranges . This results suggested that psychological conditions of homemarkers might be affected by serum calcium and magnesium levels.

• Korean Journal of Radiology
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• 제22권11호
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• pp.1764-1776
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• 2021

Objective: This study aimed to validate a deep learning-based fully automatic calcium scoring (coronary artery calcium [CAC]_auto) system using previously published cardiac computed tomography (CT) cohort data with the manually segmented coronary calcium scoring (CAC_hand) system as the reference standard. Materials and Methods: We developed the CAC_auto system using 100 co-registered, non-enhanced and contrast-enhanced CT scans. For the validation of the CAC_auto system, three previously published CT cohorts (n = 2985) were chosen to represent different clinical scenarios (i.e., 2647 asymptomatic, 220 symptomatic, 118 valve disease) and four CT models. The performance of the CAC_auto system in detecting coronary calcium was determined. The reliability of the system in measuring the Agatston score as compared with CAC_hand was also evaluated per vessel and per patient using intraclass correlation coefficients (ICCs) and Bland-Altman analysis. The agreement between CAC_auto and CAC_hand based on the cardiovascular risk stratification categories (Agatston score: 0, 1-10, 11-100, 101-400, > 400) was evaluated. Results: In 2985 patients, 6218 coronary calcium lesions were identified using CAC_hand. The per-lesion sensitivity and false-positive rate of the CAC_auto system in detecting coronary calcium were 93.3% (5800 of 6218) and 0.11 false-positive lesions per patient, respectively. The CAC_auto system, in measuring the Agatston score, yielded ICCs of 0.99 for all the vessels (left main 0.91, left anterior descending 0.99, left circumflex 0.96, right coronary 0.99). The limits of agreement between CAC_auto and CAC_hand were 1.6 ± 52.2. The linearly weighted kappa value for the Agatston score categorization was 0.94. The main causes of false-positive results were image noise (29.1%, 97/333 lesions), aortic wall calcification (25.5%, 85/333 lesions), and pericardial calcification (24.3%, 81/333 lesions). Conclusion: The atlas-based CAC_auto empowered by deep learning provided accurate calcium score measurement as compared with manual method and risk category classification, which could potentially streamline CAC imaging workflows.

• 한국농촌생활과학회지
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• 제7권1호
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• pp.39-50
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• 1996

This study was carried out to investigate nutrients intake and dietary environments of rural and asylum elderly in partial Kyunggi area. Results were as followes: (1) Educational level of 2 groups of rural and asylum elderly was only literacy, And rural elderly worked more than the aged of asylum. (2) The nutrients intake of rural elderly was very small quantity: Energy intake was 62% of RDA, that of protein 59%, calcium 56%, and iron 72% only. This nutrients intake state was lower than that of asylum elderly. (3) Health score CMI was selected 31 cases of items for aged. Ryal elderly received 11.7/31, but the scores of asylum elderly were 7.1 only. It means that asylum elderly felt more healthy than rural. (4) The correlation Serum TG was significant with protein fat and calcium, but serum calcium was not significant with intake of calcium. The nutrients intake was correlated with CMI score and dietary habit score.

• The Korean journal of internal medicine
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• 제39권2호
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• pp.283-294
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• 2024

Background/Aims: Epicardial adipose tissue (EAT) shares pathophysiological properties with other visceral fats and potentially triggers local inflammation. However, the association of EAT with cardiovascular disease (CVD) is still debatable. The study aimed to observe the changes and associations in EAT and risk factors over time, as well as to investigate whether EAT was associated with CVD. Methods: A total of 762 participants from Seoul National University Hospital (SNUH) and SNUH Gangnam Center were included in this study. EAT was measured using coronary computed tomography angiography. Results: Baseline EAT level was positively associated with body mass index (BMI), calcium score, atherosclerotic cardiovascular disease (ASCVD) 10-year risk score, glucose, triglycerides (TG)/high-density lipoprotein (HDL), but not with total cholesterol, low-density lipoprotein (LDL). At follow-up, EAT levels increased in all groups, with low EAT groups demonstrating a significant increase in EAT per year. Change in EAT was associated with a change in BMI, TG/HDL, and glucose, while changes in LDL, calcium score, and ASCVD 10-year risk score were not associated. Although calcium score and ASCVD 10-year risk score were associated with CVD events, baseline information of EAT, baseline EAT/body surface area, or EAT change was not available. Conclusions: Metabolic risks, e.g., BMI, TG/HDL, and glucose, were associated with EAT change per year, whereas classical CVD risks, e.g., LDL, calcium score, and ASCVD 10-year risk score, were not. The actual CVD event was not associated with EAT volume, warranting future studies combining qualitative assessments with quantitative ones.

• 대한지역사회영양학회지
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• 제1권1호
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• pp.71-78
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• 1996

This study was conducted to compare the dietary factors which influence on the bone status of 28 women in urban and 30 women in rural area. Urinary excretion of hydroxyproline(Hpr) and Calcium(Ca) were measured as biological markers of bone resorption. Mean daily intake levels of total protein, animal protein, total calcium, calcium, calcium from milk and milk products, animal calcium, Ca / P ratio by 24 hr recall method were significantly higher in urban women. However, mean daily sodium(Na) intake levels were not significantly different between two groups. Ca Index score and Na Index score by food frequency methods were also significantly higher in urban than in rural subjects. While urinary Ca excretion elves of two groups were similar, Na excretion levels were significantly higher in rural women. Mean urniary levels of Ca / creatinine(cr) and Hpr / cr as bone status index were within normal range and not significantly different between two groups. However, prevalence of poor bone status as assessed by hydroxyproline was higher in rural women. Na Index, urinary Ca excretion and Ca / cr ratio were significantly correlated with bone status(Hpr / cr) in urban women, while only age was related to bone status in rural women. These demonstrated that high Na intake results in increased urinary excretion of Na and Ca and could cause bone resorption. Multiple regression analysis indicated that Na Index score and age have greater effect than other variables in urban women and only age has greater effect in rural women.

• Nutrition Research and Practice
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• 제6권6호
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• pp.527-533
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• 2012

It is thought that calcium (Ca) and magnesium (Mg) may be related to mental disorders such as depression; however, there have been few studies investigating the association between Ca and Mg nutrition status with depression in middle-aged female adults. Study subjects in this study included 105 women between the ages of 41 and 57 years. The subjects were divided into three groups according to the Zung Self-rating Depression Scale (SDS) score: Group I (SDS score < 33 percentile; n = 32), Group II (33 percentile ${\leq}$ SDS score < 67 percentile; n = 37), and Group III (67 percentile ${\leq}$ SDS score; n = 36). Anthropometric measurements, dietary intake survey using 3-day dietary records, SDS questionnaire and measurement of serum Ca and Mg were obtained and analyzed. No differences were observed in Ca, plant Ca, and Mg intake among the three groups. However, animal Ca intake by Group III was 141.3 mg, which was significantly lower than 207.6 mg by Group I and 198.3 mg by Group II (P = 0.0345). There were no significant differences in serum levels of Ca, and Mg among the three groups. Correlation analysis indicated that the SDS score had negative correlations with Ca intake (r = -0.2927, P<0.01) and animal Ca (r = -0.3411, P<0.001) after adjusting for age, menopause and energy intake. In conclusion, dietary Ca and animal Ca had negative associations with SDS score among middle-aged Korean female adults. Additional analysis of factors related to the association of calcium and magnesium nutritional status and depression is necessary.

• 성인간호학회지
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• 제19권5호
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• pp.80-91
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• 2007

Purposes: To identify the predictors of calcium intake behavior and examine the relationships among bone mineral density, osteoporosis knowledge, osteoporosis health belief, osteoporosis self efficacy and calcium intake behavior of postmenopausal osteoporosis patients. Methods: The subjects consisted of 94 patients. The measurement tools were osteoporosis knowledge test, osteoporosis health belief scale, osteoporosis self-efficacy and calcium intake frequency questionnaire. The data were analyzed using the SPSS WIN 11.0 program. Results: The bone mineral density of the lumbar were $0.75g/cm^2$, T-score -2.67 and the femur neck were $0.67g/cm^2$, T-score -2.30. There was statistically a significant correlation between calcium intake behavior and health motivation (r=0.449, p=0.000) among the osteoporosis health belief. In hierarchial multiple regression analysis, current spouse(12.8%) and health motivation(19.9%) of the osteoporosis health belief explained the 32.7% of variance in calcium intake behavior. Conclusion: Nursing intervention should be developed for increasing the calcium intake behavior through promoting health motivation for the postmenopausal osteoporosis women having no spouse currently.

• 지역사회간호학회지
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• 제16권1호
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• pp.77-85
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• 2005

Purpose: This study was to determine the effects of calcium intake on bone mineral density (BMD) in pre and post menopause women and to provide basic data for enhancing bone health of middle aged women. Methods: A total of 700 middle-aged women living in Seoul and Geonggi Province were interviewed during the period from June 2003 through January 2004 to investigate their social. demographic and physiological characteristics, health and daily activity performance, and their dietary patterns, and bone mineral density was measured. The survey of dietary intake was 24 hour recalls, and the individual calcium intake was calculated using food frequency. Data of 618 subjects was used for the analysis. Of the calcium intake levels, BMD values of the subjects of 20% of high level. 60% of middle level and 20% of low level were analyzed and compared. Results: The level of calcium intake according to general characteristics of the subjects was significantly related to age (p=0.001), education levels (p=.003) and marital status (p=.001). The BMD of the lumbar vertebrae and femur of the subjects taking a high level of calcium showed significantly higher than that of the subjects taking a middle level and low level of calcium. Femoral T-score was also significantly higher in subjects taking a high level of calcium than that of those taking a middle level and lower levels of calcium. Lumber spine T-score was higher in the high level group than that of the middle level group. Conclusion: The study revealed that women taking a high level of calcium had better bone health. Therefore. calcium intake is extremely important in daily dietary intake so that the intake of calcium-rich foods is highly recommended.