• Title/Summary/Keyword: CTA

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CT Angiography-Derived RECHARGE Score Predicts Successful Percutaneous Coronary Intervention in Patients with Chronic Total Occlusion

  • Jiahui Li;Rui Wang;Christian Tesche;U. Joseph Schoepf;Jonathan T. Pannell;Yi He;Rongchong Huang;Yalei Chen;Jianan Li;Xiantao Song
    • Korean Journal of Radiology
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    • v.22 no.5
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    • pp.697-705
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    • 2021
  • Objective: To investigate the feasibility and the accuracy of the coronary CT angiography (CCTA)-derived Registry of Crossboss and Hybrid procedures in France, the Netherlands, Belgium and United Kingdom (RECHARGE) score (RECHARGECCTA) for the prediction of procedural success and 30-minutes guidewire crossing in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Materials and Methods: One hundred and twenty-four consecutive patients (mean age, 54 years; 79% male) with 131 CTO lesions who underwent CCTA before catheter angiography (CA) with CTO-PCI were retrospectively enrolled in this study. The RECHARGECCTA scores were calculated and compared with RECHARGECA and other CTA-based prediction scores, including Multicenter CTO Registry of Japan (J-CTO), CT Registry of CTO Revascularisation (CT-RECTOR), and Korean Multicenter CTO CT Registry (KCCT) scores. Results: The procedural success rate of the CTO-PCI procedures was 72%, and 61% of cases achieved the 30-minutes wire crossing. No significant difference was observed between the RECHARGECCTA score and the RECHARGECA score for procedural success (median 2 vs. median 2, p = 0.084). However, the RECHARGECCTA score was higher than the RECHARGECA score for the 30-minutes wire crossing (median 2 vs. median 1.5, p = 0.001). The areas under the curve (AUCs) of the RECHARGECCTA and RECHARGECA scores for predicting procedural success showed no statistical significance (0.718 vs. 0.757, p = 0.655). The sensitivity, specificity, positive predictive value, and the negative predictive value of the RECHARGECCTA scores of ≤ 2 for predictive procedural success were 78%, 60%, 43%, and 87%, respectively. The RECHARGECCTA score showed a discriminative performance that was comparable to those of the other CTA-based prediction scores (AUC = 0.718 vs. 0.665-0.717, all p > 0.05). Conclusion: The non-invasive RECHARGECCTA score performs better than the invasive determination for the prediction of the 30-minutes wire crossing of CTO-PCI. However, the RECHARGECCTA score may not replace other CTA-based prediction scores for predicting CTO-PCI success.

Assessing Abdominal Aortic Aneurysm Progression by Using Perivascular Adipose Tissue Attenuation on Computed Tomography Angiography

  • Shuai Zhang;Hui Gu;Na Chang;Sha Li;Tianqi Xu;Menghan Liu;Ximing Wang
    • Korean Journal of Radiology
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    • v.24 no.10
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    • pp.974-982
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    • 2023
  • Objective: Recent studies have highlighted the active and potential role of perivascular adipose tissue (PVAT) in atherosclerosis and aneurysm progression, respectively. This study explored the link between PVAT attenuation and abdominal aortic aneurysm (AAA) progression using computed tomography angiography (CTA). Materials and Methods: This multicenter retrospective study analyzed patients with AAA who underwent CTA at baseline and follow-up between March 2015 and July 2022. The following parameters were obtained: maximum diameter and total volume of the AAA, presence or absence of intraluminal thrombus (ILT), maximum diameter and volume of the ILT, and PVAT attenuation of the aortic aneurysm at baseline CTA. PVAT attenuation was divided into high (> -73.4 Hounsfield units [HU]) and low (≤ -73.4 HU). Patients who had or did not have AAA progression during the follow-up, defined as an increase in the aneurysm volume > 10 mL from baseline, were identified. Kaplan-Meier and multivariable Cox regression analyses were used to investigate the association between PVAT attenuation and AAA progression. Results: Our study included 167 participants (148 males; median age: 70.0 years; interquartile range: 63.0-76.0 years), of which 145 (86.8%) were diagnosed with AAA accompanied by ILT. Over a median period of 11.3 months (range: 6.0-85.0 months), AAA progression was observed in 67 patients (40.1%). Multivariable Cox regression analysis indicated that high baseline PVAT attenuation (adjusted hazard ratio [aHR] = 2.23; 95% confidence interval [CI], 1.16-4.32; P = 0.017) was independently associated with AAA progression. This association was demonstrated within the patients of AAA with ILT subcohort, where a high baseline PVAT attenuation (aHR = 2.23; 95% CI, 1.08-4.60; P = 0.030) was consistently independently associated with AAA progression. Conclusion: Elevated PVAT attenuation is independently associated with AAA progression, including patients of AAA with ILT, suggesting the potential of PVAT attenuation as a predictive imaging marker for AAA expansion.

Calix[6]arene Bearing Carboxylic Acid and Amide Groups in Polymeric CTA Membrane

  • Kim, Jong-Seung;Lee, Soo-Heon;Yu, Sang-Hyeok;Cho, Moon-Hwan;Kim, Dong-Won;Kwon, Seon-Gil;Lee, Eil-Hee
    • Bulletin of the Korean Chemical Society
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    • v.23 no.8
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    • pp.1085-1088
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    • 2002
  • Calix[6]arene having both carboxylic acid (1,3,5-) and carboxamide (2,4,6-) in an alternative way was synthesized. Transport rates of alkali and alkaline-earth metal ions were tested in bulk liquid membrane and polymer inclusion membrane. Ba2+ ion was found to give the highest transport rate among tested metal ions in both BLM and PIM systems. In PIM system, high durability (longer than 30 days) of the membrane was observed.

한국형 사이버 위협 정보 공유 기술 및 발전 방향

  • Lee, Hyun-Jin;Cho, Harksu
    • Review of KIISC
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    • v.31 no.5
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    • pp.47-54
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    • 2021
  • 사이버 보안 위협은 점차 은밀화·고도화되고 있어 단일 솔루션으로 탐지·분석이 어렵고, 파편화된 정보만으로 대응하는 데 한계가 있다. 이에 대응하기 위하여 글로벌 보안업체들은 CTA를 구성하여 신속 위협대응 체계를 구축하고 있다. 국내에서도 이에 발맞추어 다수의 보안 업체 및 기관들이 협업하여 2017년부터 3년간 Security Analytics 기반의 이기종 보안 솔루션 위협 분석 및 대응 기술 개발 과제를 수행하였다. 본 논문에서는 해당 과제의 수행성과 중 CTI 및 정보 공유 체계를 중심으로 정리하고 이를 통해 도출된 시사점과 현재 진행 방향을 정리하고자 한다.

Technical Survey of Eco-Green port (친환경 그린포트의 기술동향)

  • Kim, Kyung-Han;Park, Kyoung-Taik;Kim, Doo-Hyung;Cho, Gyu-Baeke
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2010.04a
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    • pp.167-168
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    • 2010
  • Advanced countries are adopted the Eco-Green port using high energy efficiency Crane and Automated unloading system. This paper includes the case study for energy saving ECO-RTG and other automated unloading system such as, German CTA, Japan OHI, and so on.

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Cyanobacterial bioreporters for detection of heavy metals, herbicide, and antibiotics (중금속, 제초제 및 항생제 검출용 남세균 유래 바이오 리포터)

  • Kim, Soo-Youn;Jeong, Won-Joong;Suh, Kye-Hong;Liu, Jang-Ryol;Park, Youn-Il
    • Journal of Plant Biotechnology
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    • v.35 no.2
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    • pp.141-145
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    • 2008
  • In this study, glucose-inducible intergenic sequences were used to generate bioreporters of the cyanobacterium Synechocystis sp. PCC 6803 that could monitor environmental pollutants. Luciferase genes LuxAB from the marine bacterium Vibrio fischeri under the control of glucose-inducible intergenic seqeucens of eight genes (atpI, ndbA, ctaD1, tkt, pgi, pdh, ppc, and cydA) were successfully expressed in the cyano-bacterial transformants, showing 5-25 fold increases in biolumeniscence upon exposure to glucose. In addition, glucose-inducible cyanobacterial bioreporters were very sensitive to various chemicals such as heavy metals ($Hg^{2+}$, $Cu^{2+}$, $Zn^{2+}$), electron transport inhibitors (DCMU, DBMIB, $CN^-$), and antibiotics (chloramphenicol and rifampicin). These glucose-inducible cyanobacterial bioreporters would be useful to develop biosensors for rapid screening of environmental samples.

Usefulness of High Resolution MRI in Confirmation of Mechanism:A Case Report (척추동맥폐색의 기전 확인에서 고해상도MRI의 유용성:증례 보고)

  • Hur, Wook;Kang, Hyun Goo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.7
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    • pp.239-244
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    • 2018
  • Both arterial dissection and atherosclerosis are major causes of cerebral infarction and appear to be occlusion or stenosis in magnetic resonance angiography(MRA) and computed tomographic angiography(CTA). But there are differences in treatment because they have different mechanisms. Recently, as high resolution magnetic resonance image(HR-MRI) develops, the image of blood vessel wall can be confirmed non-invasively. Though HR-MRI has become a very useful method for patients with suspected arterial dissection, differential diagnosis of the two diseases has not yet been fully established due to differences in the findings according to stages of arterial dissection and atherosclerosis. We investigated the differences between vertebral artery dissection and atherosclerosis through HR-MRI in two patients and confirmed the diagnosis by CTA follow-up. In addition to the previously established diagnostic criteria, we determined that the long and severe stenosis and recanalization suggest arterial dissection. Characteristics of arterial dissection confirmed by HR-MR and additional studies will be helpful for the treatment.

Evaluation of a Diffusive Sampler for the Measurement of Formaldehyde using Colorimetric Method (흡광광도법을 이용한 포름알데히드 확산측정기의 평가)

  • Yim, Bong-Been;Kim, Sun-Kyu;Jung, Eui-Suk;Kim, Sun-Tae
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.6
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    • pp.606-613
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    • 2005
  • The badge-type diffusive sampler for the measurement of formaldehyde in indoor air using three types of colorimetric methods such as chromotrophic acid(CTA), 3-methyl-2-benzothiazolinone hydrazone(MBTH), and 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole(AHMT) method. The washing of the collection filter with several cleaning solution was effected with satisfactory results, regardless of the types of cleaning solutions. The concentrations of absorbance solution in each colorimetric method were experimentally determined by considering the sampling rates. The variation blank values in each colorimetric method was below 15%. As compared with CTA and AHMT methods, the reproducibility of MBTH method was excellent and was below 10% relative standard deviation. The collected formaldehyde mass and time-weighted concentration had a good correlation (correlation coefficient > 0.93). The limit of detection and limit of quantitation, and minimum sampling time were closely correlated to the sampling rates for the measurement of formaldehyde in each method.

Congenital Hypoplasia of Internal Carotid Artery Accompanying with Cerebral Aneurysms

  • Baek, Geum-Seong;Koh, Eun-Jeong;Lee, Woo-Jong;Choi, Ha-Young
    • Journal of Korean Neurosurgical Society
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    • v.41 no.5
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    • pp.343-346
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    • 2007
  • Hypoplasia of the internal carotid artery is a rare congenital anomaly. Agenesis, aplasia, and hypoplasia of the internal carotid artery [ICA] are frequently associated with cerebral aneurysms in the circle of Willis. Authors report two cases with congenital hypoplasia of the ICA accompanying with the aneurysms. Transfemoral cerebral angiography [TFCA] in one patient identified nonvisualization of the left ICA. Bilateral anterior cerebral artery [ACA] and middle cerebral artery [MCA] were supplied from the right ICA accompanying with two aneurysms at anterior communicating artery [AcoA] and A1 portion of the left ACA. TFCA in another patient demonstrated hypoplastic left ICA and left ACA filled from the right ICA accompanying with AcoA aneurysm. Left MCA was filled from basilar artery via posterior communicating artery [PcoA]. Skull base computed tomography [CT] in two patients showed hypoplastic carotid canal. Authors performed direct aneurysmal neck clipping. Follow up CT angiography [CTA] at one year after surgery did not show regrowth or new development of the aneurysm. In patients with hypoplastic ICA, neurosurgeons should be aware of the possibility of development of the aneurysms, presumably because of hemodynamic process. Direct aneurysmal neck clipping is a good treatment modality. After operation, regular CTA, magnetic resonance angiography [MRA] or TFCA is needed to find progressive lesion and to prevent cerebrovascular attack [CVA].

Evaluate the diagnostic accuracy in the assessment of coronary artery stenoses using MDCT (MDCT를 이용한 관상동맥협착 진단의 정확성 평가)

  • Yang, Won-Seok;Sin, Sung-Gyu;Park, Jae-Hong
    • Journal of the Korean Society of Radiology
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    • v.6 no.4
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    • pp.275-279
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    • 2012
  • Methods and results : The suspected patient who have results of CTA and CAG examinations to evaluate coronary stenose to undergo each 16MD CT(n=93) and dual source CT(n=100). As a results of statistic, the highest rank of sensitivity, specificity, PPV, NPV and accuracy in coronary artery with using 16MDCT was displayed in LAD(73.5%), RCA(74.5%), LAD(66.7%), LCX(75%), LCX(67.7%). The mean diagnostic accuracy of dual source CT was more 17% than 16MDCT. Dual source CT was recorded 84% mean of accuracy. In addition to, segments of coronary artery did not show significant differences in all of them. However, distal segment become more and more accurate than proximal site.