• Title/Summary/Keyword: CRP system

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On the Model Tests for POD Propulsion Ships

  • Go Seokcheon;Seo Heungwon;Chang Bong Jun
    • Journal of Ship and Ocean Technology
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    • v.9 no.1
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    • pp.1-10
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    • 2005
  • The procedures of model test and performance prediction for the CRP-POD propulsion ships, are studied. At the CRP-POD system, which are highly applicable to ultra large container carriers, RPM ratio of two propellers is not fixed, unlike conventional CRP system, and hence the power of each propeller must be predicted respectively. In this paper, a CRP-POD system is designed for 10,000 TEU class ultra large container carriers, and the characteristics of the CRP-POD system are experimentally studied. Finally, based on this study, the procedure of powering performance evaluation for CRP-POD propulsion ships is suggested. However, further studies on quantitative correction of the present procedure are required.

Transcriptional Regulatory System by CRP (CRP의 전사 조절계)

  • 최용락
    • Journal of Life Science
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    • v.2 no.1
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    • pp.2-10
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    • 1992
  • cAMP-CRP complex에 의해 전사조절을 받는 관련유전자의 구조, 특징, 조절양상, 기작과 CRP의 생화학적 및 분자생물학적이해 등을 살폈다. 그러나 대장균의 전체유전자의 구조해석이 연구사업으로 실행되어지고 있는 현실에서 볼 때 CRP의 조절하에 있는 유전자군이 보다 더 복잡 다양한 system으로 생각되어져서 CRP조절계의 전체적인 양상으로 해명하기 위한 연구도 이루어질 것으로 생각되어진다. 즉, cAMP-CRP의 조절하에 있는 조절영역의 전체를 파악함은 operon의 발현조절의 해명에 중요한 기틀이 될 뿐만 아니라 개별유전자의 이해를 위한 것보다 복잡한 세포 전체의 제어계를 분자적수준에서 해결하는데 중요한 과제라고 사료되어진다. 몇 가지 연구 결과에서는 cAMP-CRP가 결합은 하면서도 발현조절에는 관여하지 않는다든지, cAMP가 결합하지 않으면서도 전사조절을 받을 수 있는 유전자들이 밝혀지고 있다.

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A portable surface plasmon resonance sensor system for detection of C-reactive protein using SAM with dimer structure (소형 표면 플라즈몬 공명 센서와 이합체 구조를 가진 SAM을 이용한 CRP 검출)

  • Sin, Eun-Jung;Joung, Eun-Jung;Jo, Jin-Hee;Hwang, Dong-Hwan;Sohn, Young-Soo
    • Journal of Sensor Science and Technology
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    • v.19 no.6
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    • pp.456-461
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    • 2010
  • The detection of C-reactive protein(CRP) using self-assembled monolayer(SAM) was investigated by a portable surface plasmon resonance(SPR) sensor system. The CRP is a biomarker for the possible cardiovascular disease. The SAM was formed on gold(Au) surface to anchor the monoclonal antibody of CRP(anti-CRP) for detection of CRP. Sequence injection of the anti-CRP and bovine serum albumin(BSA) into the sensor system has been carried out immobilize the antibody and to prevent non-specific binding. The portable SPR system has two flow channels: one for the sample measurements and the other for the reference. The output SPR signal was increased with the injection of the anti-CRP, BSA and CRP due to binding of the proteins on the sensor chip. The valid output SPR signals was linearly related to the critical range of the CRP concentration. The experimental results showed the feasibility of the portable SPR system with newly developed SAM to diagnose a risk of the future cardiovascular events.

Study About a New Propulsion System Using CRP(II) (Noise and Flow of the Counter-Rotating Propeller) (CRP를 사용한 추진기관에 관한 연구(II) (CRP의 소음과 유동에 관하여))

  • 정진덕;이동호
    • Journal of the Korean Society of Safety
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    • v.10 no.2
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    • pp.39-45
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    • 1995
  • Three-dimensional flow measurements were conducted between the rotors of the CRP To understand mean flow phenomena of the CRP's, the results of the three-dimensional measurements were shown. Interaction noise of the CRP, which increases the overall ,level of sound pressure In the new propulsion system, is documented by using the double conditional sampling technique. The rear rotor will increase the axial flow between the rotors of a CRP depending upon the relative locations between the forward and the rear rotor blades. The decay and spreading of the forward wakes and the upstream propagation of the rear blade disturbances are shown along with the interaction of the flow disturbances by the two rotors of blades.

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Linear Drive Systems using Roller Gear Mechanism (롤러 기어 메커니즘을 이용한 직선이송시스템)

  • Kim, Chang-Hyun;Nam, Hyoung-Chul;Kwon, Soon-Man
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.21 no.5
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    • pp.702-707
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    • 2012
  • This paper considers two linear drive systems using roller gear mechanism(RGM), one is the RRP(roller rack pinion) system that consists of a roller rack and a cam pinion, the other is the CRP(cam rack pinion) system that consists of a cam rack and a roller pinion. Through the comparison of contact forces and load-stress factors between two linear drive systems, it reveals that the RRP system is superior to the CRP system in the aspect of the bending strength, while the CRP system has higher contact fatigue resistance than that of the RRP system.

Study About a New Propulsion System Using CRP( I ) (Flow interaction mechanism of a counter-rotating propeller) (CRP를 사용한 추진기관에 관한 연구( I ) (CRP의 유동상호작용에 관하여))

  • 정진덕;이동호
    • Journal of the Korean Society of Safety
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    • v.10 no.1
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    • pp.3-8
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    • 1995
  • The anemometer measurements were obtained from stationary hot-film probe mounted between the forward and rear rotors of a model CRP which rotated the forward and different directions. Data collection was done at several locations between rotors. To establish rotor-rotor interaction flow mechanism that contributes noise increasement of the CRP, methods of simple and the double condition-at sampling have been developed. The former uses to find similarity of the wake the later fixes the forward rotor position in time or space and permits averaging the mean wake at any fixed rotor angular location. The variation of the forward wake Is strongly depending upon the rear rotor location.

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Numerical investigation of the unsteady flow of a hybrid CRP pod propulsion system at behind-hull condition

  • Zhang, Yuxin;Cheng, Xuankai;Feng, Liang
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.12 no.1
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    • pp.918-927
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    • 2020
  • Flows induced by hybrid CRP pod propulsion systems (CRP-POD) are fundamentally characterized by unsteadiness. This work presents a numerical study on the unsteady flow of a CRP-POD at behind-hull condition based on CFD (Computational Fluid Dynamics). Unsteady RANS method is adopted, coupled with SST k-u turbulence model and sliding mesh method. The propeller thrusts and torques obtained by CFD is validated by model tests and acceptable agreements are obtained. The time histories of shingle-blade loads and pressures near the hull surface are recorded for the analysis of unsteady flow features. The cases of forward propeller alone and aft propeller alone are also computed to distinguish the hull-propeller interaction and propeller-propeller interaction. The results show the blade loads of both forward and aft propellers strongly fluctuate with phase angles. For the forward propeller, the blade load fluctuation is mainly governed by the hull-propeller interaction, while the aft blade load is remarkably affected by the propeller-propeller interaction in terms of the load average and fluctuation pattern. The fields of pressure, vorticity and velocity are also analyzed to reveal the unsteady flow features.

Expression of Escherichia coli DcuS-R Two-Component Regulatory System is Regulated by the Secondary Internal Promoter Which is Activated by CRP-cAMP

  • Oyamada, Tomoya;Yokoyama, Katsushi;Morinaga, Michiko;Suzuki, Masashi;Makino, Kozo
    • Journal of Microbiology
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    • v.45 no.3
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    • pp.234-240
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    • 2007
  • The DcuS-R two-component system of Escherichia coli senses $C_{4}-dicarboxylates$ of the medium and regulates expression of the genes related to utilization of them. It is known that phospho-DcuR induces expression of genes such as the dcuB-fumB operon, the frdABCD operon, and the dctA gene. We analyzed promoters of the dcuS-R operon to elucidate the transcriptional regulation system. We found a novel internal promoter within the dcuS gene that is regulated by the transcriptional regulator, CRP-cAMP, in both aerobic and anaerobic conditions.

Study on the Contra-Rotating Propeller system design and full-scale performance prediction method

  • Min, Keh-Sik;Chang, Bong-Jun;Seo, Heung-Won
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.1 no.1
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    • pp.29-38
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    • 2009
  • A ship's screw-propeller produces thrust by rotation and, at the same time, generates rotational flow behind the propeller. This rotational flow has no contribution to the generation of thrust, but instead produces energy loss. By recovering part of the lost energy in the rotational flow, therefore, it is possible to improve the propulsion efficiency. The contra-rotating propeller (CRP) system is the representing example of such devices. Unfortunately, however, neither a design method nor a full-scale performance prediction procedure for the CRP system has been well established yet. The authors have long performed studies on the CRP system, and some of the results from the authors' studies shall be presented and discussed.

Microparticle-based Immunonassay for the Detection of C-reactive Protein in Serum (미립자 응집반응을 이용한 C-reactive Protein의 면역 측정 법에 관한 연구)

  • 김재화;송은영;이희구;최용경;최명자;김용호;최인성;정태화
    • Biomedical Science Letters
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    • v.2 no.1
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    • pp.41-48
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    • 1996
  • The C-reactive protein(CRP) from ascitic and pleural fluid was purified using calcium dependent affinity chromatography of CNBr activated Sepharose-4B covalently coupled to p-diazonium phenylphosphorylcholine(DPPC) and hydroxylapitite chromatography. Polyclonal antibody was prepared from rabbit by immunizing the purified CRP. Specific immunoglobulin G was isolated using affinity chromatography and coupled to microparticles. A sensitive microparticle-based immunoassay was developed to measure CRP within 3 mins. The detection range was between 0.5mg/dl) and 20mg/dl in serum, showing strong response in the range of 0.7~2.9 mg/dl, weak response in 5.0~13.2 mg/dl and zone phenomenon over 28mg/dl. The average value of CRP in 74 samples was 3.8mg/dl and most of the values were lower than 10mg/dl .The CRP values of serum samples were determined by our microparticle-based immunoassay, and were compared with those obtained using the other commercial products(B Co., France and I Co., Japan). Good correlations were shown between the values obtained by our developed microparticle-based immunoassay system and those by other commercial products. All performance characteristics evaluated make our developed microparticles-based immunoassay suitable for a simple, rapid, and reliable screening of CRP in serum.

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