• Proceedings of the Korea Society for Simulation Conference
• /
• 2000.11a
• /
• pp.180-185
• /
• 2000

방사선 치료계획이나 사전수술계획 등에 컴퓨터 사용이 늘어남에 따라 의료영상별 특성에 따른 복합적 처리를 필요로 한다. 본 논문에서는 다중 모달리티 영상으로부터 의미 있는 정보를 제공하기 위하여 상호정보 최적화를 통한 영상정합 방법을 제안한다. 본 방법은 두 영상에서 대응되는 위치의 명암도간 통계적 의존관계와 정보중복성을 계산하는 상호정보(mutual information)를 통해 영상간 변형관계를 추정함으로써 영상을 정합한다. 실험결과로는 뇌 자기공명영상(MRI)과 컴퓨터단층촬영영상(CT)의 상호정보를 최적화하여 정합 결과를 제시한다. 본 방법은 기존 정합방법에서 사용하는 영상분할이나 특징점 추출 등의 전처리 과정 없이 영상 자체 정보를 기반으로 계산함으로써 정합의 정확도를 높일 수 있다.

• Journal of International Society for Simulation Surgery
• /
• v.1 no.2
• /
• pp.83-86
• /
• 2014

Purpose This paper was purposed to suggest the method to produce the supportive helmet (head correction) for the infants who are suffering from plagiocephaly and to evaluate the level of transformation through 3D model. Method Either of CT or X-ray restored images has been used in making the supportive helmet (Head correction) in general, but these methods of measuring have problems in cost and safety. 3D surface measurement technology was suggested to solve such matters. Results It was to design the transformed model of the head within 0.7cm in average by scanning the surface of head and performing 3D restoration with marching cube and the changing rate of the head was compared in numerical data with 3D model. Conclusion The suggested methods displayed the better performance than the conventional method in respect of the speed and cost.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.29 no.4
• /
• pp.309-315
• /
• 2016

Recently, finite element analysis technique has been widely used for structural and mechanical understandings of human body in the dentistry field. This research proposed an effective finite element modeling method based on CT images, and parametric studies were performed for the occlusal simulation. The analyses were performed considering linear material behaviors and nonlinear geometrical effect, and validated with the experimental results. In addition, the skull models with two different molar relations such as Class I and full-CUSP Class II were generated and the analyses were performed using the proposed analytical method. As results, the relationships between the mandibular movement and occlusal force of both two models showed similar tendency in human occlusal force. However, stress was evenly distributed from teeth to facial bone in the skull model with Class I, while stress concentration was appeared in the model with full-CUSP Class II due to the changes of occlusal surfaces of the model.

• Journal of International Society for Simulation Surgery
• /
• v.1 no.2
• /
• pp.71-74
• /
• 2014

Purpose The prominent mandible angle, otherwise known as "square face", has been recognized as an aesthetic problem that needs correction by many in the Asian community. Many surgeons considered that mandible angle ostectomy alone, brings about hypotrophy of the masseter muscle. However, it was only proven indirectly (by clinical experience and histological animal experiments) and not objectively. In this study, we evaluated the volume of masseter muscle to prove the effect, objectively. Materials and method Computed tomography (CT) images were used to measure the masseter muscle volume of normal female group (n=6), and of female patient group n=8, preoperative and early & late postoperative volumes) presenting the symptom of prominent mandible angle. The data was analyzed statistically by two-sample t-test and paired t-test using SAS (version 8.2). Results In normal female group, volume average was $16,142{\pm}2,829.8mm^3$. In patient group, preoperative volume averaged $24,447{\pm}4,544.5mm^3$ (p<0.0001), early postoperative volume measured average of $31,966{\pm}50,421mm^3$ which is a 30% increase from the preoperative volume (p<0.0001). Late postoperative measurement was $20,202{\pm}4,092.3mm^3$, which is a 20% decrease from the preoperative volume (p<0.0006). Conclusion The bone reduction of prominent mandible angle induce the hypotrophic effect of masseter muscle after long term follow up (5 more months). This result mean that the result of mandible angle contouring surgery can be considered as combined effect of bony angle reduction and subsequent masseter muscle hypotrophy.

• Smart Structures and Systems
• /
• v.12 no.2
• /
• pp.97-119
• /
• 2013

This paper presents numerical and experimental results on the use of guided waves for structural health monitoring (SHM) of crack growth during a fatigue test in a thick steel plate used for civil engineering application. Numerical simulation, analytical modeling, and experimental tests are used to prove that piezoelectric wafer active sensor (PWAS) can perform active SHM using guided wave pitch-catch method and passive SHM using acoustic emission (AE). AE simulation was performed with the multi-physic FEM (MP-FEM) approach. The MP-FEM approach permits that the output variables to be expressed directly in electric terms while the two-ways electromechanical conversion is done internally in the MP-FEM formulation. The AE event was simulated as a pulse of defined duration and amplitude. The electrical signal measured at a PWAS receiver was simulated. Experimental tests were performed with PWAS transducers acting as passive receivers of AE signals. An AE source was simulated using 0.5-mm pencil lead breaks. The PWAS transducers were able to pick up AE signal with good strength. Subsequently, PWAS transducers and traditional AE transducer were applied to a 12.7-mm CT specimen subjected to accelerated fatigue testing. Active sensing in pitch catch mode on the CT specimen was applied between the PWAS transducers pairs. Damage indexes were calculated and correlated with actual crack growth. The paper finishes with conclusions and suggestions for further work.

• The KIPS Transactions:PartB
• /
• v.11B no.2
• /
• pp.133-140
• /
• 2004

Recently, the dental information systems were rapidly developed in order to store and process the data of patients. But, these systems should serve a doctor a good quality information against disease for diagnostic and surgery purpose so as to success in this field. This function of the system it important to persuade patients to undergo proper surgical operation they needed. Hence, 3D teeth model capable of simulating the dental surgery and treatment is necessary Teeth manipulation of dentistry is performed on individual tooth in dental clinic. io, 3D teeth reconstruction system should have the techniques of segmentation and 3D reconstruction adequate for individual tooth. In this paper, we propose the techniques of adaptive optimal segmentation to segment the individual area of tooth, and reconstruction method of tooth based on contour-based method. Each tooth can be segmented from neighboring teeth and alveolar bone in CT images using adaptive optimal threshold computed differently on tooth. Reconstruction of individual tooth using results of segmentation can be manipulated according to user's input and make the simulation of dental surgery and treatment possible.

• Progress in Medical Physics
• /
• v.16 no.4
• /
• pp.183-191
• /
• 2005

The utilization of PET has been increased so fast since the usefulness of the PET has been proved in various clinical and research fields. Among the many applications, the PET Is especially useful in oncology and most of the clinical PET scans are peformed for the oncologic examination Including the different diagnosis of malignant and benign tumors and assessment of the treatment effects and recurrent tumors. As the PET-CT scanners are widely available, there is Increasing interest in the application of the PET Images to the radiation treatment planning. Although the CT images are conventionally used for the target volume determination in the radiation treatment planning, there are fundamental limitation In use of only the anatomical information. Therefore, the volume determination of the functionally active tumor region using the PET would be important for the treatment planning. However, the accurate determination of the tumor boundary is not simple in PET due to the relatively low spatial resolution of the currently available PET scanners. In this study, computer simulations were peformed to study the relationship between the lesion size, PET resolution, lesion to background ratio and the threshold of Image Intensity to determine the true tumor volume.

• Journal of the Korean Society of Radiology
• /
• v.15 no.4
• /
• pp.401-408
• /
• 2021

Proton therapy using the Bragg peak is one of the radiation therapies and can deliver its maximum energy to the tumor with giving least energy for normal tissue. A cross-sectional image of the human body taken with the computed tomography (CT) has been used for radiation therapy planning. The HU values change according to the tube voltage, which lead to the change in the boundary and thickness of the anatomical structure on the CT image. This study examined the changes in the Bragg peak of the brain region according to the thickness variation in the head phantom composed of several materials using the Geant4. In the phantom composed of a single material, the Bragg peak according to the type of media and the incident energy of the proton beams were calculated, and the reliability of Geant4 code was verified by the Bragg peak. The variation of the peak in the brain region was examined when each thickness of the head phantom was changed. When the thickness of the soft tissue was changed, there was no change in the peak position, and for the skin the change in the peak was small. The change of the peak position was mainly changed when the bone thickness. In particular, when the bone was changed only or the bone was changed together with other tissues, the amount of change in the peak position was the same. It is considered that measurement of the accurate bone thickness in CT images is one of the key factors in depth-dose distribution of the radiation therapy planning.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.38 no.2
• /
• pp.179-190
• /
• 2001

In this proposed study, observing and analyzing contrast enhanced abdominal CT images, we segmented the liver automatically. We computed the ratio of each gray value from the estimated gray value range. With the average value of mesh image, we distinguished the liver from the noise parts. We divided the region based on immersion simulation. The threshold value is determined from the mesh image which is generated from each gray value portion of the liver and is used in dividing the liver to the noise region. To get the outline of the liver, we generated template image which represents the lump of the liver, and subtracted it from the binary image. With the results we use the proposed algorithm using 8-connectivity instead of the present opening algorithm, to reduce the processing time. We computed the volume from the segmented organ size and presented a clinical demonstration with the animal experiment

• Radiation Oncology Journal
• /
• v.33 no.2
• /
• pp.117-125
• /
• 2015

Purpose: To investigate the relationship between early treatment response to definitive chemoradiotherapy (CRT) and survival outcome in patients with limited stage small cell lung cancer (LS-SCLC). Materials and Methods: We retrospectively reviewed 47 patients with LS-SCLC who received definitive CRT between January 2009 and December 2012. Patients were treated with systemic chemotherapy regimen of etoposide/carboplatin (n = 15) or etoposide/cisplatin (n = 32) and concurrent thoracic radiotherapy at a median dose of 54 Gy (range, 46 to 64 Gy). Early treatment volume reduction rate (ETVRR) was defined as the percentage change in gross tumor volume between diagnostic computed tomography (CT) and simulation CT for adaptive RT planning and was used as a parameter for early treatment response. The median dose at adaptive RT planning was 36 Gy (range, 30 to 43 Gy), and adaptive CT was performed in 30 patients (63.8%). Results: With a median follow-up of 27.7 months (range, 5.9 to 75.8 months), the 2-year locoregional progression-free survival (LRPFS) and overall survival (OS) rates were 74.2% and 56.5%, respectively. The mean diagnostic and adaptive gross tumor volumes were 117.9 mL (range, 5.9 to 447 mL) and 36.8 mL (range, 0.3 to 230.6 mL), respectively. The median ETVRR was 71.4% (range, 30 to 97.6%) and the ETVRR >45% group showed significantly better OS (p < 0.0001) and LRPFS (p = 0.009) than the other group. Conclusion: ETVRR as a parameter for early treatment response may be a useful prognostic factor to predict treatment outcome in LS-SCLC patients treated with CRT.