• International Journal of Industrial Entomology and Biomaterials
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• v.21 no.2
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• pp.169-174
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• 2010

Hydrolysate silk fibroin (HSF) is a fibrous protein composed of parallel $\beta$-structures and is made from pure silk elements including 18 amino acids, with glycine, alanine, and serine comprising of over 80% of the amino acids. Numerous studies have documented a range of effects of HSF, including moisturizing, antioxidant activity, nervous system disorders, and many more. We investigated whether HSF has anti-obesity effects in vitro. The effects of HSF inhibition on lipid accumulation and acceleration of lipid degradation in 3T3-L1 cells were studied. Treatment of 3T3-L1 cells with HSF caused significant inhibition of cell viability, an increase in glycerol release, and a decreased in adipocyte differentiation. Moreover HSF stimulated downregulated of adipogenic enzyme expressions (PPAR${\gamma}$ and C/EBP${\alpha}$) and up-regulated of fatty oxidation enzyme expressions (CPT-1 and UCP-2). Based on these results, hydrolysate silk fibroin can be suggested as a potential therapeutic substance as part of a prevention or treatment strategy for obesity.

• Corrosion Science and Technology
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• v.16 no.6
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• pp.278-284
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• 2017

The effects of TIG welding and post-treatment procedures on the microstructure and the pitting corrosion resistance of welded lean duplex stainless steel S82441 were investigated. Autogenous TIG welding was used with different amounts of heat input and shielding gases such as Ar, and mixtures of $Ar-N_2$ and Ar-He. The addition of 5% to 15% of nitrogen to argon practically did not affect the level of the pitting corrosion resistance. However, the application of gas mixtures (50% Ar + 50% He) resulted in a significant decrease in pitting corrosion resistance. We found that increased current (200 A and 250 A) led to lower values of CPT of welds compared with welds obtained with 50 A, 100 A and 150 A. In addition, the removal of the weld surface layer (0.2 ~ 0.3 mm thickness) in most cases not only resulted in a significant increase in resistance to the pitting corrosion but also post-treatment of weld, implying that corrosion resistance depended on factors such as surface roughness or the presence of undesirable oxides.

• Korean Journal of Optics and Photonics
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• v.16 no.1
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• pp.7-12
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• 2005

We have observed the nonlinear magneto-optic effect(NMOE) based on atomic coherence in $^{87}$ Rb D$_1$-line using the Rb vapor cell containing 50 Torr of Ne. The width of the NMOE signal was measured to be 2$\pi$${\times}$464 Hz, when the peak-to-peak B-field variation was 1 mGauss. The result of this work may be applied to a high-sensitivity magnetometer.

• Nutrition Research and Practice
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• v.2 no.4
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• pp.227-233
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• 2008

The aim of the present study was to assess the anti-obesity effects of grape seed extract (GSE) supplement in C57BL/6J mice. Thirty mice were divided into three groups; normal diet control group (ND), high fat diet control group (HD) and high fat diet plus grape seed extract supplemented group (HD+GSE). Results were as follows: 1. GSE supplement reduced the weight gain in mice fed high fat diets; epididymal and back fat weights, were lower compared to non-supplemented HD group. 2. Blood lipid concentrations were lower in the HD+GSE group than in the HD group. Serum HDL-C concentrations were higher in the HD+GSE group compared with the other groups. 3. The concentrations of acid-insoluble acylcarnitines, (AIAC) in serum and liver were higher in the HD+GSE group than in the HD group. 4. GSE supplementation increased mRNA levels of lipolytic genes such as carnitine palmitoyltransferase-l (CPT-1) and decreased mRNA levels of lipogenic genes such as acetyl CoA carboxylase (ACC). These findings suggest that grape seed extract supplements in high fat diet might normalize body weight, epididymal and back fat weights, lipid concentrations, and carnitine levels through controlling lipid metabolism.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.562-568
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• 2016

This study to investigated the therapeutic effect of robot-assisted rehabilitation (Lokomat) with virtual reality (VR) on Pusher syndrome (PS) after stroke. A total of 10 patients presented with PS after stroke were recruited. The participants were divided into two groups: Lokomat (n=5) and control groups (n=5). Lokomat and conventional physical therapy (CPT) were performed together in the experimental group, and the patients in the control group were treated with CPT only twice a day. One session of intervention was carried out for 30 minutes five times per week for 4 weeks. Scale for contraversive pushing (SCP), Berg balance scale (BBS), falling index (FI), and Timed up and go test (TUG) were measured before and after the intervention. The Lokomat group produced significantly better outcomes in SCP (p=0.046), BBS (p=0.046), FI (p=0.038), and TUG (p=0.038) compared with the control group after 4 weeks of intervention. In addition, there were significant correlations between SCP and BBS (p=0.024), FI (p=0.039), and TUG (p=0.030). In conclusion, Lokomat with VR more effectively aided recovery from PS after stroke, and restoration of PS symptoms was related with improvement of balance and gait function.

• Korean Journal of Biological Psychiatry
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• v.10 no.2
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• pp.147-158
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• 2003

Objective:The differences of various neurocognitive functions, including attention, memory, motor function, and higher cognitive function were compared between PTSD patients and normal control subjects. Also, correlation with PTSD symptom severity and neurocognitive functions were evaluated between PTSD patients and normal control subjects. Method:We assessed the neurocognitive functions by computerized neurocognitive test(CNT) batteries. The visual continuous performance test(CPT) and digit span test, finger tapping test and Wisconsin card sorting test(WCST) were executed. The Impact of Event Scale-Revised(IES-R) was used in the evaluation of the severity of PTSD. Result:The PTSD patients showed significantly impaired neurocognitive performance in all of the items, compared with normal control subjects. The relation between impairment in neurocognitive functions and symptom severity showed significant correlations. Conclusion:These results imply that PTSD patients have impaired neurocognitive functions concerning with specific brain areas, especially the frontal area. For the thorough evaluation of further neurocognitive functions, more detailed evaluation items of neurocognitive functions and brain imaging studies are necessary in the future study.

• Journal of Nutrition and Health
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• v.30 no.9
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• pp.1067-1072
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• 1997

One known effect of long chain n-3 polyunsaturated fatty acids is their ability to decrease plasma triglycerides. However, identification of the specific n-3 fatty acids and the underlying mechanisms responsible for this change remains uncertain. This present study was designed to evaluate the effects of moderate levels of dietary docosahexaenoic acid (22 :6(n-3)) on modulating plasma triglyderides. Male CD-1 mice were maintained for 15 days on identical diets containing either docosahexahexaenoic acid ethyl ester(1.5%, w/w) or linoleic acid(18 : 2(n-6)) ethyl ester (1.5%, w/w) . Plasma triglycerides were 40% lower in the docosahexaenoic acid group than in the linoleic acid group. Hepatic carnitine palmitoyltransferase activity (a key regulatory enzyme for mitocondria $\beta$-oxidation) was not significantly different between the dietary groups. However, plasma acid soluble acylcarnitine levels (which increase with increasing $\beta$-oxidation )were significantly higher in the decosahexaenoic acid group. This data suggests that plasma triglyceride levels are lower in mice fed diets containing moderate levels of docosahexaenoic acid compared to linoleic acid, but this effect on plasma triglycerides is not modulated through an augmentation of mitochondrial $\beta$-oxidation.

• Journal of Welding and Joining
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• v.13 no.4
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• pp.46-54
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• 1995

The cold cracking susceptibility of a variety of weld metals deposited by GMAW with several kinds of commercial solid wires for high strength-toughness steel was investigated. G-BOP test and LB-TRC test were carried out to study the effects of preheat, chemical composition and hydrogen level on the weld metal cold cracking. The results obtained are as follows. 1) 10% CPT obtained by G-BOP test was the most valuable criteria for evaluating the cold cracking susceptibility of weld metals compared with percentage of cracking at room temperature and crack free temperature, and it had good correlation with the results of LB-TRC test. 2) Cold cracking susceptibility of weld metals was high in the row of MG100A, MG100C, MG100D and MG100B. Welds deposited with MG130 and MG80 showed similar icidents of cracking with MG100C and MG100B respectively, even though their strength levels were different. 3) Diffusible hydrogen level in weld metals which has good relation with hydrogen content in wire itself was the most critical factor for controlling the cold cracking susceptibility of weld metal.

• Geotechnical Engineering
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• v.14 no.2
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• pp.79-92
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• 1998

Parametric studies based on laboratory pilot tests were performed to investigate the relationships between electrical resistivity and properties of contaminated soils. Three kinds of sandy soils sampled and leachate from an industrial waste landfill were mired to model the contaminated soils. Electrical resistivity of soils was measured by using a simulated resistivity cone penetrometer probe. In the experiments. the electrical resistivity was observed by changing the water content, void ratio, unit weight, degree of saturation, and concentration of the leachate. The test results show that the electrical resistivity of soils depends largely on the water content and the electrical property of pore water rather than unit weight and types of soils.

• Journal of the Korean Society for Railway
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• v.2 no.4
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• pp.9-19
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• 1999

The use of compaction grouting evolved in 1950's to correct structural settlement of buildings. Over the almost 50 years, the technology has been developed and is currently used in wide range of applications. Compaction grouting, the injection of a very stiff, 'zero-slump' mortar grout under relatively high pressure, displaces and compacts soils. It can effectively repair natural or man-made soil strength deficiencies in variety of soil formations. Major applications of compaction grouting include densifying loose soils or fill voids caused by sinkholes, poorly compacted fills, broken utilities, improper dewatering, or soft ground tunneling excavation. Other applications include preventing liquefaction, re-leveling settled structures, and using compaction grout bulbs as structural elements of minipiles or underpinning. In this paper, on the basis of the case history constructed in this year, a study has been performed to analyze the basic mechanism of the compaction grouting. Also, the effectiveness of the ground improvement and the bearing capacity of the compaction pile has been verified by the Cone Penetration Test(CPT) and Load Test. Relatively uniform compaction grouting column could be maintained by planning the quality control in the course of grouting. And, the Qualify Control Plan has been conceived using grout pressure, volume of grout and drilling depth.