• 한국인터넷방송통신학회논문지
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• 제9권3호
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• pp.69-74
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• 2009

무선 채널은 유선 채널과 달리 시간적 공간적으로 지속적으로 변화하는 특성을 가지고 있으며 이는 네트워크의 성능 변화에도 많은 영향을 미치고 있다. 이러한 채널의 변화에 대응하여 네트워크의 성능을 향상하고자 하는 노력이 많이 이루어져 왔으며 이는 지역 통신으로 각광받고 있는 Wi-Fi도 예외는 아니다. 기존의 Wi-Fi 네트워크에서의 채널에 적응하여 역동적 속도 조절방식은 Flat-fading에 기반을 두어 이루어져 왔으나 대부분의 Wi-Fi 네트워크가 Indoor상황에서 이루어지기에 오히려 Frequency selective한 채널에 대응하는 방식의 속도 조절 방식이 요구되어지고 있다. 그러나 이러한 방식은 지속적으로 변화하는 채널에 적응하기에는 너무나 큰 overhead를 만들어 옴에 따라 적용되지 못하고 있었다. 본 논문에서는 각 sub-carrier별로 다양한 Rate를 적용할 수 있는 Layer-2 protocol을 제안한다. 제안된 프로토콜은 기존의 sub-carrier별 속도 조절시에 문제시 되는 overhead 의 증가문제를 단 한 개의 OFDM 심벌을 추가함으로써 혁신적으로 개선할 수 있었고 이를 통하여 네트워크의 성능 향상을 가져오게 되었다. 제안된 프로토콜은 simulation과정을 통하여 그 성능의 우월성을 입증하였다.

• 콘크리트학회논문집
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• 제27권2호
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• pp.147-155
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• 2015

본 연구에서는 기존 강도증진형 내진보강법의 단점을 보완 개선할 수 있는 새로운 개념의 내진보강법인 SRCF (Steel Reinforced Concrete Frame) 외부접합형 내진보강법을 제안하였다. SRCF 보강법은 거주자가 거주가 가능하면서 내진보강 공사를 실시할 수가 있으며, 접합부 시공성이 탁월하며, 특히 필요 내진보강량 산정이 간편한 전형적인 강도증진형으로 전단파괴가 지배적인 비내진상세를 가지는 국내 중 저층 철근콘크리트 건물에는 내력확보가 용이한 내진보강공법이다. 본 연구에서 제안한 SRCF 외부접합형 공법의 유용성을 검증 할 목적으로 기존 중 저층 철근콘크리트 학교건물의 골조를 대상으로 유사동적실험을 실시하여 내진보강효과를 검토하였다. 그 결과, 국내에서 발생 가능한 최대 지진규모(300gal)에서 비보강 골조는 붕괴를 하였지만, SRCF 외부접합형 내진보강법으로 보강한 골조는 경미한 지진피해가 예상되었으며, 대규모 지진(400, 500gal)을 상정한 경우에도 소규모 이하의 지진피해가 예상되어 본 연구에서 개발한 SRCF 내진보강법의 유효성이 검증되었다고 사료된다.

• International Journal of Oral Biology
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• 제45권1호
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• pp.15-24
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• 2020

The fruit of Chaenomeles sinensis (Thouin) Koehne (Chaenomelis Fructus) known as "Mo-Gua" in Korea has been commonly used in traditional medicine to treat inflammatory diseases, such as sore throat. However, its effect on bone metabolism has not been elucidated yet. Here, we examined the effect of Chaenomelis Fructus ethanol extract (CF-E) on receptor activator of nuclear factor (NF)-κB ligand (RANKL)-mediated osteoclast differentiation and formation. CF-E considerably inhibited osteoclast differentiation and tartrate-resistant acid phosphatase-positive multinuclear cell formation from bone marrow-derived macrophages and osteoclast precursor cells in a dose-dependent manner. In addition, the formation of actin rings and resorption pits were significantly suppressed in CF-E-treated osteoclasts as compared with the findings in non-treated control cells. Consistent with these phenotypic inhibitory results, the expressions of osteoclast differentiation marker genes (Acp5, Atp6v0d2, Oscar, CtsK, and Tm7sf4) and Nfatc1, a pivotal transcription factor for osteoclastogenesis, were markedly decreased by CF-E treatment. The inhibitory effect of CF-E on RANKL-induced osteoclastogenesis was associated with the suppression of NFATc1 expression, not by regulation of mitogen-activated protein kinases and NF-κB activation but by the inactivation of phospholipase C gamma 1 and 2. These results indicate that CF-E has an inhibitory effect on osteoclast differentiation and formation, and they suggest the possibility of CF-E as a traditional therapeutic agent against bone-resorptive diseases, such as osteoporosis, rheumatoid arthritis, and periodontitis.

• Journal of Ginseng Research
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• 제29권3호
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• pp.119-125
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• 2005

The previous reports demonstrated that ginseng saponins, active ingredient of Panax ginseng, inhibited blood vessel contraction induced by various hormones or high $K^+$. Recently, we demonstrated that 20(R)- and 20(S)-ginsenoside $Rg_3$. regulate ion channel activities with differential manners. The aim of this study was to examine whether ginsenoside $Rg_3$ isomers also show differential effects on swine coronary artery contractionresponses induced by high $K^+$, serotonin (5-HT) or acetylcholine. Treatment of 20(S)- but not 20(R)-ginsenoside $Rg_3$ caused a concentration-dependent relaxation of coronary artery contracted by 25mM KCI. 20(S)- and 20(R)-ginsenoside $Rg_3$ induced significant relaxations of coronary artery contraction induced by 5-HT $(3{\mu}M)$ in the presence of endothelium with concentration-dependent manner and, also in the absence of endothelium only 20(S)-ginsenoside $Rg_3$ induced a strong Inhibition of coronary artery contraction induced by 5-HT in a concentration-dependent manner. 20(S)-ginsenoside $Rg_3$ caused relaxation of coronary artery in the absence and presence of endothelium. In contrast, treatment of 20(S)- and 20(R)-ginsenoside $Rg_3\;(100{\mu}M)$ did not show significant inhibition of coronary artery contraction induced by acetylcholine $(0.01\;to\;30{\mu}M)$ in the presence of endothelium, whereas both isomers caused significant inhibition of coronary artery contraction induced by acetylcholine $(0.01\;to\;30{\mu}M)$ in the absence of endothelium in a concentration-dependent manner. These findings indicate that 20(S)-or 20(R)-ginsenoside $Rg_3$ exhibits differential relaxation eff3cts of swine coronary artery contractions caused by high $K^+$, acetylcholine, and 5-HT treatment and that this differential vasorelaxing effects of ginsenoside $Rg_3$ isomers also might be dependent on endothelium.

• 한국통신학회논문지
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• 제34권5B호
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• pp.455-462
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• 2009

본 논문에서는 다중 홉으로 구성된 IEEE 802.11 기반의 메쉬 네트워크에서 노드 간에 패킷 전송 시 버퍼 오버플로우에 의한 패킷 손실을 줄이고 수신되는 패킷의 공평성을 높이기 위한 버퍼 관리 방식을 제안한다. 제안된 방식은 전송 패킷을 전달하는 중간 노드에서 인접 메쉬 라우터와 이동 노드로부터 전송된 패킷을 균등하게 수신하고, 각 메쉬 라우터에서 다중 홉을 거친 패킷 수신율을 향상시킴으로써 패킷 전송지연과 노드의 에너지 소모를 줄일 수 있다. 제안된 방식은 기존의 IEEE 802.11 MAC 프로토콜 하에서 수정된 RTS/CTS를 이용하여 전송될 패킷의 크기를 미리 인지함으로써 패킷 손실과 패킷 공평성을 향상시킨다. 시뮬레이션을 이용하여 기존의 방식과 제안된 방식의 패킷 손실률, 각 메쉬 라우터에서 수신되는 패킷 양을 측정함으로써 제안된 방식의 성능을 비교 평가하였다.

• Journal of Communications and Networks
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• 제15권1호
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• pp.77-86
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• 2013

Cognitive radio (CR) has emerged as one of effective methods to enhance the utilization of existing radio spectrum. Main principle of CR is that secondary users (SUs) are allowed to use the spectrum unused by primary users (PUs) without interfering PU's transmissions. In this paper, PUs operate on a slot-by-slot basis and SUs try to exploit the slots unused by PUs. We propose OSA protocols in the single channel and we propose an opportunistic spectrum access (OSA) protocols in the multi-channel cognitive radio networks with one control channel and several licensed channels where a slot is divided into contention phase and transmission phase. A slot is divided into reporting phase, contention phase and transmission phase. The reporting phase plays a role of finding idle channels unused by PUs and the contention phase plays a role of selecting a SU who will send packets in the data transmission phase. One SU is selected by carrier sense multiple access / collision avoidance (CSMA/CA) with request to send / clear to send (RTS/CTS) mechanism on control channel and the SU is allowed to occupy all remaining part of all idle channels during the current slot. For mathematical analysis, first we deal with the single-channel case and we model the proposed OSA media access control (MAC) protocol by three-dimensional discrete time Markov chain (DTMC) whose one-step transition probability matrix has a special structure so as to apply the censored Markov chain method to obtain the steady state distribution.We obtain the throughput and the distribution of access delay. Next we deal with the multi-channel case and obtain the throughput and the distribution of access delay by using results of single-channel case. In numerical results, our mathematical analysis is verified by simulations and we give numerical results on throughput and access delay of the proposed MAC protocol. Finally, we find the maximum allowable number of SUs satisfying the requirements on throughput and access delay.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제3권4호
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• pp.125-128
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• 2014

OpenGL ES(OpenGL for Embedded System) 2.0은 현재 스마트 폰과 태블릿 PC에서 가장 널리 사용되고 있는 3차원 그래픽스 API표준이다. 이를 이용하는 개발과정에서는 상대적으로 성능이 떨어지는 모바일 환경보다는 데스크 탑 환경이 선호된다. 따라서, OpenGL 라이브러리만 제공되는 데스크 탑 환경에서, 모바일 그래픽스 환경에서의 OpenGL ES 2.0 API를 그대로 에뮬레이션 할 필요가 있다. 본 논문은 PC 상에서 OpenGL ES 2.0 을 에뮬레이션하기 위해, 기술적 문제점들을 극복하는 방법들과 이에 따른 구현 결과를 제시한다. 구현된 OpenGL ES 2.0 에뮬레이션 라이브러리는 데스크 탑 PC 상에서 동작하고, 공식적인 검증 테스트(conformance test suite)의 96%이상을 통과하여, 구현의 정확성을 보였다. 또한, 상업적으로 제공되는 벤치마크 프로그램들에 대한 테스트에서 기존의 상업적 구현 사례와 동등한 수행 속도를 보였다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제5권1호
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• pp.24-51
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• 2011

When supporting both voice and TCP in a wireless multihop network, there are two conflicting goals: to protect the VoIP traffic, and to completely utilize the remaining capacity for TCP. We investigate the interaction between these two popular categories of traffic and find that conventional solution approaches, such as enhanced TCP variants, priority queues, bandwidth limitation, and traffic shaping do not always achieve the goals. TCP and VoIP traffic do not easily coexist because of TCP aggressiveness and data burstiness, and the (self-) interference nature of multihop traffic. We found that enhanced TCP variants fail to coexist with VoIP in the wireless multihop scenarios. Surprisingly, even priority schemes, including those built into the MAC such as RTS/CTS or 802.11e generally cannot protect voice, as they do not account for the interference outside communication range. We present VAGP (Voice Adaptive Gateway Pacer) - an adaptive bandwidth control algorithm at the access gateway that dynamically paces wired-to-wireless TCP data flows based on VoIP traffic status. VAGP continuously monitors the quality of VoIP flows at the gateway and controls the bandwidth used by TCP flows before entering the wireless multihop. To also maintain utilization and TCP performance, VAGP employs TCP specific mechanisms that suppress certain retransmissions across the wireless multihop. Compared to previous proposals for improving TCP over wireless multihop, we show that VAGP retains the end-to-end semantics of TCP, does not require modifications of endpoints, and works in a variety of conditions: different TCP variants, multiple flows, and internet delays, different patterns of interference, different multihop topologies, and different traffic patterns.

• 대한두개안면성형외과학회지
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• 제16권1호
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• pp.11-16
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• 2015

Background: Source material used to fill calvarial defects includes autologous bones and synthetic alternatives. While autologous bone is preferable to synthetic material, autologous reconstruction is not always feasible due to defect size, unacceptable donor-site morbidity, and other issues. Today, advanced three-dimensional (3D) printing techniques allow for fabrication of titanium implants customized to the exact need of individual patients with calvarial defects. In this report, we present three cases of calvarial reconstructions using 3D-printed porous titanium implants. Methods: From 2013 through 2014, three calvarial defects were repaired using custom-made 3D porous titanium implants. The defects were due either to traumatic subdural hematoma or to meningioma and were located in parieto-occipital, fronto-temporo-parietal, and parieto-temporal areas. The implants were prepared using individual 3D computed tomography (CT) data, Mimics software, and an electron beam melting machine. For each patient, several designs of the implant were evaluated against 3D-printed skull models. All three cases had a custom-made 3D porous titanium implant laid on the defect and rigid fixation was done with 8 mm screws. Results: The custom-made 3D implants fit each patient's skull defect precisely without any dead space. The operative site healed without any specific complications. Postoperative CTs revealed the implants to be in correct position. Conclusion: An autologous graft is not a feasible option in the reconstruction of large calvarial defects. Ideally, synthetic materials for calvarial reconstruction should be easily applicable, durable, and strong. In these aspects, a 3D titanium implant can be an optimal source material in calvarial reconstruction.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 2005년도 창립30주년기념 추계 학술대회 및 정기총회
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• pp.41-63
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• 2005

Ginseng has been useful for the treatment of diverse disease in oriental countries for thousands of years. In addition, a folk medicine prescribed by seven herbal drugs including Panax ginseng has been antinarcotics in the treatment of morphine-dependent patients. Many articles have been reported on these works. Therefore, we review the protective effects of Panax ginseng on the neurotoxicity induced by abuse drugs. Ginseng total saponins (GTS) extracted and isolated by Panax ginseng antagonized morphine-induced analgesia, and inhibited the development of analgesic tolerance to and physical dependence on morphine. CTS inhibited morphine-6 dehydrogenase, which catalyzes production of mophinone from morphine, and increased hepatic glutathione level responsible to toxicity. Therefore, wehypothesized that these dual actions of ginseng can be associated with the detoxication of morphine. In addition, the inhibitory or facilitated effects of GTS on electrically evoked contraction in guinea pig ileum (${\mu}$-receptors) and mouse vas deferens(${\delta}$-receptors) were not mediated through opioid receptors, suggesting non-opioid mechanisms. On the hand, antagonism of U-50,488H (${\kappa}$-agonist)-induced antinociception is mediated by serotonergic mechanisms. GTS also inhibited hyperactivity, reverse tolerance (sensitization) and conditioned place preference-induced by psychostimulants such as methamphetamine, cocaine and morphine. On the other hand, GTS reduced the dopamine levels induced by methamphetamine. Moreover, GTS blocked the development of dopamine receptor activation, showing antidopaminergic effect. We suggest that GTS prevent the methamphetamine-induced striatal dopaminergic neurotoxicity. In addition, Ginsenoside also attenuates morphine-induced CAMP signaling pathway. These results suggested that GTS might be useful for the therapy of the adverse actions of drugs with abuse liability.