• Ocean and Polar Research
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• 제31권4호
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• pp.339-347
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• 2009

It is possible to obtain accurate temperature and salinity profiles of the oceans using a SBE 911plus CTD and accompanying data conversion packages. To obtain highly accurate results, CTD data needs to be carefully processed in addition to proper and regular maintenance of the CTD itself. Since the manufacturer of the CTD provides tools that are necessary for post processing, it is possible to conduct proper processing without too much effort. Some users, however, are not familiar with all of the processes and inadvertently ignore some of these processes at the expense of data quality. To draw attention to these and other similar issues, we show how it is possible to improve data quality by utilizing a few extra processes to the standard or default data process procedures with CTD data obtained from the equatorial Eastern Pacific between 2001 and 2005, and 2007. One easy step that is often ignored in the standard data process procedure is "wild edit", which removes abnormal values from the raw data. If those abnormal values are not removed, the abnormality could spread vertically during subsequent processes and produce abnormal salinity in a range much wider than that of the raw data. To remove spikes in salinity profiles the "align CTD" procedure must be carried out not with the default values included in the data processing software but with a proper time constant. Only when "cell thermal mass" correction is conducted with optimal parameters, we can reduce the difference between upcast and downcast, and obtain results that can satisfy the nominal accuracy of the CTD.

• Ocean and Polar Research
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• 제43권4호
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• pp.321-334
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• 2021

'Marine mammals-based observations' refers to data acquisition activities from marine mammals by instrumenting CTD (Conductivity-Temperature-Depth) sensors on them for recording vertical profiles of ocean variables such as temperature and salinity during animal diving. It is a novel data collecting platform that significantly improves our abilities in observing extreme environments such as the Southern Ocean with low cost compared to the other conventional methods. Furthermore, the system continues to create valuable information until sensors are detached, expanding data coverage in both space and time. Owing to these practical advantages, the marine mammals-based observations become popular to investigate ocean circulation changes in the Southern Ocean. Although these merits may bring us more opportunities to understand ocean changes, the data should be carefully qualified before we interpret it incorporating shipboard/autonomous vehicles/moored CTD data. In particular, we need to pay more attention to salinity correction due to the usage of an unpumped-CTD sensor tagged on marine mammals. In this article, we introduce quality control methods for the marine mammals-based CTD profiles that have been developed in recent studies. In addition, we discuss strategies of quality control specifically for the seal-tagging CTD profiles, successfully having been obtained near Terra Nova Bay, Ross Sea, Antarctica since February 2021. It is the Korea Polar Research Institute's research initiative of animal-borne instruments monitoring in the region. We anticipate that this initiative would facilitate collaborative efforts among Polar physical oceanographers and even marine mammal behavior researchers to understand better rapid changes in marine environments in the warming world.

• Ocean and Polar Research
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• 제36권1호
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• pp.77-85
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• 2014

The quality control of ocean observations data is becoming a major issue as real-time observational data and information services have increased recently. Therefore, it is necessary for oceanographic instruments to calibrate. In this paper, we first introduce the CTD calibration system and traceability. Next, CTD calibration procedures and estimation of uncertainty of measurement are described. The expanded uncertainty (k = 2) of the temperature, pressure and conductivity are 0.$0.003^{\circ}C$, $6.0{\times}10^{-5}$ and 0.006 mS/cm respectively. Finally, the excellence of CTD calibration and its measurement capability has been proven by comparing the inter-calibration result of KIOST and Sea-Bird Electronics (SBE). CTD calibration residuals are less than ${\pm}0.0001^{\circ}C$, ${\pm}0.001$ MPa, ${\pm}0.0001$ S/m for SBE 3plus temperature sensor, SBE 19plus pressure sensor and SBE 4C conductivity sensor respectively.

• Journal of Microbiology
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• 제43권6호
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• pp.516-522
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• 2005

The phosphorylation of C-terminal domain (CTD) of Rpb1p, the largest subunit of RNA polymerase II plays an important role in transcription and the coupling of various cellular events to transcription. In this study, its role in DNA damage response is closely examined in Saccharomyces cerevisiae, focusing specifically on several transcription factors that mediate or respond to the phosphorylation of the CTD. CTDK-1, the pol II CTD kinase, FCP1, the CTD phosphatase, ESS1, the CTD phosphorylation dependent cis-trans isomerase, and RSP5, the phosphorylation dependent pol II ubiquitinating enzyme, were chosen for the study. We determined that the CTD phosphorylation of CTD, which occurred predominantly at serine 2 within a heptapeptide repeat, was enhanced in response to a variety of sources of DNA damage. This modification was shown to be mediated by CTDK-1. Although mutations in ESS1 or FCP1 caused cells to become quite sensitive to DNA damage, the characteristic pattern of CTD phosphorylation remained unaltered, thereby implying that ESS1 and FCP1 play roles downstream of CTD phosphorylation in response to DNA damage. Our data suggest that the location or extent of CTD phosphorylation might be altered in response to DNA damage, and that the modified CTD, ESS1, and FCP1 all contribute to cellular survival in such conditions.

• 한국해양학회지:바다
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• 제9권4호
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• pp.204-211
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• 2004

자동 수직물성관측 뜰개는 매우 유용한 해양관측장비이지만 이에 부착된 CTD의 사후 보정이 불가능하기 때문에 뜰개자료의 정확도 검증이 사후자료관리나 자료활용에 있어 중요한 문제 중 하나이다. 동해 중심층의 염분변화가 국제 Argo프로그램에서 요구하는 정확도 0.01과 유사하기 때문에 동해를 항염분수조로 취급하여 동해에 투하된 뜰개가 관측한 염분자료의 신뢰성을 세 가지 방법을 통하여 검증하였다. 각각의 방법은 1)부근 해역에서 얻은 정확도가 높은 정선 CTD자료와 뜰개자료의 비교, 2)비슷한 시각에 비슷한 해역에서 얻은 뜰개자료의 비교, 3)체류 수심에서 얻은 염분자료의 장기간에 걸친 안정도 및 정확도 검증이다. 세 방법 모두 뜰개에서 얻은 염분자료가 아무런 보정없이도 Argo프로그램이 요구하는 정확도를 만족함을 보여주었다. 동해의 심층 수온이 일정하다는 가정하에 위의 세 가지 방법을 적용하여 얻은 수온값의 정확도 0.01$^{\circ}C$는 Argo프로그램에서 요구하는 정확도의 2배 정도이다. 하지만 동해의 중층 수온은 Argo프로그램이 요구하는 정확도 이상으로 시공간적으로 변화하기 때문에, 위의 결과는 수온 자료가 부정확하다는 것을 의미하지는 않는다. 동해 중층수온의 시공간적 변화를 고려한다면 수온자료의 정확도도 Argo프로그램이 요구하는 것과 큰 차이가 없다고 할 수 있다. 따라서 이 연구에서 검증된 뜰개가 관측한 수온 염분자료 모두 특별한 보정 없이 사용할 수 있다.

• 한국자기공명학회논문지
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• 제17권1호
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• pp.59-66
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• 2013

BldD, a developmental transcription factor from Streptomyces coelicolor, is a homodimeric, DNA-binding protein with 167 amino acids in each subunit. Each monomer consists of two structurally distinct domains, the N-terminal domain (BldD-NTD) responsible for DNA-binding and dimerization and the C-terminal domain (BldD-CTD). In contrast to the BldD-NTD, of which crystal structure has been solved, the BldD-CTD has been characterized neither in structure nor in function. Thus, in terms of structural genomics, structural study of the BldD-CTD has been conducted in solution, and in the present work, mainchain NMR assignments of the recombinant BldD-CTD (residues 80-167 of BldD) could be achieved by a series of heteronuclear multidimensional NMR experiments on a [$^{13}C/^{15}N$]-enriched protein sample. Finally, the secondary structure prediction by CSI and TALOS+ analysis using the assigned chemical shifts data identified a ${\beta}-{\alpha}-{\alpha}-{\beta}-{\alpha}-{\alpha}-{\alpha}$ topology of the domain. The results will provide the most fundamental data for more detailed approach to the atomic structure of the BldD-CTD, which would be essential for entire understanding of the molecular function of BldD.

• 한국보건간호학회지
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• 제17권2호
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• pp.266-277
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• 2003

In order to investigate the working conditions related to cumulative trauma disorder(CTD) and symptoms of CTD, a survey was conducted covering 305 employees who were working in three furniture manufacturing companies in Kyungin area. Data were collected by using questionnaire of the Personal Ergonomics Profiles. The results were as follows : 1. The mean score of working conditions related to CTD was 0.95. The mean score of working conditions for labor workers were significantly higher than that of clerical workers. Among 4 factors of working conditions, the higher score were shown in the working and environment factors with 1.22 and 1.18, respectively. 2. Symptom prevalence rate of CTD for workers was $81.0\%\;{;}\;82.9\%$ for labor workers and $77.0\%$ for clerical workers. As for symptom of CTD in body part, higher rate were shown in lower back with $50.2\%$, shoulder and neck with $38.4\%\;and\;36.4\%$ respectively. 3. The score of symptom severity of CTD were 3.45. Significant difference was shown in symptom severity of forearm and wrist/hand part between labor and clerical workers. As for symptom severity of CTD in body part the higher score were shown in shoulder, ankle/foot, forearm. lower leg and elbow. and the highest score for labor workers were shoulder and ankle/foot and for clerical workers was lower back. 4. As a whole, symptom of CTD for workers positively correlated to working conditions. 5. Symptom of CTD for workers seemed to be significantly influenced by working factor, sex, working duration and working area factor.

• 한국간호교육학회지
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• 제17권3호
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• pp.337-345
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• 2011

Purpose: This study was done to identify the relationship among Critical Thinking Disposition (CTD), stress of clinical practice and clinical competence in Korean nursing students. Methods: Participants were 407 baccalaureate nursing students (3rd and 4th grades) in Korea. Variables included CTD, stress of clinical practice, clinical competence, and demographic variables. Data was analyzed by frequencies, t-test, ANOVA, Pearson's correlation and multiple regression. Results: Clinical competence positively correlated with CTD, but negatively correlated with stress of clinical practice. The regression model explained 25.6% of clinical competence. The significant predictors of clinical competence were intellectual eagerness, intellectual fairness in CTD, conflict with patients, and clinical environment in stress of clinical practice. Conclusions: CTD and stress of clinical practice contribute to nursing student's clinical competence. Therefore, efforts to encourage nursing student's CTD, increase stress management skills, especially in conflict with patients, and build a supportive clinical environment should be made to strengthen clinical competence.

• Journal of the korean society of oceanography
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• 제35권4호
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• pp.192-199
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• 2000

Standard CTD data processing recommended by Sea-Bird Electronics produced thermal-lag corrections larger than 0.1 psu for the data taken during the CREAMS expeditions in the northern part of the East/Japan Sea where a vertical temperature gradient frequently exceeds 1.0$^{\circ}$C/m in the upper 100 m near the sea surface. As the standard processing is based upon a recursive filter which was introduced by Lueck and Pickle (1990), coefficients of the recursive filter have been newly derived for the CREAMS data by minimizing the difference between salinities of downcast and upcast in temperature-salinity domain. The new coefficients are validated by comparison with salinities measured by a salinometer, AUTOSAL 8400B. An accurate correction for the thermal-lag is critical in identifying water masses at intermediate depth in the East/japan Sea.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제34권1호
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• pp.37-44
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• 2023

Objectives: Tic disorders are highly heritable; however, growing evidence suggests that environmental factors play a significant role in their pathogenesis. Studies on these factors have been inconsistent, with conflicting results. Therefore, this study aimed to examine the associations of pre- and perinatal exposure to Tourette syndrome (TS) or chronic tic disorders (CTD) in Korean school-aged children. Methods: This case-control study used data from a large prospective cohort study. The primary outcome was TS/CTD diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria and Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version. Demographic, pre-, and perinatal information was obtained from the maternal questionnaires. Data between the TS/CTD and control groups were compared using the chi-squared or Student's t-test, as appropriate. Two-step logistic regression analyses were used to test the association between TS/CTD and pre- and perinatal risk factors. Results: We included of 223 children (78 with TS/CTD and 145 controls). Significant differences in the demographic data between the two groups were observed. The male sex ratio, mean parental age, parental final education level, and family history of tics were included as confounders. In the final adjusted multivariable model, TS/CTD was significantly associated with antiemetic exposure during pregnancy (odds ratio [OR]=16.61, 95% confidence interval [CI] 1.49-185.22, p=0.02) and medically assisted reproduction (OR=7.89, 95% CI 2.28-27.28, p=0.01). Conclusion: Antiemetic exposure and medically assisted reproduction are significantly associated with the risk of TS/CTD. These results should be replicated in future prospective and gene-by-environment studies.