• Title/Summary/Keyword: CST Analysis

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Therapeutic Efficacy and Safety of Prolonged Macrolide, Corticosteroid, Doxycycline, and Levofloxacin against Macrolide-Unresponsive Mycoplasma pneumoniae Pneumonia in Children

  • Ha, Seok Gyun;Oh, Kyung Jin;Ko, Kwang-Pil;Sun, Yong Han;Ryoo, Eell;Tchah, Hann;Jeon, In Sang;Kim, Hyo Jeong;Ahn, Jung Min;Cho, Hye-Kyung
    • Journal of Korean Medical Science
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    • v.33 no.43
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    • pp.268.1-268.11
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    • 2018
  • Background: We aimed to compare the therapeutic efficacy of prolonged macrolide (PMC), corticosteroids (CST), doxycycline (DXC), and levofloxacin (LFX) against macrolide-unresponsive Mycoplasma pneumoniae (MP) pneumonia in children and to evaluate the safety of the secondary treatment agents. Methods: We retrospectively analyzed the data of patients with MP pneumonia hospitalized between January 2015 and April 2017. Macrolide-unresponsiveness was clinically defined with a persistent fever of ${\geq}38.0^{\circ}C$ at ${\geq}72$ hours after macrolide treatment. The cases were divided into four groups: PMC, CST, DXC, and LFX. We compared the time to defervescence (TTD) after secondary treatment and the TTD after initial macrolide treatment in each group with adjustment using propensity score-matching analysis. Results: Among 1,165 cases of MP pneumonia, 190 (16.3%) were unresponsive to macrolides. The proportion of patients who achieved defervescence within 48 hours in CST, DXC, and LFX groups were 96.9% (31/33), 85.7% (12/14), and 83.3% (5/6), respectively. The TTD after initial macrolide treatment did not differ between PMC and CST groups (5.1 vs. 4.2 days, P = 0.085), PMC and DXC groups (4.9 vs. 5.7 days, P = 0.453), and PMC and LFX groups (4.4 vs. 5.0 days, P = 0.283). No side effects were observed in the CST, DXC, and LFX groups. Conclusion: The change to secondary treatment did not show better efficacy compared to PMC in children with macrolide-unresponsive MP pneumonia. Further studies are needed to guide appropriate treatment in children with MP pneumonia.

Finite element analysis of 2D turbulent flows using the logarithmic form of the κ-ε model

  • Hasebe, Hiroshi;Nomura, Takashi
    • Wind and Structures
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    • v.12 no.1
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    • pp.21-47
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    • 2009
  • The logarithmic form for turbulent flow analysis guarantees the positivity of the turbulence variables as ${\kappa}$ and ${\varepsilon}$ of the ${\kappa}-{\varepsilon}$ model by using the natural logarithm of these variables. In the present study, the logarithmic form is incorporated into the finite element solution procedure for the unsteady turbulent flow analysis. A backward facing step flow using the standard ${\kappa}-{\varepsilon}$ model and a flow around a 2D square cylinder using the modified ${\kappa}-{\varepsilon}$ model (the Kato-Launder model) are simulated. These results show that the logarithmic form effectively keeps adequate balance of turbulence variables and makes the analysis stable during transient or unsteady processes.

Gait Characteristic in a Stroke Patient with an Intact Corticospinal Tract and Corticoreticular Pathway: A Case Study

  • Yeo, Sang Seok;Cho, In Hee
    • The Journal of Korean Physical Therapy
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    • v.30 no.2
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    • pp.73-77
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    • 2018
  • Purpose: The prefrontal lobe, supplementary motor area, cerebellum, and basal ganglia are activated during gait. In addition, gait is controlled by nerves, such as the corticospinal tract (CST) and corticoreticular pathway (CRP). In this study, the presence of an injury to the CST and CRP was identified by diffusion tensor imaging and the characteristics of the gait pattern were investigated according to inferior cerebral artery infarction. Methods: One patient and six control subjects of a similar age participated. A 69-year-old female patient had an injury to the left basal ganglia, insular gyrus, corona radiata, dorsolateral prefrontal cortex, and postcentral gyrus due to an inferior cerebral artery infarction. Diffusion tensor imaging (DTI) data was acquired 4 weeks after the stroke. The kinematic and spatio-temporal parameters of gait were collected using a three-dimensional gait analysis system. Results: On 4 weeks DTI, the CST and CRP in the affected hemisphere did not show injury to the affected and unaffected hemisphere. Gait analysis showed that the cadence of spatio-temporal parameter was decreased significantly in the patient. The angle of the knee joint was decreased significantly in the affected and unaffected sides compared to the control group. Conclusion: The results of diffusion tensor imaging showed that although the patient was evaluated to be capable of an independent gait, the quality and quantity of gait might be reduced. This study could help better understand the gait ability analysis of stroke patients and the abnormal gait pattern of patients with a brain injury.

Monitoring Inductance Change to Quantitatively Analyze Magnetic Wear Debris in Lubricating Oil (인덕턴스 측정에 의한 윤활유 내 자성입자 정량적 평가)

  • Koo, HeeJo;Ahn, Hyo-Sok
    • Tribology and Lubricants
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    • v.32 no.6
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    • pp.189-194
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    • 2016
  • Wear debris in lubricating oil can be indicative of potential damage to mechanical parts in rotating and reciprocating machinery. Therefore, on-line or in-line monitoring of lubricating components in machinery is of great importance. This work presents a device based on inductive measurement of lubricating oil to detect magnetic wear particles in a tested volume. The circuit in the device consists of Maxwell Bridge and LVDT to measure inductance differences between pure and contaminated oil. The device detects the passage of ferrous particles by monitoring inductance change in a coil. The sensing principle is initially demonstrated at the microscale using a solenoid. The device is then tested using iron particles ranging from $50{\mu}m$ to $100{\mu}m$, which are often found in severely worn mechanical components. The test results show that the device is capable of detecting and distinguishing ferrous particles in lubricating oil. The design concept demonstrated here can be extended to an in-line monitoring device for real-time monitoring of ferrous debris particles. A simulation using the CST code is performed to better understand the inductive response in the presence of magnetic bodies in the oil. The CST simulation further verifies the effectiveness of inductance measurement for monitoring magnetic particles within a tube.

Design and Fabrication of 2.65GHz Antenna for Satellite-DMB (위성 DMB용 2.65GHz 안테나 설계 및 제작)

  • Ahn, Je-Sung;Ha, Deock-Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.12
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    • pp.2217-2226
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    • 2007
  • In this paper, we propose a microstrip antenna with sufficient impedance bandwidths and gains for the 2.65GHz antenna which can be used in the satellite digital multimedia broadcasting. The prposed 2.65GHz satellite DMB bandwidth microstrip antenna is implemented on a substrate, which is small enough to be installed in practical mobile phones, and described simulation feature using by CST MicroWave Studio program. And also, we measured the antenna performance between the proposed antenna and the commercial antenna. From the analysis, it was found that the radiation pattern of proposed antenna is superior to the commercial antenna and an acceptable frequency band is more wider than the existing products.

Vaginal Microbiota Profiles of Native Korean Women and Associations with High-Risk Pregnancy

  • Chang, Dong-Ho;Shin, Jongoh;Rhee, Moon-Soo;Park, Kyung-Ryang;Cho, Byung-Kwan;Lee, Sung-Ki;Kim, Byoung-Chan
    • Journal of Microbiology and Biotechnology
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    • v.30 no.2
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    • pp.248-258
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    • 2020
  • The vaginal microbiota may be important for pregnancy prognosis because vaginal dysbiosis during pregnancy appears to be related to preterm birth (PTB) or pregnancy loss. Previous reports have indicated that a Lactobacillus-poor microbial flora in the vagina and intrauterine infection by diverse anaerobes ascending from the vagina are associated with undesirable delivery outcomes. However, no research has involved the use of pyrosequencing analysis to examine vaginal microbiota profiles or their potential associations with high-risk pregnancy in Korean women. Vaginal swabs were collected from 500 Korean women for the identification of community state types (CSTs). Of these, 137 samples were further analyzed using a Roche/454 GS Junior pyrosequencer. Three distinct CSTs were identified based on the dominant vaginal microbes: CST I (Lactobacillus crispatus dominated), CST III (Lactobacillus iners dominated), and CST IV (with diverse species of anaerobes). Twelve of the 67 pregnant women had undesirable pregnancy outcomes (four miscarriages and eight PTBs). The dominant microbe in the vaginal microbiota of women who gave birth at full-term was L. crispatus. In contrast, L. iners was the dominant vaginal microbe in women who miscarried. Most (n = 6/8) vaginal microbiota profiles of women who experienced PTB could be classified as CST IV, with diverse bacteria, including anaerobic vaginal species. The present study provides valuable information regarding the characteristics of the vaginal microbiota of Korean women related to high-risk pregnancy. Investigation of the vaginal microbiotic structure in pregnant Korean women is necessary to enable better prediction of adverse pregnancy outcomes.

Managing Scheme for 3-dimensional Geo-features using XML

  • Kim, Kyong-Ho;Choe, Seung-Keol;Lee, Jong-Hun;Yang, Young-Kyu
    • Proceedings of the Korean Association of Geographic Inforamtion Studies Conference
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    • 1999.12a
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    • pp.47-51
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    • 1999
  • Geo-features play a key role in object-oriented or feature-based geo-processing system. So the strategy for how-to-model and how-to-manage the geo-features builds the main architecture of the entire system and also supports the efficiency and functionality of the system. Unlike the conventional 2D geo-processing system, geo-features in 3D GIS have lots to be considered to model regarding the efficient manipulation and analysis and visualization. When the system is running on the Web, it should also be considered that how to leverage the level of detail and the level of automation of modeling in addition to the support for client side data interoperability. We built a set of 3D geo-features, and each geo-feature contains a set of aspatial data and 3D geo-primitives. The 3D geo-primitives contain the fundamental modeling data such as the height of building and the burial depth of gas pipeline. We separated the additional modeling data on the geometry and appearance of the model from the fundamental modeling data to make the table in database more concise and to allow the users more freedom to represent the geo-object. To get the users to build and exchange their own data, we devised a fie format called VGFF 2.0 which stands for Virtual GIS File Format. It is to describe the three dimensional geo-information in XML(extensible Markup Language). The DTD(Document Type Definition) of VGFF 2.0 is parsed using the DOM(Document Object Model). We also developed the authoring tools for users can make their own 3D geo-features and model and save the data to VGFF 2.0 format. We are now expecting the VGFF 2.0 evolve to the 3D version of SVG(Scalable Vector Graphics) especially for 3D GIS on the Web.

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A Meta-analysis of the Effect of Walking Exercise on Lower Limb Muscle Endurance, Whole Body Endurance and Upper Body Flexibility in Elders (노인 걷기운동이 하지근지구력, 전신지구력과 상체유연성에 미치는 효과: 메타분석)

  • Roh, Kook-Hee;Park, Hyeoun-Ae
    • Journal of Korean Academy of Nursing
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    • v.43 no.4
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    • pp.536-546
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    • 2013
  • Purpose: The purpose of this study was to determine whether walking exercise improved physical function in elderly people using meta-analysis. Methods: Medical and nursing literature databases were searched to identify the studies on the effectiveness of walking exercise on physical function. In the databases, there were 16 articles reporting 21 interventions. Overall effect sizes for three outcome variables, elders' physical function in lower limb muscle endurance, whole body endurance and upper body flexibility, were calculated. Effects of study characteristics on outcome variables were analyzed. Results: The meta-analysis showed that walking exercise generally had positive effects on CST (chair stand test), 6MW (6 min walking), and SRT (standing or sitting reach test) with overall weighted effect sizes of 1.06, 0.41 and 0.29 respectively. This study also showed that the chronic disease status of the elders, intervention methods, and type of residence had different effects on CST, 6MW and SRT. Conclusion: The results indicate that walking exercise improves physical function in elders. Walking exercise which can be done at any time and any location is indeed a very effective exercise for elderly people.

Factors Associating Major Burn in Chemical Injury Patients due to Industrial Place Incident : A Retrospective study (산업장 화학 손상 환자에서 중증 화상에 영향을 미치는 요인)

  • Shin, Hee-Jun;Oh, Se-Kwang;Lee, Han-You
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.4
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    • pp.332-339
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    • 2016
  • This study examined the intensity of the association of factors affecting major burns by statistical analysis for patients injured by the release of chemical hazards. A total of 446 patients were evaluated as chemical injury patients, who had visited the emergency room from 1/Jan/2010 to 31/Dec/2014. The major burn was used as a dependent variable representing the severity of chemical injury. A chi-square test (CST) and binary logistic regression test (BLRA) were used as the statistical analysis method for determining the association between major burns and the independent variables. In CST, female and their presence at an incident scene, multiple site injury were associated with major burn (p<0.05). In BLRA, the presence at an incident scene and spills (comparing explosion), discharge (comparing admission) were associated with major burns (p<0.05). In this study, the presence at an incident scene was the most significant factor concerning major burns. Furthermore, gender and injury number, exposure mechanism (spill comparing explosion), and disposition (discharge comparing admission) were also associated with major burns.

Studies on Surface and Gas Reactions in a Catalytically Stabilized Combustor (촉매연소가 지원된 연소기에서의 표면반응과 가스반응에 관한 연구)

  • Seo, Yong-Seog;Yu, Sang-Phil;Jeong, Nam-Jo;Lee, Seung-Jae;Song, Kwang-Sup;Kang, Sung-Kyu
    • 한국연소학회:학술대회논문집
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    • 2003.12a
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    • pp.287-298
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    • 2003
  • A numerical investigation of a catalytically stabilized thermal (CST) combustor was conducted for a multi-channel catalyst bed, and both the catalyst bed and thermal combustor were simultaneously modeled. The numerical model handled the coupling of the surface and gas reaction in the catalyst bed as well as the gas reaction in the thermal combustor. The behavior of the catalyst bed was investigated at a variety of operating conditions, and location of the flame in the CST combustor was investigated via an analysis of the distribution of CO concentration. Through parametric analyses of the flame position, it was possible to derive a criterion to determine whether the flame is present in the catalyst bed or the thermal combustor for a given inlet condition. The results showed that the maximum inlet temperature at which the flame is located in the thermal combustor increased with increasing inlet velocity.

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