• The Korean Journal of Food And Nutrition
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• v.33 no.3
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• pp.223-236
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• 2020

In this study, a safety evaluation was conducted to confirm if the Enterococcus faecium CKDB003 strain obtained by selection from a mixed fermentation of fruit and milk is suitable for use as a probiotic. The MIC value for the 10 antibiotics specified in the EFSA guidance was below the acceptable cut-off value. The antibiotic resistance genes aac(6')-li, eatAv, and msr(C) exist by whole genome sequencing, but are in the chromosome and not in the plasmid, thus confirming that there is no possibility of transmission to other microorganisms. It was confirmed that cytolysin (cylA, cylB, cylI, cylL-l, cylL-s, cylM, cylR1, cylR2), aggregation substance (asa1, asp1), collagen adhesion (ace), enterococcal surface protein (esp), endocarditis antigen (efaA), hyaluronidase (hyl) and gelatinase (gelE) were not present in the genome by examining the genes of factors related to virulence. Also, the biochemical analysis showed no toxic enzyme activities, and no virulence genes were detected by the PCR method. Thus, the E. faecium CKDB003 strain can be safely used as a health functional food probiotic, based on the results of the safety assessment.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.1
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• pp.159-163
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• 2000

In this study, It obtained that how myopitic astigmatism eyes appear in highschool students. The results were as follows. 1. In test, myopitic astigmatism eyes of men students are measured 60% in ratio and women students are measured are 57% in ratio. 2. In $-1.00{\geq}$cyl>0.00 Dptr, myopitic astigmatism eyes are measured 82% in ratio and in $-1.50{\geq}$cyl>-1.00 that is measured 12% in ratio. 3. In -2.00>cyl, myopitic astigmatism eyes are measured 6% in ratio. 4. In the kind of astigmatism, The direct astigmatism axis is 81 % in ratio and each of the indirect astigmatism axis and the oblique astigmatism is 5%, 14% in ratio.

• BMB Reports
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• v.28 no.3
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• pp.227-231
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• 1995

In order to figure out the relationships between structural features and biological activity of the host-specific HC-toxin in maize, structurally related cyclic tetrapeptides, chlamydocin and CYL-2 were isolated, and their biological activities in maize were examined. Biological activities of preparations were determined by root growth inhibition and electrolyte leakage bioassays. Chlamydocin and CYL-2 showed toxicities to maize. However, the toxicities of these compounds were non-specific. Thus, the precise peptide ring structure of HC-toxin apparently does not play an important role in toxicity, while resistance of maize to HC-toxin is based on a precise ring conformation.

• CDE review
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• v.3 no.1
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• pp.50-51
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• 1997

CYL/HEAD제작에 있어서 DIGITAL MOCK-UP의 효과는 다음과 같다. 1. PATTERN에서 가상 몰드를 만들어 몰드의 장, 탈착성을 검토할 수 있고 각 몰드 및 전체중량을 산출할 수 있기 때문에 최적의 PARTING을 할 수 있다. 2. 가상 몰드의 조립에 의해서 가상 주물형을 만들 수 있기 때문에 생산하기 전에 실물의 내, 외부의 정확한 형상을 알 수가 있다. 즉 주물공정상 외형부분과 CORE 부분의 형상을 따로 만들기 때문에 형상을 잘못 만들었든가 몰드 조립을 잘못 했든가 하는 등의 이유로 간혹 두께가 맞지 않은 경우가 있는데 SECTION 확인에 의해서 외형부분과 CORE 가장자리에 두께가 제대로 되어 있는지 알 수가 있으므로 오류를 줄일 수 있다.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.1
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• pp.58-62
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• 2022

Objectives : The aim of this study is to report the effect of long-term acupuncture on a amblyopia derived from astigmatism. Methods : A 39-month-old-female child presented with decreased visual acuity with simple astigmatism and amblyopia in the left eye. She took long-term acupuncture treatment once or twice a week for almost four years. And the autorefractor follow-up were conducted per every 6 months. Results : At the initial visit, naked eye visual acuity was 0.1/0.7(OD/OS), Sph. +0.00D, Cyl. -2.25D, AXIS 148° in the right eye, and Sph. +0.00D, Cyl. -0.25D, AXIS 49° in the left eye. After acupuncture treatment for about 4 years without correctional glasses, the visual acuity of the right eye was 1.0, the right eye had Sph. +0.00D, Cyl -0.50D, AXIS 146°, and the left eye had Sph. -0.25D, Cyl -0.50D, AXIS 154°. The visual acuity was maintained until 1 year follow up as 0.9/1.0(OD/OS). Conclusions : This study shows the possibility of using acupuncture treatment for amblyopia derived from astigmatism.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.1
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• pp.69-80
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• 2009

Purpose: We investigated validity of a monitor-based computer eye test program, Test Chart 2000 Pro (developed by Thomson Software Solutions, UK). Methods: We chose ten common eye tests of the Test Chart 2000 Pro and Korean Standard Eye Test, applying them to same subject groups each by each, followed by comparison and analyses of agreement degree of the results. Results: Among the ten eye tests, Snellen Chart, Cross-cyl target, Duochrome test, Fan and Block test, and Random dot stereograms showed statistically significant agreement between both the Korean standard eye test method and Test Chart 2000 Pro. On the other hand, some disagreements were found between the two eye test methods in LogMAR Chart, Single Letter Chart, Phoria Test, Fixation Disparity Test, and Worth 4 Dot Test. Conclusions: Comparing to the Korean Standard Eye Test that consists of Han eye chart and Phoroptor, validity of the Test Chart 2000 Pro is not so high. Further improvements of the Test Chart 2000 Pro in accuracy are required.

• Journal of Korean Ophthalmic Optics Society
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• v.3 no.1
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• pp.103-113
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• 1998

Until now, the study of eye refractive error examination for high school students are a few report that in Korea. In particular, there is few report about the visual power for same group during several years. We compared the study of refractive error done this year with that reported three years ago at the same high school. From the these data, the distribution of ammetropia was investigated. The study of refractive error for high school students was also compared with those reported before for the Adults and the middle school student. When the visual power is refered to spherical equivalent, the 36% of the whole students examined above had emmetropia and the other part of them fumed out to be ammetropia which is classify to 60.6% belonged to myopia and 4.4% belonged to hyperpia. The ratio of myopia for this year students is increased in comparision with the students in 1995. The ratio of emmetropia for this year students is 7.4% higher, and the ratio of myopia for this year students is 4% higher, but the ratio of hyperopia is very lower than that for the adults in 1997. In the kind of refractive error, it is classified that a simple myopia is shown to highest ratio as a 28.6% of 1212 eyes examined, a compound myopic astigmatism to the next high ratio as a 22.4%, a simple myopic astigmatism as 14.4%, a simple hyperopic astigmatism as 3.1%, a mixed astigmatism as a 1.7%, a simple astigmatism as 1.2%, a compound hyperopic astigmatism as 1.2%, respectively. The percentage of an astigmatism is a 76.7% of total eyes examined if Cyl-0.25 Dptr is included to an astigmatism. On the other hand, The percentage of an astigmatism is a 45.6% of total eyes examined if Cyl-0.25 Dptr is excluded to an astigmatism. In the kind of astigmatism, the number of students had an astigmatism with the rule is about 4.5 times than that of astigmatism against the rule. From the result of comparision the right eye with the left eye, the right eye of the students had more a myopic refractive error than the left eye, which is same as adults' case, there is no difference in a refractive error between the boy students and the girl students.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.1
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• pp.131-138
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• 2000

We compared the study of refractive error of the eyes done in 1998 with that reported three years ago at any high school in the north Kyungki. From the these data, the distribution of ammetropia was investigated. The study of refractive error for high school students was also compared with those reported before for the Adults and the middle school student. When the refractive error is refered to spherical equivalent, the 40.6% of the whole students examined above had emmetropia and the other part of them(59.4%) turned out to be ammetropia which is classified to 46.4% belonged to myopia and 13.0% belonged to hyperpia. The ratio of emmetropia for the students in 1998 is 4.4% lower, and the ratio of hyperopia is 4.3% lower, but the ratio of myopia for the students in 1998 is 8.7% higher than that for the student in 1995. In the kind of refracive error, it is classified that a simple myopia is shown to highest ratio as a 23.6% of 6143 eyes examined, a compound myopic astigmatism to the next high ratio as a 17.4%, a simple myopic astigmatism as 10.9%, a simple hyperopic astigmatism as 9.8%, a simple astigmatism as 7.1%, a compound hyperopic astigmatism as 2.2%, a mixed astigmatism as a 1.8%, respectively. The percentage of an astigmatism is a 69.6% of total eyes examined if Cyl-0.25 Dptr is included to an astigmatism. On the other hand. The percentage of an astigmatism is a 45.0% of total eyes examined if Cyl-0.25 Dptr is excluded to an astigmatism. In the kind of astigmatism, the number of students had an astigmatism with the rule is about 5.6 times than that of astigmatism against the rule. From the result of comparison the right eye with the left eye, the right eye of the students had more a myopic refractive error than the left eye, which is same as adults' case.

• KSBB Journal
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• v.28 no.1
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• pp.54-59
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• 2013

Three isolates, E. faecium P1, P2 and P3, from intestinal drugs of three phamaceutical companies, four clinical vancomycin resistant isolates, E. faecium V1, V2, V3 and E. faecalis V4, and three isolates, E. faecalis DW01, DW07 and DW14, from infant feces were tested for the presence of virulence genes, ace, agg, esp, efaA, gelE, sprE, vanA and vanB as well as fsrABC, regulatory genes of gelE and sprE, cylMBA, cytolysin activation genes and cpd, cob and ccf, pheromone genes by PCR and for their phenotype activities such as protease, biofilm formation, cell clumping and hemolysis. The genes encoding cell surface adherence proteins, ace, agg, esp and efaA, were predominantly amplified from the vancomycin resistant strain V4 and the fecal isolates DW01, DW07 and DW14. Both protease and biofilm formation activity were detected only from E. faecalis V4 from which the PCR products of gelE and spreE as well as fsrABC were amplified. The pheromone genes were amplified from the V4, DW01, DW07 and DW14 strains and these strains showed clumping activity. Biofilm formation was observed from the strains DW01, DW07 and DW14, all of which produced PCR products of pheromone, and V4 as well. Whole cytolysin regulator genes were amplified from DW01, DW07 and DW14 and ${\beta}$-hemolysis activity was detected from these strains. Any virulence genes or activities except the pheomone gene ccf were not detected from the pharmaceutical isolates, E. faecium P1, P2 and P3.

• The Korean Journal of Pesticide Science
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• v.12 no.2
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• pp.103-110
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• 2008

To develop the third generation herbicidal cyclic imide (Cyl) derivatives, the new 1-(4-chloro-2-fluoro-5-propargyloxyphenyl)-3-thiourea derivatives were synthesized and measured their herbicidal activities ($pI_{50}$) in vivo (preemergence) against rice plant (Orysa Sativa) and barnyard grass (Echinochlor crus-galli). The synthetic yields (%) of aryl derivatives (21-40) in general was higher than that of alkyl derivatives (1-20). In case of alkyl derivatives, the synthetic yield depended on the structural forms of alkyl amine groups. From the results of correlation analysis between herbicidal activities and substituents, the compound 8 and 24 showed the highest herbicidal activity against the shoot and root of barnyard grass. Especially, the compounds 11 and 6 showed the selective herbicidal activities between rice plant and barnyard grass.