• Title/Summary/Keyword: CTS

Search Result 377, Processing Time 0.025 seconds

Accuracy of FDG-PET/CT for Detection of Incidental Pre-Malignant and Malignant Colonic Lesions - Correlation with Colonoscopic and Histopathologic Findings

  • Kunawudhi, Anchisa;Wong, Alexandra K;Alkasab, Tarik K;Mahmood, Umar
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.8
    • /
    • pp.4143-4147
    • /
    • 2016
  • Purpose: We evaluated all PET/CTs acquired for patients without a primary diagnosis of colorectal cancer, and compared results for those who had subsequent colonoscopy within 6 months, to assess the accuracy of FDG PET/CT for detection of incidental pre-malignant polyps and malignant colon cancers. Materials and Methods: Medical records of 9,545 patients who underwent F-18 FDG PET/CT studies over 3.5 years were retrospectively reviewed. Due to pre-existing diagnosis of colorectal cancer, 818 patients were excluded. Of the remainder, 157 patients had colonoscopy within 6 months (79 males; mean age 61). We divided the colon into 4 regions and compared PET/CT results for each region with colonoscopy and histopathologic findings. True positive lesions included colorectal cancer, villous adenoma, tubulovillous adenoma, tubular adenoma and serrated hyperplastic polyp/hyperplastic polyposis. Results: Of 157 patients, 44 had incidental colonic uptake on PET/CT (28%). Of those, 25 had true positive (TP) uptake, yielding a 48% positive predictive value (PPV); 9% (4/44) were adenocarcinoma. There were 23 false positive (FP) lesions of which 4 were hyperplastic polyp, one was juvenile polyp and 7 were explained by diverticulitis. Fifty eight patients had false negative PET scans but colonoscopy revealed true pre-malignant and malignant pathology, yielding 23% sensitivity. The specificity, negiative predictive value (NPV) and accuracy were 96%, 90% and 87%, respectively. The average SUVmax values of TP, FP and FN lesions were 7.25, 6.11 and 2.76, respectively. There were no significant difference between SUVmax of TP lesions and FP lesions (p>0.95) but significantly higher than in FN lesions (p<0.001). The average size (by histopathology and colonoscopy) of TP lesions was 18.1 mm, statistically different from that of FN lesions which was 5.9 mm (p<0.001). Fifty-one percent of FN lesions were smaller than 5 mm (29/57) and 88% smaller than 10 mm (50/57). Conclusions: The high positive predictive value of incidental focal colonic FDG uptake of 48% for colonic neoplasia suggests that colonoscopy follow-up is warranted with this finding. We observed a low sensitivity of standardly acquired FDG-PET/CT for detecting small polyps, especially those less than 5 mm. Clinician and radiologists should be aware of the high PPV of focal colonic uptake reflecting pre-malignant and malignant lesions, and the need for appropriate follow up.

Luminescence characterization of $EU^{3+}$ and $Bi^{3+}$ co-doped in ${Y_2}{SiO_5}$ red emitting phosphor by solid state reaction method (고상 반응법으로 합성한 ${Y_2}{SiO_5}:\;EU^{3+}$, $Bi^{3+}$ 적색 형광체의 발광 특성)

  • Moon, J.W.;Song, Y.H.;Park, W.J.;Yoon, D.H.
    • Journal of the Korean Crystal Growth and Crystal Technology
    • /
    • v.19 no.1
    • /
    • pp.15-18
    • /
    • 2009
  • To enhance near UV-visible absorption region and to applied phosphor convert-white LEOs (PC-WLEDs), a red phosphor composed of ${Y_2}{SiO_5}:\;EU^{3+}$, $Bi^{3+}$ compounds was prepared by the conventional solid-state reaction. The photoluminescence (PL) shown that samples were excited by near UV light 395 nm for measurement of PL spectra. Emission spectra of samples have shown red emissions at 612 nm ($^5D_0{\to}^7F_2$). The enhanced near $UV{\sim}$ visible excitation spectrum with a broad band centered at 258 nm and 282 nm originated in the transitions toward the charge transfer state (CTS) due to the $Eu^{3+}-Bi^{3+}-O^{2-}$ interaction. The other excitation band at $350\;nm{\sim}480\;nm$, corresponding to the transitions $^7F_0{\to}^5L_9$ (364 nm), $^7F_0{\to}^5G_3$ (381 nm), $^7F_0{\to}^5L_6$ (395 nm), $^7F_0{\to}^5D_3$, (415 nm) and $^7F_0{\to}^5D_2$ (466 nm), occurred due to enhanced the f-f transition increasing $Bi^{3+}$ and $Eu^{3+}$ ions. The PL intensity increased with increased as concentration of $Bi^{3+}$ and the emission intensity becomes with a maximum at 0.125 mol.

Effect of Interference in CSMA/CA Based MAC Protocol for Underwater Network (CSMA/CA 기반 수중 통신망에서 간섭의 영향 연구)

  • Song, Min-je;Cho, Ho-shin;Jang, Youn-seon
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.40 no.8
    • /
    • pp.1631-1636
    • /
    • 2015
  • With the advance of wireless communication technology in terrestrial area, underwater communication is also evolving very fast from a simple point-to-point transmission to an elaborate networked communications. Underwater acoustic channel has quite different features comparing with the terrestrial radio channel in terms of propagation delay, Doppler shift, multipath, and path loss. Thus, existing technologies developed for terrestrial communication might not work properly in underwater channel. Especially medium access control (MAC) protocols which highly depend on propagation phenomenon should be newly designed for underwater network. CSMA/CA has drawn lots of attention as a candidate of underwater MAC protocol, since it is able to resolve a packet collision and the hidden node problem. However, a received signal could be degraded by the interferences from the nodes locating outside the receiver's propagation radius. In this paper, we study the effects of interference on the CSMA/CA based underwater network. We derived the SNR with the interference using the sonar equation and analyzed the degradation of the RTS/CTS effects. These results are compared with the terrestrial results to understand the differences. Finally we summarized the design considerations in CSMA/CA based underwater network.

AQ-NAV: Reinforced Learning Based Channel Access Method Using Distance Estimation in Underwater Communication (AQ-NAV: 수중통신에서 거리 추정을 이용한 강화 학습 기반 채널 접속 기법)

  • Park, Seok-Hyeon;Shin, Kyungseop;Jo, Ohyun
    • Journal of Convergence for Information Technology
    • /
    • v.10 no.7
    • /
    • pp.33-40
    • /
    • 2020
  • This work tackles the problem of conventional reinforcement learning scheme which has a relatively long training time to reduce energy consumption in underwater network. The enhanced scheme adjusts the learning range of reinforcement learning based on distance estimation. It can be reduce the scope of learning. To take account the fact that the distance estimation may not be accurate due to the underwater wireless network characteristics. this research added noise in consideration of the underwater environment. In simulation result, the proposed AQ-NAV scheme has completed learning much faster than existing method. AQ-NAV can finish the training process within less than 40 episodes. But the existing method requires more than 120 episodes. The result show that learning is possible with fewer attempts than the previous one. If AQ-NAV will be applied in Underwater Networks, It will affect energy efficiency. and It will be expected to relieved existing problem and increase network efficiency.

Economic Injury Levels and Control Thresholds of pyrausta panopealis Walker (Lepidoptera: Pyralidae) on Perilla under Green-house (시설잎들깨 들깨잎말이명나방(Pyrausta panopealis)의 경제적 피해수준 및 요방제 수준)

  • Choi, Yong-Seok;Park, Deok-Gi;Yun, Yeo-Uk;Hwang, In-Su;Shin, Sun-Mee;Choe, Kwang-Ryul
    • Korean journal of applied entomology
    • /
    • v.47 no.2
    • /
    • pp.149-154
    • /
    • 2008
  • Pyrausta panopealis is the major pest in green perilla. The larva weaves a web on the shoot of green perilla and damages. In case of extreme, The larva cuts the main branch of green perilla and the leaf of green perilla isn't harvested anymore. A field study was conducted to estimate economic injury levels (EILs) and control thresholds (CTs) for P. panopealis injuring green perilla in green-houses. Different densities of P. panopealis ranged from 1 to 20 crops (2 units per crop) per 100 crops on 13. June, early inoculation. The number of injured leaf and the rate of injured crop were increased by 23. June, on the other hand were decreased after that day. Also, the amount of yield sow the same result above. The economic loss time calculated by the ratio of cost managing this moth to market price (C/V) (C: cost managing a moth, V: Market price) was 4.0%. The economic injury level was 5.1 larval per 100 crops. The control thresholds calculated by 80% level of economic injury level was 4.1 larval per 100 crops.

Development of 4D CT Data Generation Program based on CAD Models through the Convergence of Biomedical Engineering (CAD 모델 기반의 4D CT 데이터 제작 의용공학 융합 프로그램 개발)

  • Seo, Jeong Min;Han, Min Cheol;Lee, Hyun Su;Lee, Se Hyung;Kim, Chan Hyeong
    • Journal of the Korea Convergence Society
    • /
    • v.8 no.4
    • /
    • pp.131-137
    • /
    • 2017
  • In the present study, we developed the 4D CT data generation program from CAD-based models. To evaluate the developed program, a CAD-based respiratory motion phantom was designed using CAD software, and converted into 4D CT dataset, which include 10 phases of 3D CTs. The generated 4D CT dataset was evaluated its effectiveness and accuracy through the implementation in radiation therapy planning system (RTPS). Consequently, the results show that the generated 4D CT dataset can be successfully implemented in RTPS, and targets in all phases of 4D CT dataset were moved well according to the user parameters (10 mm) with its stationarily volume (8.8 cc). The developed program, unlike real 4D CT scanner, due to the its ability to make a gold-standard dataset without any artifacts constructed by modality's movements, we believe that this program will be used when the motion effect is important, such as 4D radiation treatment planning and 4D radiation imaging.

The Relationships between Covert Narcissism and Dating Violence among College Students: The Mediating Effects of Expression of Anger (대학생의 내현적 자기애와 데이트 폭력 가해와의 관계: 분노표현의 매개효과)

  • Nam, Gwi Suk;Lee, Soo Jin
    • Korean Journal of School Psychology
    • /
    • v.17 no.1
    • /
    • pp.87-107
    • /
    • 2020
  • The purpose of this study was to examine the mediating effect of functional and dysfunctional expressions of anger on the relationship between covert narcissism and dating violence among college students. The study also investigated gender differences with regard to covert narcissism, dating violence, and functional and dysfunctional expressions of anger. To this end, 339 college students (133 males, 206 females) with heterosexual dating experiences in the Busan Metropolitan area were recruited. They responded to the Covert Narcissism Scale, the Revised Conflict Tactics Scale 2, and the Korean adaptation of the State-Trait Anger Expression Inventory. The results were as follows. First, covert narcissism, dating violence, and functional and dysfunctional expressions of anger differed significantly by gender. Second, there were statistically significant correlations between covert narcissism, dating violence, and functional and dysfunctional expressions of anger. Third, multiple regression analysis showed that dysfunctional expressions of anger for males were positively correlated with dating violence while functional expressions of anger were negatively correlated. For females, dysfunctional expressions of anger were positively correlated with dating violence while functional expressions of anger were not significantly correlated. Fourth, dysfunctional expressions of anger completely mediated the relationship between covert narcissism and dating violence for both males and females, but functional expressions of anger had no mediating effect. These results suggest that dysfunctional anger expression control program should be developed for students which may help those with covert narcissistic tendencies to functionally express their anger. Future research should analyze dating violence prevention and counseling programs.

Effects of Exercise-Based Intervention Before and After Lung Cancer Surgery: A systematic review in pubmed database (허파암 수술 전과 후에 적용한 운동의 효과: PubMed 내 연구에 대한 체계적 문헌고찰)

  • Boram Oh;Heesu Kim;Sookyoung Park
    • Journal of The Korean Society of Integrative Medicine
    • /
    • v.11 no.2
    • /
    • pp.23-35
    • /
    • 2023
  • Purpose : Lung cancer induces a decrease in physical activity and a deterioration of respiratory ability. Exercise is an effective treatment to reduce side effects of anti-cancer treatments, also influence the survival and successful rehabilitation in lung cancer patients. However, there is insufficient evidence to show which period is the most effective to apply exercise for lung cancer patients. Therefore, this study was conducted to evaluate the efficacy of exercise-based interventions before and after surgery. Methods : Clinical trials (CTs) and randomized controlled trials (RCTs) reported in PubMed database were investigated. The trials investigated in this study were published for 10 years before August 20, 2022. The risk of bias was judged according to the Cochrane guideline. The materials included in this meta-analysis were 6-minute walk test (6MWT), pulmonary function, and quality of life (QOL). Results : 1 CT and 9 RCTs were selected in current study. In the meta-analysis, exercise increased 6MWT in preoperation (mean difference [MD] 29.49; 95 % confidence interval [CI] .99 to 57.99; p=.04; I2=0 %), 3 months postoperation (MD 54.97; 95 % CI 31.85 to 78.09; p<.001; I2=45 %) and 6 months postoperation (MD 85.59; 95 % CI 45.06 to 126.12; p<.001; I2=47 %). Exercise, also enhanced the lung function such as FEV1/FVC (%) in postoperation (MD 7.64; 95 % CI 6.26 to 9.02; p<.001; I2=19 %). Additionally, exercise improved QOL, such as preoperative EORTC-QLQ-C30-LC13 in mental function (MD 3.21; 95 % CI .64 to 5.79; p=.01; I2=0 %) and postoperative SF-36 in mental component summary (MD 9.24; 95 % CI 4.94 to 13.54; p<.001; I2=0%). Conclusion : These results indicate that exercise-based intervention can elevate the ability to exercise and the mental componentof QOL within 3 months.

Motivation for Alcohol Use, Problem Drinking, Family Alcohol Use and Dating Violence among College Students (음주 동기, 문제음주 및 음주 가족력과 대학생의 데이트 폭력)

  • Kyung Hyun Suh
    • Korean Journal of Culture and Social Issue
    • /
    • v.9 no.2
    • /
    • pp.61-78
    • /
    • 2003
  • The researcher examined the relationship between dating violence and drinking behaviors. Study participants included 440 Korean College students(184 males and 256 females) currently involved in heterosexual dating relationships. Participants' ages ranged from 17 to 30(M=20.08, SD=1.89). Questionnaires and psychological tests used included: Straus' Conflict Tactics Scale, Alcohol Use Disorder Identification Test(AUDIT), Cooper's Revised Drinking Motives Questionnaire(DMQ), and Index of Family Alcohol Use. Research designs were 2(gender) × 2(experience of inflicting dating violence), i.e. 2-way MANOVAs. Results suggest students who drink one or more times a week are more likely to commit acts of violence toward their dating partners than students drinking less often. The study revealed males tend to drink with higher social, enhancement, conformity and coping motives than females. The study also showed that students inflicting dating violence drank with higher coping motives than students who did not. Males showed more hazardous, dependent and harmful drinking patterns than females. Also, students who had inflicted dating violence showed a higher degree of these characteristics (hazardous, dependent and harmful drinking patterns) along with a greater family history of alcohol use than participants who had not inflicted dating violence. The findings showed significant 2-way interactions in dependent and harmful drinking patterns. Simple main effect analysis revealed that differences in dependent and harmful drinking patterns in males are more significant than the same differences in females.

  • PDF

Prognostic significance of sequential 18F-FDG PET/CT during frontline treatment of peripheral T cell lymphomas

  • Ga-Young Song;Sung-Hoon Jung;Seo-Yeon Ahn;Mihee Kim;Jae-Sook Ahn;Je-Jung Lee;Hyeoung-Joon Kim;Jang Bae Moon;Su Woong Yoo;Seong Young Kwon;Jung-Joon Min;Hee-Seung Bom;Sae-Ryung Kang;Deok-Hwan Yang
    • The Korean journal of internal medicine
    • /
    • v.39 no.2
    • /
    • pp.327-337
    • /
    • 2024
  • Background/Aims: The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemotherapy of patients with PTCLs. Methods: In total, 143 patients with newly diagnosed PTCLs were included. Sequential 18F-FDG PET/CTs were performed at the time of diagnosis, during chemotherapy, and at the end of chemotherapy. The baseline total metabolic tumor volume (TMTV) was calculated using the the standard uptake value with a threshold method of 2.5. Results: A baseline TMTV of 457.0 cm3 was used to categorize patients into high and low TMTV groups. Patients with a high TMTV had shorter progression-free survival (PFS) and overall survival (OS) than those with a low TMTV (PFS, 9.8 vs. 26.5 mo, p = 0.043; OS, 18.9 vs. 71.2 mo, p = 0.004). The interim 18F-FDG PET/CT response score was recorded as 1, 2-3, and 4-5 according to the Deauville criteria. The PFS and OS showed significant differences according to the interim 18F-FDG PET/CT response score (PFS, 120.7 vs. 34.1 vs. 5.1 mo, p < 0.001; OS, not reached vs. 61.1 mo vs. 12.1 mo, p < 0.001). Conclusions: The interim PET/CT response based on visual assessment predicts disease progression and survival outcome in PTCLs. A high baseline TMTV is associated with a poor response to anthracycline-based chemotherapy in PTCLs. However, TMTV was not an independent predictor for PFS in the multivariate analysis.